Enhancer Detail Information

Enhancer: EH37E0265873
Chromosome Location: chr12:48122953-48123429
Source: ENCODE

Gene: HUMAN|HGNC=14067|UniProtKB=Q8WUI4 (HDAC7)
Tissue Assay pValue SNP zScore CDFScore
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
ACHN (epithelial; Kidney; renal cell adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
HUVEC (endothelial; Umbilical; normal) interaction TAD 8.7e-07 - - -
K562 (lymphoblast; Bone marrow; leukemia) interaction TAD 7.4e-06 - -.24 .51
KBM7 (blood cell; Bone marrow; leukemia) interaction TAD 3.4e-06 - - -
HepG2 (epithelial; Liver; carcinoma) - - - -.51 .40
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.24 .49
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - -.37 .40


Gene: HUMAN|HGNC=16629|UniProtKB=O95398 (RAPGEF3)
Tissue Assay pValue SNP zScore CDFScore
Cells Transformed fibroblasts (fibroblast) single-tissue eQTL 8.38317e-06 12_48123429_T_G_b37 - -
Esophagus Mucosa (Esophagus) single-tissue eQTL 3.28313e-08 12_48123178_A_G_b37 - -
Lung (Lung) single-tissue eQTL 7.07434e-06 12_48123178_A_G_b37 - -
Skin Sun Exposed Lower leg (Skin) single-tissue eQTL 5.5863e-06 12_48123260_G_A_b37 - -
Stomach (Stomach) single-tissue eQTL 2.12364e-05 12_48123260_G_A_b37 - -
Thyroid (Thyroid gland) single-tissue eQTL 2.68799e-07 12_48123178_A_G_b37 - -
Whole Blood (Blood) single-tissue eQTL 1.16688e-08 12_48123178_A_G_b37 - -
Whole Blood (Blood) single-tissue eQTL 2.29068e-08 12_48123429_T_G_b37 - -
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
ACHN (epithelial; Kidney; renal cell adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
GM12878 (B-lymphocyte; Blood; normal) interaction TAD 0 - - -
HMEC (epithelial; Breast; normal) interaction TAD 9.6e-06 - - -
HUVEC (endothelial; Umbilical; normal) interaction TAD 0 - - -
IMR90 (fibroblast; Lung; normal) interaction TAD 0 - - -
K562 (lymphoblast; Bone marrow; leukemia) interaction TAD 0 - -.36 .02
KBM7 (blood cell; Bone marrow; leukemia) interaction TAD 2.5e-09 - - -
HepG2 (epithelial; Liver; carcinoma) - - - -.52 .38
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.36 .65
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - -.32 .41


Gene: HUMAN|HGNC=14369|UniProtKB=P21128 (ENDOU)
Tissue Assay pValue SNP zScore CDFScore
Esophagus Mucosa (Esophagus) single-tissue eQTL 1.34288e-07 12_48123429_T_G_b37 - -
Thyroid (Thyroid gland) single-tissue eQTL 9.13607e-06 12_48123178_A_G_b37 - -
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-MEL-5 (melanoma; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
HepG2 (epithelial; Liver; carcinoma) - - - -.36 .54
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.37 .98
K562 (lymphoblast; Bone marrow; leukemia) - - - -.37 .01
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - -.05 .46


Gene: HUMAN|HGNC=26035|UniProtKB=Q6P1K1 (SLC48A1)
Tissue Assay pValue SNP zScore CDFScore
Nerve Tibial (Nerve) single-tissue eQTL 2.35865e-05 12_48123429_T_G_b37 - -
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
ACHN (epithelial; Kidney; renal cell adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
GM12878 (B-lymphocyte; Blood; normal) interaction TAD 0 - - -
HMEC (epithelial; Breast; normal) interaction TAD 9.6e-06 - - -
HUVEC (endothelial; Umbilical; normal) interaction TAD 0 - - -
IMR90 (fibroblast; Lung; normal) interaction TAD 0 - - -
K562 (lymphoblast; Bone marrow; leukemia) interaction TAD 0 - -.26 .48
KBM7 (blood cell; Bone marrow; leukemia) interaction TAD 2.5e-09 - - -
HepG2 (epithelial; Liver; carcinoma) - - - -.53 .33
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.26 .49
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - -.36 .40


Gene: HUMAN|HGNC=26151|UniProtKB=Q9H6T3 (RPAP3)
Tissue Assay pValue SNP zScore CDFScore
Whole Blood (Blood) single-tissue eQTL 1.67672e-05 12_48123429_T_G_b37 - -
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-MEL-5 (melanoma; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
HepG2 (epithelial; Liver; carcinoma) - - - .40 .81
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.09 .76
K562 (lymphoblast; Bone marrow; leukemia) - - - -.09 .83
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - -.34 .41