PANTHER Gene Information

Gene Symbol(s):

Nadsyn

Organism:

Drosophila melanogaster

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Gene Name:

Glutamine-dependent NAD(+) synthetase

Gene ID:

FBgn0030512

Protein ID:

Q9VYA0

Persistent Id:

PTN000558011

Alternate Ids:

Nadsyn{ECO:0000312\|FlyBase:FBgn0030512}(Symbol)	NAD(+) synthase [glutamine-hydrolyzing](Synonym)
FBgn0030512(FlyBase)	FBtr0073845(Ensembl_TRS)
NP_001285224(refSeq)	FBpp0073676(Ensembl_PRO)
FBgn0030512(Ensembl)	8928236(GI)
6.3.5.1 {ECO:0000250\|UniProtKB:Q6IA69}(EC)	AAN09333(EMBL-CDS)
A4V4E7(AltAccession)	BT001474(EMBL)
NADE_DROME(UniProtKB-ID)	32328(GeneID)
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PANTHER Classification

PANTHER Family:	NH 3 /GLUTAMINE-DEPENDENT NAD + SYNTHETASE (PTHR23090)
PANTHER Subfamily:	GLUTAMINE-DEPENDENT NAD(+) SYNTHETASE (PTHR23090:SF9)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	nicotinamide nucleotide metabolic process purine nucleotide biosynthetic process
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	glutaminase activity, NAD+ synthase (glutamine-hydrolyzing) activity, ATP binding
GO BP Complete:	negative regulation of neuromuscular synaptic transmission, NAD biosynthetic process
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Metabolism of vitamins and cofactors, Metabolism, Nicotinate metabolism, Metabolism of water-soluble vitamins and cofactors

Orthologs

ID	Organism	Type
HUMAN\|HGNC=29832\|UniProtKB=Q6IA69	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004014.5\|UniProtKB=A0A2I3RZ54	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000006551.3\|UniProtKB=G3RX01	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011977.4\|UniProtKB=A0A5F7ZW03	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1926164\|UniProtKB=Q711T7	Mus musculus	LDO
RAT\|RGD=727801\|UniProtKB=Q812E8	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000016470\|UniProtKB=Q3ZBF0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000012859.5\|UniProtKB=A0A480X661	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000023476.3\|UniProtKB=A0A9L0SXH4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000004116.6\|UniProtKB=M3W1L6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845012869.1\|UniProtKB=A0A8I3NRA5	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000007384.4\|UniProtKB=F7G4Y5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000011297.4\|UniProtKB=A0A6I8N6F3	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010020987.1\|UniProtKB=A0A8V0Z9K3	Gallus gallus	LDO
CHICK\|Gene_ORFName=RCJMB04_2l1\|UniProtKB=Q5ZMA6	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000015847.3\|UniProtKB=G1KRU6	Anolis carolinensis	LDO
XENLA\|Gene=nadsyn1.L\|UniProtKB=A0A1L8GIT4	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-971835\|UniProtKB=A0A803KL75	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000019547.2\|UniProtKB=H2MZ43	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070615-22\|UniProtKB=A5PLA8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005029.1\|UniProtKB=W5MCF0	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008813.3\|UniProtKB=F7BJC2	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118406740\|UniProtKB=A0A9J7KAB4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115924960\|UniProtKB=A0A7M7P4R5	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC575432\|UniProtKB=A0A7M7NZN5	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00007698\|UniProtKB=Q9XXK6	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00026262\|UniProtKB=A8WUY2	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00092814\|UniProtKB=A0A8R1U5L3	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP000112\|UniProtKB=Q7PS02	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC007403\|UniProtKB=D1ZZT1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_196799\|UniProtKB=E9GIU1	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW004036\|UniProtKB=B7PJF6	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG191543\|UniProtKB=T1FT24	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g173435\|UniProtKB=A7SR86	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG54321\|UniProtKB=B3RRQ0	Trichoplax adhaerens	LDO
YEAST\|SGD=S000001116\|UniProtKB=P38795	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AGR358W\|UniProtKB=Q74Z48	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000191648\|UniProtKB=Q5ALW6	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_A20108g\|UniProtKB=Q6CGE0	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_08203\|UniProtKB=Q5AU27	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G03350\|UniProtKB=Q4WEK7	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU04648\|UniProtKB=V5INQ7	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_13042\|UniProtKB=A7F614	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_06281\|UniProtKB=Q0UPN3	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPCC553.02\|UniProtKB=O74940	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_02618\|UniProtKB=B6K0Q9	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNK02550\|UniProtKB=Q5K9B2	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_03555\|UniProtKB=A0A0D1CPD0	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_00406\|UniProtKB=E3JRH7	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_33585\|UniProtKB=F4P9B7	Batrachochytrium dendrobatidis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_17496\|UniProtKB=F4P9H6	Batrachochytrium dendrobatidis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_31001\|UniProtKB=F4PG14	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_134830\|UniProtKB=C4M032	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0285877\|UniProtKB=Q54ML1	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_56621\|UniProtKB=F0ZSB7	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_32_1670\|UniProtKB=Q4Q5B3	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.6500\|UniProtKB=Q381U8	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_31530\|UniProtKB=A8BSZ5	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_188330\|UniProtKB=A2DV55	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0926700\|UniProtKB=Q8I2P2	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00009199001\|UniProtKB=A0CPU0	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00017670001\|UniProtKB=A0DJV9	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPS_269255\|UniProtKB=B5YN79	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G891_PHYRM\|UniProtKB=H3G891	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_10g435250v5\|UniProtKB=C4PG67	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00092p00062310\|UniProtKB=W1NQJ1	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_8G00780\|UniProtKB=A0A0K9NJY8	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma02_g07730\|UniProtKB=A0A804I0C9	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_029058mg\|UniProtKB=K3ZR28	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G112700\|UniProtKB=C5X4A1	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb094700\|UniProtKB=A0A1D6EKN5	Zea mays	LDO
ORYSJ\|Gene_OrderedLocusName=LOC_Os07g07260\|UniProtKB=Q0D8D4	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g29020v3\|UniProtKB=I1GUX2	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0231010\|UniProtKB=F2D7Y8	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3A02G076400\|UniProtKB=A0A3B6EAV5	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS3D02G076500\|UniProtKB=A0A3B6GR35	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3B02G090300\|UniProtKB=W5CPG8	Triticum aestivum	LDO
NELNU\|Gene=LOC104588790\|UniProtKB=A0A1U7YZT4	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110803425\|UniProtKB=A0A9R0KAF4	Spinacia oleracea	O
SPIOL\|Gene=LOC110803419\|UniProtKB=A0A9R0JDQ3	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0241831\|UniProtKB=A0A251UFZ3	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr03g0128681\|UniProtKB=A0A251V971	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600330020\|UniProtKB=A0A9R1VBZ7	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a0019881mg\|UniProtKB=A0A022R3X0	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_00062\|UniProtKB=A0A1U8G2C1	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400012128\|UniProtKB=M1AVY1	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc08g082840.2\|UniProtKB=A0A3Q7HV55	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107805431\|UniProtKB=A0A1S4B7N3	Nicotiana tabacum	O
TOBAC\|Gene=LOC107828249\|UniProtKB=A0A1S4DC58	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi02g00188\|UniProtKB=D7TVM2	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_E01025\|UniProtKB=A0A059C300	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C03P92220.1\|UniProtKB=A0A078F832	Brassica napus	O
BRACM\|EnsemblGenome=Bra030888\|UniProtKB=M4EQ17	Brassica campestris	O
BRANA\|EnsemblGenome=GSBRNA2T00087008001\|UniProtKB=A0A078JUU4	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00024587001\|UniProtKB=A0A078GFB6	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra037978\|UniProtKB=M4FA64	Brassica campestris	LDO
ARATH\|TAIR=locus=2205667\|UniProtKB=Q9C723	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107911417\|UniProtKB=A0A1U8K192	Gossypium hirsutum	O
GOSHI\|Gene=LOC107946869\|UniProtKB=A0A1U8NCW4	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_016517\|UniProtKB=A0A061G6R3	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g0095372mg\|UniProtKB=A0A067F8T0	Citrus sinensis	LDO
CITSI\|Gene_ORFName=CISIN_1g004727mg\|UniProtKB=A0A067GDC2	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_003G143700v3\|UniProtKB=B9GXU1	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_001G087400v3\|UniProtKB=B9GL17	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G005800\|UniProtKB=A0A251LDH0	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_1312520\|UniProtKB=B9RYQ0	Ricinus communis	O
MANES\|EnsemblGenome=MANES_02G005900\|UniProtKB=A0A2C9W9N8	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1312290\|UniProtKB=B9RYP7	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_08G025800\|UniProtKB=I1KPN4	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_05G219500\|UniProtKB=I1K669	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_8g099885\|UniProtKB=A0A072U616	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr02_15580\|UniProtKB=A0A2I4FU75	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G149340\|UniProtKB=A0A0A0KMF0	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G126000\|UniProtKB=M5WFK3	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_166255\|UniProtKB=D8QWX6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_125463\|UniProtKB=D8SV54	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_95570\|UniProtKB=D8RL09	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_267968\|UniProtKB=D8RZ09	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c17_21910\|UniProtKB=A0A7I4F888	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0035s0052\|UniProtKB=A0A2R6X573	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_002540060\|UniProtKB=A0A1Y1I764	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_0966\|UniProtKB=A9A2F1	Nitrosopumilus maritimus	LDO
KORCO\|EnsemblGenome=Kcr_0978\|UniProtKB=B1L5J5	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO2172\|UniProtKB=Q97WN9	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE1219\|UniProtKB=Q8ZXL4	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_3715\|UniProtKB=Q8TJR4	Methanosarcina acetivorans	O
METAC\|EnsemblGenome=MA_1030\|UniProtKB=Q8TRY1	Methanosarcina acetivorans	O
METAC\|EnsemblGenome=MA_3526\|UniProtKB=Q8TK88	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_1352\|UniProtKB=Q58747	Methanocaldococcus jannaschii	LDO
THEKO\|EnsemblGenome=TK1798\|UniProtKB=Q5JJ65	Thermococcus kodakaraensis	LDO
STRCO\|Gene_OrderedLocusName=SCO0506\|UniProtKB=Q9RJM5	Streptomyces coelicolor	O
STRR6\|EnsemblGenome=spr1276\|UniProtKB=P65509	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_02132\|UniProtKB=Q2G236	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAC99171\|UniProtKB=Q8Y825	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_03130\|UniProtKB=P08164	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_1994\|UniProtKB=Q81EI2	Bacillus cereus	O
DEIRA\|EnsemblGenome=DR_A0201\|UniProtKB=Q9RYV5	Deinococcus radiodurans	O
SHEON\|Gene_OrderedLocusName=SO_2021\|UniProtKB=Q8EFF2	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_A0207\|UniProtKB=Q9KMW1	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA4920\|UniProtKB=Q9HUP3	Pseudomonas aeruginosa	O
CHLAA\|EnsemblGenome=Caur_1374\|UniProtKB=A9W9W6	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO2238\|UniProtKB=Q9ADI8	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv2438c\|UniProtKB=P9WJJ3	Mycobacterium tuberculosis	LDO
CLOBH\|Gene_OrderedLocusName=CBO0537\|UniProtKB=A5HZ81	Clostridium botulinum	LDO
THEMA\|EnsemblGenome=TM_0645\|UniProtKB=Q9WZB3	Thermotoga maritima	O
THEMA\|EnsemblGenome=TM_1253\|UniProtKB=Q9X0Y0	Thermotoga maritima	LDO
GLOVI\|Gene=nadE\|UniProtKB=Q7NHF0	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA18386\|UniProtKB=P74292	Synechocystis	LDO
BACTN\|EnsemblGenome=BT_0205\|UniProtKB=Q8ABA5	Bacteroides thetaiotaomicron	LDO
RHOBA\|EnsemblGenome=RB5671\|UniProtKB=Q7URG9	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_959\|UniProtKB=O67091	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A0448\|UniProtKB=B5YJ78	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_0182\|UniProtKB=B8E1I6	Dictyoglomus turgidum	LDO
FUSNN\|EnsemblGenome=FN1202\|UniProtKB=Q8REA7	Fusobacterium nucleatum	LDO
GEOSL\|EnsemblGenome=GSU0652\|UniProtKB=Q74FF7	Geobacter sulfurreducens	LDO
BRADU\|Gene=nadE\|UniProtKB=Q89NQ4	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_0858\|UniProtKB=Q83D82	Coxiella burnetii	LDO
XANCP\|EnsemblGenome=XCC3091\|UniProtKB=Q8P679	Xanthomonas campestris	LDO
YERPE\|Gene_OrderedLocusName=YPO2912\|UniProtKB=A0A3N4AYX8	Yersinia pestis	LDO