PANTHER Gene Information

Gene Symbol(s):

LARS2

Organism:

Bos taurus

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Gene Name:

leucine--tRNA ligase

Gene ID:

ENSBTAG00000007315.6

Protein ID:

E1B768

Persistent Id:

PTN000236440

Alternate Ids:

ENSBTAG00000007315(Ensembl)	E1B768_BOVIN(UniProtKB-ID)
E1B768(Synonym)	ENSBTAP00000052354(Ensembl_PRO)
ENSBTAT00000054819(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	LEUCYL-TRNA SYNTHETASE (PTHR43740)
PANTHER Subfamily:	LEUCINE--TRNA LIGASE, MITOCHONDRIAL (PTHR43740:SF2)
PANTHER GO-slim Molecular Function:	catalytic activity, acting on RNA ligase activity
PANTHER GO-slim Biological Process:	amino acid metabolic process translation tRNA metabolic process
PANTHER GO-slim Cellular Component:
PANTHER protein class:	aminoacyl-tRNA synthetase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP binding, leucine-tRNA ligase activity, aminoacyl-tRNA editing activity
GO BP Complete:	leucyl-tRNA aminoacylation, aminoacyl-tRNA metabolism involved in translational fidelity, mitochondrial translation
GO CC Complete:	mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=17095\|UniProtKB=Q15031	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014833.4\|UniProtKB=H2QMF8	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015767.3\|UniProtKB=G3RI94	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000018020.4\|UniProtKB=A0A1D5QAT7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2142973\|UniProtKB=Q8VDC0	Mus musculus	LDO
RAT\|RGD=1308429\|UniProtKB=A0A8I5ZU78	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000011312.5\|UniProtKB=A0A5G2R8T0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000024346.4\|UniProtKB=F6Z1A6	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000009610.6\|UniProtKB=A0A5F5XX76	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845012761.1\|UniProtKB=A0A8I3RX83	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000011311.4\|UniProtKB=F6WJ64	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000006800.4\|UniProtKB=F6WC89	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010017552.1\|UniProtKB=A0A8V0YV38	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000014604.4\|UniProtKB=H9GLE6	Anolis carolinensis	LDO
XENLA\|Gene=lars2.L\|UniProtKB=A0A1L8FWM4	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-956205\|UniProtKB=F7A3Z3	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000004574.2\|UniProtKB=H2LIC8	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-070928-3\|UniProtKB=A7MBM0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002048.1\|UniProtKB=W5M1Y4	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000003591.3\|UniProtKB=F6XK10	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118413234\|UniProtKB=A0A9J7KXI3	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC587005\|UniProtKB=A0A7M7N4J6	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00003074\|UniProtKB=Q23511	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG11879\|UniProtKB=A8XE78	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00112413\|UniProtKB=A0A8R1YEU0	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00304902\|UniProtKB=A0A8R1V340	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0027085\|UniProtKB=Q9VZ82	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP002014\|UniProtKB=A0A1S4GDM0	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003172\|UniProtKB=D6WEL0	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW023069\|UniProtKB=B7QLY2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG112157\|UniProtKB=T1EFH3	helobdella robusta	LDO
YEAST\|SGD=S000004374\|UniProtKB=P11325	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AER043C\|UniProtKB=Q757H0	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000195709\|UniProtKB=A0A1D8PQ56	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F02299g\|UniProtKB=Q6C363	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_06526\|UniProtKB=Q5AYV4	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_6G04910\|UniProtKB=Q4WDI9	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03814\|UniProtKB=P15181	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_00696\|UniProtKB=A7E5X1	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_01135\|UniProtKB=Q0V4C9	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC4G8.09\|UniProtKB=Q09828	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_04738\|UniProtKB=B6K7M2	Schizosaccharomyces japonicus	LDO
DICDI\|dictyBase=DDB_G0291346\|UniProtKB=Q54ET5	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_94325\|UniProtKB=F0ZI59	Dictyostelium purpureum	LDO
PLAF7\|EnsemblGenome=PF3D7_0828200\|UniProtKB=Q8IBB3	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_261684\|UniProtKB=B8BX36	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3H4A7_PHYRM\|UniProtKB=H3H4A7	Phytophthora ramorum	LDO
HALSA\|EnsemblGenome=VNG_2223G\|UniProtKB=Q9HN72	Halobacterium salinarum	LDO
CHLAA\|EnsemblGenome=Caur_2759\|UniProtKB=A9WK84	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO2571\|UniProtKB=Q9RDL5	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv0041\|UniProtKB=P9WFV1	Mycobacterium tuberculosis	LDO
MYCGE\|EnsemblGenome=MG_266\|UniProtKB=P47508	mycoplasma genitalium	LDO
CLOBH\|Gene_OrderedLocusName=CBO0186\|UniProtKB=A5HY79	Clostridium botulinum	LDO
STRR6\|EnsemblGenome=spr0235\|UniProtKB=Q8DRB6	Streptococcus pneumoniae	LDO
STAA8\|EnsemblGenome=SAOUHSC_01875\|UniProtKB=Q2FXH2	Staphylococcus aureus	LDO
LISMO\|EnsemblGenome=CAC99738\|UniProtKB=Q8Y6M4	Listeria monocytogenes	LDO
BACSU\|EnsemblGenome=BSU_30320\|UniProtKB=P36430	Bacillus subtilis	LDO
BACCR\|EnsemblGenome=BC_4737\|UniProtKB=Q816T0	Bacillus cereus	LDO
THEMA\|EnsemblGenome=TM_0168\|UniProtKB=Q9WY15	Thermotoga maritima	LDO
DEIRA\|EnsemblGenome=DR_2174\|UniProtKB=Q9RSF0	Deinococcus radiodurans	LDO
GLOVI\|EnsemblGenome=BAC92022\|UniProtKB=Q7NE01	Gloeobacter violaceus	LDO
SYNY3\|EnsemblGenome=BAA17302\|UniProtKB=P73274	Synechocystis	LDO
LEPIN\|EnsemblGenome=LA_3714\|UniProtKB=Q8EZY7	Leptospira interrogans	LDO
BACTN\|EnsemblGenome=BT_3126\|UniProtKB=Q8A329	Bacteroides thetaiotaomicron	LDO
CHLTR\|EnsemblGenome=CT_209\|UniProtKB=O84211	Chlamydia trachomatis	LDO
RHOBA\|EnsemblGenome=RB8919\|UniProtKB=Q7UMC0	Rhodopirellula baltica	LDO
AQUAE\|EnsemblGenome=aq_351\|UniProtKB=O66680	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A1204\|UniProtKB=B5YLA8	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_1563\|UniProtKB=B8E2J3	Dictyoglomus turgidum	LDO
FUSNN\|EnsemblGenome=FN1517\|UniProtKB=Q8RIQ3	Fusobacterium nucleatum	LDO
HELPY\|EnsemblGenome=HP_1547\|UniProtKB=P56457	Helicobacter pylori	LDO
NEIMB\|EnsemblGenome=NMB1897\|UniProtKB=Q9JXT2	Neisseria meningitidis serogroup b	LDO
GEOSL\|EnsemblGenome=GSU2209\|UniProtKB=Q74AZ0	Geobacter sulfurreducens	LDO
BRADU\|EnsemblGenome=BAC45892\|UniProtKB=Q89WQ1	Bradyrhizobium diazoefficiens	LDO
COXBU\|EnsemblGenome=CBU_0559\|UniProtKB=Q83DY1	Coxiella burnetii	LDO
HAEIN\|EnsemblGenome=HI_0921\|UniProtKB=P43827	Haemophilus influenzae	LDO
SHEON\|Gene_OrderedLocusName=SO_1174\|UniProtKB=Q8EHP4	Shewanella oneidensis	LDO
VIBCH\|EnsemblGenome=VC_0956\|UniProtKB=Q9KTE6	Vibrio cholerae	LDO
XANCP\|EnsemblGenome=XCC2620\|UniProtKB=Q8P7J1	Xanthomonas campestris	LDO
PSEAE\|EnsemblGenome=PA3987\|UniProtKB=Q9HX33	Pseudomonas aeruginosa	LDO
SALTY\|EnsemblGenome=STM0648\|UniProtKB=Q8ZQZ6	Salmonella typhimurium	LDO
YERPE\|EnsemblGenome=YP_1103\|UniProtKB=Q8ZDF8	Yersinia pestis	LDO
ECOLI\|EnsemblGenome=BAA35289\|UniProtKB=P07813	Escherichia coli	LDO