PANTHER Gene Information

Gene Symbol(s):

Cox10

Organism:

Drosophila melanogaster

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Gene Name:

Protoheme IX farnesyltransferase, mitochondrial

Gene ID:

FBgn0032222

Protein ID:

Q9VKZ1

Persistent Id:

PTN000114286

Alternate Ids:

Q9VKZ1(Synonym)	34394(GeneID)
AAF52915(EMBL-CDS)	FBtr0079992(Ensembl_TRS)
7297663(GI)	AY058639(EMBL)
FBpp0079582(Ensembl_PRO)	NM_135538(refSeq)
Q9VKZ1_DROME(UniProtKB-ID)	FBgn0032222(Ensembl)
FBgn0032222(FlyBase)
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PANTHER Classification

PANTHER Family:	PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL (PTHR43448)
PANTHER Subfamily:	PROTOHEME IX FARNESYLTRANSFERASE, MITOCHONDRIAL (PTHR43448:SF2)
PANTHER GO-slim Molecular Function:	prenyltransferase activity
PANTHER GO-slim Biological Process:	heme biosynthetic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	acyltransferase

Pathway Categories:

Heme biosynthesis

Protoheme IX farnesyl transferase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	protoheme IX farnesyltransferase activity
GO BP Complete:	heme biosynthetic process, heme A biosynthetic process, respiratory chain complex IV assembly
GO CC Complete:	mitochondrion, membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Heme biosynthesis, Metabolism, Metabolism of porphyrins

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2260\|UniProtKB=Q12887	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000008790.4\|UniProtKB=H2QCB0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000012308.3\|UniProtKB=G3R9C8	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000016157.4\|UniProtKB=A0A5F8AR90	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1917633\|UniProtKB=Q8CFY5	Mus musculus	LDO
RAT\|RGD=1594623\|UniProtKB=F1LVF4	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015294.5\|UniProtKB=A5D7D6	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000018023.4\|UniProtKB=F1SS45	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000010334.6\|UniProtKB=M3WD36	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004049.1\|UniProtKB=A0A8I3MWL7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000008037.4\|UniProtKB=F6ZYP6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000038484.1\|UniProtKB=A0A6I8NMJ5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029941.1\|UniProtKB=Q5ZJY8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000017567.4\|UniProtKB=G1KU55	Anolis carolinensis	LDO
XENLA\|Gene=cox10.S\|UniProtKB=A0A1L8EN58	Xenopus laevis	O
XENLA\|Gene=cox10.L\|UniProtKB=Q0IH15	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-954608\|UniProtKB=B0BMH3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000011167.2\|UniProtKB=A0A3B3IGT9	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041111-239\|UniProtKB=F1QL30	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013147.1\|UniProtKB=W5N6D8	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118428691\|UniProtKB=A0A9J7M8U8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC580927\|UniProtKB=A0A7M7NPY9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00012895\|UniProtKB=K8ES01	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00029808\|UniProtKB=A8X566	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00304279\|UniProtKB=A0A8R1Z7Q0	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP008884\|UniProtKB=A0A1S4H085	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC034431\|UniProtKB=A0A139WBV5	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_57149\|UniProtKB=E9H174	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW008907\|UniProtKB=B7Q2X3	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG85716\|UniProtKB=T1G622	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g238754\|UniProtKB=A7RJI6	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG34046\|UniProtKB=B3SDN0	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_16299\|UniProtKB=A9UWY6	Monosiga brevicollis	LDO
YEAST\|SGD=S000006093\|UniProtKB=P21592	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AAL115W\|UniProtKB=Q75F43	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000197403\|UniProtKB=A0A1D8PNE8	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F23727g\|UniProtKB=Q6C0L2	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_01722\|UniProtKB=Q5BCK8	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G08340\|UniProtKB=Q4WP81	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU06141\|UniProtKB=Q7S5E7	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_04105\|UniProtKB=A7EFL4	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_00816\|UniProtKB=Q0V598	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC365.02c\|UniProtKB=Q9Y7Y4	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03173\|UniProtKB=B6K3I8	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNL04740\|UniProtKB=Q5K8R7	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_05692\|UniProtKB=A0A0D1CJ01	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_22769\|UniProtKB=H6QVK3	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_18956\|UniProtKB=E3L8R8	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_12223\|UniProtKB=F4P5K2	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0288169\|UniProtKB=Q54JB3	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_81366\|UniProtKB=F0ZT97	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_23_1520\|UniProtKB=Q4QAY6	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.5.1310\|UniProtKB=Q57VD2	Trypanosoma brucei	LDO
PLAF7\|EnsemblGenome=PF3D7_0519300\|UniProtKB=Q8I0W6	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00032241001\|UniProtKB=A0BTZ2	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00034822001\|UniProtKB=A0C3H6	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_15142\|UniProtKB=B8C4F6	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GG45_PHYRM\|UniProtKB=H3GG45	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_12g516350v5\|UniProtKB=A0A2K3D3S3	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00086p00025730\|UniProtKB=W1NYT0	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_56G00600\|UniProtKB=A0A0K9NVP1	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g16320\|UniProtKB=A0A804L8H5	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_001562mg\|UniProtKB=K3XI40	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G489700\|UniProtKB=A0A1B6QQ91	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb005400\|UniProtKB=B4FSK4	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb402310\|UniProtKB=K7VHB7	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0527700\|UniProtKB=Q5QLH9	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g40170v3\|UniProtKB=I1HNB4	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0007170\|UniProtKB=A0A8I6X1H0	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS1B02G051800\|UniProtKB=A0A3B5YRH6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G051900\|UniProtKB=A0A3B5YS96	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G040900\|UniProtKB=A0A3B5ZNR3	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0554680\|UniProtKB=A0A8I6YH62	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6A02G097000\|UniProtKB=A0A3B6NMC6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G110900\|UniProtKB=A0A3B6TE72	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G085400\|UniProtKB=A0A3B6QDI9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6B02G125500\|UniProtKB=A0A3B6PJ75	Triticum aestivum	LDO
NELNU\|Gene=LOC104606446\|UniProtKB=A0A1U8AQ62	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110783795\|UniProtKB=A0A9R0I7Z9	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr17g0819321\|UniProtKB=A0A251RSU6	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400172160\|UniProtKB=A0A9R1W1A6	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a017747mg\|UniProtKB=A0A022RIP7	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_14341\|UniProtKB=A0A2G2ZH59	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_03150\|UniProtKB=A0A2G3AM26	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400001672\|UniProtKB=M0ZN19	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc01g080860.3\|UniProtKB=A0A3Q7F1S6	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107829283\|UniProtKB=A0A1S4DFJ6	Nicotiana tabacum	O
TOBAC\|Gene=LOC107780480\|UniProtKB=A0A1S3YW14	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi15g00440\|UniProtKB=D7SM57	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_H02846\|UniProtKB=A0A059B2J0	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C04P05410.1\|UniProtKB=A0A078IC24	Brassica napus	O
BRACM\|EnsemblGenome=Bra004842\|UniProtKB=M4CKV6	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00022050001\|UniProtKB=A0A078GDJ0	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00045181001\|UniProtKB=A0A078GVD8	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra037646\|UniProtKB=M4F983	Brassica campestris	LDO
ARATH\|TAIR=locus=2042316\|UniProtKB=O64886	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107935205\|UniProtKB=A0A1U8MCF5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107890593\|UniProtKB=A0A1U8HX46	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_020446\|UniProtKB=A0A061EK72	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g015045mg\|UniProtKB=A0A067H3G3	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_002G216100v3\|UniProtKB=A0A2K2BME2	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_05G061000\|UniProtKB=A0A2C9VTR0	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1556410\|UniProtKB=B9SG90	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G293400\|UniProtKB=A0A0R0I7K2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_20G243400\|UniProtKB=I1NJ83	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g116110\|UniProtKB=G7IF26	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr14_02700\|UniProtKB=A0A2I4GMP6	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G127180\|UniProtKB=A0A0A0L3X5	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G571600\|UniProtKB=M5XW55	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_83494\|UniProtKB=D8R2F4	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_76844\|UniProtKB=D8QT70	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c14_19200\|UniProtKB=A0A2K1JID0	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0029s0153\|UniProtKB=A0A2R6X978	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003990050\|UniProtKB=A0A1Y1IIT3	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_1588\|UniProtKB=A9A606	Nitrosopumilus maritimus	O
NITMS\|EnsemblGenome=Nmar_1225\|UniProtKB=A9A5W6	Nitrosopumilus maritimus	LDO
KORCO\|EnsemblGenome=Kcr_0887\|UniProtKB=B1L5A4	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO0656\|UniProtKB=Q9UX46	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE1333\|UniProtKB=Q8ZXD4	Pyrobaculum aerophilum	O
PYRAE\|EnsemblGenome=PAE3597\|UniProtKB=Q8ZST3	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_4420\|UniProtKB=Q8THU1	Methanosarcina acetivorans	LDO
HALSA\|EnsemblGenome=VNG_0666G\|UniProtKB=Q9HRJ8	Halobacterium salinarum	LDO
STAA8\|EnsemblGenome=SAOUHSC_01066\|UniProtKB=Q2G2B9	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAD00135\|UniProtKB=Q8Y5K3	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_12080\|UniProtKB=O31652	Bacillus subtilis	O
BACSU\|EnsemblGenome=BSU_14880\|UniProtKB=P24009	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_3945\|UniProtKB=Q819N1	Bacillus cereus	LDO
PSEAE\|EnsemblGenome=PA1321\|UniProtKB=Q9I423	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM0439\|UniProtKB=Q8ZRC4	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_0763\|UniProtKB=Q0WCB5	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAE76208\|UniProtKB=P0AEA5	Escherichia coli	LDO
CHLAA\|EnsemblGenome=Caur_0029\|UniProtKB=A9WAQ6	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO1934\|UniProtKB=Q9XAC2	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv1451\|UniProtKB=P9WFR7	Mycobacterium tuberculosis	O
DEIRA\|EnsemblGenome=DR_2618\|UniProtKB=Q9RR78	Deinococcus radiodurans	O
GLOVI\|EnsemblGenome=BAC90107\|UniProtKB=Q7NIL7	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA10850\|UniProtKB=Q55500	Synechocystis	O
SYNY3\|EnsemblGenome=BAA18181\|UniProtKB=Q79EF2	Synechocystis	O
LEPIN\|EnsemblGenome=LA_0237\|UniProtKB=Q8F9F8	Leptospira interrogans	O
RHOBA\|EnsemblGenome=RB11931\|UniProtKB=Q7UJF4	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_154\|UniProtKB=O66544	Aquifex aeolicus	O
GEOSL\|EnsemblGenome=GSU0223\|UniProtKB=Q74GM3	Geobacter sulfurreducens	O
BRADU\|EnsemblGenome=BAC46437\|UniProtKB=Q9RM98	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_0996\|UniProtKB=Q83CV6	Coxiella burnetii	O
SHEON\|Gene_OrderedLocusName=SO_4614\|UniProtKB=Q8E8P7	Shewanella oneidensis	O
XANCP\|EnsemblGenome=XCC3824\|UniProtKB=Q8P487	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA0113\|UniProtKB=Q9I719	Pseudomonas aeruginosa	O