PANTHER Gene Information

Gene Symbol(s):

FPGS2

Organism:

Arabidopsis thaliana

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Gene Name:

Folylpolyglutamate synthase

Gene ID:

2100048

Protein ID:

F4J2K2

Persistent Id:

PTN000124065

Alternate Ids:

FPGS2_ARATH(UniProtKB-ID)	DHFS-FPGS homolog C {ECO:0000312\|EMBL:AEE74866.1}(Synonym)
820179(GeneID)	Q9SR80(AltAccession)
locus:2100048(TAIR)	AT3G10160(Ensembl_PRO)
AT3G10160(Ensembl_TRS)	FPGS2{ECO:0000303\|PubMed:21070407}(Symbol)
AEE74866(EMBL-CDS)	CP002686(EMBL)
363579869(GI)	AT3G10160(Ensembl)
NM_111851(refSeq)	6.3.2.17 {ECO:0000269\|PubMed:11752472}(EC)
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PANTHER Classification

PANTHER Family:	FOLYLPOLYGLUTAMATE SYNTHASE-RELATED (PTHR11136)
PANTHER Subfamily:	FOLYLPOLYGLUTAMATE SYNTHASE, MITOCHONDRIAL (PTHR11136:SF5)
PANTHER GO-slim Molecular Function:	ligase activity
PANTHER GO-slim Biological Process:	organonitrogen compound biosynthetic process organic cyclic compound biosynthetic process cellular nitrogen compound biosynthetic process aromatic compound biosynthetic process heterocycle biosynthetic process folic acid-containing compound metabolic process
PANTHER GO-slim Cellular Component:	cytosol mitochondrion
PANTHER protein class:	ligase

Pathway Categories:

Tetrahydrofolate biosynthesis

Dihydrofolate synthase

Formyltetrahydrofolate biosynthesis

Dihydrofolate synthase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	tetrahydrofolylpolyglutamate synthase activity
GO BP Complete:	photorespiration, seedling development, tetrahydrofolylpolyglutamate biosynthetic process, one-carbon metabolic process
GO CC Complete:	cytoplasm, mitochondrial matrix, mitochondrion, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3824\|UniProtKB=Q05932	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000021399.5\|UniProtKB=K7BAH4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000000943.3\|UniProtKB=G3QF64	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000018506.4\|UniProtKB=A0A1D5R296	Macaca mulatta	LDO
MOUSE\|MGI=MGI=95576\|UniProtKB=P48760	Mus musculus	LDO
RAT\|RGD=1587713\|UniProtKB=M0R401	Rattus norvegicus	LDO
BOVIN\|Gene=FPGS\|UniProtKB=A6H751	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000008994.6\|UniProtKB=F1MWN5	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000005626.5\|UniProtKB=F1RS02	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000013074.4\|UniProtKB=A0A5F5PQA7	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000001488.5\|UniProtKB=A0A337ST19	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845005346.1\|UniProtKB=A0A8I3MXH3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000005594.3\|UniProtKB=F7DJU5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000008391.4\|UniProtKB=F6XLU7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010028091.1\|UniProtKB=A0A8V1AJ93	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000015606.3\|UniProtKB=A0A803TCN2	Anolis carolinensis	LDO
XENLA\|Gene=fpgs.S\|UniProtKB=A0A1L8F1L6	Xenopus laevis	O
XENLA\|Gene=fpgs.L\|UniProtKB=A0A8J1LI43	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-1003162\|UniProtKB=A4IIL7	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000018278.2\|UniProtKB=H2MVP5	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-2781\|UniProtKB=F1Q7N0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005327.1\|UniProtKB=W5MDF7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004096.3\|UniProtKB=F6YHL8	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000002123.3\|UniProtKB=F6WRV9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118421641\|UniProtKB=A0A9J7LLU4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC105445392\|UniProtKB=A0A7M7MYJ5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC584857\|UniProtKB=A0A7M7RCW9	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100890414\|UniProtKB=A0A7M7SSU5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115929174\|UniProtKB=A0A7M7PM37	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC588460\|UniProtKB=A0A7M7TGZ3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592205\|UniProtKB=A0A7M7HNC2	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00017777\|UniProtKB=Q09509	Caenorhabditis elegans	LDO
PRIPA\|EnsemblGenome=WBGene00304270\|UniProtKB=A0A8R1V1Z3	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0051773\|UniProtKB=Q9VQW0	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0030407\|UniProtKB=Q9VYL1	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004679\|UniProtKB=Q5TSB4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC000540\|UniProtKB=D6W9Q8	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_205741\|UniProtKB=E9FT03	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW006911\|UniProtKB=B7PVJ7	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG64438\|UniProtKB=T1FXU9	helobdella robusta	LDO
TRIAD\|EnsemblGenome=TriadG53217\|UniProtKB=B3RNM4	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_28582\|UniProtKB=A9V8L2	Monosiga brevicollis	LDO
YEAST\|SGD=S000005767\|UniProtKB=Q08645	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ACR134W\|UniProtKB=Q75BY6	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000187593\|UniProtKB=A0A1D8PH56	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E24497g\|UniProtKB=Q6C4Q7	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_03840\|UniProtKB=Q5B6J0	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G09440\|UniProtKB=Q4WML8	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_8G04160\|UniProtKB=Q4WCJ9	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_4G08060\|UniProtKB=Q4WP52	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU00893\|UniProtKB=Q7SFD9	Neurospora crassa	O
NEUCR\|EnsemblGenome=NCU00892\|UniProtKB=O13492	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_04298\|UniProtKB=A7EG57	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_07273\|UniProtKB=A7EPM4	Sclerotinia sclerotiorum	O
SCLS1\|EnsemblGenome=SS1G_04299\|UniProtKB=A7EG58	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_00842\|UniProtKB=Q0V572	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC1709.17\|UniProtKB=O74742	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_03224\|UniProtKB=B6K3N4	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC04840\|UniProtKB=Q5KJZ3	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_03772\|UniProtKB=A0A0D1CNF1	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_17179\|UniProtKB=E3L2Y2	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_9940\|UniProtKB=F4NXV7	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0292632\|UniProtKB=Q54CY5	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_77507\|UniProtKB=F0ZGT5	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_36_2610\|UniProtKB=Q4Q1G0	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.6k15.3140\|UniProtKB=Q38AL2	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_229870\|UniProtKB=A2G107	Trichomonas vaginalis	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_bd460\|UniProtKB=B8LEL5	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GHG7_PHYRM\|UniProtKB=H3GHG7	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_05g239100v5\|UniProtKB=A0A2K3DT30	Chlamydomonas reinhardtii	LDO
CHLRE\|EnsemblGenome=CHLRE_05g239067v5\|UniProtKB=A0A2K3DT28	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00053p00158610\|UniProtKB=W1PDH1	Amborella trichopoda	LDO
MUSAM\|EnsemblGenome=Ma01_g05040\|UniProtKB=A0A804HQF5	Musa acuminata subsp. malaccensis	LDO
NELNU\|Gene=LOC104589593\|UniProtKB=A0A1U7YZY5	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110792990\|UniProtKB=A0A9R0IQA9	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr10g0435881\|UniProtKB=A0A9K3N433	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C900467570\|UniProtKB=A0A9R1UHU4	Lactuca sativa	LDO
CAPAN\|EnsemblGenome=T459_13614\|UniProtKB=A0A1U8GL32	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc04g016550.3\|UniProtKB=A0A3Q7GSV2	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107801609\|UniProtKB=A0A1S4AV50	Nicotiana tabacum	O
TOBAC\|Gene=LOC107777926\|UniProtKB=A0A1S3YNJ5	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi08g01694\|UniProtKB=F6HLM9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_A02294\|UniProtKB=A0A059DHQ7	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00018643001\|UniProtKB=A0A078GBZ5	Brassica napus	O
BRANA\|Gene_ORFName=GSBRNA2T00072874001\|UniProtKB=A0A078HX34	Brassica napus	LDO
THECC\|EnsemblGenome=TCM_024488\|UniProtKB=A0A061F3L1	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_016G041800v3\|UniProtKB=A0A2K1XAJ0	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_006G045400v3\|UniProtKB=A0A2K1ZWQ5	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_09G016200\|UniProtKB=A0A251K398	Manihot esculenta	LDO
MANES\|EnsemblGenome=MANES_08G053400\|UniProtKB=A0A2C9VDM0	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0255180\|UniProtKB=B9SVS7	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_10G105400\|UniProtKB=K7LIJ3	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_02G191500\|UniProtKB=I1JGE2	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g051385\|UniProtKB=A0A072VHI5	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr04_18410\|UniProtKB=A0A2I4GJD9	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr04_18400\|UniProtKB=A0A2I4GJD5	Juglans regia	LDO
JUGRE\|EnsemblGenome=Jr03_05270\|UniProtKB=A0A2I4ECS0	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_3G823100\|UniProtKB=A0A0A0LHM9	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_7G049800\|UniProtKB=A0A251N6W1	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_229276\|UniProtKB=D8SVL1	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_75567\|UniProtKB=D8QMQ9	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_402687\|UniProtKB=D8QMQ8	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_234236\|UniProtKB=D8SJ46	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_86713\|UniProtKB=D8R7G7	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_32076\|UniProtKB=D8RVZ6	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c23_670\|UniProtKB=A0A2K1IHQ1	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c24_9100\|UniProtKB=A9TAU6	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0010s0086\|UniProtKB=A0A2R6XKP2	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001580250\|UniProtKB=A0A1Y1I3F7	Klebsormidium nitens	LDO
CHLAA\|EnsemblGenome=Caur_0436\|UniProtKB=A9WDT0	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO2614\|UniProtKB=Q9L1G4	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=LH57_13380\|UniProtKB=I6Y0R5	Mycobacterium tuberculosis	O
CLOBH\|Gene_OrderedLocusName=CBO3163\|UniProtKB=A5I6P2	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr0267\|UniProtKB=Q8DR92	Streptococcus pneumoniae	O
STRR6\|EnsemblGenome=spr0178\|UniProtKB=Q8DRE0	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_01766\|UniProtKB=Q2FXR9	Staphylococcus aureus	O
LISMO\|Gene=folC\|UniProtKB=Q8Y6Y0	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_28080\|UniProtKB=Q05865	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4464\|UniProtKB=Q817R7	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_0166\|UniProtKB=Q9WY13	Thermotoga maritima	O
DEIRA\|EnsemblGenome=DR_0340\|UniProtKB=Q9RXH3	Deinococcus radiodurans	O
GLOVI\|Gene=folC\|UniProtKB=Q7NLP7	Gloeobacter violaceus	O
SYNY3\|Gene=folC\|UniProtKB=P73842	Synechocystis	O
LEPIN\|EnsemblGenome=LA_0637\|UniProtKB=Q8F8C1	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_1335\|UniProtKB=Q8A839	Bacteroides thetaiotaomicron	O
RHOBA\|EnsemblGenome=RB6237\|UniProtKB=Q7UQM1	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_2045\|UniProtKB=O67833	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A0558\|UniProtKB=B5YJI6	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_0758\|UniProtKB=B8DZV7	Dictyoglomus turgidum	O
FUSNN\|EnsemblGenome=FN1014\|UniProtKB=Q8RES8	Fusobacterium nucleatum	O
HELPY\|EnsemblGenome=HP_1545\|UniProtKB=O26070	Helicobacter pylori	O
NEIMB\|EnsemblGenome=NMB0693\|UniProtKB=Q9K0C1	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU2368\|UniProtKB=Q74AI6	Geobacter sulfurreducens	O
BRADU\|Gene=folC\|UniProtKB=Q89WE2	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_0894\|UniProtKB=Q83D50	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_1261\|UniProtKB=P43775	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_3067\|UniProtKB=Q8ECR5	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_1001\|UniProtKB=Q9KTA2	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC0950\|UniProtKB=Q8PC05	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA3111\|UniProtKB=Q9HZA8	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM2365\|UniProtKB=Q8ZNC0	Salmonella typhimurium	O
YERPE\|Gene_OrderedLocusName=YPO2769\|UniProtKB=A0A5P8YIK0	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAA16164\|UniProtKB=P08192	Escherichia coli	O