PANTHER Gene Information   
Gene Symbol(s): exc-5
Organism: Caenorhabditis elegans
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Gene Name: DH domain-containing protein
Gene ID: WBGene00001366
Protein ID: X5LV34
Persistent Id: PTN002290687
Alternate Ids:
X5LV34_CAEEL(UniProtKB-ID) NP_001294029(refSeq)
WBGene00001366(Ensembl) 604719446(GI)
BX284604(EMBL) CDO41070(EMBL-CDS)
C33D9.1c(WormBase_TRS) X5LV34(Synonym)
WBGene00001366(WormBase) CE49651(WormBase_PRO)
177692(GeneID)
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PANTHER Classification
PANTHER Family: FACIOGENITAL DYSPLASIA PROTEIN (PTHR12673)
PANTHER Subfamily: DH DOMAIN-CONTAINING PROTEIN (PTHR12673:SF241)  
PANTHER GO-slim Molecular Function: guanyl-nucleotide exchange factor activity
PANTHER GO-slim Biological Process: filopodium assembly
cytoskeleton organization
PANTHER GO-slim Cellular Component: cytoplasm
PANTHER protein class: guanyl-nucleotide exchange factor
Pathway Categories: No pathway information available
GO MF Complete: metal ion binding, guanyl-nucleotide exchange factor activity
GO BP Complete: cytoskeleton organization, regulation of tube size, cell morphogenesis, positive regulation of actin filament binding, epithelial cell development, filopodium assembly
GO CC Complete: cytoskeleton, apical part of cell, cytoplasm, cell body, actin cytoskeleton, apical cortex, cell projection
Reactome Pathways: p75 NTR receptor-mediated signalling, NRAGE signals death through JNK, Signaling by GPCR, Signal Transduction, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, Cell death signalling via NRAGE, NRIF and NADE, Signaling by Rho GTPases, GPCR downstream signalling, RHO GTPase cycle, Death Receptor Signaling, CDC42 GTPase cycle, G alpha (12/13) signalling events