PANTHER Gene Information

Gene Symbol(s):

PPARG

Organism:

Bos taurus

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Gene Name:

Peroxisome proliferator-activated receptor gamma

Gene ID:

ENSBTAG00000001333

Protein ID:

O18971

Persistent Id:

PTN002377499

Alternate Ids:

Y12419(EMBL)	94534932(GI)
Nuclear receptor subfamily 1 group C member 3(Synonym)	PPARG(Symbol)
CAA73033(EMBL-CDS)	281993(GeneID)
Q1LZB7(AltAccession)	ENSBTAG00000001333(Ensembl)
PPARG_BOVIN(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	NUCLEAR HORMONE RECEPTOR (PTHR24082)
PANTHER Subfamily:	PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA (PTHR24082:SF488)
PANTHER GO-slim Molecular Function:	DNA-binding transcription repressor activity, RNA polymerase II-specific RNA polymerase II cis-regulatory region sequence-specific DNA binding signaling receptor activity
PANTHER GO-slim Biological Process:	negative regulation of transcription by RNA polymerase II negative regulation of inflammatory response regulation of lipid metabolic process cell differentiation regulation of localization fatty acid metabolic process hormone-mediated signaling pathway positive regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	C4 zinc finger nuclear receptor

Pathway Categories:

CCKR signaling map

PPARgamma

Gonadotropin-releasing hormone receptor pathway

PPARalpha/gamma

Gonadotropin-releasing hormone receptor pathway

PPARgamma

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, DNA-binding transcription factor activity, zinc ion binding, nuclear receptor activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, transcription cis-regulatory region binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, chromatin binding, E-box binding
GO BP Complete:	negative regulation of inflammatory response, regulation of DNA-templated transcription, regulation of fat cell differentiation, regulation of circadian rhythm, positive regulation of transcription by RNA polymerase II, positive regulation of fatty acid metabolic process, fatty acid metabolic process, regulation of transcription by RNA polymerase II, hormone-mediated signaling pathway, negative regulation of transcription by RNA polymerase II, epithelial cell differentiation, cellular response to insulin stimulus, retinoic acid receptor signaling pathway, negative regulation of DNA-templated transcription, rhythmic process, positive regulation of DNA-templated transcription, cell fate commitment, cell differentiation, negative regulation of cholesterol storage, peroxisome proliferator activated receptor signaling pathway
GO CC Complete:	nucleus, cytoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Nuclear Receptor transcription pathway, Generic Transcription Pathway, Gene expression (Transcription), RNA Polymerase II Transcription, Transcriptional regulation of white adipocyte differentiation, Developmental Biology

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9236\|UniProtKB=P37231	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014632.7\|UniProtKB=A0A2I3SI31	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000013117.3\|UniProtKB=A0A2I2YCE9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000007191\|UniProtKB=O18924	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97747\|UniProtKB=P37238	Mus musculus	LDO
RAT\|RGD=3371\|UniProtKB=O88275	Rattus norvegicus	LDO
HORSE\|Ensembl=ENSECAG00000016664.4\|UniProtKB=F6Z3I2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006231.6\|UniProtKB=A0A337SSZ2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845029007.1\|UniProtKB=A0A8I3QRC2	Canis lupus familiaris	LDO
CANLF\|Gene=PPARG\|UniProtKB=Q4U3Q4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006233.4\|UniProtKB=F7FS17	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000046286.1\|UniProtKB=A0A6I8NLY2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010027917.1\|UniProtKB=A0A8V1ADV5	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000013360.4\|UniProtKB=G1KNP4	Anolis carolinensis	LDO
XENLA\|Gene=PPARg\|UniProtKB=Q6PA31	Xenopus laevis	O
XENLA\|Gene=pparg\|UniProtKB=P37234	Xenopus laevis	O
XENLA\|Gene=pparg.S\|UniProtKB=A0A8J1KKI4	Xenopus laevis	LDO
XENTR\|Gene=pparg\|UniProtKB=A0A8J1JJG3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000004432.2\|UniProtKB=A0A3B3HYE1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-990415-213\|UniProtKB=A6XMH6	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013954.1\|UniProtKB=W5N992	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000013188.2\|UniProtKB=Q4H2X6	Ciona intestinalis	O
BRAFL\|Gene=LOC118405726\|UniProtKB=A0A9J7HKH0	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC579208\|UniProtKB=A0A7M7RDK4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC576339\|UniProtKB=A0A7M7NVX1	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00003601\|UniProtKB=Q10902	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG04060\|UniProtKB=A8WW43	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003606\|UniProtKB=Q20765	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00028390\|UniProtKB=A8X108	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00004786\|UniProtKB=P41830	Caenorhabditis elegans	O
CAEBR\|WormBase=WBGene00038735\|UniProtKB=A8XVU5	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG19536\|UniProtKB=A8XVU6	Caenorhabditis briggsae	O
CAEBR\|Gene_ORFName=CBG17178\|UniProtKB=A8XQM1	Caenorhabditis briggsae	O
CAEEL\|WormBase=WBGene00003675\|UniProtKB=Q9XUK7	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG13679\|UniProtKB=A8XIG9	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029816\|UniProtKB=A8X5D8	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00272173\|UniProtKB=A0A2A6BTX7	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0000568\|UniProtKB=P13055	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP029560\|UniProtKB=A0A453Z0D2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003935\|UniProtKB=D6WHQ0	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031236\|UniProtKB=A0A139WCF5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_205205\|UniProtKB=E9FSB9	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW020016\|UniProtKB=B7Q233	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG81466\|UniProtKB=T1G4E6	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67484\|UniProtKB=T1FZ14	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG67463\|UniProtKB=T1FZ12	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g108851\|UniProtKB=A7S8G8	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g101676\|UniProtKB=A7S286	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g152310\|UniProtKB=A7TAF5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g149683\|UniProtKB=A7T846	Nematostella vectensis	O