PANTHER Gene Information   
Gene Symbol(s): Anapc7
Organism: Mus musculus
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Gene Name: Anaphase-promoting complex subunit 7
Gene ID: MGI:1929711
Protein ID: Q9WVM3
Persistent Id: PTN000285207
Alternate Ids:
ENSMUSG00000029466(Ensembl) 13879320(GI)
NP_062779(refSeq) BAE35152(EMBL-CDS)
APC7_MOUSE(UniProtKB-ID) Q3UBM7(AltAccession)
AF076607(EMBL) MGI:1929711(MGI)
Anapc7(Symbol) ENSMUST00000031422(Ensembl_TRS)
ENSMUSP00000031422(Ensembl_PRO) Apc7(Synonym)
56317(GeneID)
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PANTHER Classification
PANTHER Family: CELL DIVISION CYCLE 16,23,27 (PTHR12558)
PANTHER Subfamily: ANAPHASE-PROMOTING COMPLEX SUBUNIT 7 (PTHR12558:SF36)  
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process: positive regulation of mitotic cell cycle
regulation of mitotic sister chromatid separation
regulation of mitotic metaphase/anaphase transition
positive regulation of mitotic nuclear division
cell division
protein ubiquitination
PANTHER GO-slim Cellular Component: anaphase-promoting complex
PANTHER protein class: ubiquitin-protein ligase
Pathway Categories: No pathway information available
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: protein phosphatase binding, enzyme-substrate adaptor activity
GO BP Complete: cell division, protein K11-linked ubiquitination, protein K48-linked ubiquitination, anaphase-promoting complex-dependent catabolic process, positive regulation of mitotic metaphase/anaphase transition, brain development, protein branched polyubiquitination, protein ubiquitination
GO CC Complete: heterochromatin, nucleus, microtubule cytoskeleton, cytoplasm, anaphase-promoting complex, spindle
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Immune System, Cellular responses to stimuli, Inactivation of APC/C via direct inhibition of the APC/C complex, Separation of Sister Chromatids, Antigen processing: Ubiquitination & Proteasome degradation, Class I MHC mediated antigen processing & presentation, DNA Replication, Autodegradation of Cdh1 by Cdh1:APC/C, Cdc20:Phospho-APC/C mediated degradation of Cyclin A, Cell Cycle, Mitotic, Mitotic Anaphase, APC/C-mediated degradation of cell cycle proteins, Cellular Senescence, Senescence-Associated Secretory Phenotype (SASP), Switching of origins to a post-replicative state, Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase, APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint, Regulation of APC/C activators between G1/S and early anaphase, APC/C:Cdc20 mediated degradation of mitotic proteins, APC/C:Cdc20 mediated degradation of Cyclin B, M Phase, CDK-mediated phosphorylation and removal of Cdc6, Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components, Synthesis of DNA, Assembly of the pre-replicative complex, Mitotic Spindle Checkpoint, Regulation of mitotic cell cycle, S Phase, DNA Replication Pre-Initiation, APC/C:Cdc20 mediated degradation of Securin, Mitotic Metaphase and Anaphase, Cell Cycle Checkpoints, APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, Phosphorylation of the APC/C, Adaptive Immune System, Cell Cycle, Cellular responses to stress, Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, APC-Cdc20 mediated degradation of Nek2A

Orthologs