Enhancer Detail Information

Enhancer:	EH37E0210404
Chromosome Location:	chr11:18516831-18517261
Source:	ENCODE

Gene:

HUMAN|HGNC=28335|UniProtKB=Q6ZMR3 (LDHAL6A)

Tissue	Assay	pValue	SNP	zScore	CDFScore
Testis (Testis)	single-tissue eQTL	1.80507e-05	11_18516917_A_G_b37	-	-
Testis (Testis)	single-tissue eQTL	7.30358e-06	11_18517021_A_G_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
DLD1 (epithelial; Colon; colorectal adenocarcinoma)	Topologically Associated Domain	-	-	-	-
astrocyte_of_the_cerebellum (astrocyte; Cerebellum)	Topologically Associated Domain	-	-	-	-
brain_microvascular_endothelial_cell (microvascular endothelium; Brain)	Topologically Associated Domain	-	-	-	-
brain_pericyte (pericyte; Brain)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	-.56	.24
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	-.28	.43
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	-.28	.36
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	-.72	.19

Gene:

HUMAN|HGNC=6535|UniProtKB=P00338 (LDHA)

Tissue	Assay	pValue	SNP	zScore	CDFScore
Lung (Lung)	single-tissue eQTL	1.74202e-08	11_18516917_A_G_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
DLD1 (epithelial; Colon; colorectal adenocarcinoma)	Topologically Associated Domain	-	-	-	-
astrocyte_of_the_cerebellum (astrocyte; Cerebellum)	Topologically Associated Domain	-	-	-	-
brain_microvascular_endothelial_cell (microvascular endothelium; Brain)	Topologically Associated Domain	-	-	-	-
brain_pericyte (pericyte; Brain)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	.53	.86
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	-.17	.78
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	-.17	.73
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	.07	.57

Gene:

HUMAN|HGNC=6544|UniProtKB=P07864 (LDHC)

Tissue	Assay	pValue	SNP	zScore	CDFScore
Adipose Subcutaneous (Adipose tissue)	single-tissue eQTL	1.66238e-05	11_18516917_A_G_b37	-	-
Adipose Subcutaneous (Adipose tissue)	single-tissue eQTL	8.51774e-10	11_18517021_A_G_b37	-	-
Cells EBV-transformed lymphocytes (lymphocyte; Blood)	single-tissue eQTL	7.46376e-06	11_18517021_A_G_b37	-	-
Cells Transformed fibroblasts (fibroblast)	single-tissue eQTL	3.69234e-07	11_18517021_A_G_b37	-	-
Colon Sigmoid (Colon)	single-tissue eQTL	7.61589e-06	11_18517021_A_G_b37	-	-
Colon Transverse (Colon)	single-tissue eQTL	2.58166e-07	11_18517021_A_G_b37	-	-
Esophagus Mucosa (Esophagus)	single-tissue eQTL	1.84721e-05	11_18517021_A_G_b37	-	-
Esophagus Muscularis (Esophagus)	single-tissue eQTL	3.23271e-05	11_18517021_A_G_b37	-	-
Heart Atrial Appendage (Heart)	single-tissue eQTL	1.08434e-06	11_18517021_A_G_b37	-	-
Heart Left Ventricle (Heart)	single-tissue eQTL	8.52477e-06	11_18517021_A_G_b37	-	-
Lung (Lung)	single-tissue eQTL	1.42644e-08	11_18517021_A_G_b37	-	-
Muscle Skeletal (Skeletal muscle)	single-tissue eQTL	1.8995e-07	11_18516917_A_G_b37	-	-
Muscle Skeletal (Skeletal muscle)	single-tissue eQTL	4.03325e-09	11_18517021_A_G_b37	-	-
Nerve Tibial (Nerve)	single-tissue eQTL	3.65348e-07	11_18516917_A_G_b37	-	-
Nerve Tibial (Nerve)	single-tissue eQTL	7.82318e-10	11_18517021_A_G_b37	-	-
Pancreas (Pancreas)	single-tissue eQTL	1.4974e-05	11_18517021_A_G_b37	-	-
Skin Sun Exposed Lower leg (Skin)	single-tissue eQTL	2.30001e-10	11_18517021_A_G_b37	-	-
Skin Sun Exposed Lower leg (Skin)	single-tissue eQTL	9.47682e-09	11_18516917_A_G_b37	-	-
Thyroid (Thyroid gland)	single-tissue eQTL	1.96649e-06	11_18517021_A_G_b37	-	-
Thyroid (Thyroid gland)	single-tissue eQTL	4.19115e-05	11_18516917_A_G_b37	-	-
Artery Tibial (Artery)	single-tissue eQTL	7.46598e-09	11_18517021_A_G_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
DLD1 (epithelial; Colon; colorectal adenocarcinoma)	Topologically Associated Domain	-	-	-	-
astrocyte_of_the_cerebellum (astrocyte; Cerebellum)	Topologically Associated Domain	-	-	-	-
brain_microvascular_endothelial_cell (microvascular endothelium; Brain)	Topologically Associated Domain	-	-	-	-
brain_pericyte (pericyte; Brain)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	-.56	.24
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	-.28	.43
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	-.28	.34
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	-.78	.10