PANTHER Gene Information

Gene Symbol(s):

Rtel1

Organism:

Drosophila melanogaster

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Gene Name:

Regulator of telomere elongation helicase 1 homolog

Gene ID:

FBgn0029798

Protein ID:

Q9W484

Persistent Id:

PTN000158226

Alternate Ids:

Rtel1{ECO:0000303\|PubMed:34644293,ECO:0000312\|FlyBase:FBgn0029798}(Symbol)	BT021290(EMBL)
FBgn0029798(FlyBase)	FBpp0070773(Ensembl_PRO)
AAX33438(EMBL-CDS)	31497(GeneID)
A9YIW4(AltAccession)	RTEL1_DROME(UniProtKB-ID)
NP_572254(refSeq)	FBgn0029798(Ensembl)
3.6.4.12 {ECO:0000255\|HAMAP-Rule:MF_03065}(EC)	159152216(GI)
RTEL1(Synonym)	FBtr0332398(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER (PTHR11472)
PANTHER Subfamily:	REGULATOR OF TELOMERE ELONGATION HELICASE 1 (PTHR11472:SF34)
PANTHER GO-slim Molecular Function:	DNA helicase activity
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	DNA helicase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, ATP binding, DNA helicase activity, DNA polymerase binding, hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides, chromatin binding
GO BP Complete:	negative regulation of t-circle formation, DNA repair, telomeric loop disassembly, DNA replication, DNA duplex unwinding, male germ-line stem cell population maintenance, DNA recombination, telomere maintenance, regulation of double-strand break repair via homologous recombination, DNA damage response, negative regulation of DNA recombination
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000048787.1\|UniProtKB=A0A2I3TE43	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000042405.1\|UniProtKB=A0A2I2YK90	Gorilla gorilla gorilla	O
HUMAN\|HGNC=15888\|UniProtKB=Q9NZ71	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000052107.1\|UniProtKB=H2R359	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004784.3\|UniProtKB=G3RRM2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000167.4\|UniProtKB=F7HLR9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2139369\|UniProtKB=Q0VGM9	Mus musculus	LDO
RAT\|RGD=1306721\|UniProtKB=Q5RJZ1	Rattus norvegicus	LDO
BOVIN\|Gene=RTEL1\|UniProtKB=A4K436	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000021096.6\|UniProtKB=F1N079	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000039160.3\|UniProtKB=A0A287B3D4	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000021707.4\|UniProtKB=A0A9L0R4H3	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845017564.1\|UniProtKB=A0A8I3NU99	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017003.4\|UniProtKB=F6QF76	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000004935.4\|UniProtKB=F7E2C2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024973.1\|UniProtKB=A0A8V0ZVY2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000011739.4\|UniProtKB=A0A803SW31	Anolis carolinensis	LDO
XENLA\|Gene=rtel1.L\|UniProtKB=A0A8J0TVL1	Xenopus laevis	LDO
XENTR\|Gene=rtel1\|UniProtKB=A0A8J1IWY9	Xenopus tropicalis	LDO
DANRE\|ZFIN=ZDB-GENE-050306-11\|UniProtKB=P0C928	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001700.1\|UniProtKB=W5M0Q7	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118409403\|UniProtKB=A0A9J7HVW0	Branchiostoma floridae	LDO
CAEEL\|WormBase=WBGene00009124\|UniProtKB=Q93575	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00025337\|UniProtKB=A8WS58	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00113329\|UniProtKB=A0A8R1UHC1	Pristionchus pacificus	LDO
ANOGA\|EnsemblGenome=AGAP000634\|UniProtKB=Q7QEI1	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC007666\|UniProtKB=D2A2D4	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_128417\|UniProtKB=E9GJP0	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG79366\|UniProtKB=T1G3N2	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g168196\|UniProtKB=A7SA32	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG27892\|UniProtKB=B3S2Q7	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_27129\|UniProtKB=A9V4D9	Monosiga brevicollis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_22849\|UniProtKB=F4NVZ2	Batrachochytrium dendrobatidis	LDO
TRIV3\|Gene_ORFName=TVAG_065670\|UniProtKB=A2ELX1	Trichomonas vaginalis	O
PARTE\|EnsemblGenome=GSPATT00024345001\|UniProtKB=A0E8J9	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00015995001\|UniProtKB=A0DDN7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00019494001\|UniProtKB=A0DRX3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00010733001\|UniProtKB=A0CUR5	Paramecium tetraurelia	O
LEIMA\|EnsemblGenome=LMJF_29_2660\|UniProtKB=E9AEC8	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.3.3090\|UniProtKB=Q57ZK3	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_92673\|UniProtKB=A8BI67	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_013790\|UniProtKB=A2DDD4	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1408400\|UniProtKB=Q8IM12	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00016196001\|UniProtKB=A0DE87	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00012558001\|UniProtKB=A0D1W6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00010742001\|UniProtKB=A0CUS4	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00016216001\|UniProtKB=A0DEC3	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_32522\|UniProtKB=B8BYI1	Thalassiosira pseudonana	LDO
CHLRE\|EnsemblGenome=CHLRE_02g089608v5\|UniProtKB=A0A2K3E158	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00078p00189390\|UniProtKB=W1PA87	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_178G00010\|UniProtKB=A0A0K9PRE6	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma03_g21420\|UniProtKB=A0A804IEP8	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_000155mg\|UniProtKB=K3XE38	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3003G205100\|UniProtKB=A0A1B6Q4E8	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb161030\|UniProtKB=A0A804NHJ1	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0592900\|UniProtKB=A0A0P0V4R0	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g42410v3\|UniProtKB=A0A2K2DDF0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0268950\|UniProtKB=A0A8I6X658	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3D02G215000\|UniProtKB=A0A3B6GRF6	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3B02G242700\|UniProtKB=A0A3B6FMQ1	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G212600\|UniProtKB=A0A3B6EHR9	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_002949\|UniProtKB=A0A1U7ZAV4	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110787765\|UniProtKB=A0A9R0IEY2	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0415401\|UniProtKB=A0A251U073	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400198010\|UniProtKB=A0A9R1XN59	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a017765mg\|UniProtKB=A0A022Q2W7	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_10875\|UniProtKB=A0A2G3A3E8	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc03g120200.2\|UniProtKB=A0A3Q7GK99	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107794086\|UniProtKB=A0A1S4A631	Nicotiana tabacum	O
TOBAC\|Gene=LOC107778074\|UniProtKB=A0A1S3YNQ8	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_09s0002g04670\|UniProtKB=F6HYG0	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_F03013\|UniProtKB=A0A059BTJ8	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C06P54320.1\|UniProtKB=A0A078J498	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra035203\|UniProtKB=M4F2A5	Brassica campestris	O
BRACM\|EnsemblGenome=Bra003540\|UniProtKB=M4CH57	Brassica campestris	LDO
ARATH\|TAIR=locus=2016209\|UniProtKB=F4HQE2	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107937350\|UniProtKB=A0A1U8MFT9	Gossypium hirsutum	O
GOSHI\|Gene=LOC107924100\|UniProtKB=A0A1U8L924	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_028696\|UniProtKB=A0A061GBH2	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g001656mg\|UniProtKB=A0A067EJX3	Citrus sinensis	LDO
POPTR\|Gene_ORFName=POPTR_001G180200\|UniProtKB=A0A3N7EFU5	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_11G047500\|UniProtKB=A0A2C9UYK0	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0980890\|UniProtKB=B9SQD1	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_13G359400\|UniProtKB=K7M3U8	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g102150\|UniProtKB=G7II45	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr07_30250\|UniProtKB=A0A2I4DXZ7	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G446720\|UniProtKB=A0A0A0K6J7	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_3G071000\|UniProtKB=A0A251PWK2	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_77246\|UniProtKB=D8QTS9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_94786\|UniProtKB=D8RJV6	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c18_12550\|UniProtKB=A0A2K1J0U8	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0076s0066\|UniProtKB=A0A2R6WLU8	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000430260\|UniProtKB=A0A1Y1HMY1	Klebsormidium nitens	LDO
KORCO\|EnsemblGenome=Kcr_1439\|UniProtKB=B1L6V6	Korarchaeum cryptofilum	O
KORCO\|EnsemblGenome=Kcr_1088\|UniProtKB=B1L5V5	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO0313\|UniProtKB=Q980I2	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE3526\|UniProtKB=Q8ZSY2	Pyrobaculum aerophilum	O
PYRAE\|EnsemblGenome=PAE2991\|UniProtKB=Q8ZU14	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_2096\|UniProtKB=Q8TP28	Methanosarcina acetivorans	O
METAC\|EnsemblGenome=MA_0335\|UniProtKB=Q8TTU0	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_0942\|UniProtKB=Q58352	Methanocaldococcus jannaschii	LDO
HALSA\|EnsemblGenome=VNG_1383G\|UniProtKB=Q9HQ08	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_2476C\|UniProtKB=Q9HMM1	Halobacterium salinarum	O
HALSA\|EnsemblGenome=VNG_2441G\|UniProtKB=Q9HMP9	Halobacterium salinarum	LDO
THEKO\|EnsemblGenome=TK0784\|UniProtKB=Q5JH96	Thermococcus kodakaraensis	LDO
CHLAA\|EnsemblGenome=Caur_1621\|UniProtKB=A9WBN2	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO5802\|UniProtKB=O69978	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv1329c\|UniProtKB=P9WMR5	Mycobacterium tuberculosis	LDO
LISMO\|Gene=dinG\|UniProtKB=Q8Y604	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_22150\|UniProtKB=P50831	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_1565\|UniProtKB=Q81FL6	Bacillus cereus	O
BACSU\|EnsemblGenome=BSU_22400\|UniProtKB=P54394	Bacillus subtilis	LDO
GLOVI\|Gene=Q7NKM8_GLOVI\|UniProtKB=Q7NKM8	Gloeobacter violaceus	O
SYNY3\|Gene=P72618_SYNY3\|UniProtKB=P72618	Synechocystis	O
GLOVI\|Gene=Q7NN01_GLOVI\|UniProtKB=Q7NN01	Gloeobacter violaceus	LDO
LEPIN\|EnsemblGenome=LA_1875\|UniProtKB=Q8F513	Leptospira interrogans	LDO
RHOBA\|EnsemblGenome=RB8062\|UniProtKB=Q7UG83	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_358\|UniProtKB=O66684	Aquifex aeolicus	LDO
FUSNN\|EnsemblGenome=FN0743\|UniProtKB=Q8RFF8	Fusobacterium nucleatum	LDO
NEIMB\|EnsemblGenome=NMB0287\|UniProtKB=Q9K181	Neisseria meningitidis serogroup b	O
SHEON\|Gene_OrderedLocusName=SO_1819\|UniProtKB=Q8EFZ5	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_1855\|UniProtKB=Q9KQZ2	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC3950\|UniProtKB=Q8P3W9	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA1045\|UniProtKB=Q9I4S9	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM0821\|UniProtKB=Q8ZQN7	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO1206\|UniProtKB=A0A2S9PKW4	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA35465\|UniProtKB=P27296	Escherichia coli	O
GEOSL\|EnsemblGenome=GSU0363\|UniProtKB=Q74G84	Geobacter sulfurreducens	LDO
HAEIN\|EnsemblGenome=HI_0387\|UniProtKB=P44680	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_2081\|UniProtKB=Q8EFA4	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_1990\|UniProtKB=Q9KQK8	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC2930\|UniProtKB=Q8P6N7	Xanthomonas campestris	LDO
SALTY\|EnsemblGenome=STM1821\|UniProtKB=Q7CQD9	Salmonella typhimurium	LDO
YERPE\|Gene_OrderedLocusName=YPO2071\|UniProtKB=A0A3N4B3X5	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAA15617\|UniProtKB=P76257	Escherichia coli	LDO