Enhancer Detail Information

Enhancer: EH37E0484735
Chromosome Location: chr19:18248491-18248841
Source: ENCODE

Gene: HUMAN|HGNC=5971|UniProtKB=P42701 (IL12RB1)
Tissue Assay pValue SNP zScore CDFScore
Lung (Lung) single-tissue eQTL 3.40374e-09 19_18248499_C_T_b37 - -
Nerve Tibial (Nerve) single-tissue eQTL 2.35109e-05 19_18248499_C_T_b37 - -
Spleen (Spleen) single-tissue eQTL 1.23299e-05 19_18248499_C_T_b37 - -
Whole Blood (Blood) single-tissue eQTL 2.68458e-07 19_18248499_C_T_b37 - -
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-MEL-5 (melanoma; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
ACHN (epithelial; Kidney; renal cell adenocarcinoma) Topologically Associated Domain - - - -
DLD1 (epithelial; Colon; colorectal adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
brain_pericyte (pericyte; Brain) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
HepG2 (epithelial; Liver; carcinoma) - - - -.25 .56
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.18 .25
K562 (lymphoblast; Bone marrow; leukemia) - - - -.18 .72
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - -.68 .23


Gene: HUMAN|HGNC=8782|UniProtKB=Q08493 (PDE4C)
Tissue Assay pValue SNP zScore CDFScore
Muscle Skeletal (Skeletal muscle) single-tissue eQTL 1.28323e-05 19_18248499_C_T_b37 - -
Testis (Testis) single-tissue eQTL 4.34342e-07 19_18248499_C_T_b37 - -
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-MEL-5 (melanoma; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
ACHN (epithelial; Kidney; renal cell adenocarcinoma) Topologically Associated Domain - - - -
DLD1 (epithelial; Colon; colorectal adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
brain_pericyte (pericyte; Brain) Topologically Associated Domain - - - -
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
HepG2 (epithelial; Liver; carcinoma) - - - -.29 .56
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.30 .80
K562 (lymphoblast; Bone marrow; leukemia) - - - -.30 .26
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - -.71 .19


Gene: HUMAN|HGNC=29350|UniProtKB=Q9H0B3 (IQCN)
Tissue Assay pValue SNP zScore CDFScore
Adipose Subcutaneous (Adipose tissue) single-tissue eQTL 2.66392e-05 19_18248499_C_T_b37 - -
Brain Cortex (Brain) single-tissue eQTL 8.9962e-07 19_18248499_C_T_b37 - -
Lung (Lung) single-tissue eQTL 4.36671e-07 19_18248499_C_T_b37 - -
Nerve Tibial (Nerve) single-tissue eQTL 1.42211e-08 19_18248499_C_T_b37 - -
Skin Not Sun Exposed Suprapubic (Skin) single-tissue eQTL 4.01164e-07 19_18248499_C_T_b37 - -
Thyroid (Thyroid gland) single-tissue eQTL 2.69258e-07 19_18248499_C_T_b37 - -
Whole Blood (Blood) single-tissue eQTL 4.84519e-06 19_18248499_C_T_b37 - -
Artery Tibial (Artery) single-tissue eQTL 9.68235e-06 19_18248499_C_T_b37 - -
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-MEL-5 (melanoma; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
DLD1 (epithelial; Colon; colorectal adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
brain_pericyte (pericyte; Brain) Topologically Associated Domain - - - -
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
HepG2 (epithelial; Liver; carcinoma) - - - 1.42 .96
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.21 .52
K562 (lymphoblast; Bone marrow; leukemia) - - - -.21 .65
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - -.68 .23


Gene: HUMAN|HGNC=8980|UniProtKB=O00459 (PIK3R2)
Tissue Assay pValue SNP zScore CDFScore
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-MEL-5 (melanoma; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
ACHN (epithelial; Kidney; renal cell adenocarcinoma) Topologically Associated Domain - - - -
DLD1 (epithelial; Colon; colorectal adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
brain_pericyte (pericyte; Brain) Topologically Associated Domain - - - -
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
IMR90 (fibroblast; Lung; normal) interaction TAD 8.5e-06 - - -
HepG2 (epithelial; Liver; carcinoma) - - - 2.65 .98
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.14 .79
K562 (lymphoblast; Bone marrow; leukemia) - - - -.14 .78
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - .04 .55


Gene: HUMAN|HGNC=28177|UniProtKB=Q567V2 (MPV17L2)
Tissue Assay pValue SNP zScore CDFScore
Cells Transformed fibroblasts (fibroblast) single-tissue eQTL 5.69104e-06 19_18248499_C_T_b37 - -
A549 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Caki2 (epithelial; Kidney; carcinoma) Topologically Associated Domain - - - -
G401 (epithelial; Kidney; rhabdoid tumor) Topologically Associated Domain - - - -
LNCap_clone_FGC (epithelial; Prostate; carcinoma) Topologically Associated Domain - - - -
NCI-H460 (epithelial; Lung; carcinoma) Topologically Associated Domain - - - -
Panc1 (epithelial; Pancreas; carcinoma) Topologically Associated Domain - - - -
RPMI-7951 (epithelial; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma) Topologically Associated Domain - - - -
SK-MEL-5 (melanoma; Skin; Malignant melanoma) Topologically Associated Domain - - - -
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma) Topologically Associated Domain - - - -
SK-N-MC (epithelial; Brain; neuroepithelioma) Topologically Associated Domain - - - -
T47D (epithelial; Mammary gland; carcinoma) Topologically Associated Domain - - - -
ACHN (epithelial; Kidney; renal cell adenocarcinoma) Topologically Associated Domain - - - -
DLD1 (epithelial; Colon; colorectal adenocarcinoma) Topologically Associated Domain - - - -
astrocyte_of_the_cerebellum (astrocyte; Cerebellum) Topologically Associated Domain - - - -
brain_microvascular_endothelial_cell (microvascular endothelium; Brain) Topologically Associated Domain - - - -
brain_pericyte (pericyte; Brain) Topologically Associated Domain - - - -
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium) Topologically Associated Domain - - - -
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver) Topologically Associated Domain - - - -
HepG2 (epithelial; Liver; carcinoma) - - - 1.51 .97
HCT116 (epithelial; colon; colorectal carcinoma) - - - -.17 .73
K562 (lymphoblast; Bone marrow; leukemia) - - - -.17 .74
MCF7 (epithelial; Mammary gland; adenocarcinoma) - - - .15 .65