PANTHER Gene Information   
Gene Symbol(s): FGF8
Organism: Bos taurus
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Gene Name: Fibroblast growth factor
Gene ID: ENSBTAG00000001530.6
Protein ID: F1N6G8
Persistent Id: PTN000160249
Alternate Ids:
NP_001193607(refSeq) ENSBTAP00000002001(Ensembl_PRO)
331999940(GI) ENSBTAG00000001530(Ensembl)
326284(GeneID) F1N6G8_BOVIN(UniProtKB-ID)
F1N6G8(Synonym) ENSBTAT00000002001(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: FIBROBLAST GROWTH FACTOR (PTHR11486)
PANTHER Subfamily: FIBROBLAST GROWTH FACTOR 8 (PTHR11486:SF3)  
PANTHER GO-slim Molecular Function: growth factor activity
fibroblast growth factor receptor binding
PANTHER GO-slim Biological Process: regulation of cell migration
neuron differentiation
fibroblast growth factor receptor signaling pathway
positive regulation of protein phosphorylation
dorsal/ventral pattern formation
positive regulation of MAPK cascade
positive regulation of gene expression
positive regulation of cell population proliferation
animal organ morphogenesis
PANTHER GO-slim Cellular Component: extracellular space
cytoplasm
PANTHER protein class: growth factor
Pathway Categories: FGF signaling pathway
   fibroblast growth factor

GO MF Complete: growth factor activity, type 2 fibroblast growth factor receptor binding, type 1 fibroblast growth factor receptor binding
GO BP Complete: positive regulation of cell population proliferation, fibroblast growth factor receptor signaling pathway, neurogenesis, positive regulation of MAPK cascade, regulation of cell migration, dorsal/ventral pattern formation
GO CC Complete: extracellular space, cytoplasm
Reactome Pathways: FGFR3b ligand binding and activation, FGFR3c ligand binding and activation, PI3K Cascade, Intracellular signaling by second messengers, Downstream signaling of activated FGFR4, Signal Transduction, SHC-mediated cascade:FGFR4, SHC-mediated cascade:FGFR1, Downstream signaling of activated FGFR1, PI-3K cascade:FGFR4, PI-3K cascade:FGFR1, FGFR2 ligand binding and activation, FGFR1 ligand binding and activation, Negative regulation of the PI3K/AKT network, RAF/MAP kinase cascade, FGFR4 ligand binding and activation, PIP3 activates AKT signaling, Negative regulation of FGFR2 signaling, Negative regulation of FGFR1 signaling, Insulin receptor signalling cascade, Signaling by Insulin receptor, PI-3K cascade:FGFR2, FGFR3 ligand binding and activation, Downstream signaling of activated FGFR2, MAPK1/MAPK3 signaling, SHC-mediated cascade:FGFR2, Negative regulation of FGFR3 signaling, Negative regulation of FGFR4 signaling, Signaling by FGFR, FRS-mediated FGFR1 signaling, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, Phospholipase C-mediated cascade: FGFR1, Signaling by FGFR1, Signaling by FGFR2, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Phospholipase C-mediated cascade; FGFR2, FGFRL1 modulation of FGFR1 signaling, Signaling by FGFR3, Signaling by FGFR4, Phospholipase C-mediated cascade; FGFR4, Phospholipase C-mediated cascade; FGFR3, FRS-mediated FGFR2 signaling, IRS-related events triggered by IGF1R, IGF1R signaling cascade, Signaling by Receptor Tyrosine Kinases, SHC-mediated cascade:FGFR3, FRS-mediated FGFR3 signaling, MAPK family signaling cascades, Downstream signaling of activated FGFR3, IRS-mediated signalling, PI-3K cascade:FGFR3, FRS-mediated FGFR4 signaling, FGFR2c ligand binding and activation, FGFR1c ligand binding and activation