PANTHER Gene Information

Gene Symbol(s):

Hpd

Organism:

Drosophila melanogaster

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Gene Name:

4-hydroxyphenylpyruvate dioxygenase

Gene ID:

FBgn0036992

Protein ID:

Q9VPF3

Persistent Id:

PTN000238633

Alternate Ids:

7296311(GI)	AE014296(EMBL)
NP_730536(refSeq)	Q9VPF3_DROME(UniProtKB-ID)
AAS77442(EMBL-CDS)	FBgn0036992(Ensembl)
40263(GeneID)	Q9VPF3(Synonym)
FBtr0078225(Ensembl_TRS)	FBgn0036992(FlyBase)
FBpp0077883(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (PTHR11959)
PANTHER Subfamily:	4-HYDROXYPHENYLPYRUVATE DIOXYGENASE (PTHR11959:SF1)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
PANTHER GO-slim Biological Process:	aromatic amino acid family catabolic process tyrosine metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	oxygenase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	4-hydroxyphenylpyruvate dioxygenase activity
GO BP Complete:	aromatic amino acid metabolic process, tyrosine catabolic process
GO CC Complete:	endoplasmic reticulum membrane, Golgi membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism, Phenylalanine and tyrosine metabolism, Tyrosine catabolism, Metabolism of amino acids and derivatives

Orthologs

ID	Organism	Type
XENLA\|Gene=hpd-like.2.L\|UniProtKB=Q6PA53	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-986330\|UniProtKB=Q5BKL0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000011134.2\|UniProtKB=A0A3B3IJN7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-986\|UniProtKB=Q6TGZ5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003037.1\|UniProtKB=W5M5D0	lepisosteus oculatus	LDO
HUMAN\|HGNC=5147\|UniProtKB=P32754	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000005568.2\|UniProtKB=H2Q735	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011011.3\|UniProtKB=G3R601	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000016454.4\|UniProtKB=F7GF23	Macaca mulatta	O
MOUSE\|MGI=MGI=96213\|UniProtKB=P49429	Mus musculus	O
RAT\|RGD=61974\|UniProtKB=P32755	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000004175\|UniProtKB=Q5EA20	Bos taurus	O
PIG\|Gene=HPD\|UniProtKB=Q02110	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00005007869.1\|UniProtKB=A0A286ZK24	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000011561.4\|UniProtKB=F7BER4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000012105.6\|UniProtKB=M3WGC4	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845023604.1\|UniProtKB=A0A8I3PT65	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000012143.4\|UniProtKB=F7DI01	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000013190.3\|UniProtKB=A0A6I8NYV1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010025370.1\|UniProtKB=A0A8V1A7G1	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000011214.4\|UniProtKB=H9GHF1	Anolis carolinensis	O
XENLA\|Gene=hpd.L\|UniProtKB=Q5XHD8	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-955609\|UniProtKB=Q0IIY1	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000012993.2\|UniProtKB=H2MCJ9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040808-62\|UniProtKB=Q6AZV8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000005223.1\|UniProtKB=W5MD40	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000005482.3\|UniProtKB=F6PPW9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000015215.2\|UniProtKB=F6QXQ1	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118426065\|UniProtKB=A0A9J7LYP3	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC594130\|UniProtKB=A0A7M7RFK6	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00016294\|UniProtKB=Q18347	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG14622\|UniProtKB=A8XKB1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00001993\|UniProtKB=Q22633	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00037803\|UniProtKB=Q60Y65	Caenorhabditis briggsae	LDO
ANOGA\|EnsemblGenome=AGAP004802\|UniProtKB=Q7Q2T3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC012702\|UniProtKB=D6WZP4	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_327131\|UniProtKB=E9H9X2	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW018238\|UniProtKB=B7PHP6	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG186092\|UniProtKB=T1FNN4	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG64341\|UniProtKB=B3SAN2	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_32271\|UniProtKB=A9UYG6	Monosiga brevicollis	LDO
CANAL\|CGD=CAL0000180732\|UniProtKB=A0A1D8PHL9	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_B21846g\|UniProtKB=Q6CDR5	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_01899\|UniProtKB=C8VKK0	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G10620\|UniProtKB=Q4WPV8	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_2G04200\|UniProtKB=Q4WHU1	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01830\|UniProtKB=Q872T7	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_07630\|UniProtKB=A7EQM8	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_01560\|UniProtKB=Q0V354	Phaeosphaeria nodorum	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_36439\|UniProtKB=F4NV92	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0273429\|UniProtKB=Q557J8	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_158589\|UniProtKB=F1A1Z5	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0277511\|UniProtKB=Q76NV5	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_97354\|UniProtKB=F0ZG03	Dictyostelium purpureum	O
DICPU\|EnsemblGenome=DICPUDRAFT_91266\|UniProtKB=F0ZA46	Dictyostelium purpureum	LDO
PARTE\|EnsemblGenome=GSPATT00003696001\|UniProtKB=A0E6B4	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00000389001\|UniProtKB=Q6BG80	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_5371\|UniProtKB=B8C2R0	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_32153\|UniProtKB=B8BU80	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G6L3_PHYRM\|UniProtKB=H3G6L3	Phytophthora ramorum	LDO
PHYRM\|Gene=H3G8A0_PHYRM\|UniProtKB=H3G8A0	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_09g398993v5\|UniProtKB=A0A2K3DET7	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_09g399030v5\|UniProtKB=Q70ZL8	Chlamydomonas reinhardtii	LDO
ZOSMR\|Gene_ORFName=ZOSMA_38G01320\|UniProtKB=A0A0K9P4P0	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma09_g31220\|UniProtKB=A0A804KQR3	Musa acuminata subsp. malaccensis	LDO
SORBI\|EnsemblGenome=SORBI_3002G105600\|UniProtKB=A0A1W0W3D1	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3002G104200\|UniProtKB=C5X3I2	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb304950\|UniProtKB=A0A1D6HX48	Zea mays	O
BRADI\|EnsemblGenome=BRADI_4g11450v3\|UniProtKB=I1IJR8	Brachypodium distachyon	O
WHEAT\|EnsemblGenome=TraesCS1D02G102000\|UniProtKB=A0A3B5ZS15	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G035800\|UniProtKB=A0A3B5YS13	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_017353mg\|UniProtKB=K3YSV8	Setaria italica	O
SETIT\|EnsemblGenome=SETIT_017217mg\|UniProtKB=K3YSH3	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G053700\|UniProtKB=C5XVJ3	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb232960\|UniProtKB=A0A1D6H1G0	Zea mays	LDO
BRADI\|EnsemblGenome=BRADI_3g05060v3\|UniProtKB=I1HXM3	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0567270\|UniProtKB=F2CV61	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G169700\|UniProtKB=A0A3B6PKV0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G141500\|UniProtKB=A0A3B6NLC6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G004200\|UniProtKB=A0A3B5YPS2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G130800\|UniProtKB=A0A3B6QF06	Triticum aestivum	LDO
NELNU\|Gene=LOC104609470\|UniProtKB=A0A1U8BC10	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110803794\|UniProtKB=A0A9R0JC01	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr02g0081271\|UniProtKB=A0A251VJ25	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C600314840\|UniProtKB=A0A9R1VCH0	Lactuca sativa	O
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0656041\|UniProtKB=A0A251SNC3	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C200085730\|UniProtKB=A0A9R1WHS2	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C200085720\|UniProtKB=A0A9R1XVT4	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a005210mg\|UniProtKB=A0A022RQN3	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_14664\|UniProtKB=A0A1U8GPG9	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400017420\|UniProtKB=M1BGV3	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc07g045050.3\|UniProtKB=A0A3Q7I6Z0	Solanum lycopersicum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400017707\|UniProtKB=M1BHZ7	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc05g041200.3\|UniProtKB=A0A3Q7HCX5	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107774621\|UniProtKB=A0A1S3YCH2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107832751\|UniProtKB=A0A1S4DRQ6	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi12g00071\|UniProtKB=F6H586	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_A02024\|UniProtKB=A0A059DH15	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_A02023\|UniProtKB=A0A059DG67	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_A02022\|UniProtKB=A0A059DGQ8	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C05P04810.1\|UniProtKB=A0A078F6T2	Brassica napus	O
BRACM\|EnsemblGenome=Bra015511\|UniProtKB=M4DG88	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C08P51160.1\|UniProtKB=A0A078FAB5	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra032415\|UniProtKB=M4EUD3	Brassica campestris	LDO
ARATH\|TAIR=locus=2009160\|UniProtKB=P93836	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107920131\|UniProtKB=A0A1U8KWK9	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_001977\|UniProtKB=A0A061DM42	Theobroma cacao	O
THECC\|EnsemblGenome=TCM_001968\|UniProtKB=A0A061DL13	Theobroma cacao	O
THECC\|EnsemblGenome=TCM_001963\|UniProtKB=A0A061DK60	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g013898mg\|UniProtKB=A0A067EDA6	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_002G057400v3\|UniProtKB=A0A2K2BE26	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G088900\|UniProtKB=A0A2C9WC90	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1192240\|UniProtKB=B9S300	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_14G180200\|UniProtKB=A0A0R0GEM8	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_02G284600\|UniProtKB=K7KBB9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_14G030400\|UniProtKB=I1M6Z4	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_5g090990\|UniProtKB=G7K3B8	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_5g090980\|UniProtKB=G7K3B7	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_1g022325\|UniProtKB=A0A072VDQ2	Medicago truncatula	O
MEDTR\|EnsemblGenome=MTR_5g091060\|UniProtKB=Q56H33	Medicago truncatula	LDO
JUGRE\|Gene=LOC109019209\|UniProtKB=A0A2I4HLG0	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G608160\|UniProtKB=A0A0A0KZ39	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G177700\|UniProtKB=A0A251Q205	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_165961\|UniProtKB=D8QY42	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_91092\|UniProtKB=D8RCB8	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_161008\|UniProtKB=D8T4S6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_174278\|UniProtKB=D8RUV1	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c2_15470\|UniProtKB=A9RV71	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c1_27020\|UniProtKB=A9RPY0	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0126s0038\|UniProtKB=A0A2R6W8Z8	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000460150\|UniProtKB=A0A1Y1HN93	Klebsormidium nitens	LDO