PANTHER Gene Information

Gene Symbol(s):

DmelCG4880

Organism:

Drosophila melanogaster

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Gene Name:

LD13476p

Gene ID:

FBgn0030803

Protein ID:

Q9VX97

Persistent Id:

PTN002243420

Alternate Ids:

Q9VX97_DROME(UniProtKB-ID)	FBtr0074342(Ensembl_TRS)
162944852(GI)	NP_573177(refSeq)
AAO25025(EMBL-CDS)	FBgn0030803(Ensembl)
Q9VX97(Synonym)	AE014298(EMBL)
FBgn0030803(FlyBase)	FBpp0074116(Ensembl_PRO)
32680(GeneID)
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PANTHER Classification

PANTHER Family:	TORSIN (PTHR10760)
PANTHER Subfamily:	LD13476P-RELATED (PTHR10760:SF2)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	chaperone

Pathway Categories:

Parkinson disease

Torsin A

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP hydrolysis activity, ATP binding
GO BP Complete:	cellular response to misfolded protein
GO CC Complete:	-

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Response to elevated platelet cytosolic Ca2+, Clathrin-mediated endocytosis, Platelet degranulation , Hemostasis, Membrane Trafficking, Platelet activation, signaling and aggregation, Vesicle-mediated transport, Cargo recognition for clathrin-mediated endocytosis

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11996\|UniProtKB=Q5JU69	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000021396.6\|UniProtKB=H2QXX6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011044.3\|UniProtKB=G3R628	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000016429.4\|UniProtKB=H9FT45	Macaca mulatta	O
MOUSE\|MGI=MGI=1353596\|UniProtKB=Q8R1J9	Mus musculus	O
RAT\|RGD=1359111\|UniProtKB=Q6AYR4	Rattus norvegicus	O
BOVIN\|Gene=TOR2A\|UniProtKB=P0C7W1	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000013510\|UniProtKB=A4FUH1	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000005619.5\|UniProtKB=F1RS09	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014482.4\|UniProtKB=A0A9L0RU30	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000046339.2\|UniProtKB=M3WVJ5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845005640.1\|UniProtKB=A0A8I3MRM3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000005518.4\|UniProtKB=F7G5K0	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000040414.1\|UniProtKB=A0A6I8PFT8	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010028096.1\|UniProtKB=A0A8V1AC68	Gallus gallus	O
XENLA\|Gene=LOC108709579\|UniProtKB=A0A1L8H7S4	Xenopus laevis	O
XENLA\|Gene=tor2a\|UniProtKB=Q68F68	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5806617\|UniProtKB=Q28G83	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000020659.2\|UniProtKB=H2N2B0	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-050913-60\|UniProtKB=Q4V8W5	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002778.1\|UniProtKB=W5M4G1	lepisosteus oculatus	O
HUMAN\|HGNC=25981\|UniProtKB=Q9NXH8	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000048359.1\|UniProtKB=H2R2W6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000044182.1\|UniProtKB=A0A2I2ZKQ3	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000004943.3\|UniProtKB=F7C872	Macaca mulatta	O
MOUSE\|MGI=MGI=2442720\|UniProtKB=Q8BH02	Mus musculus	O
RAT\|RGD=1308019\|UniProtKB=D3ZG57	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000023787.4\|UniProtKB=G3X7J5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000005845.5\|UniProtKB=F1RVY0	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000017501.3\|UniProtKB=F6PKC7	Equus caballus	O
MONDO\|Ensembl=ENSMODG00000017221.4\|UniProtKB=F6WXT3	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000039427.1\|UniProtKB=A0A6I8PFR4	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010027896.1\|UniProtKB=F1NLT2	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000038715.1\|UniProtKB=A0A803TBU9	Anolis carolinensis	O
XENLA\|Gene=tor4a.L\|UniProtKB=A0A1L8F5N1	Xenopus laevis	O
XENLA\|Gene=tor4a-b\|UniProtKB=Q3KQ18	Xenopus laevis	O
XENLA\|Gene=tor4a-a\|UniProtKB=Q0IHC5	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-975360\|UniProtKB=Q5BKJ7	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000000532.2\|UniProtKB=H2L4F9	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-070705-135\|UniProtKB=A7MBW1	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050417-9\|UniProtKB=Q568B8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000017339.1\|UniProtKB=W5NLD5	lepisosteus oculatus	O
HUMAN\|HGNC=11997\|UniProtKB=Q9H497	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000001726.7\|UniProtKB=A0A2I3RAV2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002627.3\|UniProtKB=A0A2I2ZGQ9	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000006261.4\|UniProtKB=F7H528	Macaca mulatta	O
MOUSE\|MGI=MGI=1353652\|UniProtKB=Q9ER38	Mus musculus	O
RAT\|RGD=1310101\|UniProtKB=Q5M936	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000014006.5\|UniProtKB=A1A4M8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000015525.5\|UniProtKB=F1S6A3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000017956.4\|UniProtKB=A0A9L0R3Y3	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005304.6\|UniProtKB=M3W3U5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845006652.1\|UniProtKB=A0A8I3N1V9	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000006073.4\|UniProtKB=F7FEZ8	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000005638.2\|UniProtKB=F7AGI3	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010011055.1\|UniProtKB=A0A8V0Y9I2	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000012264.4\|UniProtKB=H9GIQ8	Anolis carolinensis	O
XENLA\|Gene=tor3a.L\|UniProtKB=A0A1L8GMP8	Xenopus laevis	O
ORYLA\|Ensembl=ENSORLG00000017174.2\|UniProtKB=H2MRV5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-081104-165\|UniProtKB=A9C3S4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009789.1\|UniProtKB=W5MUA9	lepisosteus oculatus	O
HUMAN\|HGNC=11995\|UniProtKB=O14657	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000023109.5\|UniProtKB=H2R1X1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000013351.3\|UniProtKB=G3RC05	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000003793.4\|UniProtKB=H9ESY7	Macaca mulatta	O
MOUSE\|MGI=MGI=1353605\|UniProtKB=Q9ER41	Mus musculus	O
RAT\|RGD=1308431\|UniProtKB=Q2M2S1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000002837.6\|UniProtKB=F1MBM5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000005683.5\|UniProtKB=A0A8W4F936	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000008630.3\|UniProtKB=F6WGK1	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000008977.6\|UniProtKB=M3WAK2	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845023333.1\|UniProtKB=A0A8I3PE10	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000006789.4\|UniProtKB=F6PH52	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000002550.3\|UniProtKB=F7FLM6	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010028491.1\|UniProtKB=A0A1L1RTK2	Gallus gallus	O
HUMAN\|HGNC=3098\|UniProtKB=O14656	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000022599.4\|UniProtKB=H2QZU6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000013356.3\|UniProtKB=G3RC08	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000058799.1\|UniProtKB=F7GVG2	Macaca mulatta	O
MOUSE\|MGI=MGI=1353568\|UniProtKB=Q9ER39	Mus musculus	O
RAT\|RGD=628863\|UniProtKB=Q68G38	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000020305.5\|UniProtKB=A5PK75	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000034518.3\|UniProtKB=A7YX22	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000013990.3\|UniProtKB=F7APJ8	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000004760.6\|UniProtKB=M3W2T0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845023305.1\|UniProtKB=A0A8I3PV70	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000006810.5\|UniProtKB=F6PGK6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000037291.1\|UniProtKB=F7FLM1	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010028489.1\|UniProtKB=A0A8V1AGK6	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010028493.1\|UniProtKB=A0A8V1A8Z2	Gallus gallus	O
XENLA\|Gene=tor1a.L\|UniProtKB=Q6AZG2	Xenopus laevis	O
XENLA\|Gene=tor1a.S\|UniProtKB=A0A1L8F1E5	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-943837\|UniProtKB=Q28CP8	Xenopus tropicalis	O
XENLA\|Gene=tor1b.L\|UniProtKB=A0A8J0TXI0	Xenopus laevis	O
XENLA\|Gene=LOC108704465\|UniProtKB=A0A8J1LJL1	Xenopus laevis	O
XENLA\|Gene=tor1b.2.L\|UniProtKB=A0A8J1LJK0	Xenopus laevis	O
XENLA\|Gene=LOC108699946\|UniProtKB=A0A1L8F1I5	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-986914\|UniProtKB=Q28CA4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000003403.2\|UniProtKB=H2LE64	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-121107-3\|UniProtKB=E7FDJ9	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-040426-1859\|UniProtKB=Q6P5L4	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-080723-36\|UniProtKB=B3DJX5	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-080917-50\|UniProtKB=E9QG29	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000003627.1\|UniProtKB=W5M7E8	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000023107.1\|UniProtKB=H2XLI1	Ciona intestinalis	O
BRAFL\|Gene=LOC118421275\|UniProtKB=A0A9J7MZK0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118404402\|UniProtKB=A0A9J7HGS7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420993\|UniProtKB=A0A9J7MZ01	Branchiostoma floridae	O
BRAFL\|Gene=LOC118420613\|UniProtKB=A0A9J7LI37	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_128102\|UniProtKB=C3Z7Y3	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC115926202\|UniProtKB=A0A7M7P6W3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC753283\|UniProtKB=A0A7M7P5K9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC575885\|UniProtKB=A0A7M7P5Q6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446497\|UniProtKB=A0A7M7T4T6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100892342\|UniProtKB=A0A7M7T4I6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592199\|UniProtKB=A0A7M7PR66	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC577447\|UniProtKB=A0A7M7RCT9	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00006598\|UniProtKB=Q9XXG5	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00006597\|UniProtKB=O45271	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00003870\|UniProtKB=Q95NU5	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG21284\|UniProtKB=A8XZR7	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG03231\|UniProtKB=A8WSH7	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00114552\|UniProtKB=A0A2A6CF20	Pristionchus pacificus	O
ANOGA\|EnsemblGenome=AGAP029921\|UniProtKB=A0A903XZ27	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC000824\|UniProtKB=D6W8J5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_103087\|UniProtKB=E9GIC9	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_129381\|UniProtKB=E9H4U5	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW017089\|UniProtKB=B7PA07	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW017088\|UniProtKB=B7PA06	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG176967\|UniProtKB=T1FB29	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG86403\|UniProtKB=T1G6B7	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g221156\|UniProtKB=A7T210	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g200001\|UniProtKB=A7RP69	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g142536\|UniProtKB=A7T211	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g241618\|UniProtKB=A7RYS7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g98049\|UniProtKB=A7RYS5	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG58752\|UniProtKB=B3S3K1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG33759\|UniProtKB=B3SD48	Trichoplax adhaerens	O
DICDI\|dictyBase=DDB_G0268156\|UniProtKB=Q55FE2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_95750\|UniProtKB=F1A0B2	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_09_0820\|UniProtKB=Q4QHU2	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.52.0010\|UniProtKB=Q382P2	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_24_2220\|UniProtKB=Q4QAA8	Leishmania major	O
TRYB2\|Gene_ORFName=Tb927.8.6020\|UniProtKB=Q57YK3	Trypanosoma brucei	O
PHYRM\|Gene=H3GE23_PHYRM\|UniProtKB=H3GE23	Phytophthora ramorum	O
PHYRM\|Gene=H3GDH8_PHYRM\|UniProtKB=H3GDH8	Phytophthora ramorum	O
PHYRM\|Gene=H3HAG1_PHYRM\|UniProtKB=H3HAG1	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_10g443801v5\|UniProtKB=A0A2K3DAP1	Chlamydomonas reinhardtii	O