PANTHER Gene Information

Gene Symbol(s):

PTP-ER

Organism:

Drosophila melanogaster

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Gene Name:

Protein tyrosine phosphatase ERK

Gene ID:

FBgn0016641

Protein ID:

Q9W2F3

Persistent Id:

PTN000440262

Alternate Ids:

37461(GeneID)	21645298(GI)
Q9W2F3(Synonym)	FBtr0071686(Ensembl_TRS)
NP_726092(refSeq)	AE013599(EMBL)
FBgn0016641(FlyBase)	Q9W2F3_DROME(UniProtKB-ID)
AAD38688(EMBL-CDS)	FBpp0071603(Ensembl_PRO)
FBgn0016641(Ensembl)
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PANTHER Classification

PANTHER Family:	RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE (PTHR19134)
PANTHER Subfamily:	TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 7 (PTHR19134:SF527)
PANTHER GO-slim Molecular Function:	protein tyrosine phosphatase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	protein phosphatase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	MAP kinase phosphatase activity, non-membrane spanning protein tyrosine phosphatase activity, protein tyrosine phosphatase activity
GO BP Complete:	signal transduction, negative regulation of ERK1 and ERK2 cascade, protein dephosphorylation, mitotic cell cycle
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

MAPK1/MAPK3 signaling, MAPK family signaling cascades, RAF/MAP kinase cascade, Signal Transduction, Negative regulation of MAPK pathway

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9659\|UniProtKB=P35236	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001848.6\|UniProtKB=H2Q0W8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000016520.3\|UniProtKB=G3RK58	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000013789.4\|UniProtKB=F6TEC2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2156893\|UniProtKB=Q8BUM3	Mus musculus	LDO
RAT\|RGD=708516\|UniProtKB=P49445	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000003016.5\|UniProtKB=A0A3Q1MNB6	Bos taurus	LDO
MONDO\|Ensembl=ENSMODG00000000597.4\|UniProtKB=F6TBG1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000012567.3\|UniProtKB=A0A6I8N4G2	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000004209.4\|UniProtKB=G1KCS2	Anolis carolinensis	LDO
CIOIN\|Ensembl=ENSCING00000001184.3\|UniProtKB=F6WAH3	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000017017.2\|UniProtKB=F7A0I1	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000010806.3\|UniProtKB=F6WY52	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000008175.3\|UniProtKB=F6PP55	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000002801.3\|UniProtKB=F6XMR8	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000017997.1\|UniProtKB=H2XU36	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000000420.3\|UniProtKB=H2Y1M2	Ciona intestinalis	LDO
CAEEL\|WormBase=WBGene00020035\|UniProtKB=O61789	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00020652\|UniProtKB=O01767	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00033058\|UniProtKB=A8XEF5	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00098146\|UniProtKB=A0A2A6BLI9	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096893\|UniProtKB=A0A2A6C7L7	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP007118\|UniProtKB=A0A1S4GU65	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015377\|UniProtKB=D2A4J3	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW017704\|UniProtKB=B7PIM6	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g123777\|UniProtKB=A7SMI6	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g160028\|UniProtKB=A7RL98	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g35794\|UniProtKB=A7RL95	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g41992\|UniProtKB=A7T229	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g10792\|UniProtKB=A7SWW8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246683\|UniProtKB=A7SQ18	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g123758\|UniProtKB=A7SMI4	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG57823\|UniProtKB=B3S1N2	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_26140\|UniProtKB=A9V1H0	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_38140\|UniProtKB=A9V5X4	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_38569\|UniProtKB=A9V8T4	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_38116\|UniProtKB=A9V5S7	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_36156\|UniProtKB=A9UTF3	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_25910\|UniProtKB=A9V0U1	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_2433\|UniProtKB=A9UXB5	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_26361\|UniProtKB=A9V253	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_8034\|UniProtKB=A9UYU9	Monosiga brevicollis	O
YEAST\|SGD=S000002389\|UniProtKB=P25044	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_ABL172C\|UniProtKB=Q75E42	Eremothecium gossypii	O
CANAL\|CGD=CAL0000179853\|UniProtKB=Q5A399	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_F30943g\|UniProtKB=Q6BZT9	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_04896\|UniProtKB=C8V9H4	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_3G10970\|UniProtKB=Q4WXW9	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02257\|UniProtKB=Q7S5A7	Neurospora crassa	O
SCLS1\|Gene_ORFName=SS1G_07944\|UniProtKB=A7ERJ0	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_12091\|UniProtKB=Q0U823	Phaeosphaeria nodorum	O
SCLS1\|EnsemblGenome=SS1G_03598\|UniProtKB=A7EE58	Sclerotinia sclerotiorum	O
SCHPO\|PomBase=SPAC19D5.01\|UniProtKB=P32586	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_02000\|UniProtKB=B6JZG2	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPAC26F1.10c\|UniProtKB=P27574	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_02013\|UniProtKB=B6JZH3	Schizosaccharomyces japonicus	O
SCHPO\|PomBase=SPAC11E3.09\|UniProtKB=P32587	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_00214\|UniProtKB=B6JV14	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNM00730\|UniProtKB=Q5K7Z6	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_05679\|UniProtKB=A0A0D1DR65	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_10786\|UniProtKB=E3KK02	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_24597\|UniProtKB=F4P1T7	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=CL6EHI_024450\|UniProtKB=C4M0I7	Entamoeba histolytica	O
ENTH1\|Gene_ORFName=EHI_049430\|UniProtKB=A0A8U0WQ14	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0273097\|UniProtKB=P34137	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_43829\|UniProtKB=F1A4W4	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0282145\|UniProtKB=P54637	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_99148\|UniProtKB=F0ZWP2	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0277865\|UniProtKB=P34138	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_92527\|UniProtKB=F0ZTB9	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_36_2180\|UniProtKB=Q4Q1K3	Leishmania major	O
TRYB2\|Gene_ORFName=Tb10.70.0070\|UniProtKB=Q38AT7	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_36_5370\|UniProtKB=Q4Q0M4	Leishmania major	O
GIAIC\|EnsemblGenome=GL50803_25035\|UniProtKB=A8B908	Giardia intestinalis	O
PARTE\|EnsemblGenome=GSPATT00019518001\|UniProtKB=A0DRZ7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00038739001\|UniProtKB=A0CMV5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00031165001\|UniProtKB=A0BQW9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00029051001\|UniProtKB=A0BHJ9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018178001\|UniProtKB=A0DLE4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00039454001\|UniProtKB=A0DEA3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00028520001\|UniProtKB=A0BG18	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00010702001\|UniProtKB=A0CUN5	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00012530001\|UniProtKB=A0D1T8	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035547001\|UniProtKB=A0C6K1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036162001\|UniProtKB=A0C8B3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00034588001\|UniProtKB=A0C2U3	Paramecium tetraurelia	O
CHLRE\|EnsemblGenome=CHLRE_09g389949v5\|UniProtKB=A0A2K3DE23	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g524450v5\|UniProtKB=A0A2K3D4B0	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00247p00015290\|UniProtKB=W1NPI4	Amborella trichopoda	O
MUSAM\|EnsemblGenome=Ma06_g14480\|UniProtKB=A0A804JG76	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma03_g02730\|UniProtKB=A0A804I7S2	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_026715mg\|UniProtKB=K3ZJG2	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3005G061801\|UniProtKB=A0A1Z5RHV4	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb091350\|UniProtKB=A0A1D6EHC5	Zea mays	O
BRADI\|EnsemblGenome=BRADI_4g24017v3\|UniProtKB=A0A2K2CPW3	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_4g24006v3\|UniProtKB=A0A2K2CPZ2	Brachypodium distachyon	O
WHEAT\|EnsemblGenome=TraesCS4D02G092700\|UniProtKB=A0A3B6JFZ3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4B02G096200\|UniProtKB=A0A3B6IN43	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS4A02G217600\|UniProtKB=A0A3B6HWM0	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_010288mg\|UniProtKB=K3Y7U4	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3008G055500\|UniProtKB=C5YSR9	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb138930\|UniProtKB=A0A804N6K7	Zea mays	O
ORYSJ\|EnsemblGenome=Os12g0174800\|UniProtKB=Q2QX07	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_4g41288v3\|UniProtKB=I1ITY7	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0135980\|UniProtKB=A0A8I6XFC0	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2B02G234600\|UniProtKB=A0A3B6C436	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G214800\|UniProtKB=A0A3B6DAA5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G208000\|UniProtKB=A0A3B6AVS6	Triticum aestivum	O
NELNU\|Gene=LOC104596727\|UniProtKB=A0A1U7ZQ54	Nelumbo nucifera	O
SPIOL\|Gene=LOC110788580\|UniProtKB=A0A9R0JVU3	Spinacia oleracea	O
SPIOL\|Gene=LOC110788500\|UniProtKB=A0A9R0IGN3	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0568091\|UniProtKB=A0A251SNK2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0568081\|UniProtKB=A0A251SMX8	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C500285840\|UniProtKB=A0A9R1VKZ8	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a009565mg\|UniProtKB=A0A022Q4E7	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a010376mg\|UniProtKB=A0A022Q9Q0	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_12149\|UniProtKB=A0A2G2ZNZ8	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc11g016990.2\|UniProtKB=A0A3Q7ISX4	Solanum lycopersicum	O
TOBAC\|Gene=LOC107803950\|UniProtKB=A0A1S4B364	Nicotiana tabacum	O
TOBAC\|Gene=LOC107793088\|UniProtKB=A0A1S4A2F4	Nicotiana tabacum	O
CAPAN\|EnsemblGenome=T459_17174\|UniProtKB=A0A2G2ZAU5	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400024543\|UniProtKB=M1CA19	Solanum tuberosum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400026120\|UniProtKB=M1CGU6	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc06g065480.3\|UniProtKB=A0A3Q7HS82	Solanum lycopersicum	O
TOBAC\|Gene=LOC107819053\|UniProtKB=A0A1S4CHD4	Nicotiana tabacum	O
VITVI\|Gene_OrderedLocusName=VIT_18s0076g00280\|UniProtKB=F6GYU9	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_F04145\|UniProtKB=A0A059BYJ9	Eucalyptus grandis	O
BRACM\|EnsemblGenome=Bra016108\|UniProtKB=M4DHY1	Brassica campestris	O
ARATH\|TAIR=locus=2012991\|UniProtKB=O82656	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107889363\|UniProtKB=A0A1U8HT91	Gossypium hirsutum	O
GOSHI\|Gene=LOC107891375\|UniProtKB=A0A1U8I7D3	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_036672\|UniProtKB=A0A061FSG8	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g019277mg\|UniProtKB=A0A067H890	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_019G086000v3\|UniProtKB=A0A2K1WRN7	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_013G115400v3\|UniProtKB=B9MW58	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_02G190000\|UniProtKB=A0A2C9WHM6	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_18G099100\|UniProtKB=A0A2C9U255	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0956930\|UniProtKB=B9T701	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_20G173700\|UniProtKB=K7N422	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_10G218100\|UniProtKB=I1LD92	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g096990\|UniProtKB=A0A072VNI9	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr15_07170\|UniProtKB=A0A2I4E6I9	Juglans regia	O
JUGRE\|EnsemblGenome=Jr06_09580\|UniProtKB=A0A2I4F125	Juglans regia	O
PRUPE\|EnsemblGenome=PRUPE_1G402600\|UniProtKB=A0A251RAI1	Prunus persica	O
PRUPE\|EnsemblGenome=PRUPE_8G052200\|UniProtKB=A0A251MWJ6	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_418145\|UniProtKB=D8S4T9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_409515\|UniProtKB=D8RBP9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_56201\|UniProtKB=D8S460	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_416055\|UniProtKB=D8RXX9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_410976\|UniProtKB=D8RHL7	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_66231\|UniProtKB=D8R6S8	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c13_6130\|UniProtKB=A0A2K1JKX2	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c3_2290\|UniProtKB=A0A2K1KSZ5	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0167s0026\|UniProtKB=A0A2R6W3B5	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_005550080\|UniProtKB=A0A1Y1IKQ0	Klebsormidium nitens	O