PANTHER Gene Information

Gene Symbol(s):

Y63D3A.4

Organism:

Caenorhabditis elegans

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Gene Name:

5'-tyrosyl-DNA phosphodiesterase

Gene ID:

WBGene00013405

Protein ID:

Q9XWG3

Persistent Id:

PTN001813464

Alternate Ids:

410562902(GI)	Y63D3A.4(Ensembl_PRO)
CAA21707(EMBL-CDS)	WBGene00013405(Ensembl)
Y63D3A.4(Ensembl_TRS)	AL032652(EMBL)
Y63D3A(WormBase_TRS)	TYDP2(Synonym)
WBGene00013405(WormBase)	CE20335(WormBase_PRO)
3.1.4.-(EC)	173276(GeneID)
TYDP2_CAEEL(UniProtKB-ID)	NP_493461(refSeq)
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PANTHER Classification

PANTHER Family:	TRAF AND TNF RECEPTOR-ASSOCIATED PROTEIN (PTHR15822)
PANTHER Subfamily:	TYROSYL-DNA PHOSPHODIESTERASE 2 (PTHR15822:SF4)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	identical protein binding, 5'-tyrosyl-DNA phosphodiesterase activity, catalytic activity, metal ion binding, nuclease activity, single-stranded DNA binding
GO BP Complete:	DNA repair, double-strand break repair
GO CC Complete:	nucleus, PML body, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=17768\|UniProtKB=O95551	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017778.6\|UniProtKB=K7DBQ3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014237.3\|UniProtKB=G3REA7	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000009803.4\|UniProtKB=F6PMX6	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1860486\|UniProtKB=Q9JJX7	Mus musculus	LDO
RAT\|RGD=1560342\|UniProtKB=Q3T1H5	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000000365\|UniProtKB=A7YWI9	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000001092.5\|UniProtKB=F1RUE1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014264.3\|UniProtKB=F7CD61	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000025612.4\|UniProtKB=M3WQI6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845020279.1\|UniProtKB=A0A8I3P722	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000011653.4\|UniProtKB=A0A5F8GEF8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000045197.1\|UniProtKB=A0A6I8MXF7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010008035.1\|UniProtKB=A0A8V0XVJ6	Gallus gallus	LDO
CHICK\|Gene=TDP2\|UniProtKB=F1NW29	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000002332.4\|UniProtKB=G1KAK0	Anolis carolinensis	LDO
XENLA\|Gene=tdp2.S\|UniProtKB=A0A8J0VPQ5	Xenopus laevis	LDO
XENLA\|Gene=tdp2\|UniProtKB=A5D8M0	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000001661.2\|UniProtKB=A0A3B3IHL8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000012815.2\|UniProtKB=H2MBW9	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-110218-1\|UniProtKB=E7FEU2	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050816-1\|UniProtKB=Q5XJA0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005817.1\|UniProtKB=W5MF67	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118407382\|UniProtKB=A0A9J7KKM0	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC764829\|UniProtKB=A0A7M7N2Q4	Strongylocentrotus purpuratus	LDO
CAEBR\|Gene_ORFName=CBG18823\|UniProtKB=A8XU68	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00278628\|UniProtKB=A0A2A6BVD8	Pristionchus pacificus	LDO
TRICA\|EnsemblGenome=TC007396\|UniProtKB=D1ZZU9	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_305861\|UniProtKB=E9GTF5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW013768\|UniProtKB=B7QJH1	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW020529\|UniProtKB=B7Q1G6	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG116381\|UniProtKB=T1EGE4	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g198586\|UniProtKB=A7RKW0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g203425\|UniProtKB=A7RX17	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g246978\|UniProtKB=A7SRP8	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG53975\|UniProtKB=B3RMK0	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_8188\|UniProtKB=A9UZB2	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_37105\|UniProtKB=A9UZL7	Monosiga brevicollis	LDO
CANAL\|CGD=CAL0000175369\|UniProtKB=A0A1D8PT33	Candida albicans	LDO
EMENI\|EnsemblGenome=ANIA_02637\|UniProtKB=Q5B9Z3	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G13650\|UniProtKB=Q4X0F5	Neosartorya fumigata	LDO
PHANO\|EnsemblGenome=SNOG_05657\|UniProtKB=Q0URF7	Phaeosphaeria nodorum	LDO
USTMA\|EnsemblGenome=UMAG_03381\|UniProtKB=A0A0D1DYV5	Ustilago maydis	LDO
DICDI\|dictyBase=DDB_G0269692\|UniProtKB=Q55DD6	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_79391\|UniProtKB=F0ZMF8	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_16_0740\|UniProtKB=Q4QEU5	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_26_0860\|UniProtKB=Q6T443	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.70.3850\|UniProtKB=Q38BP2	Trypanosoma brucei	O
TRYB2\|Gene_ORFName=Tb927.7.1070\|UniProtKB=Q57WU3	Trypanosoma brucei	LDO
PARTE\|EnsemblGenome=GSPATT00023588001\|UniProtKB=A0E544	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00025316001\|UniProtKB=A0EBB5	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_2194\|UniProtKB=B8BTN1	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_23010\|UniProtKB=B8C5A1	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3HB44_PHYRM\|UniProtKB=H3HB44	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_06g305250v5\|UniProtKB=A0A2K3DRA1	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_12g521600v5\|UniProtKB=A0A2K3D449	Chlamydomonas reinhardtii	O
CHLRE\|EnsemblGenome=CHLRE_06g305050v5\|UniProtKB=A0A2K3DR93	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00037p00211070\|UniProtKB=U5D589	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_53G00180\|UniProtKB=A0A0K9NX42	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma04_g39900\|UniProtKB=A0A804IZ34	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_032299mg\|UniProtKB=K4A0B0	Setaria italica	O
BRADI\|EnsemblGenome=BRADI_1g26500v3\|UniProtKB=I1GU26	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0318330\|UniProtKB=A0A8I6X8P8	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS3B02G521700\|UniProtKB=A0A3B6G056	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G473500\|UniProtKB=A0A3B6H5A9	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_033155mg\|UniProtKB=K4A2Q3	Setaria italica	O
BRADI\|EnsemblGenome=BRADI_1g26491v3\|UniProtKB=A0A0Q3GYX1	Brachypodium distachyon	O
WHEAT\|EnsemblGenome=TraesCS5D02G344800\|UniProtKB=A0A3B6MXG2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G339400\|UniProtKB=A0A3B6LRI3	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_038635mg\|UniProtKB=K4AIC5	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3001G255600\|UniProtKB=C5WMB3	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb048580\|UniProtKB=B4F826	Zea mays	O
SETIT\|EnsemblGenome=SETIT_039663mg\|UniProtKB=K4AL83	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G190400\|UniProtKB=C5WVA1	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb043220\|UniProtKB=A0A1D6KQJ0	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os12g0414900\|UniProtKB=Q2QSX3	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g11470v3\|UniProtKB=A0A2K2CM45	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_5g07131v3\|UniProtKB=A0A0Q3GN21	Brachypodium distachyon	O
BRADI\|EnsemblGenome=BRADI_2g11520v3\|UniProtKB=I1HEU2	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0567060\|UniProtKB=A0A8I6YR91	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1A02G372500\|UniProtKB=A0A3B5Y6E9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6A02G140500\|UniProtKB=A0A3B6NMR3	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS1D02G379100\|UniProtKB=A0A3B6A022	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS6D02G128400\|UniProtKB=A0A3B6QCA7	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_024856\|UniProtKB=A0A1U8BBC3	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110792541\|UniProtKB=A0A9R0IQB2	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr05g0193251\|UniProtKB=A0A251UKC2	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0680041\|UniProtKB=A0A251S6L5	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C700348720\|UniProtKB=A0A9R1X234	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a007120mg\|UniProtKB=A0A022QGC9	Erythranthe guttata	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400019871\|UniProtKB=M1BRD5	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc02g032870.3\|UniProtKB=A0A3Q7EXP7	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107826971\|UniProtKB=A0A1S4D835	Nicotiana tabacum	O
TOBAC\|Gene=LOC107814620\|UniProtKB=A0A1S4C3B9	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi10g00084\|UniProtKB=F6H7K7	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_D01342\|UniProtKB=A0A059CFI9	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C08P47960.1\|UniProtKB=A0A078HAX5	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00057382001\|UniProtKB=A0A078HAU3	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra031783\|UniProtKB=M4ESK4	Brassica campestris	LDO
ARATH\|TAIR=locus=2027417\|UniProtKB=Q9SA95	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107960178\|UniProtKB=A0A1U8PL91	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_030246\|UniProtKB=A0A061GNQ8	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g012811mg\|UniProtKB=A0A067GEZ3	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_004G010900v3\|UniProtKB=A0A2K2ANA2	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_004G010400v3\|UniProtKB=A0A2K2AN93	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_16G005800\|UniProtKB=A0A2C9U7N6	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0903920\|UniProtKB=B9RXJ5	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_07G261700\|UniProtKB=I1KNE7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_17G012400\|UniProtKB=I1MR47	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g132300\|UniProtKB=G7JJ90	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr03_11360\|UniProtKB=A0A2I4H142	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_1G062360\|UniProtKB=A0A0A0LRJ9	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G019000\|UniProtKB=A0A251PED1	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_112184\|UniProtKB=D8SAI1	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_78670\|UniProtKB=D8QVG2	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c20_16850\|UniProtKB=A0A2K1IVH9	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0074s0008\|UniProtKB=A0A2R6WMC5	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0028s0073\|UniProtKB=A0A2R6X9H6	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000370370\|UniProtKB=A0A1Y1HP01	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_001750050\|UniProtKB=A0A1Y1I7I6	Klebsormidium nitens	LDO