Enhancer Detail Information

Enhancer:	EH37E0484726
Chromosome Location:	chr19:18229788-18230204
Source:	ENCODE

Gene:

HUMAN|HGNC=8782|UniProtKB=Q08493 (PDE4C)

Tissue	Assay	pValue	SNP	zScore	CDFScore
Artery Tibial (Artery)	single-tissue eQTL	1.96944e-05	19_18229907_G_C_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
DLD1 (epithelial; Colon; colorectal adenocarcinoma)	Topologically Associated Domain	-	-	-	-
astrocyte_of_the_cerebellum (astrocyte; Cerebellum)	Topologically Associated Domain	-	-	-	-
brain_microvascular_endothelial_cell (microvascular endothelium; Brain)	Topologically Associated Domain	-	-	-	-
brain_pericyte (pericyte; Brain)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	-.38	.53
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	-.30	.84
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	-.30	.27
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	-.61	.30

Gene:

HUMAN|HGNC=29350|UniProtKB=Q9H0B3 (IQCN)

Tissue	Assay	pValue	SNP	zScore	CDFScore
Nerve Tibial (Nerve)	single-tissue eQTL	2.67859e-06	19_18229907_G_C_b37	-	-
Skin Sun Exposed Lower leg (Skin)	single-tissue eQTL	6.16819e-06	19_18229907_G_C_b37	-	-
Thyroid (Thyroid gland)	single-tissue eQTL	7.22373e-07	19_18229907_G_C_b37	-	-
Artery Tibial (Artery)	single-tissue eQTL	1.5894e-05	19_18229907_G_C_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
DLD1 (epithelial; Colon; colorectal adenocarcinoma)	Topologically Associated Domain	-	-	-	-
astrocyte_of_the_cerebellum (astrocyte; Cerebellum)	Topologically Associated Domain	-	-	-	-
brain_microvascular_endothelial_cell (microvascular endothelium; Brain)	Topologically Associated Domain	-	-	-	-
brain_pericyte (pericyte; Brain)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	.66	.89
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	-.22	.44
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	-.22	.62
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	-.55	.34

Gene:

HUMAN|HGNC=8980|UniProtKB=O00459 (PIK3R2)

Tissue	Assay	pValue	SNP	zScore	CDFScore
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
DLD1 (epithelial; Colon; colorectal adenocarcinoma)	Topologically Associated Domain	-	-	-	-
astrocyte_of_the_cerebellum (astrocyte; Cerebellum)	Topologically Associated Domain	-	-	-	-
brain_microvascular_endothelial_cell (microvascular endothelium; Brain)	Topologically Associated Domain	-	-	-	-
brain_pericyte (pericyte; Brain)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
IMR90 (fibroblast; Lung; normal)	interaction TAD	8.5e-06	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	1.49	.97
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	-.13	.44
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	-.13	.79
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	.45	.81