PANTHER Gene Information

Gene Symbol(s):

S1PR1

Organism:

Bos taurus

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Gene Name:

Sphingosine 1-phosphate receptor 1

Gene ID:

ENSBTAG00000005990

Protein ID:

Q5E9P3

Persistent Id:

PTN007706083

Alternate Ids:

BT020877(EMBL)	NP_001013603(refSeq)
75070049(GI)	ENSBTAT00000007861(Ensembl_TRS)
S1PR1(Symbol)	281135(GeneID)
S1PR1_BOVIN(UniProtKB-ID)	S1P receptor 1(Synonym)
AAI14046(EMBL-CDS)	ENSBTAG00000005990(Ensembl)
ENSBTAP00000007861(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	G-PROTEIN COUPLED RECEPTOR (PTHR22750)
PANTHER Subfamily:	SPHINGOSINE 1-PHOSPHATE RECEPTOR 1 (PTHR22750:SF16)
PANTHER GO-slim Molecular Function:	bioactive lipid receptor activity
PANTHER GO-slim Biological Process:	angiogenesis adenylate cyclase-activating G protein-coupled receptor signaling pathway regulation of metabolic process
PANTHER GO-slim Cellular Component:	cytoplasm plasma membrane
PANTHER protein class:	G-protein coupled receptor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	G protein-coupled receptor binding, sphingosine-1-phosphate receptor activity
GO BP Complete:	adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway, cell population proliferation, heart trabecula morphogenesis, positive regulation of cell population proliferation, regulation of bone resorption, adenylate cyclase-activating G protein-coupled receptor signaling pathway, brain development, sphingosine-1-phosphate receptor signaling pathway, cardiac muscle tissue growth involved in heart morphogenesis, chemotaxis, angiogenesis, blood vessel maturation, regulation of metabolic process, lamellipodium assembly, T cell migration, regulation of cell adhesion, leukocyte chemotaxis, cell migration, actin cytoskeleton organization, regulation of bone mineralization
GO CC Complete:	presynapse, endosome, cytoplasm, membrane raft, external side of plasma membrane, plasma membrane, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Class A/1 (Rhodopsin-like receptors), Signaling by GPCR, Lysosphingolipid and LPA receptors, GPCR ligand binding, Signal Transduction

Orthologs

ID	Organism	Type
HUMAN\|HGNC=3165\|UniProtKB=P21453	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001014.5\|UniProtKB=H2RIN7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000028363.2\|UniProtKB=G3SKC0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000042059.2\|UniProtKB=H9EUW9	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1096355\|UniProtKB=O08530	Mus musculus	LDO
RAT\|RGD=61958\|UniProtKB=P48303	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000029849.4\|UniProtKB=I3LIS0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011626.3\|UniProtKB=F7BGR2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000006919.5\|UniProtKB=M3W6R4	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845012064.1\|UniProtKB=A0A8I3NL43	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000023248.2\|UniProtKB=F6XRS8	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000012701.2\|UniProtKB=F6ZG05	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010023590.1\|UniProtKB=R4GHZ8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000044516.1\|UniProtKB=A0A803T1B4	Anolis carolinensis	LDO
XENLA\|Gene=s1pr1.S\|UniProtKB=A0A1L8GGH0	Xenopus laevis	O
XENLA\|Gene=s1pr1.L\|UniProtKB=Q6GLU6	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-956190\|UniProtKB=F6Y7C0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000014096.2\|UniProtKB=H2MGD8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-001228-2\|UniProtKB=Q9DDK4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000017643.1\|UniProtKB=W5NM89	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000007801.3\|UniProtKB=F6X383	Ciona intestinalis	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_225039\|UniProtKB=C3YXD0	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_91694\|UniProtKB=C3YA26	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_94121\|UniProtKB=C3ZUF0	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_103731\|UniProtKB=C3Z933	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_99285\|UniProtKB=C3Z8X4	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_109728\|UniProtKB=C3ZLW4	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_78446\|UniProtKB=C3Z456	Branchiostoma floridae	O
BRAFL\|Gene=LOC118408465\|UniProtKB=A0A9J7HTA6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118430679\|UniProtKB=A0A9J7NCA0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118430512\|UniProtKB=A0A9J7MA07	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431303\|UniProtKB=A0A9J7ME22	Branchiostoma floridae	O
BRAFL\|Gene=LOC118411711\|UniProtKB=A0A9J7MK08	Branchiostoma floridae	O
BRAFL\|Gene=LOC118423182\|UniProtKB=A0A9J7LRU7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422239\|UniProtKB=A0A9J7LPK3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118411513\|UniProtKB=A0A9J7KSL9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118425970\|UniProtKB=A0A9J7LYE4	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422693\|UniProtKB=A0A9J7N180	Branchiostoma floridae	O
BRAFL\|Gene=LOC118419207\|UniProtKB=A0A9J7LEM9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118416252\|UniProtKB=A0A9J7L768	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418893\|UniProtKB=A0A9J7LDQ9	Branchiostoma floridae	O
BRAFL\|Gene=LOC118417651\|UniProtKB=A0A9J7LBI8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409195\|UniProtKB=A0A9J7HXR8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418014\|UniProtKB=A0A9J7LCK0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421205\|UniProtKB=A0A9J7MZ75	Branchiostoma floridae	O
BRAFL\|Gene=LOC118412300\|UniProtKB=A0A9J7MKW8	Branchiostoma floridae	O
BRAFL\|Gene=LOC118411668\|UniProtKB=A0A9J7MK42	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421240\|UniProtKB=A0A9J7LK33	Branchiostoma floridae	O
BRAFL\|Gene=LOC118414018\|UniProtKB=A0A9J7L013	Branchiostoma floridae	O
BRAFL\|Gene=LOC118410515\|UniProtKB=A0A9J7MI50	Branchiostoma floridae	O
BRAFL\|Gene=LOC118418192\|UniProtKB=A0A9J7MV09	Branchiostoma floridae	O
BRAFL\|Gene=LOC118432829\|UniProtKB=A0A9J7MFL1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118409078\|UniProtKB=A0A9J7HUK5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118412299\|UniProtKB=A0A9J7KVB3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118425314\|UniProtKB=A0A9J7N4S5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118411671\|UniProtKB=A0A9J7KT60	Branchiostoma floridae	O
BRAFL\|Gene=LOC118424938\|UniProtKB=A0A9J7LV18	Branchiostoma floridae	O
BRAFL\|Gene=LOC118411672\|UniProtKB=A0A9J7KUE5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118430050\|UniProtKB=A0A9J7NBB6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118431527\|UniProtKB=A0A9J7NCX7	Branchiostoma floridae	O
BRAFL\|Gene=LOC118422249\|UniProtKB=A0A9J7LR13	Branchiostoma floridae	O
BRAFL\|Gene=LOC118411673\|UniProtKB=A0A9J7KT34	Branchiostoma floridae	O
BRAFL\|Gene=LOC118419208\|UniProtKB=A0A9J7LFH5	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407102\|UniProtKB=A0A9J7KK55	Branchiostoma floridae	O
BRAFL\|Gene=LOC118411669\|UniProtKB=A0A9J7MJZ3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118413367\|UniProtKB=A0A9J7KY28	Branchiostoma floridae	O
BRAFL\|Gene=LOC118424635\|UniProtKB=A0A9J7LVF1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118424406\|UniProtKB=A0A9J7LUT1	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC100892341\|UniProtKB=A0A7M7GFM8	Strongylocentrotus purpuratus	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_340718\|UniProtKB=E9I4M7	Daphnia pulex	O