PANTHER Gene Information

Gene Symbol(s):

HAND1

Organism:

Bos taurus

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Gene Name:

Heart- and neural crest derivatives-expressed protein 1

Gene ID:

ENSBTAG00000002335

Protein ID:

Q0VCE2

Persistent Id:

PTN000598334

Alternate Ids:

111308611(GI)	BC120210(EMBL)
ENSBTAT00000003015(Ensembl_TRS)	HAND1(Synonym)
HAND1(Symbol)	ENSBTAP00000003015(Ensembl_PRO)
517952(GeneID)	NP_001069229(refSeq)
AAI20211(EMBL-CDS)	HAND1_BOVIN(UniProtKB-ID)
ENSBTAG00000002335(Ensembl)
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PANTHER Classification

PANTHER Family:	BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTOR, TWIST (PTHR23349)
PANTHER Subfamily:	HEART- AND NEURAL CREST DERIVATIVES-EXPRESSED PROTEIN 1 (PTHR23349:SF3)
PANTHER GO-slim Molecular Function:	DNA-binding transcription factor activity, RNA polymerase II-specific RNA polymerase II transcription regulatory region sequence-specific DNA binding
PANTHER GO-slim Biological Process:	heart development regulation of transcription by RNA polymerase II
PANTHER GO-slim Cellular Component:
PANTHER protein class:	basic helix-loop-helix transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	RNA polymerase II transcription regulatory region sequence-specific DNA binding, protein dimerization activity, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	heart development, trophoblast giant cell differentiation, regulation of transcription by RNA polymerase II
GO CC Complete:	nucleolus, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=4807\|UniProtKB=O96004	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000017446.3\|UniProtKB=H2QRV2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004311.3\|UniProtKB=G3QNU9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000010621.4\|UniProtKB=F7BK41	Macaca mulatta	LDO
MOUSE\|MGI=MGI=103577\|UniProtKB=Q64279	Mus musculus	LDO
RAT\|RGD=621206\|UniProtKB=P97832	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000031080.1\|UniProtKB=A0A287ACN5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000005327.3\|UniProtKB=F6QK69	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014986.5\|UniProtKB=M3WLQ6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004947.1\|UniProtKB=A0A8I3MPL4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000008678.5\|UniProtKB=F6PFU0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000005097.3\|UniProtKB=A0A6I8PEF0	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010015835\|UniProtKB=Q90691	Gallus gallus	LDO
XENLA\|Gene=hand1.L\|UniProtKB=B7ZRJ2	Xenopus laevis	O
XENLA\|Gene=hand1\|UniProtKB=O73615	Xenopus laevis	O
XENLA\|Gene=LOC108712623\|UniProtKB=A0A8J0UVK3	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-480122\|UniProtKB=A0A8J0PIQ6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015508.2\|UniProtKB=H2ML49	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000012444.1\|UniProtKB=W5N3V8	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000006582.3\|UniProtKB=F6R0Z4	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000005750.3\|UniProtKB=F6PZI7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118419791\|UniProtKB=H6T887	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC105438703\|UniProtKB=A0A7M7SWT8	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001981\|UniProtKB=Q18612	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00035748\|UniProtKB=A8XM61	Caenorhabditis briggsae	LDO
CAEBR\|WormBase=WBGene00038828\|UniProtKB=A8XW38	Caenorhabditis briggsae	LDO
CAEBR\|WormBase=WBGene00031749\|UniProtKB=A8XAJ6	Caenorhabditis briggsae	O
CAEBR\|WormBase=WBGene00029526\|UniProtKB=A8X4N4	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00203654\|UniProtKB=A0A2A6C4W9	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0032209\|UniProtKB=Q9VL05	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP004386\|UniProtKB=Q7QA78	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC004726\|UniProtKB=A0A139WNX7	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_7671\|UniProtKB=E9G5T0	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW009436\|UniProtKB=B7Q259	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG64223\|UniProtKB=T1FXR5	helobdella robusta	LDO
HELRO\|EnsemblGenome=HelroG176734\|UniProtKB=T1FAU7	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG136534\|UniProtKB=T1EIE4	helobdella robusta	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g199398\|UniProtKB=A7RMR1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g106073\|UniProtKB=A7S669	Nematostella vectensis	LDO
CRYNJ\|EnsemblGenome=CNH00430\|UniProtKB=Q5KCB3	Cryptococcus neoformans	O