PANTHER Gene Information

Gene Symbol(s):

MDH2

Organism:

Arabidopsis thaliana

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Gene Name:

Malate dehydrogenase 2, cytoplasmic

Gene ID:

2176441

Protein ID:

P57106

Persistent Id:

PTN000600427

Alternate Ids:

MDHC2_ARATH(UniProtKB-ID)	MDHC2(Synonym)
Q8LA78(AltAccession)	219789573(GI)
MDH2(Symbol)	NP_199147(refSeq)
CP002688(EMBL)	AT5G43330(Ensembl_TRS)
BAA97412(EMBL-CDS)	AT5G43330(Ensembl)
834351(GeneID)	1.1.1.37(EC)
locus:2176441(TAIR)	AT5G43330(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	MALATE DEHYDROGENASE (PTHR23382)
PANTHER Subfamily:	MALATE DEHYDROGENASE, CYTOPLASMIC (PTHR23382:SF3)
PANTHER GO-slim Molecular Function:	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
PANTHER GO-slim Biological Process:	nicotinamide nucleotide metabolic process tricarboxylic acid cycle dicarboxylic acid metabolic process purine nucleotide metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	dehydrogenase

Pathway Categories:

TCA cycle

Malate Dehydrogenase

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	L-malate dehydrogenase (NAD+) activity, protein binding
GO BP Complete:	oxaloacetate metabolic process, NADH metabolic process, malate metabolic process, tricarboxylic acid cycle
GO CC Complete:	plasmodesma, cytoplasm, cytosol, plasma membrane, plastid

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=17836\|UniProtKB=Q5I0G3	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000012847.6\|UniProtKB=H2R671	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002059.3\|UniProtKB=G3QI31	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000017734.4\|UniProtKB=F7AU42	Macaca mulatta	O
MOUSE\|MGI=MGI=1923918\|UniProtKB=Q5F204	Mus musculus	O
RAT\|RGD=1307874\|UniProtKB=A0A0G2JVU8	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000016192\|UniProtKB=A3KMX7	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000016133.5\|UniProtKB=A0A287AW19	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000007491.3\|UniProtKB=A0A3Q2H942	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000015372.6\|UniProtKB=M3WMH0	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845021551.1\|UniProtKB=A0A8I3P8B1	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000016001.4\|UniProtKB=F7EYX5	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000000659.3\|UniProtKB=F6RFW3	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010025874.1\|UniProtKB=E1BQM3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000009563.4\|UniProtKB=H9GFC6	Anolis carolinensis	O
XENLA\|Gene=mdh1b.L\|UniProtKB=A0A1L8EWZ9	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-954834\|UniProtKB=A0A6I8PWZ6	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000005272.2\|UniProtKB=H2LKU0	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-060929-384\|UniProtKB=Q08BZ4	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010397.1\|UniProtKB=W5MWJ0	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000016548.2\|UniProtKB=F6VGB1	Ciona intestinalis	O
BRAFL\|Gene=MDH1B\|UniProtKB=Q8T773	Branchiostoma floridae	O
BRAFL\|Gene=LOC118403379\|UniProtKB=A0A9J7HIR8	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC588960\|UniProtKB=A0A7M7RDV8	Strongylocentrotus purpuratus	O
TRICA\|EnsemblGenome=TC015467\|UniProtKB=D2A536	Tribolium castaneum	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g90973\|UniProtKB=A7RRY2	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG31069\|UniProtKB=B3S8Q1	Trichoplax adhaerens	O
HUMAN\|HGNC=6970\|UniProtKB=P40925	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000011974.5\|UniProtKB=A0A2I3RZV0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000007085.3\|UniProtKB=G3QVZ2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000006163.4\|UniProtKB=A0A1D5Q3Q0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97051\|UniProtKB=P14152	Mus musculus	LDO
RAT\|RGD=3072\|UniProtKB=O88989	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000019295\|UniProtKB=Q3T145	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000025751\|UniProtKB=P11708	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000010849.4\|UniProtKB=A0A9L0S5Z4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000024183\|UniProtKB=Q7YRU4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845019026.1\|UniProtKB=A0A8I3P822	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000003073.2\|UniProtKB=F6PLH7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000012426.4\|UniProtKB=F7DK14	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000005865.4\|UniProtKB=G1KET7	Anolis carolinensis	LDO
XENLA\|Gene=mdh1.S\|UniProtKB=A0A8J0QHB2	Xenopus laevis	LDO
XENLA\|Gene=mdh1.L\|UniProtKB=A0A8J0QHL7	Xenopus laevis	O
XENLA\|Gene=mdh1\|UniProtKB=Q6PAB3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-484872\|UniProtKB=Q6DIY9	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000002524.2\|UniProtKB=Q801E7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-7655\|UniProtKB=Q7ZSY2	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000002906.2\|UniProtKB=A0A3B3IGP1	Oryzias latipes	LDO
DANRE\|Gene=mdh1aa\|UniProtKB=A0A8M1P861	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016063.1\|UniProtKB=W5NGN7	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000020754.1\|UniProtKB=H2Y3K9	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118417865\|UniProtKB=A0A9J7LBV1	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC591635\|UniProtKB=A0A7M7HNY4	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00018491\|UniProtKB=Q9UAV5	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00038253\|UniProtKB=A8XUF7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00279005\|UniProtKB=A0A2A6C4B8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00118357\|UniProtKB=A0A2A6CAB5	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0262782\|UniProtKB=Q9VKX2	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP009510\|UniProtKB=A0A1S4H1C6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC008177\|UniProtKB=D2A083	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_308915\|UniProtKB=E9HA96	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW021953\|UniProtKB=B7QAS6	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW007624\|UniProtKB=B7PRH2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG193969\|UniProtKB=T1FVI7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG168229\|UniProtKB=T1F0C2	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG186114\|UniProtKB=T1FNN9	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g185681\|UniProtKB=A7S4V3	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG63987\|UniProtKB=B3S0L5	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_39154\|UniProtKB=A9VCK2	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_15806\|UniProtKB=A9UV42	Monosiga brevicollis	LDO
ENTH1\|Gene_ORFName=EHI_067860\|UniProtKB=A0A8U0WPL4	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_152670\|UniProtKB=C4LSV1	Entamoeba histolytica	LDO
ENTH1\|Gene_ORFName=EHI_030810\|UniProtKB=A0A8U0WPY4	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0290207\|UniProtKB=Q54GE6	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_91907\|UniProtKB=F0ZJ23	Dictyostelium purpureum	LDO
DICDI\|dictyBase=DDB_G0280255\|UniProtKB=Q54VM2	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_76668\|UniProtKB=F0ZEA3	Dictyostelium purpureum	O
PARTE\|EnsemblGenome=GSPATT00010909001\|UniProtKB=A0CVC4	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00033909001\|UniProtKB=A0C0W6	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022468001\|UniProtKB=A0E1Y0	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00032410001\|UniProtKB=A0BUG1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00014396001\|UniProtKB=A0D8T3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00036328001\|UniProtKB=A0C8S6	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPS_41425\|UniProtKB=B5YNR1	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G9V6_PHYRM\|UniProtKB=H3G9V6	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_02g145800v5\|UniProtKB=A0A2K3E3Q0	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00106p00146860\|UniProtKB=W1NZP0	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_32G00170\|UniProtKB=A0A0K9P894	Zostera marina	LDO
ZOSMR\|Gene_ORFName=ZOSMA_445G00060\|UniProtKB=A0A0K9P153	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma05_g03680\|UniProtKB=A0A804J0I8	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma04_g28520\|UniProtKB=A0A804IUY5	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_036550mg\|UniProtKB=K4ACE3	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3001G219300\|UniProtKB=C5WYF2	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb221790\|UniProtKB=A0A804PAV9	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb045790\|UniProtKB=Q08062	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os10g0478200\|UniProtKB=Q7XDC8	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g28820v3\|UniProtKB=I1I4Q0	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0043190\|UniProtKB=F2D4W6	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1B02G172400\|UniProtKB=A3KLL4	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS1A02G155200\|UniProtKB=A0A3B5XY18	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G153900\|UniProtKB=A0A3B5ZSR0	Triticum aestivum	LDO
NELNU\|Gene=LOC104610015\|UniProtKB=A0A1U8B244	Nelumbo nucifera	O
NELNU\|Gene=LOC104600872\|UniProtKB=A0A1U8AJC1	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110787385\|UniProtKB=A0A9R0IEH0	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0612031\|UniProtKB=A0A251SX18	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr03g0135421\|UniProtKB=A0A251VCJ8	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C300149290\|UniProtKB=A0A9R1W760	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a009775mg\|UniProtKB=A0A022PVP8	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_07792\|UniProtKB=A0A1U8G3L8	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400017170\|UniProtKB=M1BFT7	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc09g090140.3\|UniProtKB=A0A3Q7I7B3	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107772922\|UniProtKB=A0A1S3Y6M1	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107773752\|UniProtKB=A0A1S3Y9D7	Nicotiana tabacum	O
TOBAC\|Gene=LOC107763505\|UniProtKB=A0A1S3XCK8	Nicotiana tabacum	O
TOBAC\|Gene=MD1\|UniProtKB=Q9FSF0	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107810010\|UniProtKB=A0A1S4BMX4	Nicotiana tabacum	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_H03047\|UniProtKB=A0A059B357	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C09P25710.1\|UniProtKB=A0A078I1Y7	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A09P20330.1\|UniProtKB=A0A078H7S5	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra027485\|UniProtKB=M4EFC3	Brassica campestris	LDO
GOSHI\|Gene=LOC107940531\|UniProtKB=D2D318	Gossypium hirsutum	O
GOSHI\|Gene=LOC107936241\|UniProtKB=A0A1U8MFT2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107897068\|UniProtKB=A0A1U8IPW6	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_020890\|UniProtKB=A0A061EMF9	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g020022mg\|UniProtKB=A0A067EQX8	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_008G166800v3\|UniProtKB=A9P8R3	Populus trichocarpa	O
RICCO\|Gene_ORFName=RCOM_0400230\|UniProtKB=B9T5E3	Ricinus communis	O
POPTR\|EnsemblGenome=POPTR_010G071000v3\|UniProtKB=A0A2K1YQ82	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_03G164100\|UniProtKB=A0A2C9W9K2	Manihot esculenta	LDO
MANES\|EnsemblGenome=MANES_15G040800\|UniProtKB=A0A2C9UCS2	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0400340\|UniProtKB=B9T5E4	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_02G005500\|UniProtKB=A0A0R4J2L9	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_10G006500\|UniProtKB=H2D5S3	Glycine max	O
MEDTR\|EnsemblGenome=MTR_1g043040\|UniProtKB=B7FJQ4	Medicago truncatula	LDO
MEDTR\|EnsemblGenome=MTR_1g076130\|UniProtKB=A0A072VMC4	Medicago truncatula	LDO
JUGRE\|Gene=LOC108982433\|UniProtKB=A0A6P9ELH1	Juglans regia	O
JUGRE\|EnsemblGenome=Jr07_23210\|UniProtKB=A0A2I4DKI1	Juglans regia	O
JUGRE\|EnsemblGenome=Jr12_14540\|UniProtKB=A0A2I4DM54	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_2G174150\|UniProtKB=A0A0A0LII5	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G039300\|UniProtKB=M5Y9C1	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_271992\|UniProtKB=D8SY75	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_421109\|UniProtKB=D8SE66	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_269798\|UniProtKB=D8T711	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c21_10840\|UniProtKB=A9TI25	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0206s0010\|UniProtKB=A0A2R6W0E4	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_002600190\|UniProtKB=A0A1Y1I9W7	Klebsormidium nitens	LDO
STRCO\|Gene_OrderedLocusName=SCO4827\|UniProtKB=Q9K3J3	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv1240\|UniProtKB=P9WK13	Mycobacterium tuberculosis	O
DEIRA\|EnsemblGenome=DR_0325\|UniProtKB=Q9RXI8	Deinococcus radiodurans	O
LEPIN\|EnsemblGenome=LA_2139\|UniProtKB=Q8F4A2	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_2510\|UniProtKB=Q8A4T7	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_376\|UniProtKB=O84381	Chlamydia trachomatis	O
COXBU\|EnsemblGenome=CBU_1241\|UniProtKB=Q83C87	Coxiella burnetii	O
XANCP\|EnsemblGenome=XCC0928\|UniProtKB=Q8PC25	Xanthomonas campestris	O