PANTHER Gene Information

Gene Symbol(s):

egas-3

Organism:

Caenorhabditis elegans

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Gene Name:

EGF-like domain-containing protein

Gene ID:

WBGene00013480

Protein ID:

Q9XTS9

Persistent Id:

PTN001234910

Alternate Ids:

WBGene00013480(WormBase)	NM_075237(refSeq)
Y69H2(WormBase_TRS)	CE41527(WormBase_PRO)
BX284605(EMBL)	Q9XTS9(Synonym)
156557600(GI)	CAB11570(EMBL-CDS)
Q9XTS9_CAEEL(UniProtKB-ID)	WBGene00013480(Ensembl)
190557(GeneID)
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PANTHER Classification

PANTHER Family:	AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED (PTHR11690)
PANTHER Subfamily:	EGF-LIKE DOMAIN-CONTAINING PROTEIN (PTHR11690:SF177)
PANTHER GO-slim Molecular Function:	sodium channel activity ligand-gated monoatomic cation channel activity
PANTHER GO-slim Biological Process:	sodium ion transmembrane transport
PANTHER GO-slim Cellular Component:	plasma membrane
PANTHER protein class:	ion channel

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	calcium ion binding, sodium channel activity, ligand-gated sodium channel activity
GO BP Complete:	sodium ion transport, monoatomic ion transmembrane transport, sodium ion transmembrane transport
GO CC Complete:	membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Sensory perception of salty taste, Stimuli-sensing channels, Transport of small molecules, Sensory perception of taste, Ion channel transport, Sensory Perception

Orthologs

ID	Organism	Type
XENLA\|Gene=LOC108698154\|UniProtKB=A0A8J0T9R2	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000037695\|UniProtKB=A0A6I8R4H5	Xenopus tropicalis	O
XENLA\|Gene=scnn1gl.L\|UniProtKB=A0A8J0UQG4	Xenopus laevis	O
XENTR\|Gene=scnn1gl\|UniProtKB=A0A8J0T2F9	Xenopus tropicalis	O
LEPOC\|Ensembl=ENSLOCG00000010927.1\|UniProtKB=W5MYE1	lepisosteus oculatus	O
HUMAN\|HGNC=10602\|UniProtKB=P51170	Homo sapiens	O
PANTR\|Gene=SCNN1G\|UniProtKB=H2QAR5	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000007883.3\|UniProtKB=A0A2J8JK94	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000007380.3\|UniProtKB=G3QWQ8	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000005699.4\|UniProtKB=F6U4Y2	Macaca mulatta	O
MOUSE\|MGI=MGI=104695\|UniProtKB=Q9WU39	Mus musculus	O
RAT\|RGD=3641\|UniProtKB=P37091	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000010163\|UniProtKB=F1MJW3	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000007836.5\|UniProtKB=F1RPF1	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000021259.4\|UniProtKB=A0A9L0RBL4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005172.5\|UniProtKB=M3W3L6	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845001972.1\|UniProtKB=A0A8I3MKE6	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000006857.4\|UniProtKB=F6Q7G2	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000014302.3\|UniProtKB=F7C6F7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010017296.1\|UniProtKB=F1NW62	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000014662.3\|UniProtKB=H9GLJ5	Anolis carolinensis	O
XENLA\|Gene=scnn1g-b\|UniProtKB=O13263	Xenopus laevis	O
XENLA\|Gene=scnn1g-a\|UniProtKB=P51171	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-980897\|UniProtKB=F6W3N3	Xenopus tropicalis	O
HUMAN\|HGNC=10601\|UniProtKB=P51172	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000000017.7\|UniProtKB=H2RAT4	Pan troglodytes	O
PANTR\|Gene=SCNN1D\|UniProtKB=O46547	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000005342.3\|UniProtKB=A0A2I2YP72	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000032292.3\|UniProtKB=F7G694	Macaca mulatta	O
BOVIN\|Ensembl=ENSBTAG00000017674.5\|UniProtKB=F1MY57	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000027991.4\|UniProtKB=A0A287BBK2	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000010898.4\|UniProtKB=A0A9L0RP06	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000007609.6\|UniProtKB=M3W812	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845023300.1\|UniProtKB=A0A8I3PET1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000023686.2\|UniProtKB=F6SJE4	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000001638.3\|UniProtKB=F7DAT7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010018450.1\|UniProtKB=A0A8V0Z5Y4	Gallus gallus	O
XENLA\|Gene=scnn1d.L\|UniProtKB=Q7SZG4	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-991876\|UniProtKB=F6VMZ3	Xenopus tropicalis	O
XENLA\|Gene=LOC108696566\|UniProtKB=A0A1L8FM49	Xenopus laevis	O
XENTR\|Gene=LOC100497753\|UniProtKB=A0A8J0QUS8	Xenopus tropicalis	O
HUMAN\|HGNC=10600\|UniProtKB=P51168	Homo sapiens	O
PANTR\|Gene=SCNN1B\|UniProtKB=H2QAR6	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000007884.4\|UniProtKB=A0A2I3SU17	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000001543.3\|UniProtKB=G3RMU9	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000000524.4\|UniProtKB=F7A3T9	Macaca mulatta	O
MOUSE\|MGI=MGI=104696\|UniProtKB=Q9WU38	Mus musculus	O
RAT\|RGD=3640\|UniProtKB=P37090	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012290\|UniProtKB=A5D7U4	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000028923.3\|UniProtKB=I3LGX7	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000014993.4\|UniProtKB=A0A3Q2H7F7	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000005173.6\|UniProtKB=M3W3L7	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845001896.1\|UniProtKB=A0A8I3N0E7	Canis lupus familiaris	O
CANLF\|Ensembl=ENSCAFG00000017687\|UniProtKB=Q95165	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000006819.3\|UniProtKB=F6PGF0	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000014301.3\|UniProtKB=A0A6I8N545	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010017490.1\|UniProtKB=A0A8V0Z1H1	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000000508.4\|UniProtKB=H9G438	Anolis carolinensis	O
XENLA\|Gene=scnn1b-b\|UniProtKB=O13262	Xenopus laevis	O
XENLA\|Gene=scnn1b-a\|UniProtKB=P51169	Xenopus laevis	O
XENLA\|Gene=scnn1b.L\|UniProtKB=Q6DE38	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-949109\|UniProtKB=Q0V998	Xenopus tropicalis	O
HUMAN\|HGNC=10599\|UniProtKB=P37088	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000004571\|UniProtKB=H2Q5A1	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000010834.3\|UniProtKB=A0A2I2YQN1	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000020212.4\|UniProtKB=F6V9V4	Macaca mulatta	O
MOUSE\|MGI=MGI=101782\|UniProtKB=Q61180	Mus musculus	O
RAT\|RGD=3639\|UniProtKB=P37089	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000002631\|UniProtKB=P55270	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000000707.5\|UniProtKB=A0A480QJ99	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000001443.3\|UniProtKB=A0A9L0TJP6	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000006869.6\|UniProtKB=A0A2I2URC6	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845029331.1\|UniProtKB=A0A8I3Q679	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000001688.3\|UniProtKB=A0A6I8PB29	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010021866.1\|UniProtKB=A0A8V0ZTC6	Gallus gallus	O
CHICK\|Gene=SCNN1A\|UniProtKB=Q92075	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000006704\|UniProtKB=H9GBX2	Anolis carolinensis	O
XENLA\|Gene=scnn1a.S\|UniProtKB=A0A1L8FE22	Xenopus laevis	O
XENLA\|Gene=scnn1a\|UniProtKB=P51167	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-996083\|UniProtKB=F7AE39	Xenopus tropicalis	O
BRAFL\|Gene=LOC118428532\|UniProtKB=A0A9J7N9P2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409427\|UniProtKB=A0A9J7HVH7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409702\|UniProtKB=A0A9J7KMS0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118429346\|UniProtKB=A0A9J7NAG0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100892792\|UniProtKB=A0A7M7N8Z6	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891497\|UniProtKB=A0A7M7SUT4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC580984\|UniProtKB=A0A7M7HLK0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105441174\|UniProtKB=A0A7M7HF55	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100894064\|UniProtKB=A0A7M7SUH3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891818\|UniProtKB=A0A7M7NFP2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891272\|UniProtKB=A0A7M7SV08	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC594671\|UniProtKB=A0A7M7PLZ2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100893645\|UniProtKB=A0A7M7LW68	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100889460\|UniProtKB=A0A7M7HQL8	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100889526\|UniProtKB=A0A7M7HK48	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC590960\|UniProtKB=A0A7M7N8K7	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105436466\|UniProtKB=A0A7M7N8V4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890654\|UniProtKB=A0A7M7N7N9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC105446529\|UniProtKB=A0A7M7SUJ3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100891438\|UniProtKB=A0A7M7N919	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC763355\|UniProtKB=A0A7M7GA14	Strongylocentrotus purpuratus	O
PRIPA\|EnsemblGenome=WBGene00278527\|UniProtKB=A0A2A6C4X9	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00117929\|UniProtKB=A0A2A6CKC6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00282848\|UniProtKB=A0A2A6BSU9	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096858\|UniProtKB=A0A2A6C5A6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00101875\|UniProtKB=A0A2A6CSQ8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00272170\|UniProtKB=A0A2A6BSL6	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00096852\|UniProtKB=A0A2A6C5E4	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00095605\|UniProtKB=A0A2A6C3N7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0032602\|UniProtKB=Q9VJI4	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP010146\|UniProtKB=Q7Q0V0	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC005481\|UniProtKB=D6WY25	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW017829\|UniProtKB=B7PEV5	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW028495\|UniProtKB=A0A905FYF3	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW002325\|UniProtKB=A0A1S4KQ07	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW023720\|UniProtKB=B7QI61	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g213150\|UniProtKB=A7SJB5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g218891\|UniProtKB=A7SX71	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g136400\|UniProtKB=A7SX80	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211338\|UniProtKB=A7SF69	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215544\|UniProtKB=A7SPS2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215206\|UniProtKB=A7SP23	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211570\|UniProtKB=A7SFR0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g205746\|UniProtKB=A7S2F2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211334\|UniProtKB=A7SF65	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g211571\|UniProtKB=A7SFR1	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG54579\|UniProtKB=B3RSF6	Trichoplax adhaerens	O