PANTHER Gene Information

Gene Symbol(s):

TM_0356

Organism:

Thermotoga maritima

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Tree

Gene Name:

threonine ammonia-lyase

Gene ID:

TM_0356

Protein ID:

Q9WYJ1

Persistent Id:

PTN002459405

Alternate Ids:

Q9WYJ1(Synonym)	TM_0356(Ensembl)
AE000512(EMBL)	AAD35443(EMBL-CDS)
NP_228167(refSeq)	4980859(GI)
Q9WYJ1_THEMA(UniProtKB-ID)	4.3.1.17 {ECO:0000269\|PubMed:33938999}(EC)
G4FHR8(AltAccession)
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PANTHER Classification

PANTHER Family:	THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED (PTHR48078)
PANTHER Subfamily:	L-THREONINE DEHYDRATASE CATABOLIC TDCB (PTHR48078:SF6)
PANTHER GO-slim Molecular Function:	lyase activity
PANTHER GO-slim Biological Process:	aspartate family amino acid metabolic process amino acid catabolic process branched-chain amino acid biosynthetic process alpha-amino acid biosynthetic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	dehydratase

Pathway Categories:

Isoleucine biosynthesis

Threonine dehydratase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	L-serine ammonia-lyase activity, pyridoxal phosphate binding, lyase activity, threonine deaminase activity
GO BP Complete:	isoleucine biosynthetic process, threonine catabolic process, L-serine catabolic process
GO CC Complete:	-

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=10691\|UniProtKB=P20132	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000005491.3\|UniProtKB=H2Q6Y1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000007318.3\|UniProtKB=G3QWK1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000004208.4\|UniProtKB=F6Z3Z0	Macaca mulatta	O
MOUSE\|MGI=MGI=98270\|UniProtKB=Q8VBT2	Mus musculus	O
RAT\|RGD=67376\|UniProtKB=P09367	Rattus norvegicus	O
BOVIN\|Gene=SDS\|UniProtKB=Q0VCW4	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000031814.3\|UniProtKB=F1N0R8	Bos taurus	O
PIG\|Ensembl=ENSSSCG00005034755.1\|UniProtKB=K9IVJ5	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000024950.4\|UniProtKB=A0A9L0R5E7	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000032375.3\|UniProtKB=A0A2I2US35	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845024052.1\|UniProtKB=A0A8I3PVD9	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000003535.4\|UniProtKB=F7GBQ6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000044882.1\|UniProtKB=A0A6I8PFD4	Ornithorhynchus anatinus	O
ANOCA\|Ensembl=ENSACAG00000042061.1\|UniProtKB=A0A803T9H3	Anolis carolinensis	O
XENLA\|Gene=sds.S\|UniProtKB=A1L2R8	Xenopus laevis	O
XENLA\|Gene=sds.L\|UniProtKB=A1L2T1	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-921978\|UniProtKB=F7BVD4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000023397.1\|UniProtKB=A0A3B3HKT1	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000029865.1\|UniProtKB=A0A3B3HDD3	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000026663.1\|UniProtKB=A0A3B3IPC2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000024632.1\|UniProtKB=A0A3B3IKV0	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000007734.1\|UniProtKB=W5MLY1	lepisosteus oculatus	O
HUMAN\|HGNC=30404\|UniProtKB=Q96GA7	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000005492.5\|UniProtKB=H2Q6Y2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010575.3\|UniProtKB=G3R4U7	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000020665.4\|UniProtKB=F7BEL5	Macaca mulatta	O
MOUSE\|MGI=MGI=2182607\|UniProtKB=Q8R238	Mus musculus	O
RAT\|RGD=1309192\|UniProtKB=D3ZHV7	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000008945.5\|UniProtKB=A5PKH5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00005034510.1\|UniProtKB=A0A4X1TIZ3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000022258.4\|UniProtKB=A0A3Q2LE78	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005084.6\|UniProtKB=M3W3F5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845024122.1\|UniProtKB=A0A8I3PH52	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000003565.4\|UniProtKB=F7G139	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000037171.1\|UniProtKB=A0A6I8P497	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010000447.1\|UniProtKB=A0A8V0X067	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000005037.4\|UniProtKB=H9G9U1	Anolis carolinensis	O
XENLA\|Gene=sdsl.S\|UniProtKB=Q6PAE9	Xenopus laevis	O
XENLA\|Gene=LOC121399475\|UniProtKB=A0A8J1M3A8	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-922203\|UniProtKB=A0A6I8Q911	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000026856.1\|UniProtKB=A0A3B3HZL1	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-131121-410\|UniProtKB=A0A8M9PEB6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000007758.1\|UniProtKB=W5MM16	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000022604.1\|UniProtKB=H2XNN8	Ciona intestinalis	O
BRAFL\|Gene=LOC118425400\|UniProtKB=A0A9J7LWP2	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC594261\|UniProtKB=A0A7M7P9A3	Strongylocentrotus purpuratus	O
HELRO\|EnsemblGenome=HelroG105471\|UniProtKB=T1EDV2	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g241178\|UniProtKB=A7RWI2	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG28057\|UniProtKB=B3S1X5	Trichoplax adhaerens	O
YEAST\|SGD=S000000569\|UniProtKB=P25379	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFR747W\|UniProtKB=Q751S7	Eremothecium gossypii	O
CANAL\|CGD=CAL0000177673\|UniProtKB=A0A1D8PGA8	Candida albicans	O
CANAL\|CGD=CAL0000177340\|UniProtKB=A0A1D8PKG0	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B16214g\|UniProtKB=Q6CEE8	Yarrowia lipolytica	O
YARLI\|EnsemblGenome=YALI0_E10307g\|UniProtKB=Q6C6D8	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_03866\|UniProtKB=Q5B6G4	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G07810\|UniProtKB=Q4WP28	Neosartorya fumigata	O
EMENI\|EnsemblGenome=ANIA_04217\|UniProtKB=C8V4B5	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_1G06150\|UniProtKB=Q4WJF6	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03761\|UniProtKB=Q1K7B4	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_06079\|UniProtKB=A7EL82	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_03797\|UniProtKB=Q0UWR7	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_09456\|UniProtKB=Q0UFK8	Phaeosphaeria nodorum	O
CRYNJ\|EnsemblGenome=CNK00180\|UniProtKB=Q5K9Z3	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNE02390\|UniProtKB=Q5KGT7	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_01692\|UniProtKB=A0A0D1E4A6	Ustilago maydis	O
DICDI\|dictyBase=DDB_G0272787\|UniProtKB=Q86B06	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_98285\|UniProtKB=F0ZP75	Dictyostelium purpureum	O
THAPS\|EnsemblGenome=THAPSDRAFT_262207\|UniProtKB=B8BZN7	Thalassiosira pseudonana	O
BRAFL\|Gene=LOC118410170\|UniProtKB=A0A9J7KP48	Branchiostoma floridae	LDO
TRIAD\|EnsemblGenome=TriadG60349\|UniProtKB=B3S7Z2	Trichoplax adhaerens	LDO
PARTE\|EnsemblGenome=GSPATT00027414001\|UniProtKB=A0EIE4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00034883001\|UniProtKB=A0C3N7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00018614001\|UniProtKB=A0DMZ2	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020953001\|UniProtKB=A0DW95	Paramecium tetraurelia	LDO
CHLRE\|EnsemblGenome=CHLRE_14g632759v5\|UniProtKB=A0A2K3CYU0	Chlamydomonas reinhardtii	LDO
ORYLA\|Ensembl=ENSORLG00000024885.1\|UniProtKB=A0A3B3HUW7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-110914-210\|UniProtKB=H0WEF6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000016071.1\|UniProtKB=W5NGP3	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000006752.3\|UniProtKB=F6Y0K7	Ciona intestinalis	O
BRAFL\|Gene=LOC118405036\|UniProtKB=A0A9J7HLW8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118416035\|UniProtKB=A0A9J7L6E2	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC584103\|UniProtKB=A0A7M7TGY5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC764115\|UniProtKB=A0A7M7HJQ5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115925516\|UniProtKB=A0A7M7P2Z6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC593088\|UniProtKB=A0A7M7HMG8	Strongylocentrotus purpuratus	O
ORNAN\|Ensembl=ENSOANG00000040840.1\|UniProtKB=A0A6I8PH84	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010008893.1\|UniProtKB=A0A8V0XV31	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000024834.3\|UniProtKB=H9GR95	Anolis carolinensis	O
XENLA\|Gene=LOC108703378\|UniProtKB=A0A8J0TUB7	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5822196\|UniProtKB=A0A6I8QNB6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000000468.2\|UniProtKB=A0A3B3I8G5	Oryzias latipes	O
DANRE\|Gene=LOC100331665\|UniProtKB=A0A8M9PYW7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012908.1\|UniProtKB=W5N5I6	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000009373.3\|UniProtKB=F6WXJ5	Ciona intestinalis	O
BRAFL\|Gene=LOC118431804\|UniProtKB=A0A9J7NAI4	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC115918011\|UniProtKB=A0A7M7PHB9	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00021787\|UniProtKB=Q95XY8	Caenorhabditis elegans	O
PRIPA\|EnsemblGenome=WBGene00116091\|UniProtKB=A0A2A6C7P2	Pristionchus pacificus	O
CAEEL\|WormBase=WBGene00010456\|UniProtKB=Q21080	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00024026\|UniProtKB=A8WNC1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00112373\|UniProtKB=A0A8R1UG80	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0037684\|UniProtKB=Q9VHF0	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP003571\|UniProtKB=F5HLA9	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC008704\|UniProtKB=D6WSN2	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_302120\|UniProtKB=E9GBI8	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW007433\|UniProtKB=B7PUC9	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG73017\|UniProtKB=T1G187	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG185307\|UniProtKB=T1FMN2	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g93245\|UniProtKB=A7RTQ8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g93233\|UniProtKB=A7RTQ7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g84834\|UniProtKB=A7RKN0	Nematostella vectensis	O
MONBE\|EnsemblGenome=MONBRDRAFT_16023\|UniProtKB=A9UVQ8	Monosiga brevicollis	O
ENTH1\|EnsemblGenome=CL6EHI_049910\|UniProtKB=C4LUI9	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_126080\|UniProtKB=C4LVZ3	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=EHI_056920\|UniProtKB=B1N610	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_092390\|UniProtKB=B1N2N4	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0277245\|UniProtKB=Q86AP7	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_51500\|UniProtKB=F1A425	Dictyostelium purpureum	O
GIAIC\|EnsemblGenome=GL50803_12108\|UniProtKB=A8BFR5	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_375350\|UniProtKB=A2FH13	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_362020\|UniProtKB=A2FRC0	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_090490\|UniProtKB=A2FA06	Trichomonas vaginalis	O
THAPS\|EnsemblGenome=THAPSDRAFT_14147\|UniProtKB=B8C333	Thalassiosira pseudonana	O
PHYRM\|Gene=H3G667_PHYRM\|UniProtKB=H3G667	Phytophthora ramorum	O
MEDTR\|EnsemblGenome=MTR_0681s0020\|UniProtKB=A0A072TEJ7	Medicago truncatula	O
KLENI\|Gene_ORFName=KFL_002630130\|UniProtKB=A0A1Y1I971	Klebsormidium nitens	O
NITMS\|EnsemblGenome=Nmar_1549\|UniProtKB=A9A4Z1	Nitrosopumilus maritimus	LDO
NITMS\|EnsemblGenome=Nmar_0848\|UniProtKB=A9A5N3	Nitrosopumilus maritimus	O
KORCO\|EnsemblGenome=Kcr_0521\|UniProtKB=B1L495	Korarchaeum cryptofilum	LDO
SACS2\|EnsemblGenome=SSO0248\|UniProtKB=Q980P1	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE2316\|UniProtKB=Q8ZVF0	Pyrobaculum aerophilum	LDO
HALSA\|EnsemblGenome=VNG_2100G\|UniProtKB=Q9HNH6	Halobacterium salinarum	LDO
CHLAA\|EnsemblGenome=Caur_1249\|UniProtKB=A9WK26	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_3892\|UniProtKB=A9WDF0	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO7292\|UniProtKB=Q9K4M2	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4962\|UniProtKB=Q9EWG3	Streptomyces coelicolor	LDO
CLOBH\|Gene_OrderedLocusName=CBO3502\|UniProtKB=A5I7M9	Clostridium botulinum	LDO
DICTD\|EnsemblGenome=Dtur_1494\|UniProtKB=B8E131	Dictyoglomus turgidum	LDO
FUSNN\|EnsemblGenome=FN1411\|UniProtKB=Q8RDT9	Fusobacterium nucleatum	LDO
BRADU\|Gene=Q89G45_BRADU\|UniProtKB=Q89G45	Bradyrhizobium diazoefficiens	O
PSEAE\|EnsemblGenome=PA0851\|UniProtKB=Q9I590	Pseudomonas aeruginosa	O
GEOSL\|EnsemblGenome=GSU0486\|UniProtKB=Q74FW6	Geobacter sulfurreducens	LDO
BRADU\|Gene=Q89UK3_BRADU\|UniProtKB=Q89UK3	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=Q89L17_BRADU\|UniProtKB=Q89L17	Bradyrhizobium diazoefficiens	LDO
XANCP\|EnsemblGenome=XCC3326\|UniProtKB=Q8P5L2	Xanthomonas campestris	LDO
SALTY\|EnsemblGenome=STM3244\|UniProtKB=P11954	Salmonella typhimurium	LDO
ECOLI\|EnsemblGenome=BAE77166\|UniProtKB=P0AGF6	Escherichia coli	LDO