PANTHER Gene Information

Gene Symbol(s):

MAD1L1

Organism:

Bos taurus

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Gene Name:

MAD1L1 protein

Gene ID:

ENSBTAG00000002474.5

Protein ID:

A7MB59

Persistent Id:

PTN000570858

Alternate Ids:

ENSBTAT00000003210(Ensembl_TRS)	156120735(GI)
A7MB59(Synonym)	NP_001095514(refSeq)
ENSBTAG00000002474(Ensembl)	BC151350(EMBL)
517837(GeneID)	A7MB59_BOVIN(UniProtKB-ID)
AAI51351(EMBL-CDS)	ENSBTAP00000003210(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 MITOTIC ARREST DEFICIENT-LIKE PROTEIN 1 (PTHR23168)
PANTHER Subfamily:	MITOTIC SPINDLE ASSEMBLY CHECKPOINT PROTEIN MAD1 (PTHR23168:SF0)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	mitotic spindle assembly checkpoint signaling attachment of mitotic spindle microtubules to kinetochore
PANTHER GO-slim Cellular Component:	mitotic spindle kinetochore nuclear envelope
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	kinetochore binding, identical protein binding
GO BP Complete:	mitotic spindle assembly checkpoint signaling, cell division, positive regulation of mitotic cell cycle spindle assembly checkpoint, regulation of metaphase plate congression, negative regulation of T cell proliferation, thymus development, attachment of mitotic spindle microtubules to kinetochore
GO CC Complete:	nuclear envelope, nuclear pore nuclear basket, mitotic spindle pole, mitotic spindle, kinetochore, MAD1 complex, mitotic spindle assembly checkpoint MAD1-MAD2 complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=6762\|UniProtKB=Q9Y6D9	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000018855.6\|UniProtKB=H2RCA9	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000034992.2\|UniProtKB=A0A2I2ZA87	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011659.4\|UniProtKB=F7HGW4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1341857\|UniProtKB=Q9WTX8	Mus musculus	LDO
RAT\|RGD=1596881\|UniProtKB=D3ZIV3	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000038766.3\|UniProtKB=A0A287A1B8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000014242.4\|UniProtKB=F6ZXL9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000005389.6\|UniProtKB=A0A5F5Y2P6	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845007094.1\|UniProtKB=A0A8I3N3B9	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017321.3\|UniProtKB=F6WVV2	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000004310.3\|UniProtKB=A0A6I8NDX6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010019848.1\|UniProtKB=A0A8V0ZC99	Gallus gallus	LDO
XENLA\|Gene=mad1l1.L\|UniProtKB=A0A8J1LRU7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6258053\|UniProtKB=Q6DEZ6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000024940.1\|UniProtKB=A0A3B3IJ39	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1081\|UniProtKB=D9IWE2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000001393.1\|UniProtKB=W5LZN2	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000005648.3\|UniProtKB=F6Y1Z7	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118429566\|UniProtKB=A0A9J7N9R4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC591426\|UniProtKB=A0A7M7NVG0	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003160\|UniProtKB=G5EFM0	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00038548\|UniProtKB=A8XVB0	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00112251\|UniProtKB=A0A2A6B9Q1	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0026326\|UniProtKB=Q7KND8	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP006632\|UniProtKB=A0A1S4GSR4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009389\|UniProtKB=D6WQX8	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_303458\|UniProtKB=E9GG79	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW015486\|UniProtKB=B7QP23	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG193983\|UniProtKB=T1FVJ3	helobdella robusta	LDO
YEAST\|SGD=S000003054\|UniProtKB=P40957	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AFL065C\|UniProtKB=Q754Z1	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000199073\|UniProtKB=Q59PD6	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E29623g\|UniProtKB=Q6C452	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00696\|UniProtKB=C8VRP6	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G13580\|UniProtKB=E9R015	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU04428\|UniProtKB=Q7RZ46	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_07595\|UniProtKB=A7EQJ3	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_02904\|UniProtKB=Q0UZB0	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC3D6.04c\|UniProtKB=P87169	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04884\|UniProtKB=B6K808	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA00730\|UniProtKB=Q5KQ23	Cryptococcus neoformans	O
CRYNJ\|EnsemblGenome=CNJ02500\|UniProtKB=Q5KA95	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_11553\|UniProtKB=A0A0D1DTE9	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_14906\|UniProtKB=E3KXK3	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_21446\|UniProtKB=F4NT61	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0287755\|UniProtKB=Q54JX0	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_152585\|UniProtKB=F0ZLR9	Dictyostelium purpureum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_260890\|UniProtKB=B8BQI5	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GCL4_PHYRM\|UniProtKB=H3GCL4	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_16g666400v5\|UniProtKB=A0A2K3CTW2	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00099p00119010\|UniProtKB=W1NRY7	Amborella trichopoda	LDO
MUSAM\|EnsemblGenome=Ma08_g08140\|UniProtKB=A0A804K476	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_000109mg\|UniProtKB=K3XDZ2	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3009G087300\|UniProtKB=C5YV75	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3003G375200\|UniProtKB=A0A1B6Q797	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb145920\|UniProtKB=B6U4F6	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os01g0877300\|UniProtKB=Q5N9G9	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_2g16210v3\|UniProtKB=I1HGB3	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0298170\|UniProtKB=A0A8I6XZ02	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS3A02G389100\|UniProtKB=A0A3B6EPD0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3B02G419700\|UniProtKB=A0A3B6FWX7	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS3D02G380600\|UniProtKB=A0A3B6H2N9	Triticum aestivum	LDO
NELNU\|Gene=LOC104593948\|UniProtKB=A0A1U7ZF77	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110803577\|UniProtKB=A0A9R0JC51	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr10g0441631\|UniProtKB=A0A251TKT1	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C500265970\|UniProtKB=A0A9R1X9K3	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a002021mg\|UniProtKB=A0A022R832	Erythranthe guttata	LDO
SOLLC\|EnsemblGenome=Solyc01g103040.3\|UniProtKB=A0A3Q7EPW0	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107818818\|UniProtKB=A0A1S4CGP7	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107824124\|UniProtKB=A0A1S4CYX9	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi12g02124\|UniProtKB=F6HK02	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_I02796\|UniProtKB=A0A059AU15	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra037948\|UniProtKB=M4FA34	Brassica campestris	LDO
ARATH\|TAIR=locus=2158804\|UniProtKB=Q9LTY1	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107900605\|UniProtKB=A0A1U8IZH6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107961827\|UniProtKB=A0A1U8PQM1	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_027116\|UniProtKB=A0A061G8K7	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g004893mg\|UniProtKB=A0A067DRE5	Citrus sinensis	LDO
POPTR\|Gene_ORFName=POPTR_004G228900\|UniProtKB=A0A3N7EV10	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_003G000900v3\|UniProtKB=A0A2K2AZF0	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_10G107000\|UniProtKB=A0A2C9V557	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_10G106700\|UniProtKB=A0A2C9V543	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0496470\|UniProtKB=B9SPB2	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_07G272700\|UniProtKB=I1KNR7	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_17G001700\|UniProtKB=A0A0R0F6B2	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g134640\|UniProtKB=A0A072UUK2	Medicago truncatula	LDO
JUGRE\|Gene=LOC118344156\|UniProtKB=A0A6P9E6R7	Juglans regia	O
JUGRE\|Gene=LOC108988937\|UniProtKB=A0A6P9DZE4	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_5G630750\|UniProtKB=A0A0A0KV95	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G585300\|UniProtKB=M5Y3N8	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_402372\|UniProtKB=D8QQF2	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_439954\|UniProtKB=D8R8H7	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c17_20400\|UniProtKB=A0A7I4BF90	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0034s0031\|UniProtKB=A0A2R6X5Q2	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000970060\|UniProtKB=A0A0U9HJ93	Klebsormidium nitens	LDO