Enhancer Detail Information

Enhancer: EH37E0210375
Chromosome Location: chr11:18408926-18409139
Source: ENCODE

Gene: HUMAN|HGNC=28335|UniProtKB=Q6ZMR3 (LDHAL6A)
Tissue Assay pValue SNP zScore CDFScore
Testis (Testis) single-tissue eQTL 1.77109e-11 11_18408963_G_C_b37 - -
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-MEL-5 (melanoma; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
ACHN (epithelial; Kidney; renal cell adenocarcinoma) Topologically Associated Domain - - - -
DLD1 (epithelial; Colon; colorectal adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
brain_pericyte (pericyte; Brain) Topologically Associated Domain - - - -
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
HepG2 (epithelial; Liver; carcinoma) - - - -.51 .42
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.27 .61
K562 (lymphoblast; Bone marrow; leukemia) - - - -.27 .40
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - -.71 .20


Gene: HUMAN|HGNC=6535|UniProtKB=P00338 (LDHA)
Tissue Assay pValue SNP zScore CDFScore
Adipose Subcutaneous (Adipose tissue) single-tissue eQTL 9.35957e-07 11_18408963_G_C_b37 - -
Lung (Lung) single-tissue eQTL 8.2751e-10 11_18408963_G_C_b37 - -
Muscle Skeletal (Skeletal muscle) single-tissue eQTL 1.96625e-06 11_18408963_G_C_b37 - -
Nerve Tibial (Nerve) single-tissue eQTL 1.30098e-06 11_18408963_G_C_b37 - -
Thyroid (Thyroid gland) single-tissue eQTL 9.91196e-13 11_18408963_G_C_b37 - -
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-MEL-5 (melanoma; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
ACHN (epithelial; Kidney; renal cell adenocarcinoma) Topologically Associated Domain - - - -
DLD1 (epithelial; Colon; colorectal adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
brain_pericyte (pericyte; Brain) Topologically Associated Domain - - - -
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
HepG2 (epithelial; Liver; carcinoma) - - - 1.17 .95
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.26 .97
K562 (lymphoblast; Bone marrow; leukemia) - - - -.26 .48
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - .71 .90


Gene: HUMAN|HGNC=4655|UniProtKB=P32780 (GTF2H1)
Tissue Assay pValue SNP zScore CDFScore
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-MEL-5 (melanoma; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
ACHN (epithelial; Kidney; renal cell adenocarcinoma) Topologically Associated Domain - - - -
DLD1 (epithelial; Colon; colorectal adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
brain_pericyte (pericyte; Brain) Topologically Associated Domain - - - -
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
GM12878 (B-lymphocyte; Blood; normal) interaction TAD 3.8e-05 - - -
HMEC (epithelial; Breast; normal) interaction TAD 1.1e-05 - - -
HepG2 (epithelial; Liver; carcinoma) - - - 1.29 .96
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.09 .75
K562 (lymphoblast; Bone marrow; leukemia) - - - -.09 .83
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - .13 .62


Gene: HUMAN|HGNC=17022|UniProtKB=Q9UPZ3 (HPS5)
Tissue Assay pValue SNP zScore CDFScore
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-MEL-5 (melanoma; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
ACHN (epithelial; Kidney; renal cell adenocarcinoma) Topologically Associated Domain - - - -
DLD1 (epithelial; Colon; colorectal adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
brain_pericyte (pericyte; Brain) Topologically Associated Domain - - - -
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
GM12878 (B-lymphocyte; Blood; normal) interaction TAD 3.8e-05 - - -
HMEC (epithelial; Breast; normal) interaction TAD 1.1e-05 - - -
HepG2 (epithelial; Liver; carcinoma) - - - .76 .91
HCT116 (epithelial; colon; colorectal carcinoma) - - - .04 .79
K562 (lymphoblast; Bone marrow; leukemia) - - - .04 .89
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - .05 .55


Gene: HUMAN|HGNC=6544|UniProtKB=P07864 (LDHC)
Tissue Assay pValue SNP zScore CDFScore
Adipose Subcutaneous (Adipose tissue) single-tissue eQTL 2.10654e-12 11_18408963_G_C_b37 - -
Brain Cerebellum (Brain) single-tissue eQTL 2.92419e-06 11_18408963_G_C_b37 - -
Brain Cortex (Brain) single-tissue eQTL 2.69717e-07 11_18408963_G_C_b37 - -
Brain Frontal Cortex BA9 (Brain) single-tissue eQTL 2.62815e-06 11_18408963_G_C_b37 - -
Brain Hippocampus (Brain) single-tissue eQTL 4.0495e-07 11_18408963_G_C_b37 - -
Brain Nucleus accumbens basal ganglia (Brain) single-tissue eQTL 1.40445e-06 11_18408963_G_C_b37 - -
Brain Substantia nigra (Brain) single-tissue eQTL 3.93153e-07 11_18408963_G_C_b37 - -
Adipose Visceral Omentum (Adipose tissue) single-tissue eQTL 1.10861e-13 11_18408963_G_C_b37 - -
Breast Mammary Tissue (Breast) single-tissue eQTL 1.06681e-08 11_18408963_G_C_b37 - -
Cells Transformed fibroblasts (fibroblast) single-tissue eQTL 1.86891e-10 11_18408963_G_C_b37 - -
Colon Sigmoid (Colon) single-tissue eQTL 1.44817e-06 11_18408963_G_C_b37 - -
Colon Transverse (Colon) single-tissue eQTL 7.95802e-10 11_18408963_G_C_b37 - -
Esophagus Gastroesophageal Junction (Esophagus) single-tissue eQTL 2.06528e-10 11_18408963_G_C_b37 - -
Esophagus Mucosa (Esophagus) single-tissue eQTL 7.67031e-12 11_18408963_G_C_b37 - -
Esophagus Muscularis (Esophagus) single-tissue eQTL 2.23397e-13 11_18408963_G_C_b37 - -
Heart Atrial Appendage (Heart) single-tissue eQTL 6.81618e-08 11_18408963_G_C_b37 - -
Heart Left Ventricle (Heart) single-tissue eQTL 3.25575e-09 11_18408963_G_C_b37 - -
Adrenal Gland (Adrenal gland) single-tissue eQTL 1.03953e-07 11_18408963_G_C_b37 - -
Liver (Liver) single-tissue eQTL 3.76597e-09 11_18408963_G_C_b37 - -
Lung (Lung) single-tissue eQTL 4.80664e-15 11_18408963_G_C_b37 - -
Muscle Skeletal (Skeletal muscle) single-tissue eQTL 5.13908e-20 11_18408963_G_C_b37 - -
Nerve Tibial (Nerve) single-tissue eQTL 1.05382e-14 11_18408963_G_C_b37 - -
Pancreas (Pancreas) single-tissue eQTL 4.30091e-07 11_18408963_G_C_b37 - -
Pituitary (Pituitary gland) single-tissue eQTL 1.29829e-07 11_18408963_G_C_b37 - -
Prostate (Prostate) single-tissue eQTL 8.81303e-09 11_18408963_G_C_b37 - -
Skin Not Sun Exposed Suprapubic (Skin) single-tissue eQTL 1.17584e-12 11_18408963_G_C_b37 - -
Artery Aorta (Aorta) single-tissue eQTL 2.99963e-07 11_18408963_G_C_b37 - -
Skin Sun Exposed Lower leg (Skin) single-tissue eQTL 3.56682e-14 11_18408963_G_C_b37 - -
Stomach (Stomach) single-tissue eQTL 9.29615e-06 11_18408963_G_C_b37 - -
Thyroid (Thyroid gland) single-tissue eQTL 5.58413e-14 11_18408963_G_C_b37 - -
Whole Blood (Blood) single-tissue eQTL 2.38608e-09 11_18408963_G_C_b37 - -
Artery Tibial (Artery) single-tissue eQTL 9.53436e-12 11_18408963_G_C_b37 - -
Brain Amygdala (Brain) single-tissue eQTL 3.298e-06 11_18408963_G_C_b37 - -
Brain Anterior cingulate cortex BA24 (Brain) single-tissue eQTL 5.72026e-06 11_18408963_G_C_b37 - -
Brain Caudate basal ganglia (Brain) single-tissue eQTL 3.45615e-07 11_18408963_G_C_b37 - -
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-MEL-5 (melanoma; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
ACHN (epithelial; Kidney; renal cell adenocarcinoma) Topologically Associated Domain - - - -
DLD1 (epithelial; Colon; colorectal adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
brain_pericyte (pericyte; Brain) Topologically Associated Domain - - - -
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
HepG2 (epithelial; Liver; carcinoma) - - - -.52 .38
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.36 .41
K562 (lymphoblast; Bone marrow; leukemia) - - - -.36 .02
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - -.83 .01