PANTHER Gene Information   
Gene Symbol(s): Rheb
Organism: Drosophila melanogaster
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Gene Name: GTP-binding protein Rheb homolog
Gene ID: FBgn0041191
Protein ID: Q9VND8
Persistent Id: PTN000631890
Alternate Ids:
28571523(GI) AAF52004(EMBL-CDS)
Q0KIB7(AltAccession) NM_169069(refSeq)
FBgn0041191(Ensembl) RHEB_DROME(UniProtKB-ID)
117332(GeneID) AE014297(EMBL)
FBpp0078342(Ensembl_PRO) FBgn0041191(FlyBase)
FBtr0078694(Ensembl_TRS) Rheb(Symbol)
RHEB(Synonym)
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PANTHER Classification
PANTHER Family: RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY (PTHR24070)
PANTHER Subfamily: GTP-BINDING PROTEIN RHEB HOMOLOG (PTHR24070:SF226)  
PANTHER GO-slim Molecular Function: GTPase activity
carbohydrate derivative binding
anion binding
nucleotide binding
PANTHER GO-slim Biological Process: small GTPase-mediated signal transduction
PANTHER GO-slim Cellular Component: plasma membrane
PANTHER protein class: small GTPase
Pathway Categories: TGF-beta signaling pathway
   Ras-GDP
p53 pathway by glucose deprivation
   Ras homolog enriched in brain 2
TGF-beta signaling pathway
   Ras-GTP
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: GTP binding, GTPase activity, GDP binding
GO BP Complete: multicellular organism growth, positive regulation of translation, insulin receptor signaling pathway, response to starvation, terminal branching, open tracheal system, negative regulation of TORC2 signaling, cholesterol homeostasis, positive regulation of synaptic assembly at neuromuscular junction, positive regulation of ribosome biogenesis, positive regulation of cell growth, positive regulation of cell size, G1/S transition of mitotic cell cycle, apical protein localization, positive regulation of macroautophagy, positive regulation of TORC1 signaling, signal transduction, small GTPase-mediated signal transduction, lipid homeostasis, positive regulation of neuroblast proliferation, negative regulation of lipophagy, positive regulation of axon guidance, vascular endothelial growth factor receptor signaling pathway, negative regulation of autophagy, carbohydrate homeostasis, negative regulation of macroautophagy
GO CC Complete: membrane, plasma membrane
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Amino acids regulate mTORC1, Cellular responses to stress, Signal Transduction, Generic Transcription Pathway, Transcriptional Regulation by TP53, Regulation of PTEN gene transcription, Autophagy, Macroautophagy, Intracellular signaling by second messengers, Gene expression (Transcription), Cellular response to starvation, TOR signaling pathway, Insulin receptor mediated signaling, Cellular responses to stimuli, PTEN Regulation, TP53 Regulates Metabolic Genes, Drosophila signaling pathways, RNA Polymerase II Transcription, Energy dependent regulation of mTOR by LKB1-AMPK, MTOR signalling, PIP3 activates AKT signaling, mTORC1-mediated signalling

Orthologs