PANTHER Enhancer Information

Associated enhancers for HUMAN|HGNC=18136|UniProtKB=P62341

Enhancer:	EH37E0690882
Source:	ENCODE

Tissue	Assay	pValue	SNP	zScore	CDFScore
Heart Atrial Appendage (Heart)	single-tissue eQTL	1.49776e-05	3_150306309_GA_G_b37	-	-
Heart Atrial Appendage (Heart)	single-tissue eQTL	1.49776e-05	3_150306562_T_A_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	.20	.71
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	-.11	.51
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	-.11	.82
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	.68	.89

Enhancer:	EH37E0690870
Source:	ENCODE

Tissue	Assay	pValue	SNP	zScore	CDFScore
Cells Transformed fibroblasts (fibroblast)	single-tissue eQTL	9.90477e-07	3_150259267_G_A_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	.22	.72
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	-.11	.44
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	-.11	.82
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	.70	.90

Enhancer:	EH37E0690903
Source:	ENCODE

Tissue	Assay	pValue	SNP	zScore	CDFScore
Cells Transformed fibroblasts (fibroblast)	single-tissue eQTL	1.13622e-06	3_150348951_G_C_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	.68	.89
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	-.27	.93
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	-.27	.39
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	1.26	.97

Enhancer:	EH37E0690904
Source:	ENCODE

Tissue	Assay	pValue	SNP	zScore	CDFScore
Heart Atrial Appendage (Heart)	single-tissue eQTL	3.20974e-07	3_150348974_G_A_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	.59	.87
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	-.26	.92
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	-.26	.48
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	1.30	.97

Enhancer:	EH37E0690868
Source:	ENCODE

Tissue	Assay	pValue	SNP	zScore	CDFScore
Brain Cerebellum (Brain)	single-tissue eQTL	7.72661e-06	3_150256012_G_A_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	.17	.69
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	-.13	.59
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	-.13	.80
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	1.73	.98

Enhancer:	EH37E0690889
Source:	ENCODE

Tissue	Assay	pValue	SNP	zScore	CDFScore
Cells Transformed fibroblasts (fibroblast)	single-tissue eQTL	3.12104e-07	3_150317570_G_T_b37	-	-
Heart Atrial Appendage (Heart)	single-tissue eQTL	9.15835e-06	3_150317636_T_C_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	.22	.72
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	6.23	.93
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	6.23	.99
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	1.19	.96

Enhancer:	EH37E0690883
Source:	ENCODE

Tissue	Assay	pValue	SNP	zScore	CDFScore
Heart Atrial Appendage (Heart)	single-tissue eQTL	1.49776e-05	3_150307873_G_T_b37	-	-
A549 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Caki2 (epithelial; Kidney; carcinoma)	Topologically Associated Domain	-	-	-	-
G401 (epithelial; Kidney; rhabdoid tumor)	Topologically Associated Domain	-	-	-	-
LNCap_clone_FGC (epithelial; Prostate; carcinoma)	Topologically Associated Domain	-	-	-	-
NCI-H460 (epithelial; Lung; carcinoma)	Topologically Associated Domain	-	-	-	-
Panc1 (epithelial; Pancreas; carcinoma)	Topologically Associated Domain	-	-	-	-
RPMI-7951 (epithelial; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SJCRH30 (fibroblast; Muscle; rhabdomyosarcoma)	Topologically Associated Domain	-	-	-	-
SK-MEL-5 (melanoma; Skin; Malignant melanoma)	Topologically Associated Domain	-	-	-	-
SK-N-DZ_not_treated_and_treated_with_dimethyl_sulfoxide (neuroblast; Brain; neuroblastoma)	Topologically Associated Domain	-	-	-	-
SK-N-MC (epithelial; Brain; neuroepithelioma)	Topologically Associated Domain	-	-	-	-
T47D (epithelial; Mammary gland; carcinoma)	Topologically Associated Domain	-	-	-	-
ACHN (epithelial; Kidney; renal cell adenocarcinoma)	Topologically Associated Domain	-	-	-	-
endometrial_microvascular_endothelial_cells (microvascular endothelium; Uterine endometrium)	Topologically Associated Domain	-	-	-	-
endothelial_cell_of_hepatic_sinusoid (endothelial; Liver)	Topologically Associated Domain	-	-	-	-
HepG2 (epithelial; Liver; carcinoma)	-	-	-	.27	.75
HCT116 (epithelial; colon; colorectal carcinoma)	-	-	-	2.77	.55
K562 (lymphoblast; Bone marrow; leukemia)	-	-	-	2.77	.97
MCF7 (epithelial; Mammary gland; adenocarcinoma)	-	-	-	.60	.87