PANTHER Gene Information

Gene Symbol(s):

CHMP2B

Organism:

Drosophila melanogaster

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Gene Name:

Charged multivesicular body protein 2b

Gene ID:

FBgn0035589

Protein ID:

Q9VRJ5

Persistent Id:

PTN000049645

Alternate Ids:

AY061433(EMBL)	Q9VRJ5(Synonym)
FBgn0035589(Ensembl)	AAF50800(EMBL-CDS)
NP_647947(refSeq)	7295486(GI)
38599(GeneID)	Q9VRJ5_DROME(UniProtKB-ID)
FBpp0076869(Ensembl_PRO)	FBgn0035589(FlyBase)
FBtr0077166(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	CHARGED MULTIVESICULAR BODY PROTEIN (PTHR10476)
PANTHER Subfamily:	CHARGED MULTIVESICULAR BODY PROTEIN 2B (PTHR10476:SF40)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	endosome transport via multivesicular body sorting pathway late endosome to vacuole transport protein transport
PANTHER GO-slim Cellular Component:	membrane protein complex late endosome endosome membrane
PANTHER protein class:	membrane traffic protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	molecular_function
GO BP Complete:	protein transport, endosome transport via multivesicular body sorting pathway, endosomal transport, late endosome to vacuole transport, vacuolar transport
GO CC Complete:	ESCRT III complex, multivesicular body

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Endosomal Sorting Complex Required For Transport (ESCRT), Nuclear Envelope (NE) Reassembly, Cell Cycle, Sealing of the nuclear envelope (NE) by ESCRT-III, M Phase, Cell Cycle, Mitotic, Mitotic Anaphase, Macroautophagy, Autophagy, Mitotic Metaphase and Anaphase, Membrane Trafficking, Vesicle-mediated transport

Orthologs

ID	Organism	Type
HUMAN\|HGNC=24537\|UniProtKB=Q9UQN3	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000015122.5\|UniProtKB=K7C9W0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000024679.2\|UniProtKB=G3SJW8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000016246.4\|UniProtKB=F7GEL2	Macaca mulatta	O
MOUSE\|MGI=MGI=1916192\|UniProtKB=Q8BJF9	Mus musculus	O
RAT\|RGD=1306781\|UniProtKB=F1M8B7	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000007939\|UniProtKB=Q3SX42	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000011997.5\|UniProtKB=A0A287A1F6	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000011997.5\|UniProtKB=A0A287A1F6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000010433.4\|UniProtKB=F6QV41	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845025997.1\|UniProtKB=A0A8I3PS98	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000016939.4\|UniProtKB=F6VMU4	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000048121.1\|UniProtKB=A0A6I8P668	Ornithorhynchus anatinus	O
CHICK\|Gene_ORFName=RCJMB04_25h19\|UniProtKB=Q5F3A2	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010007680.1\|UniProtKB=A0A8V0XTN8	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000039394.1\|UniProtKB=A0A803SQP3	Anolis carolinensis	O
XENLA\|Gene=chmp2b-b\|UniProtKB=Q66IV6	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-948820\|UniProtKB=Q6NVL7	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000015878.2\|UniProtKB=H2MME5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-070628-3\|UniProtKB=B0UXH0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010544.1\|UniProtKB=W5MX11	lepisosteus oculatus	O
XENLA\|Gene=chmp2b-a\|UniProtKB=Q7SYR0	Xenopus laevis	LDO
XENLA\|Gene=chmp2b.S\|UniProtKB=A0A8J0UHW9	Xenopus laevis	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2539\|UniProtKB=Q6NXD2	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000012097.2\|UniProtKB=F6XUK1	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118407581\|UniProtKB=A0A9J7HQH4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC587068\|UniProtKB=A0A7M7PJV6	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00007216\|UniProtKB=O02208	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG20395\|UniProtKB=A8XXP2	Caenorhabditis briggsae	LDO
TRICA\|EnsemblGenome=TC005451\|UniProtKB=D6WYH0	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_303881\|UniProtKB=E9GIQ3	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW019894\|UniProtKB=B7PRV9	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG167737\|UniProtKB=T1EZQ6	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g184920\|UniProtKB=A7S2L3	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG25101\|UniProtKB=B3RXS0	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_22088\|UniProtKB=A9UPJ0	Monosiga brevicollis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_86558\|UniProtKB=F4NX48	Batrachochytrium dendrobatidis	LDO
GIAIC\|EnsemblGenome=GL50803_7323\|UniProtKB=A8BHQ3	Giardia intestinalis	LDO
PARTE\|EnsemblGenome=GSPATT00033776001\|UniProtKB=A0BZF6	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_bd196\|UniProtKB=B8LE78	Thalassiosira pseudonana	LDO
CHLRE\|EnsemblGenome=CHLRE_17g735400v5\|UniProtKB=A0A2K3CRC8	Chlamydomonas reinhardtii	LDO
ZOSMR\|Gene_ORFName=ZOSMA_25G01470\|UniProtKB=A0A0K9PFN2	Zostera marina	O
MUSAM\|EnsemblGenome=Ma07_g00970\|UniProtKB=A0A804JQT4	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma04_g38280\|UniProtKB=A0A804IYH1	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma05_g02240\|UniProtKB=A0A804IZX9	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_037391mg\|UniProtKB=K4AET4	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G158300\|UniProtKB=C5WR95	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb218770\|UniProtKB=A0A804P9N5	Zea mays	O
ORYSJ\|EnsemblGenome=Os03g0639800\|UniProtKB=Q6ASS4	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g13950v3\|UniProtKB=I1GQ29	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0508630\|UniProtKB=F2EHV6	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5B02G379400\|UniProtKB=A0A3B6LRH2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCSU02G072600\|UniProtKB=A0A3B6U0A4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G386000\|UniProtKB=A0A3B6MX64	Triticum aestivum	O
NELNU\|Gene_ORFName=HUJ06_001800\|UniProtKB=A0A1U8A1Q1	Nelumbo nucifera	O
HELAN\|EnsemblGenome=HanXRQr2_Chr04g0179001\|UniProtKB=A0A251V3G5	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C700354930\|UniProtKB=A0A9R1UY69	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a013530mg\|UniProtKB=A0A022RTX7	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_04981\|UniProtKB=A0A2G3A6M7	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400021197\|UniProtKB=M1BWM2	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc02g069680.3\|UniProtKB=A0A3Q7F1H1	Solanum lycopersicum	O
TOBAC\|Gene=LOC107797121\|UniProtKB=A0A1S4AFR2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107784069\|UniProtKB=A0A1S3Z8U4	Nicotiana tabacum	O
VITVI\|Gene_OrderedLocusName=VIT_10s0092g00360\|UniProtKB=D7U8F6	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_D01033\|UniProtKB=A0A059CFE9	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_A08P14760.1\|UniProtKB=A0A078H0Y0	Brassica napus	O
BRACM\|EnsemblGenome=Bra013459\|UniProtKB=M4DAE9	Brassica campestris	O
BRACM\|EnsemblGenome=Bra020925\|UniProtKB=M4DWN1	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A06P47090.1\|UniProtKB=A0A078IGB5	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_C07P27450.1\|UniProtKB=A0A078IKB3	Brassica napus	O
BRACM\|EnsemblGenome=Bra033752\|UniProtKB=M4EY61	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00070945001\|UniProtKB=A0A078FFF5	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00041889001\|UniProtKB=A0A078GUB3	Brassica napus	O
BRACM\|EnsemblGenome=Bra027559\|UniProtKB=M4EFJ7	Brassica campestris	O
ARATH\|TAIR=locus=2163396\|UniProtKB=Q0WTY4	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107957741\|UniProtKB=A0A1U8PET3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107925159\|UniProtKB=A0A1U8L9G2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107930312\|UniProtKB=A0A1U8LW11	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_026946\|UniProtKB=A0A061G8S8	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g026014mg\|UniProtKB=A0A067GFW1	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_001G442500v3\|UniProtKB=A0A2K2CD39	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_011G154700v3\|UniProtKB=A0A2K1YKV3	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_16G062300\|UniProtKB=A0A2C9U9F1	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0770230\|UniProtKB=B9SV62	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_15G192100\|UniProtKB=I1MHS1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_09G083700\|UniProtKB=I1L219	Glycine max	O
MEDTR\|EnsemblGenome=MTR_2g047875\|UniProtKB=B7FHD8	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr03_18030\|UniProtKB=A0A2I4FA45	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_6G526330\|UniProtKB=A0A0A0KL14	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_4G103400\|UniProtKB=A0A251PIE6	Prunus persica	O
ZOSMR\|Gene_ORFName=ZOSMA_122G00840\|UniProtKB=A0A0K9Q0J7	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma05_g03640\|UniProtKB=A0A804J0I3	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_037480mg\|UniProtKB=K4AF23	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G220400\|UniProtKB=C5WYG6	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb045910\|UniProtKB=B6T5E0	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os10g0476400\|UniProtKB=Q9AUZ6	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g28730v3\|UniProtKB=I1I4N7	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0042770\|UniProtKB=F2DWE7	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1A02G153600\|UniProtKB=A0A3B5XYA3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G152000\|UniProtKB=A0A3B5ZSP1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1B02G171400\|UniProtKB=A0A3B5YWL4	Triticum aestivum	LDO
NELNU\|Gene=LOC104602851\|UniProtKB=A0A1U8AGX9	Nelumbo nucifera	LDO
NELNU\|Gene=LOC104600906\|UniProtKB=A0A1U8A747	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110794417\|UniProtKB=A0A9R0IT28	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0250021\|UniProtKB=A0A251UHJ6	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C800425450\|UniProtKB=A0A9R1UUH9	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a023516mg\|UniProtKB=A0A022S513	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a013718mg\|UniProtKB=A0A022PR45	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_17475\|UniProtKB=A0A2G2ZBP1	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_15804\|UniProtKB=A0A1U8H4S1	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400014701\|UniProtKB=M1B6C8	Solanum tuberosum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400031445\|UniProtKB=M1D3W9	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc06g008290.3\|UniProtKB=A0A3Q7GMW6	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107772636\|UniProtKB=A0A1S3Y6A2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107794710\|UniProtKB=A0A1S4A7V0	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi07g00629\|UniProtKB=D7U324	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_B01559\|UniProtKB=A0A059D2U1	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C05P02280.1\|UniProtKB=A0A078FYU3	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra015280\|UniProtKB=A0A397XHR1	Brassica campestris	LDO
ARATH\|TAIR=locus=2024107\|UniProtKB=Q941D5	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107958637\|UniProtKB=A0A1U8PIB4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107955524\|UniProtKB=A0A1U8P6F6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107952890\|UniProtKB=A0A1U8P044	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_003980\|UniProtKB=A0A061DPN9	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g028201mg\|UniProtKB=A0A067EZA4	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_002G035900v3\|UniProtKB=B9GRN7	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_12G034200\|UniProtKB=A0A2C9UV67	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_13G036100\|UniProtKB=A0A2C9UNB4	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0259430\|UniProtKB=B9SV23	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_03G164800\|UniProtKB=I1JP52	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_19G166200\|UniProtKB=I1N9S5	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_7g097170\|UniProtKB=A0A072U3L4	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr01_32450\|UniProtKB=A0A2I4F6I5	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G372290\|UniProtKB=A0A0A0K5C0	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_8G220500\|UniProtKB=A0A251N1K3	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_130018\|UniProtKB=D8T1U8	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_228468\|UniProtKB=D8S2P9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_441725\|UniProtKB=D8RLA7	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_266789\|UniProtKB=D8R0E6	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c3_2240\|UniProtKB=A0A2K1KSY1	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c13_6090\|UniProtKB=A0A2K1JLF7	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c23_14890\|UniProtKB=A0A2K1IJE9	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0136s0022\|UniProtKB=A0A2R6W765	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001470110\|UniProtKB=A0A1Y1HXM8	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0029\|UniProtKB=A9A520	Nitrosopumilus maritimus	O
SACS2\|EnsemblGenome=SSO0910\|UniProtKB=Q97ZJ6	Sulfolobus solfataricus	O