PANTHER Gene Information

Gene Symbol(s):

bna5-2

Organism:

Neosartorya fumigata

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Gene Name:

Kynureninase 2

Gene ID:

AFUA_4G09840

Protein ID:

Q4WPN0

Persistent Id:

PTN002679540

Alternate Ids:

L-kynurenine hydrolase 2 {ECO:0000255\|HAMAP-Rule:MF_03017}(Synonym)	EAL89804(Ensembl_PRO)
EAL89804(Ensembl_TRS)	bna5-2(Symbol)
AAHF01000005(EMBL)	EAL89804(EMBL-CDS)
70993990(GI)	AFUA_4G09840(Ensembl)
XP_751842(refSeq)	KYNU2_ASPFU(UniProtKB-ID)
3509348(GeneID)	3.7.1.3 {ECO:0000255\|HAMAP-Rule:MF_03017}(EC)
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PANTHER Classification

PANTHER Family:	KYNURENINASE (PTHR14084)
PANTHER Subfamily:	KYNURENINASE 2 (PTHR14084:SF2)
PANTHER GO-slim Molecular Function:	hydrolase activity
PANTHER GO-slim Biological Process:	monocarboxylic acid metabolic process amino acid catabolic process biogenic amine metabolic process aromatic amino acid family catabolic process alpha-amino acid metabolic process heterocycle catabolic process cellular nitrogen compound catabolic process
PANTHER GO-slim Cellular Component:	cytoplasm
PANTHER protein class:	hydrolase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	pyridoxal phosphate binding, kynureninase activity, hydrolase activity
GO BP Complete:	tryptophan catabolic process, quinolinate biosynthetic process, 'de novo' NAD biosynthetic process from tryptophan, tryptophan catabolic process to kynurenine, pyridine nucleotide biosynthetic process, NAD biosynthetic process, anthranilate metabolic process, L-kynurenine catabolic process
GO CC Complete:	cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6469\|UniProtKB=Q16719	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000012509.7\|UniProtKB=H2QIS6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000007406.3\|UniProtKB=G3RXV2	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000021330.4\|UniProtKB=F6URB1	Macaca mulatta	O
MOUSE\|MGI=MGI=1918039\|UniProtKB=Q9CXF0	Mus musculus	O
RAT\|RGD=71061\|UniProtKB=P70712	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000032277.4\|UniProtKB=F1MCH2	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000015673.5\|UniProtKB=F1S0H1	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000018188.4\|UniProtKB=A0A3Q2KVR2	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000018501.5\|UniProtKB=A0A5F5XMX8	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845013520.1\|UniProtKB=A0A8I3S055	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000002997.3\|UniProtKB=F6Q3X0	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000045440.1\|UniProtKB=A0A6I8P7W7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010009338.1\|UniProtKB=A0A8V0Y375	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000003164.4\|UniProtKB=A0A803TNS6	Anolis carolinensis	O
XENLA\|Gene=kynu.L\|UniProtKB=A0A1L8EVT8	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000032399\|UniProtKB=A0A6I8PXQ1	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000005074.2\|UniProtKB=H2LK45	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-120215-204\|UniProtKB=A0A0R4IQY2	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000001250.1\|UniProtKB=W5LZ66	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000017067.2\|UniProtKB=F7A2G6	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000019860.1\|UniProtKB=H2XYS1	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000024316.1\|UniProtKB=H2XXH7	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000024622.1\|UniProtKB=H2XQ19	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000018272.1\|UniProtKB=H2XP90	Ciona intestinalis	O
BRAFL\|Gene=LOC118418061\|UniProtKB=A0A9J7MUV8	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC754267\|UniProtKB=A0A7M7N130	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00015802\|UniProtKB=Q18026	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00035224\|UniProtKB=A8XKT0	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00117862\|UniProtKB=A0A2A6B7D8	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00117054\|UniProtKB=A0A2A6CK34	Pristionchus pacificus	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_310889\|UniProtKB=E9FVX1	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW005441\|UniProtKB=B7PL61	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG188733\|UniProtKB=T1FQB2	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g235255\|UniProtKB=A7SCH8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG58136\|UniProtKB=B3S0Z1	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG28018\|UniProtKB=B3S0Z2	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_26773\|UniProtKB=A9V3C0	Monosiga brevicollis	O
YEAST\|SGD=S000004221\|UniProtKB=Q05979	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AGL098W\|UniProtKB=Q750P5	Eremothecium gossypii	O
CANAL\|CGD=CAL0000197943\|UniProtKB=Q59QC4	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B22902g\|UniProtKB=Q6CDM0	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_01857\|UniProtKB=Q5BC73	Emericella nidulans	LDO
NEUCR\|EnsemblGenome=NCU09183\|UniProtKB=Q7S332	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_08223\|UniProtKB=A7ESB8	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_02814\|UniProtKB=Q0UZK0	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CNC03980\|UniProtKB=P0CO52	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_04846\|UniProtKB=A0A0D1DQV3	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_18997\|UniProtKB=E3L8V9	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_33380\|UniProtKB=F4P5P7	Batrachochytrium dendrobatidis	O
DICDI\|dictyBase=DDB_G0284203\|UniProtKB=Q54Q04	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_74692\|UniProtKB=F0Z8G9	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_26_2240\|UniProtKB=Q4Q8W8	Leishmania major	O
TRYB2\|Gene_ORFName=Tb09.160.0810\|UniProtKB=Q38FV7	Trypanosoma brucei	O
KLENI\|Gene_ORFName=KFL_001940090\|UniProtKB=A0A1Y1I3M4	Klebsormidium nitens	O
HALSA\|EnsemblGenome=VNG_0915G\|UniProtKB=Q9HR11	Halobacterium salinarum	O
CHLAA\|EnsemblGenome=Caur_1258\|UniProtKB=A9WK35	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO3645\|UniProtKB=Q9X8R2	Streptomyces coelicolor	O
DEIRA\|EnsemblGenome=DR_A0338\|UniProtKB=Q9RYH5	Deinococcus radiodurans	O
BRADU\|Gene=kynU\|UniProtKB=Q89MN3	Bradyrhizobium diazoefficiens	O
PSEAE\|EnsemblGenome=PA2080\|UniProtKB=Q9I235	Pseudomonas aeruginosa	O