Enhancer Detail Information

Enhancer:	EH37E0484724
Chromosome Location:	chr19:18228558-18228833
Source:	ENCODE

Gene:

HUMAN|HGNC=8782|UniProtKB=Q08493 (PDE4C)

Tissue	Assay	pValue	SNP	zScore	CDFScore
Testis (Testis)	single-tissue eQTL	2.85245e-09	19_18228619_C_T_b37	-	-
Artery Tibial (Artery)	single-tissue eQTL	9.30975e-06	19_18228680_C_T_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
DLD1 (epithelial; Colon; colorectal adenocarcinoma)	Topologically Associated Domain	-	-	-	-
astrocyte_of_the_cerebellum (astrocyte; Cerebellum)	Topologically Associated Domain	-	-	-	-
brain_microvascular_endothelial_cell (microvascular endothelium; Brain)	Topologically Associated Domain	-	-	-	-
brain_pericyte (pericyte; Brain)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	-.65	.00
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	.50	.95
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	.50	.94
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	-.88	.00

Gene:

HUMAN|HGNC=29350|UniProtKB=Q9H0B3 (IQCN)

Tissue	Assay	pValue	SNP	zScore	CDFScore
Esophagus Muscularis (Esophagus)	single-tissue eQTL	3.07404e-06	19_18228680_C_T_b37	-	-
Nerve Tibial (Nerve)	single-tissue eQTL	1.89817e-06	19_18228680_C_T_b37	-	-
Skin Sun Exposed Lower leg (Skin)	single-tissue eQTL	6.32028e-06	19_18228680_C_T_b37	-	-
Thyroid (Thyroid gland)	single-tissue eQTL	1.72771e-07	19_18228680_C_T_b37	-	-
Artery Tibial (Artery)	single-tissue eQTL	2.70584e-06	19_18228680_C_T_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
DLD1 (epithelial; Colon; colorectal adenocarcinoma)	Topologically Associated Domain	-	-	-	-
astrocyte_of_the_cerebellum (astrocyte; Cerebellum)	Topologically Associated Domain	-	-	-	-
brain_microvascular_endothelial_cell (microvascular endothelium; Brain)	Topologically Associated Domain	-	-	-	-
brain_pericyte (pericyte; Brain)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	.14	.66
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	.83	.54
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	.83	.94
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	-.84	.01

Gene:

HUMAN|HGNC=8980|UniProtKB=O00459 (PIK3R2)

Tissue	Assay	pValue	SNP	zScore	CDFScore
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
DLD1 (epithelial; Colon; colorectal adenocarcinoma)	Topologically Associated Domain	-	-	-	-
astrocyte_of_the_cerebellum (astrocyte; Cerebellum)	Topologically Associated Domain	-	-	-	-
brain_microvascular_endothelial_cell (microvascular endothelium; Brain)	Topologically Associated Domain	-	-	-	-
brain_pericyte (pericyte; Brain)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
IMR90 (fibroblast; Lung; normal)	interaction TAD	8.5e-06	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	.89	.93
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	4.43	.45
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	4.43	.98
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	-.04	.47