PANTHER Gene Information

Gene Symbol(s):

TMLHE

Organism:

Bos taurus

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Gene Name:

Trimethyllysine dioxygenase, mitochondrial

Gene ID:

ENSBTAG00000011648

Protein ID:

Q0VC74

Persistent Id:

PTN001642740

Alternate Ids:

118574154(GI)	TMLHE(Symbol)
ENSBTAT00000015469(Ensembl_TRS)	AAI20319(EMBL-CDS)
BC120318(EMBL)	TML dioxygenase(Synonym)
ENSBTAP00000015469(Ensembl_PRO)	ENSBTAG00000011648(Ensembl)
1.14.11.8 {ECO:0000250\|UniProtKB:Q9NVH6}(EC)	535630(GeneID)
TMLH_BOVIN(UniProtKB-ID)	NM_001076064(refSeq)
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PANTHER Classification

PANTHER Family:	GAMMA-BUTYROBETAINE HYDROXYLASE-RELATED (PTHR10696)
PANTHER Subfamily:	TRIMETHYLLYSINE DIOXYGENASE, MITOCHONDRIAL (PTHR10696:SF51)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	organonitrogen compound biosynthetic process cellular modified amino acid metabolic process cellular nitrogen compound biosynthetic process
PANTHER GO-slim Cellular Component:	mitochondrion
PANTHER protein class:	hydroxylase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	trimethyllysine dioxygenase activity, iron ion binding
GO BP Complete:	carnitine biosynthetic process
GO CC Complete:	mitochondrial matrix, mitochondrion

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Carnitine synthesis, Metabolism of amino acids and derivatives, Metabolism

Orthologs

ID	Organism	Type
HUMAN\|HGNC=18308\|UniProtKB=Q9NVH6	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000022464.6\|UniProtKB=A0A2I3S0N4	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000045691.1\|UniProtKB=K7DHL4	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000024008.2\|UniProtKB=G3S446	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000009481.4\|UniProtKB=G7NSZ0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2180203\|UniProtKB=Q91ZE0	Mus musculus	LDO
RAT\|RGD=620629\|UniProtKB=Q91ZW6	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00005007181.1\|UniProtKB=F1RZS1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000012334.4\|UniProtKB=A0A9L0SQK4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000023758.4\|UniProtKB=A0A337SI26	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845018126.1\|UniProtKB=A0A8I3P563	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006132.2\|UniProtKB=F7E1P0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000008712.4\|UniProtKB=F6RNL6	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010015194\|UniProtKB=Q5F4B3	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000015669.4\|UniProtKB=H9GML0	Anolis carolinensis	LDO
XENLA\|Gene=tmlhe.S\|UniProtKB=Q6P426	Xenopus laevis	O
XENLA\|Gene=tmlhe.L\|UniProtKB=A0A1L8F7T7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-978203\|UniProtKB=A4IHQ2	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000010326.2\|UniProtKB=H2M3D7	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-091204-144\|UniProtKB=E7F0M9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000013710.1\|UniProtKB=W5N8E5	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118427387\|UniProtKB=A0A9J7M2C2	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC584681\|UniProtKB=A0A7M7NK65	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00001523\|UniProtKB=Q21526	Caenorhabditis elegans	LDO
CAEBR\|Gene_ORFName=CBG00615\|UniProtKB=A8WNG3	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00117958\|UniProtKB=A0A2A6CP61	Pristionchus pacificus	O
PRIPA\|EnsemblGenome=WBGene00113449\|UniProtKB=A0A2A6CZM7	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0038795\|UniProtKB=Q9VDM7	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP029598\|UniProtKB=A0A453Z026	Anopheles gambiae	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_306710\|UniProtKB=E9GXY5	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG161402\|UniProtKB=T1ERG0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g237606\|UniProtKB=A7SYU0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g208460\|UniProtKB=A7S8L4	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g208458\|UniProtKB=A7S8L2	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g122521\|UniProtKB=A7SLB9	Nematostella vectensis	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_23751\|UniProtKB=A9UUQ7	Monosiga brevicollis	LDO
EREGS\|EnsemblGenome=AGOS_AEL035W\|UniProtKB=Q757P7	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000194928\|UniProtKB=A0A1D8PNJ2	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_C10604g\|UniProtKB=Q6CCC7	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_10527\|UniProtKB=C8V493	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_1G06180\|UniProtKB=Q4WJF3	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU03802\|UniProtKB=Q96UB1	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_07291\|UniProtKB=A7EPP2	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_08253\|UniProtKB=Q0UJ11	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CNF02980\|UniProtKB=Q5KF50	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_11458\|UniProtKB=A0A0D1C7M5	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_19005\|UniProtKB=E3L8W7	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_10446\|UniProtKB=F4P0U4	Batrachochytrium dendrobatidis	LDO
THAPS\|EnsemblGenome=THAPS_6667\|UniProtKB=B5YP61	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3GGD2_PHYRM\|UniProtKB=H3GGD2	Phytophthora ramorum	LDO
STRCO\|Gene_OrderedLocusName=SCO3236\|UniProtKB=Q9Z4Z5	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO2693\|UniProtKB=Q9KYH9	Streptomyces coelicolor	O
GLOVI\|Gene=Q7NJD5_GLOVI\|UniProtKB=Q7NJD5	Gloeobacter violaceus	O
LEPIN\|EnsemblGenome=LA_3126\|UniProtKB=Q8F1K7	Leptospira interrogans	O
VIBCH\|EnsemblGenome=VC_1944\|UniProtKB=Q9KQQ4	Vibrio cholerae	O
PSEAE\|EnsemblGenome=PA2255\|UniProtKB=Q9I1L4	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA2303\|UniProtKB=Q9I1H2	Pseudomonas aeruginosa	O
PSEAE\|EnsemblGenome=PA2304\|UniProtKB=Q9I1H1	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM2789\|UniProtKB=P0CL02	Salmonella typhimurium	O