PANTHER Gene Information

Gene Symbol(s):

Faf2

Organism:

Drosophila melanogaster

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Gene Name:

Fas-associated factor 2, isoform A

Gene ID:

FBgn0025608

Protein ID:

Q9VJ58

Persistent Id:

PTN000595126

Alternate Ids:

FBgn0025608(FlyBase)	35129(GeneID)
FBtr0081126(Ensembl_TRS)	FBpp0080670(Ensembl_PRO)
AE014134(EMBL)	Q9VJ58(Synonym)
FBgn0025608(Ensembl)	AAF53697(EMBL-CDS)
NM_058040(refSeq)	17137596(GI)
Q9VJ58_DROME(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	FAS-ASSOCIATED PROTEIN (PTHR23322)
PANTHER Subfamily:	FAS-ASSOCIATED FACTOR 2 (PTHR23322:SF1)
PANTHER GO-slim Molecular Function:	ubiquitin binding
PANTHER GO-slim Biological Process:	ERAD pathway
PANTHER GO-slim Cellular Component:	endoplasmic reticulum
PANTHER protein class:	scaffold/adaptor protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ubiquitin binding, protein-macromolecule adaptor activity
GO BP Complete:	ERAD pathway
GO CC Complete:	endoplasmic reticulum

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

RHO GTPase cycle, Signaling by Rho GTPases, RHOA GTPase cycle, Signal Transduction, Immune System, Innate Immune System, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Neutrophil degranulation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=24666\|UniProtKB=Q96CS3	Homo sapiens	LDO
GORGO\|Ensembl=ENSGGOG00000005506.3\|UniProtKB=A0A2I2Z620	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000009059.4\|UniProtKB=A0A1D5QU10	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1923827\|UniProtKB=Q3TDN2	Mus musculus	LDO
RAT\|RGD=1306577\|UniProtKB=Q5BK32	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000017744\|UniProtKB=Q2HJD0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000014057.5\|UniProtKB=A0A286ZMY6	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000012970.4\|UniProtKB=F6R8G3	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000030055.4\|UniProtKB=M3XCS5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845012363.1\|UniProtKB=A0A8I3NP54	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000005176.4\|UniProtKB=F7E7F8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011659.3\|UniProtKB=F6S6Z5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010010214.1\|UniProtKB=A0A8V0YCZ4	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000006247.3\|UniProtKB=H9GB58	Anolis carolinensis	LDO
XENLA\|Gene=faf2-b\|UniProtKB=Q6GQ69	Xenopus laevis	O
XENLA\|Gene=faf2-a\|UniProtKB=Q6AZH6	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-948050\|UniProtKB=Q28BP9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000007289.2\|UniProtKB=H2LSS2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-050208-312\|UniProtKB=B3DID0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000011889.1\|UniProtKB=W5N1W2	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004167.3\|UniProtKB=F7BPM3	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118404040\|UniProtKB=A0A9J7HG71	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC574675\|UniProtKB=A0A7M7N208	Strongylocentrotus purpuratus	LDO
PRIPA\|EnsemblGenome=WBGene00112041\|UniProtKB=A0A2A6CF72	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP007977\|UniProtKB=Q7Q3P6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC005087\|UniProtKB=D2CG01	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_197084\|UniProtKB=E9GJW2	Daphnia pulex	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_335122\|UniProtKB=E9HX39	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW011870\|UniProtKB=B7QCT9	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g243210\|UniProtKB=A7S6I6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g239607\|UniProtKB=A7RNK3	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g243784\|UniProtKB=A7S9M6	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG58970\|UniProtKB=B3S466	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_29028\|UniProtKB=A9V9W6	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_29043\|UniProtKB=A9V9Y3	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_25048\|UniProtKB=A9UXM1	Monosiga brevicollis	LDO
YEAST\|SGD=S000004475\|UniProtKB=Q04228	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADR182W\|UniProtKB=Q759U1	Eremothecium gossypii	LDO
YEAST\|SGD=S000002249\|UniProtKB=Q12229	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ADR276W\|UniProtKB=Q759K1	Eremothecium gossypii	O
CANAL\|CGD=CAL0000174468\|UniProtKB=A0A1D8PLX6	Candida albicans	O
CANAL\|CGD=CAL0000177382\|UniProtKB=Q5A0W1	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_D14784g\|UniProtKB=Q6C927	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00770\|UniProtKB=Q5BFB0	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G14320\|UniProtKB=Q4WS18	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01928\|UniProtKB=Q7SDP5	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_14154\|UniProtKB=A7F973	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_02490\|UniProtKB=Q0V0H4	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC285.11\|UniProtKB=O74498	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01585\|UniProtKB=B6JYC5	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNF00270\|UniProtKB=Q5KFX3	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02663\|UniProtKB=A0A0D1C6V9	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_19124\|UniProtKB=E3L9D9	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_87372\|UniProtKB=F4NZF5	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0291259\|UniProtKB=Q54EZ0	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_32019\|UniProtKB=F0ZI77	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0280423\|UniProtKB=Q54VE2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_77902\|UniProtKB=F0ZHZ1	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_35_1970\|UniProtKB=E9AF19	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb09.244.2680\|UniProtKB=Q38CY2	Trypanosoma brucei	LDO
PLAF7\|EnsemblGenome=PF3D7_0934700\|UniProtKB=Q8I2H1	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPS_7310\|UniProtKB=B5YNY3	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_5927\|UniProtKB=B8C524	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3H037_PHYRM\|UniProtKB=H3H037	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_04g230830v5\|UniProtKB=A0A2K3DUY4	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_03g200100v5\|UniProtKB=A0A2K3DZI1	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00030p00184390\|UniProtKB=U5D6Y6	Amborella trichopoda	LDO
SETIT\|EnsemblGenome=SETIT_029995mg\|UniProtKB=K3ZTR5	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3002G242800\|UniProtKB=A0A1B6QD87	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb316320\|UniProtKB=A0A1D6I6R5	Zea mays	O
ORYSJ\|EnsemblGenome=Os09g0482000\|UniProtKB=Q69QQ7	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_4g33395v3\|UniProtKB=I1IR56	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0489890\|UniProtKB=A0A8I6XPM1	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5A02G258700\|UniProtKB=A0A3B6KK69	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G257600\|UniProtKB=Q2L3V1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G266600\|UniProtKB=A0A3B6MTG8	Triticum aestivum	O
SPIOL\|Gene=LOC110797050\|UniProtKB=A0A9R0J0L2	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr02g0051481\|UniProtKB=A0A251VD51	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C100011410\|UniProtKB=A0A9R1WNH0	Lactuca sativa	O
CAPAN\|EnsemblGenome=T459_33419\|UniProtKB=A0A1U8FXW2	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400018167\|UniProtKB=M1BJM1	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc03g112630.3\|UniProtKB=A0A3Q7FS68	Solanum lycopersicum	O
TOBAC\|Gene=LOC107808860\|UniProtKB=A0A1S4BJ82	Nicotiana tabacum	O
TOBAC\|Gene=LOC107811590\|UniProtKB=A0A1S4BTB6	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi17g00873\|UniProtKB=F6GSL2	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_K02821\|UniProtKB=A0A059A5Z6	Eucalyptus grandis	O
GOSHI\|Gene=LOC107938061\|UniProtKB=A0A1U8MM29	Gossypium hirsutum	O
GOSHI\|Gene=LOC107946148\|UniProtKB=A0A1U8NA54	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_012158\|UniProtKB=A0A061FUR4	Theobroma cacao	O
POPTR\|EnsemblGenome=POPTR_015G080200v3\|UniProtKB=B9IEV2	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_06G107600\|UniProtKB=A0A2C9VRV0	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1509770\|UniProtKB=B9RAY4	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_17G087200\|UniProtKB=A0A0R0FL85	Glycine max	O
MEDTR\|EnsemblGenome=MTR_2g024420\|UniProtKB=I3T3U9	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_4g105430\|UniProtKB=A0A072UR40	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr02_03000\|UniProtKB=A0A2I4G1F2	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_1G046250\|UniProtKB=A0A0A0LR96	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_5G170100\|UniProtKB=M5W9K6	Prunus persica	O
ZOSMR\|Gene_ORFName=ZOSMA_28G00850\|UniProtKB=A0A0K9PET7	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma04_g23760\|UniProtKB=A0A804IT55	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma05_g10300\|UniProtKB=A0A804J2Y7	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_035511mg\|UniProtKB=K4A9F5	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G323000\|UniProtKB=C5WUN2	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb021210\|UniProtKB=B4FMI4	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb404660\|UniProtKB=B6TD00	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os10g0520600\|UniProtKB=Q9FWC4	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g31370v3\|UniProtKB=I1I5G8	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0050850\|UniProtKB=A0A8I6WTH7	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1A02G182700\|UniProtKB=A0A3B5XZC2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G198000\|UniProtKB=A0A3B5YXV3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G186100\|UniProtKB=A0A3B5ZTD9	Triticum aestivum	LDO
NELNU\|Gene=LOC104594217\|UniProtKB=A0A1U7ZW46	Nelumbo nucifera	O
NELNU\|Gene=LOC104604720\|UniProtKB=A0A1U8AJS6	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110796415\|UniProtKB=A0A9R0K3J2	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr02g0070161\|UniProtKB=A0A251VHZ6	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0603501\|UniProtKB=A0A251SUZ6	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr07g0283971\|UniProtKB=A0A251UAJ8	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600329860\|UniProtKB=A0A9R1VC70	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C300106380\|UniProtKB=A0A9R1W2B8	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C600302000\|UniProtKB=A0A9R1V5J8	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a006000mg\|UniProtKB=A0A022RUQ7	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_00049\|UniProtKB=A0A2G3AD71	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400012245\|UniProtKB=M1AWH8	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc08g082970.3\|UniProtKB=A0A3Q7HV82	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107830718\|UniProtKB=A0A1S4DKB5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107769345\|UniProtKB=A0A1S3XVS4	Nicotiana tabacum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400005799\|UniProtKB=M1A4Z9	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc08g008510.3\|UniProtKB=A0A3Q7HID1	Solanum lycopersicum	O
TOBAC\|Gene=LOC107823379\|UniProtKB=A0A1S4CWV6	Nicotiana tabacum	O
TOBAC\|Gene=LOC107799924\|UniProtKB=A0A1S4APS1	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi02g00205\|UniProtKB=F6HU62	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_D01693\|UniProtKB=A0A059CG29	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00044256001\|UniProtKB=A0A078JFA1	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra000721\|UniProtKB=M4C943	Brassica campestris	O
BRACM\|EnsemblGenome=Bra035277\|UniProtKB=M4F2H8	Brassica campestris	LDO
ARATH\|TAIR=locus=2132751\|UniProtKB=Q9M0N1	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107951184\|UniProtKB=A0A1U8NU67	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107950718\|UniProtKB=A0A1U8NSS6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107947170\|UniProtKB=A0A1U8NDX9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107947148\|UniProtKB=A0A1U8NDY4	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_015675\|UniProtKB=A0A061G2X5	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g012346mg\|UniProtKB=A0A067GMR6	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_003G145200v3\|UniProtKB=B9GXV5	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G085600v3\|UniProtKB=A0A2K2BUJ5	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G004500\|UniProtKB=A0A2C9W9M8	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1312920\|UniProtKB=B9RYS0	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_20G216900\|UniProtKB=I1NIG8	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G173300\|UniProtKB=I1LBY6	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g077740\|UniProtKB=A0A072VMS3	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr09_09440\|UniProtKB=A0A2I4EY82	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr02_15440\|UniProtKB=A0A2I4GKS3	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_5G011740\|UniProtKB=A0A0A0KL74	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G127400\|UniProtKB=M5WWL3	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_63727\|UniProtKB=D8R7G6	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_164130\|UniProtKB=D8QMR0	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c4_17110\|UniProtKB=A0A2K1KNT3	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c15_17250\|UniProtKB=A0A2K1JDH4	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c9_5600\|UniProtKB=A0A2K1K262	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0001s0291\|UniProtKB=A0A2R6XVY6	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_002330080\|UniProtKB=A0A1Y1IBC0	Klebsormidium nitens	LDO