PANTHER Gene Information

Gene Symbol(s):

PIGL

Organism:

Bos taurus

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Tree

Gene Name:

N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase

Gene ID:

ENSBTAG00000013273

Protein ID:

A6QQ24

Persistent Id:

PTN000313027

Alternate Ids:

3.5.1.89(EC)	NP_001093781(refSeq)
Phosphatidylinositol-glycan biosynthesis class L protein(Synonym)	154152017(GI)
ENSBTAP00000017653(Ensembl_PRO)	507080(GeneID)
ENSBTAG00000013273(Ensembl)	PIGL_BOVIN(UniProtKB-ID)
BC149604(EMBL)	AAI49605(EMBL-CDS)
PIGL(Symbol)	ENSBTAT00000017653(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED (PTHR12993)
PANTHER Subfamily:	N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE (PTHR12993:SF11)
PANTHER GO-slim Molecular Function:	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	deacetylase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	N-acetylglucosaminylphosphatidylinositol deacetylase activity
GO BP Complete:	GPI anchor biosynthetic process
GO CC Complete:	endoplasmic reticulum membrane, endoplasmic reticulum

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Synthesis of glycosylphosphatidylinositol (GPI), Post-translational protein modification, Metabolism of proteins, Post-translational modification: synthesis of GPI-anchored proteins

Orthologs

ID	Organism	Type
HUMAN\|HGNC=8966\|UniProtKB=Q9Y2B2	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000008809.6\|UniProtKB=A0A2I3SPY0	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000002753.3\|UniProtKB=G3QJW0	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000030296.3\|UniProtKB=F6W3N4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2681271\|UniProtKB=Q5SX19	Mus musculus	LDO
RAT\|RGD=620437\|UniProtKB=O35790	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000035103.3\|UniProtKB=A0A5G2QIF0	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000006052.4\|UniProtKB=A0A5F5PJJ4	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000010824.5\|UniProtKB=M3WE00	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845004422.1\|UniProtKB=A0A8I3MTN3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000011208.4\|UniProtKB=F6SQC6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000012686.3\|UniProtKB=F7B038	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010029732.1\|UniProtKB=A0A8V1ALZ0	Gallus gallus	LDO
XENLA\|Gene=pigl.L\|UniProtKB=A0A1L8HD05	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-963122\|UniProtKB=A0A6I8QB74	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000029758.1\|UniProtKB=A0A3B3I3G9	Oryzias latipes	LDO
DANRE\|Gene=pigl\|UniProtKB=A0A8M1P3K2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000003499.1\|UniProtKB=W5M6Y2	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004551.3\|UniProtKB=F6ZQH5	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118425647\|UniProtKB=A0A9J7LWR6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC100893824\|UniProtKB=A0A7M7GHG1	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00013131\|UniProtKB=D4YWC2	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00029840\|UniProtKB=A8X5G2	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0038763\|UniProtKB=A0A0B4K6Q5	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP001955\|UniProtKB=Q7PYI6	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015071\|UniProtKB=D2A621	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_306215\|UniProtKB=E9GW24	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW019246\|UniProtKB=B7PW20	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG116956\|UniProtKB=T1EGI8	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g157870\|UniProtKB=A7RFB9	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG57271\|UniProtKB=B3RYZ5	Trichoplax adhaerens	LDO
YEAST\|SGD=S000004894\|UniProtKB=P23797	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ABL120W\|UniProtKB=Q75DZ3	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000183720\|UniProtKB=A0A1D8PEU2	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E21934g\|UniProtKB=Q6C513	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_08908\|UniProtKB=Q5AS22	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_8G00630\|UniProtKB=Q4WB08	Neosartorya fumigata	O
EMENI\|EnsemblGenome=ANIA_00049\|UniProtKB=C8VR31	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_8G02060\|UniProtKB=Q4WBF0	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_5G12550\|UniProtKB=Q4WVL6	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU09510\|UniProtKB=Q7S1Q5	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_11606\|UniProtKB=A7F1Y5	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_09981\|UniProtKB=Q0UE33	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAPB2B4.01c\|UniProtKB=Q9HDW9	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01416\|UniProtKB=B6JXV3	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNC00580\|UniProtKB=Q5KL67	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_00302\|UniProtKB=A0A0D1E7L5	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_11495\|UniProtKB=E3KLX7	Puccinia graminis	O
PUCGT\|EnsemblGenome=PGTG_21798\|UniProtKB=H6QSI5	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_12159\|UniProtKB=E3KPG8	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_85693\|UniProtKB=F4NS65	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_015270\|UniProtKB=C4M0W5	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0293136\|UniProtKB=Q54C64	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_92416\|UniProtKB=F0ZRJ5	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_09_0040\|UniProtKB=Q8I8A4	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.3900\|UniProtKB=Q382X3	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_14236\|UniProtKB=D3KH21	Giardia intestinalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0624700\|UniProtKB=C6KT83	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00009494001\|UniProtKB=A0CQS9	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00019956001\|UniProtKB=A0DT96	Paramecium tetraurelia	O
PHYRM\|Gene=H3G7D9_PHYRM\|UniProtKB=H3G7D9	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_06g300100v5\|UniProtKB=A0A2K3DQW6	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00001p00033800\|UniProtKB=W1NLM6	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_228G00050\|UniProtKB=A0A0K9PIH8	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma10_g07940\|UniProtKB=A0A804KTU3	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_022992mg\|UniProtKB=K3Z8X2	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3006G120700\|UniProtKB=C5YAR1	Sorghum bicolor	O
SORBI\|EnsemblGenome=SORBI_3006G268300\|UniProtKB=A0A1B6PP60	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb066050\|UniProtKB=A0A804M861	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb433850\|UniProtKB=C0HHS8	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os04g0678800\|UniProtKB=Q7XKF2	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_5g26260v3\|UniProtKB=I1J3D9	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0209450\|UniProtKB=M0XJH3	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS2A02G590300\|UniProtKB=A0A3B6BAH8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G602600\|UniProtKB=A0A3B6CGU3	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G593400\|UniProtKB=A0A3B6CGM8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G584100\|UniProtKB=A0A3B6BAC0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G564000\|UniProtKB=A0A3B6DP05	Triticum aestivum	LDO
NELNU\|Gene=LOC104610190\|UniProtKB=A0A1U8BF11	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110801269\|UniProtKB=A0A9R0J9D0	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr15g0694221\|UniProtKB=A0A9K3H245	Helianthus annuus	LDO
HELAN\|Gene_ORFName=HannXRQ_Chr15g0480201\|UniProtKB=A0A251SA86	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C700355650\|UniProtKB=A0A9R1V3F9	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a012207mg\|UniProtKB=A0A022Q3L1	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_12283\|UniProtKB=A0A2G2ZPC4	Capsicum annuum	O
CAPAN\|EnsemblGenome=T459_05464\|UniProtKB=A0A1U8FP62	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG403029595\|UniProtKB=M1CW73	Solanum tuberosum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400009224\|UniProtKB=M1AJ20	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc11g017400.2\|UniProtKB=A0A3Q7IU50	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107812760\|UniProtKB=A0A1S4BXB0	Nicotiana tabacum	O
TOBAC\|Gene=LOC107785969\|UniProtKB=A0A1S3ZEW0	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi07g00857\|UniProtKB=D7U3H4	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_B03172\|UniProtKB=A0A059D7S3	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra007381\|UniProtKB=M4CT39	Brassica campestris	O
BRACM\|EnsemblGenome=Bra003321\|UniProtKB=M4CGI8	Brassica campestris	LDO
ARATH\|TAIR=locus=2038608\|UniProtKB=Q6NLZ3	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2085440\|UniProtKB=Q6DBN0	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107959467\|UniProtKB=A0A1U8PLE6	Gossypium hirsutum	O
GOSHI\|Gene=LOC107959595\|UniProtKB=A0A1U8PIZ7	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_001392\|UniProtKB=A0A061DK83	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g025126mg\|UniProtKB=A0A067H2E5	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_012G041700v3\|UniProtKB=B9I4U6	Populus trichocarpa	LDO
RICCO\|Gene_ORFName=RCOM_1185650\|UniProtKB=B9SN63	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_05G126500\|UniProtKB=I1K2Y4	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G081300\|UniProtKB=I1KRC3	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_4g094538\|UniProtKB=A0A072UPQ8	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr15_11290\|UniProtKB=A0A2I4EW30	Juglans regia	O
JUGRE\|EnsemblGenome=Jr15_11300\|UniProtKB=A0A2I4EW37	Juglans regia	O
JUGRE\|EnsemblGenome=Jr06_16660\|UniProtKB=A0A2I4GZ08	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_1G012160\|UniProtKB=A0A0A0LP92	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_5G069900\|UniProtKB=A0A251P6D9	Prunus persica	LDO
PHYPA\|EnsemblGenome=Pp3c13_19470\|UniProtKB=A0A2K1JMI2	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0029s0047\|UniProtKB=A0A2R6X8V1	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_007060080\|UniProtKB=A0A1Y1IP53	Klebsormidium nitens	LDO
SACS2\|EnsemblGenome=SSO2901\|UniProtKB=Q97UU2	Sulfolobus solfataricus	LDO
METAC\|EnsemblGenome=MA_2464\|UniProtKB=Q8TN29	Methanosarcina acetivorans	LDO
THEKO\|EnsemblGenome=TK1764\|UniProtKB=Q6F4N1	Thermococcus kodakaraensis	LDO
CHLAA\|EnsemblGenome=Caur_1112\|UniProtKB=A9WJ66	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_2341\|UniProtKB=A9WGL8	Chloroflexus aurantiacus	O
STRR6\|EnsemblGenome=spr0138\|UniProtKB=Q8CZ99	Streptococcus pneumoniae	O
DEIRA\|EnsemblGenome=DR_A0063\|UniProtKB=Q9RZ91	Deinococcus radiodurans	O
DEIRA\|EnsemblGenome=DR_A0132\|UniProtKB=Q9RZ21	Deinococcus radiodurans	O
GLOVI\|Gene=Q7NCD0_GLOVI\|UniProtKB=Q7NCD0	Gloeobacter violaceus	O
BRADU\|Gene=Q89NJ7_BRADU\|UniProtKB=Q89NJ7	Bradyrhizobium diazoefficiens	O
XANCP\|EnsemblGenome=XCC1645\|UniProtKB=Q8PA48	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA5002\|UniProtKB=Q9HUG3	Pseudomonas aeruginosa	O
YERPE\|Gene_OrderedLocusName=YPO0083\|UniProtKB=Q0WKL1	Yersinia pestis	O
CHLAA\|EnsemblGenome=Caur_2615\|UniProtKB=A9WIU4	Chloroflexus aurantiacus	O
CHLAA\|EnsemblGenome=Caur_0355\|UniProtKB=A9WDK0	Chloroflexus aurantiacus	O
STRCO\|Gene_OrderedLocusName=SCO7116\|UniProtKB=Q9FC70	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO0804\|UniProtKB=Q9RD73	Streptomyces coelicolor	O
CHLAA\|EnsemblGenome=Caur_2243\|UniProtKB=A9WFV2	Chloroflexus aurantiacus	LDO
STRCO\|Gene_OrderedLocusName=SCO7632\|UniProtKB=Q9F3Q5	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO6025\|UniProtKB=O69855	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCP1.306\|UniProtKB=Q99PY5	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO6377\|UniProtKB=O86669	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO5126\|UniProtKB=Q9F344	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv1170\|UniProtKB=P9WJN3	Mycobacterium tuberculosis	O
STRCO\|Gene_OrderedLocusName=SCO4967\|UniProtKB=Q9ADK0	Streptomyces coelicolor	LDO
MYCTU\|Gene_OrderedLocusName=Rv0323c\|UniProtKB=L0T643	Mycobacterium tuberculosis	O
MYCTU\|Gene_OrderedLocusName=Rv1082\|UniProtKB=P9WJN1	Mycobacterium tuberculosis	LDO
DEIRA\|EnsemblGenome=DR_0081\|UniProtKB=Q9RY69	Deinococcus radiodurans	O
DEIRA\|EnsemblGenome=DR_1203\|UniProtKB=Q9RV27	Deinococcus radiodurans	O
DEIRA\|EnsemblGenome=DR_0450\|UniProtKB=Q9RX65	Deinococcus radiodurans	LDO
RHOBA\|EnsemblGenome=RB3342\|UniProtKB=Q7UUE5	Rhodopirellula baltica	LDO
STRCO\|Gene_OrderedLocusName=SCO0394\|UniProtKB=Q9RJJ4	Streptomyces coelicolor	O
STRR6\|EnsemblGenome=spr0962\|UniProtKB=Q8DPX3	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_00550\|UniProtKB=Q2G0L0	Staphylococcus aureus	O
BACSU\|EnsemblGenome=BSU_19460\|UniProtKB=O31857	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_3461\|UniProtKB=Q81AU5	Bacillus cereus	O
BACSU\|EnsemblGenome=BSU_22470\|UniProtKB=P42981	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_1534\|UniProtKB=Q81FP2	Bacillus cereus	O
GLOVI\|Gene=Q7NIJ9_GLOVI\|UniProtKB=Q7NIJ9	Gloeobacter violaceus	O
RHOBA\|EnsemblGenome=RB12891\|UniProtKB=Q7UHX5	Rhodopirellula baltica	O
RHOBA\|EnsemblGenome=RB10036\|UniProtKB=Q7UKN9	Rhodopirellula baltica	O
RHOBA\|EnsemblGenome=RB5540\|UniProtKB=Q7URP5	Rhodopirellula baltica	O
ECOLI\|EnsemblGenome=BAE76145\|UniProtKB=P71311	Escherichia coli	O