PANTHER Gene Information

Gene Symbol(s):

HMA4

Organism:

Arabidopsis thaliana

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Gene Name:

Putative cadmium_zinc-transporting ATPase HMA4

Gene ID:

2059083

Protein ID:

O64474

Persistent Id:

PTN000644035

Alternate Ids:

Protein HEAVY METAL ATPASE 4(Synonym)	NM_001335622(refSeq)
AT2G19110(Ensembl)	ANM62253(EMBL-CDS)
HMA4(Symbol)	1063700744(GI)
AJ297264(EMBL)	AT2G19110(Ensembl_TRS)
ARA:AT2G19110-MON(BioCyc)	7.2.2.21(EC)
locus:2059083(TAIR)	HMA4_ARATH(UniProtKB-ID)
816428(GeneID)	AT2G19110(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	CADMIUM/ZINC-TRANSPORTING ATPASE HMA2-RELATED (PTHR48085)
PANTHER Subfamily:	CADMIUM_ZINC-TRANSPORTING ATPASE HMA4-RELATED (PTHR48085:SF5)
PANTHER GO-slim Molecular Function:	transmembrane transporter activity
PANTHER GO-slim Biological Process:	transmembrane transport
PANTHER GO-slim Cellular Component:	membrane
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ABC-type cadmium transporter activity, ATP hydrolysis activity, protein binding, P-type cadmium transporter activity, transmembrane transporter activity, cadmium ion transmembrane transporter activity, zinc ion transmembrane transporter activity, P-type zinc transporter activity
GO BP Complete:	response to zinc ion, transmembrane transport, zinc ion transport, cadmium ion transport, intracellular zinc ion homeostasis, response to cobalt ion, response to metal ion, response to cadmium ion, metal ion transport
GO CC Complete:	plasmodesma, membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g70040\|UniProtKB=A7RYT4	Nematostella vectensis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_261657\|UniProtKB=B8BX05	Thalassiosira pseudonana	LDO
AMBTC\|EnsemblGenome=AMTR_s00038p00036580\|UniProtKB=U5CWL0	Amborella trichopoda	O
AMBTC\|EnsemblGenome=AMTR_s00025p00176690\|UniProtKB=W1PX39	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_11G00410\|UniProtKB=A0A0K9Q3I1	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_462G00040\|UniProtKB=A0A0K9P050	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma05_g25070\|UniProtKB=A0A804J8B0	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma04_g36690\|UniProtKB=A0A804IXW5	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma08_g25480\|UniProtKB=A0A804KAM6	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_033111mg\|UniProtKB=K4A2L2	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3002G083100\|UniProtKB=C5XDI3	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb303780\|UniProtKB=A0A804Q7X8	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb095010\|UniProtKB=A0A804MLA4	Zea mays	O
SETIT\|EnsemblGenome=SETIT_028881mg\|UniProtKB=K3ZQK1	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3002G083000\|UniProtKB=C5XDI2	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb095020\|UniProtKB=A0A804MLA7	Zea mays	O
ORYSJ\|EnsemblGenome=Os07g0232900\|UniProtKB=Q8H384	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_1g53670v3\|UniProtKB=I1H2I7	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0509930\|UniProtKB=A0A8I6YJV8	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS5B02G388000\|UniProtKB=W5FIP9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G392700\|UniProtKB=A0A059ZXY5	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G383400\|UniProtKB=A0A060A6L9	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_0057381mg\|UniProtKB=K3XUY1	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3010G250900\|UniProtKB=C5Z8W8	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb226870\|UniProtKB=A0A804U735	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os06g0700700\|UniProtKB=A3BF39	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g34140v3\|UniProtKB=I1GWN6	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0727780\|UniProtKB=A0A8I6YFU9	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS7B02G320900\|UniProtKB=A0A3B6SKA4	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G420000\|UniProtKB=A0A3B6RP12	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G412800\|UniProtKB=A0A3B6TPQ8	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.7HG0727750\|UniProtKB=F2DHJ8	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS7B02G320100\|UniProtKB=A0A060A663	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7A02G419500\|UniProtKB=A0A060A1L0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS7D02G412400\|UniProtKB=A0A060A6M6	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_004276\|UniProtKB=A0A1U8B7Y8	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110778383\|UniProtKB=A0A9R0JL04	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0388061\|UniProtKB=A0A251TX00	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr07g0195411\|UniProtKB=A0A251UBA9	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr10g0455131\|UniProtKB=A0A251TMN3	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr07g0302731\|UniProtKB=A0A9K3NG88	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr09g0372871\|UniProtKB=A0A251TVV2	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C700365000\|UniProtKB=A0A9R1X2T8	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C700364990\|UniProtKB=A0A9R1X037	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C700364980\|UniProtKB=A0A9R1X0J9	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a026280mg\|UniProtKB=A0A022RFF1	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a000994mg\|UniProtKB=A0A022QDM7	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_19221\|UniProtKB=A0A2G2Z133	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc07g009130.3\|UniProtKB=A0A3Q7H7Z9	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107827924\|UniProtKB=A0A1S4DBQ5	Nicotiana tabacum	O
TOBAC\|Gene=LOC107827156\|UniProtKB=A0A1S4D933	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_11s0103g00370\|UniProtKB=D7UBK2	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_C00131\|UniProtKB=A0A059CKB4	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00062157001\|UniProtKB=A0A078HGF6	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00000640001\|UniProtKB=A0A078F6J3	Brassica napus	O
BRACM\|EnsemblGenome=Bra024449\|UniProtKB=M4E6P5	Brassica campestris	O
BRANA\|EnsemblGenome=GSBRNA2T00092809001\|UniProtKB=A0A078JWA4	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00098157001\|UniProtKB=A0A078IJ74	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra038842\|UniProtKB=M4FCM3	Brassica campestris	LDO
GOSHI\|Gene=LOC107954713\|UniProtKB=A0A1U8P3Q3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107907360\|UniProtKB=A0A1U8JNB3	Gossypium hirsutum	O
GOSHI\|Gene=LOC107907509\|UniProtKB=A0A1U8JJD3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_039368\|UniProtKB=A0A061GS34	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g001837mg\|UniProtKB=A0A067F6U1	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_006G076900v3\|UniProtKB=A0A2K1ZYJ4	Populus trichocarpa	LDO
RICCO\|Gene_ORFName=RCOM_0305430\|UniProtKB=B9T1W7	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_17G060400\|UniProtKB=K7MK57	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_13G099600\|UniProtKB=K7LWU0	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g127580\|UniProtKB=G7JUC1	Medicago truncatula	LDO
JUGRE\|Gene=LOC109016287\|UniProtKB=A0A6P9F279	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr11_25720\|UniProtKB=A0A2I4HL72	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_2G060450\|UniProtKB=A0A0A0LJB5	Cucumis sativus	O
CUCSA\|EnsemblGenome=Csa_1G423340\|UniProtKB=A0A076MFR3	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G078700\|UniProtKB=A0A251QU64	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_417746\|UniProtKB=D8S3H3	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_422158\|UniProtKB=D8SHI8	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_425782\|UniProtKB=D8SUA1	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_417745\|UniProtKB=D8S3H2	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_149298\|UniProtKB=D8RRX0	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_60724\|UniProtKB=D8RIV6	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_104244\|UniProtKB=D8RY19	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_118425\|UniProtKB=D8SJM4	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_60690\|UniProtKB=D8QRZ3	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_89397\|UniProtKB=D8RBL1	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c2_8660\|UniProtKB=A0A2K1L0Q5	Physcomitrella patens	LDO
PHYPA\|EnsemblGenome=Pp3c6_24750\|UniProtKB=A0A2K1KH08	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0019s0084\|UniProtKB=A0A2R6XF21	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001360120\|UniProtKB=A0A1Y1HWV0	Klebsormidium nitens	LDO
METAC\|EnsemblGenome=MA_3632\|UniProtKB=Q8TJZ4	Methanosarcina acetivorans	LDO
HALSA\|EnsemblGenome=VNG_0149G\|UniProtKB=Q9HSN5	Halobacterium salinarum	LDO
CHLAA\|EnsemblGenome=Caur_0868\|UniProtKB=A9WH06	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO0164\|UniProtKB=Q9RJ01	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv1992c\|UniProtKB=P9WPS7	Mycobacterium tuberculosis	LDO
CLOBH\|Gene_OrderedLocusName=CBO0478\|UniProtKB=A5HZ22	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr1911\|UniProtKB=Q8DN51	Streptococcus pneumoniae	LDO
LISMO\|EnsemblGenome=CAC99178\|UniProtKB=P58414	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_33490\|UniProtKB=O32219	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_0596\|UniProtKB=Q81I26	Bacillus cereus	LDO
DEIRA\|EnsemblGenome=DR_A0073\|UniProtKB=Q9RZ81	Deinococcus radiodurans	LDO
SYNY3\|EnsemblGenome=BAA10707\|UniProtKB=Q59998	Synechocystis	LDO
BACTN\|EnsemblGenome=BT_2512\|UniProtKB=Q8A4T5	Bacteroides thetaiotaomicron	LDO
RHOBA\|EnsemblGenome=RB4891\|UniProtKB=Q7UH21	Rhodopirellula baltica	LDO
FUSNN\|EnsemblGenome=FN0258\|UniProtKB=Q8RGN3	Fusobacterium nucleatum	LDO
HELPY\|EnsemblGenome=HP_0791\|UniProtKB=Q59465	Helicobacter pylori	LDO
GEOSL\|EnsemblGenome=GSU2147\|UniProtKB=Q74B94	Geobacter sulfurreducens	LDO
VIBCH\|EnsemblGenome=VC_1033\|UniProtKB=Q9KT72	Vibrio cholerae	LDO
PSEAE\|EnsemblGenome=PA2435\|UniProtKB=Q9I147	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA3690\|UniProtKB=Q9HXV0	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM3576\|UniProtKB=Q8ZLE5	Salmonella typhimurium	LDO
YERPE\|Gene_OrderedLocusName=YPO3820\|UniProtKB=A0A5P8YB25	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAE77824\|UniProtKB=P37617	Escherichia coli	LDO