PANTHER Gene Information

Gene Symbol(s):

HLH3B

Organism:

Drosophila melanogaster

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Gene Name:

Helix loop helix protein 3B

Gene ID:

FBgn0011276

Protein ID:

Q9W4X2

Persistent Id:

PTN000355535

Alternate Ids:

31249(GeneID)	FBgn0011276(FlyBase)
7290343(GI)	FBpp0070482(Ensembl_PRO)
BT022174(EMBL)	FBtr0070506(Ensembl_TRS)
Q9W4X2(Synonym)	NP_525055(refSeq)
AAF45802(EMBL-CDS)	Q9W4X2_DROME(UniProtKB-ID)
FBgn0011276(Ensembl)
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PANTHER Classification

PANTHER Family:	T-CELL ACUTE LYMPHOCYTIC LEUKEMIA/STEM CELL LEUKEMIA-RELATED (PTHR13864)
PANTHER Subfamily:	T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1 HOMOLOG-RELATED (PTHR13864:SF15)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	basic helix-loop-helix transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	RNA polymerase II cis-regulatory region sequence-specific DNA binding, protein dimerization activity, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	regulation of transcription by RNA polymerase II
GO CC Complete:	-

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Transcriptional regulation by RUNX1, Generic Transcription Pathway, RUNX1 regulates transcription of genes involved in differentiation of HSCs, RNA Polymerase II Transcription, Gene expression (Transcription)

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6734\|UniProtKB=P12980	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000049311.1\|UniProtKB=A0A2I3SC45	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000023512.2\|UniProtKB=G3S9D2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000001166.4\|UniProtKB=A0A1D5Q8V9	Macaca mulatta	O
MOUSE\|MGI=MGI=96891\|UniProtKB=P27792	Mus musculus	O
RAT\|RGD=1359244\|UniProtKB=Q66HH3	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000019329.4\|UniProtKB=E1BAR3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000024549.4\|UniProtKB=I3LGW2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000028699.2\|UniProtKB=A0A9L0SIP0	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845017510.1\|UniProtKB=A0A8I3NSN9	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00845030516.1\|UniProtKB=A0A8I3S7N2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000011593.2\|UniProtKB=F6UZP5	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000006846.3\|UniProtKB=F6QWY3	Ornithorhynchus anatinus	O
HUMAN\|HGNC=11556\|UniProtKB=P17542	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000051380.1\|UniProtKB=A0A2J8NIQ0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000043148.1\|UniProtKB=A0A2I2YGS1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000061850.1\|UniProtKB=A0A5F7ZU27	Macaca mulatta	LDO
MOUSE\|MGI=MGI=98480\|UniProtKB=P22091	Mus musculus	LDO
RAT\|RGD=1306748\|UniProtKB=D3Z921	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000005029.6\|UniProtKB=E1BAU0	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000058056.1\|UniProtKB=A0A286ZXS3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000018746.4\|UniProtKB=F6Z9C4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000045414.2\|UniProtKB=A0A5F5XJU7	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845016668.1\|UniProtKB=A0A8I3NR93	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000001502.5\|UniProtKB=F7F4H1	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000032005.2\|UniProtKB=K7E992	Ornithorhynchus anatinus	LDO
HUMAN\|HGNC=11557\|UniProtKB=Q16559	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000021225.3\|UniProtKB=H2QXM9	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000006780.3\|UniProtKB=G3QV69	Gorilla gorilla gorilla	O
MOUSE\|MGI=MGI=99540\|UniProtKB=Q62282	Mus musculus	O
RAT\|RGD=1596467\|UniProtKB=D3ZV67	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000045852.2\|UniProtKB=G3MZY5	Bos taurus	O
HORSE\|Ensembl=ENSECAG00000046843.1\|UniProtKB=A0A9L0TM06	Equus caballus	O
CANLF\|Ensembl=ENSCAFG00845011153.1\|UniProtKB=A0A8I3NCZ4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000022957.2\|UniProtKB=F6RH69	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000004194.2\|UniProtKB=F6TW32	Ornithorhynchus anatinus	O
CHICK\|Gene=TAL1\|UniProtKB=P24899	Gallus gallus	LDO
CHICK\|Ensembl=ENSGALG00010022991.1\|UniProtKB=A0A8V0ZTP8	Gallus gallus	LDO
CHICK\|Ensembl=ENSGALG00010012114.1\|UniProtKB=A0A3Q2TXR2	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000044312.1\|UniProtKB=A0A803T2J6	Anolis carolinensis	LDO
ANOCA\|Ensembl=ENSACAG00000004545.2\|UniProtKB=H9G964	Anolis carolinensis	O
XENLA\|Gene=tal1.L\|UniProtKB=A0A1L8GMB6	Xenopus laevis	O
XENLA\|Gene=tal1\|UniProtKB=O73823	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-479827\|UniProtKB=B5DEA1	Xenopus tropicalis	O
XENLA\|Gene=LOC108703405\|UniProtKB=A0A8J1MST8	Xenopus laevis	LDO
XENLA\|Gene=LOC108705239\|UniProtKB=A0A8J1MP43	Xenopus laevis	LDO
XENLA\|Gene=tal2.S\|UniProtKB=A0A1L8HNZ8	Xenopus laevis	O
DANRE\|ZFIN=ZDB-GENE-980526-501\|UniProtKB=O93507	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009966.1\|UniProtKB=W5MUX8	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000030528.1\|UniProtKB=A0A3B3IFB1	Oryzias latipes	LDO
ORYLA\|Ensembl=ENSORLG00000003776.2\|UniProtKB=H2LFG6	Oryzias latipes	LDO
ORYLA\|Ensembl=ENSORLG00000000466.2\|UniProtKB=H2L487	Oryzias latipes	O
DANRE\|Gene=lyl1\|UniProtKB=A0A8M3AT04	Danio rerio	LDO
DANRE\|ZFIN=ZDB-GENE-040115-1\|UniProtKB=F1QUD8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007669.1\|UniProtKB=W5MLP6	lepisosteus oculatus	LDO
LEPOC\|Ensembl=ENSLOCG00000017967.1\|UniProtKB=W5NN61	lepisosteus oculatus	O
BRAFL\|Gene=LOC118418503\|UniProtKB=A0A9J7MVF7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115925133\|UniProtKB=A0A7M7P0K1	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC587670\|UniProtKB=A0A7M7GH70	Strongylocentrotus purpuratus	LDO
ANOGA\|EnsemblGenome=AGAP004299\|UniProtKB=Q5TT24	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC033641\|UniProtKB=A0A139WFR5	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW010324\|UniProtKB=B7Q1X8	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g200658\|UniProtKB=A7RQN4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g200659\|UniProtKB=A7RQN5	Nematostella vectensis	LDO