PANTHER Gene Information

Gene Symbol(s):

CG8891

Organism:

Drosophila melanogaster

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Gene Name:

Inosine triphosphate pyrophosphatase

Gene ID:

FBgn0031663

Protein ID:

Q9VMW7

Persistent Id:

PTN000116026

Alternate Ids:

AAF52191(EMBL-CDS)	Nucleoside-triphosphate diphosphatase {ECO:0000255\|HAMAP-Rule:MF_03148}(Synonym)
FBgn0031663(FlyBase)	FBpp0078684(Ensembl_PRO)
FBgn0031663(Ensembl)	33718(GeneID)
3.6.1.9 {ECO:0000255\|HAMAP-Rule:MF_03148}(EC)	74948245(GI)
ITPA_DROME(UniProtKB-ID)	NP_608890(refSeq)
AE014134(EMBL)	FBtr0079048(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	INOSINE TRIPHOSPHATE PYROPHOSPHATASE/HAM1 PROTEIN (PTHR11067)
PANTHER Subfamily:	INOSINE TRIPHOSPHATE PYROPHOSPHATASE (PTHR11067:SF9)
PANTHER GO-slim Molecular Function:	pyrophosphatase activity
PANTHER GO-slim Biological Process:	nucleoside triphosphate catabolic process
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	nucleotide phosphatase

Pathway Categories:

Thiamin metabolism

Nucleoside triphosphatase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	nucleoside triphosphate diphosphatase activity
GO BP Complete:	nucleoside triphosphate catabolic process
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Drug ADME, Metabolism, Purine catabolism, Ribavirin ADME, Nucleotide catabolism, Metabolism of nucleotides

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6176\|UniProtKB=Q9BY32	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000013194.4\|UniProtKB=H2QJV6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000008741.3\|UniProtKB=G3R067	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000061481.1\|UniProtKB=A0A5F7ZC08	Macaca mulatta	LDO
MOUSE\|MGI=MGI=96622\|UniProtKB=Q9D892	Mus musculus	LDO
RAT\|RGD=1589751\|UniProtKB=D3ZW55	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000013776\|UniProtKB=Q2KIC5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000035995.3\|UniProtKB=A0A480W0Q1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014049.3\|UniProtKB=A0A3Q2H414	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000040485.2\|UniProtKB=A0A337S394	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845005846.1\|UniProtKB=A0A8I3MSK5	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845015147.1\|UniProtKB=A0A8I3RYP7	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000005474.3\|UniProtKB=F7CG88	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000000904.4\|UniProtKB=A0A6I8P1W5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010013848\|UniProtKB=F1NLH9	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000012674.4\|UniProtKB=H9GJ52	Anolis carolinensis	LDO
XENLA\|Gene=itpa.S\|UniProtKB=A0A8J0V4V6	Xenopus laevis	O
XENLA\|Gene=LOC108714409\|UniProtKB=A0A8J1MZQ8	Xenopus laevis	O
XENLA\|Gene=itpa\|UniProtKB=Q2NLA8	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1001454\|UniProtKB=A0A6I8SWT3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000029653.1\|UniProtKB=A0A3B3HAQ1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070705-218\|UniProtKB=A5WVX0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010409.1\|UniProtKB=W5MWL6	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000014230\|UniProtKB=F6Y089	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118421903\|UniProtKB=A0A9J7LLU8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC583647\|UniProtKB=A0A7M7PLD9	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001823\|UniProtKB=Q9GYG4	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00040023\|UniProtKB=A8XZP2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00108177\|UniProtKB=A0A8R1YH73	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP008374\|UniProtKB=Q7Q4F5	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC014054\|UniProtKB=D6WJY1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_320031\|UniProtKB=E9GNM3	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW022372\|UniProtKB=B7QGF4	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG185734\|UniProtKB=T1FN78	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g163483\|UniProtKB=A7RWC9	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG21568\|UniProtKB=B3RNP5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_13033\|UniProtKB=A9VE54	Monosiga brevicollis	LDO
YEAST\|SGD=S000003830\|UniProtKB=P47119	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFR425C\|UniProtKB=Q752Z9	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000174774\|UniProtKB=Q59N80	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B22924g\|UniProtKB=Q6CDL9	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_03964\|UniProtKB=C8V5Y4	Emericella nidulans	O
EMENI\|EnsemblGenome=ANIA_08861\|UniProtKB=C8V9B7	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_8G00595\|UniProtKB=A4DA51	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_5G05560\|UniProtKB=Q4WTN9	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01441\|UniProtKB=Q1K4R6	Neurospora crassa	LDO
PHANO\|EnsemblGenome=SNOG_09421\|UniProtKB=Q0UFP3	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC830.10\|UniProtKB=Q9UU89	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03797\|UniProtKB=B6K531	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA03000\|UniProtKB=Q5KPF3	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02007\|UniProtKB=Q4PD06	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_06893\|UniProtKB=E3KAB5	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_13412\|UniProtKB=F4P9L8	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_192100\|UniProtKB=C4M750	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0286495\|UniProtKB=Q54LQ6	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_160300\|UniProtKB=F1A638	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_36_4630\|UniProtKB=Q4Q0V1	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.6k15.0290\|UniProtKB=Q389X7	Trypanosoma brucei	LDO
GIAIC\|Gene_ORFName=GL50803_007511\|UniProtKB=A0A644EZ43	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_210730\|UniProtKB=A2F859	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0720800\|UniProtKB=Q8IBP3	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00009235001\|UniProtKB=A0CPX6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005189001\|UniProtKB=A0BPH3	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_261492\|UniProtKB=B8BV98	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_30871\|UniProtKB=B8BQC8	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_1165\|UniProtKB=B8BQ53	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G9Z9_PHYRM\|UniProtKB=H3G9Z9	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_13g568950v5\|UniProtKB=A0A2K3CZI7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_02g095089v5\|UniProtKB=A8JEL2	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00120p00079170\|UniProtKB=W1NQH4	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_15G01340\|UniProtKB=A0A0K9PX41	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma04_g23120\|UniProtKB=A0A804ISW8	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_037577mg\|UniProtKB=K4AFC0	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G230200\|UniProtKB=C5WZH0	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb086240\|UniProtKB=A0A804MHP1	Zea mays	LDO
MAIZE\|EnsemblGenome=Zm00001eb425490\|UniProtKB=A0A804RG24	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb177140\|UniProtKB=A0A804NPZ6	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb102100\|UniProtKB=A0A804MPH5	Zea mays	LDO
MAIZE\|EnsemblGenome=Zm00001eb377030\|UniProtKB=A0A804R166	Zea mays	LDO
MAIZE\|EnsemblGenome=Zm00001eb046670\|UniProtKB=B6TNW8	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os10g0457500\|UniProtKB=Q7XDP2	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g27950v3\|UniProtKB=I1I4F4	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0039940\|UniProtKB=A0A8I6WRW3	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1B02G161200\|UniProtKB=A0A3B5YV26	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1A02G143800\|UniProtKB=A0A3B5XXM4	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS1D02G142600\|UniProtKB=A0A3B5ZRU2	Triticum aestivum	LDO
NELNU\|Gene=LOC104602141\|UniProtKB=A0A1U8AB76	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110778164\|UniProtKB=A0A9R0HWN4	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr01g0034271\|UniProtKB=A0A251VR03	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C100029190\|UniProtKB=A0A9R1WKQ4	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a014025mg\|UniProtKB=A0A022R1D6	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_07554\|UniProtKB=A0A2G2ZTZ1	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400029615\|UniProtKB=M1CWA0	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc09g091420.3\|UniProtKB=A0A3Q7J3W4	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107767540\|UniProtKB=A0A1S3XQ52	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107827163\|UniProtKB=A0A1S4D8E0	Nicotiana tabacum	O
TOBAC\|Gene=LOC107783471\|UniProtKB=A0A1S3Z628	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi05g00952\|UniProtKB=F6HS55	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_H00094\|UniProtKB=A0A059ATK7	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C04P42210.1\|UniProtKB=A0A078IR97	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra032731\|UniProtKB=M4EV98	Brassica campestris	LDO
ARATH\|TAIR=locus=2119420\|UniProtKB=Q8L968	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107890586\|UniProtKB=A0A1U8HX31	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_020402\|UniProtKB=A0A061ELY9	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g028718mg\|UniProtKB=A0A067EY21	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_003G175800v3\|UniProtKB=B9H013	Populus trichocarpa	LDO
POPTR\|EnsemblGenome=POPTR_001G052400v3\|UniProtKB=A0A2K2BSR1	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_03G152700\|UniProtKB=A0A2C9W7Q3	Manihot esculenta	LDO
MANES\|EnsemblGenome=MANES_15G048800\|UniProtKB=A0A2C9UE34	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1022280\|UniProtKB=B9RWM8	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G125100\|UniProtKB=A0A0R0I0E5	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_20G077400\|UniProtKB=C6TC28	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g047400\|UniProtKB=A0A072VHG8	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_1g047390\|UniProtKB=B7FMR3	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr07_13130\|UniProtKB=A0A2I4G8P1	Juglans regia	O
JUGRE\|EnsemblGenome=Jr07_13110\|UniProtKB=A0A2I4G8M3	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G133190\|UniProtKB=A0A0A0L4S4	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G060800\|UniProtKB=M5XZD6	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_86893\|UniProtKB=D8R7K8	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_74723\|UniProtKB=D8QML7	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c16_19640\|UniProtKB=A9SI54	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0026s0018\|UniProtKB=A0A2R6XAI5	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_003730020\|UniProtKB=A0A1Y1I9T7	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_1530\|UniProtKB=A9A4X2	Nitrosopumilus maritimus	LDO
KORCO\|EnsemblGenome=Kcr_1420\|UniProtKB=B1L6T7	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO0432\|UniProtKB=Q97ZZ0	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE2365\|UniProtKB=Q8ZVB5	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_3706\|UniProtKB=Q8TJS1	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_0226\|UniProtKB=Q57679	Methanocaldococcus jannaschii	LDO
HALSA\|EnsemblGenome=VNG_2043G\|UniProtKB=Q9HNL8	Halobacterium salinarum	LDO
THEKO\|EnsemblGenome=TK2111\|UniProtKB=Q5JEX8	Thermococcus kodakaraensis	LDO
CHLAA\|EnsemblGenome=Caur_0490\|UniProtKB=A9WE78	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO2902\|UniProtKB=Q9S2H9	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv1341\|UniProtKB=P9WMR7	Mycobacterium tuberculosis	LDO
CLOBH\|Gene_OrderedLocusName=CBO3261\|UniProtKB=A5I6Y8	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr1695\|UniProtKB=P64311	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_01107\|UniProtKB=Q2FZC5	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAC99317\|UniProtKB=Q8Y7N5	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_28360\|UniProtKB=P94558	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_4493\|UniProtKB=Q817P4	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_0159\|UniProtKB=Q9WY06	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_0179\|UniProtKB=Q9RXX6	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC88473\|UniProtKB=Q7NN81	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA18532\|UniProtKB=P74432	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_3666\|UniProtKB=Q8F031	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_3128\|UniProtKB=Q8A327	Bacteroides thetaiotaomicron	LDO
CHLTR\|EnsemblGenome=CT_606\|UniProtKB=O84611	Chlamydia trachomatis	LDO
RHOBA\|EnsemblGenome=RB5134\|UniProtKB=Q7UGM3	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_202\|UniProtKB=O66580	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A1837\|UniProtKB=B5YHP2	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_1337\|UniProtKB=B8E0G6	Dictyoglomus turgidum	LDO
NEIMB\|EnsemblGenome=NMB0639\|UniProtKB=Q9K0G6	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU1794\|UniProtKB=Q74C80	Geobacter sulfurreducens	LDO
BRADU\|EnsemblGenome=BAC45938\|UniProtKB=Q89WK5	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_0043\|UniProtKB=Q83FA3	Coxiella burnetii	LDO
HAEIN\|EnsemblGenome=HI_0260\|UniProtKB=P44598	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_3358\|UniProtKB=Q8EBY7	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_0456\|UniProtKB=Q9KUQ9	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC3253\|UniProtKB=Q8P5T3	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA0387\|UniProtKB=Q9I6A8	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM3103\|UniProtKB=Q8ZM45	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_3497\|UniProtKB=Q8ZHF4	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAE77017\|UniProtKB=P52061	Escherichia coli	LDO