PANTHER Gene Information

Gene Symbol(s):

SLC6A13

Organism:

Bos taurus

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Gene Name:

Sodium- and chloride-dependent GABA transporter 2

Gene ID:

ENSBTAG00000014525

Protein ID:

A5PJX7

Persistent Id:

PTN000177941

Alternate Ids:

523784(GeneID)	ENSBTAP00000019308(Ensembl_PRO)
149643039(GI)	NP_001092497(refSeq)
BC142276(EMBL)	ENSBTAG00000014525(Ensembl)
SLC6A13(Symbol)	ENSBTAT00000019308(Ensembl_TRS)
AAI42277(EMBL-CDS)	S6A13(Synonym)
S6A13_BOVIN(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	SODIUM/CHLORIDE DEPENDENT TRANSPORTER (PTHR11616)
PANTHER Subfamily:	SODIUM- AND CHLORIDE-DEPENDENT GABA TRANSPORTER 2 (PTHR11616:SF111)
PANTHER GO-slim Molecular Function:	chloride transmembrane transporter activity amino acid:sodium symporter activity secondary active monocarboxylate transmembrane transporter activity
PANTHER GO-slim Biological Process:	amino acid transport sodium ion transmembrane transport
PANTHER GO-slim Cellular Component:	cell projection plasma membrane
PANTHER protein class:	primary active transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	gamma-aminobutyric acid:sodium:chloride symporter activity
GO BP Complete:	neurotransmitter transport, monocarboxylic acid transport, sodium ion transmembrane transport, gamma-aminobutyric acid transport, amino acid transport, amino acid import across plasma membrane
GO CC Complete:	basolateral plasma membrane, cell projection, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Reuptake of GABA, Neurotransmitter release cycle, Na+/Cl- dependent neurotransmitter transporters, Transmission across Chemical Synapses, Neuronal System, SLC-mediated transmembrane transport, Transport of small molecules, GABA synthesis, release, reuptake and degradation, Transport of bile salts and organic acids, metal ions and amine compounds

Orthologs

ID	Organism	Type
HUMAN\|HGNC=11046\|UniProtKB=Q9NSD5	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000004506.6\|UniProtKB=H2Q562	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004892.3\|UniProtKB=G3QQD1	Gorilla gorilla gorilla	LDO
MOUSE\|MGI=MGI=95629\|UniProtKB=P31649	Mus musculus	LDO
RAT\|RGD=620788\|UniProtKB=P31646	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000030076.4\|UniProtKB=I3LR93	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000051467.1\|UniProtKB=F7DSR2	Equus caballus	LDO
CANLF\|Ensembl=ENSCAFG00845027058.1\|UniProtKB=A0A8I3Q066	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000018384.4\|UniProtKB=A0A5F8GDU4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000010939.4\|UniProtKB=A0A6I8NZ28	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012205.1\|UniProtKB=A0A8V0YDG2	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000000035.4\|UniProtKB=G1K865	Anolis carolinensis	LDO
XENLA\|Gene=slc6a13.L\|UniProtKB=Q6PA82	Xenopus laevis	LDO
ORYLA\|Ensembl=ENSORLG00000028327.1\|UniProtKB=A0A3B3IBM5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-061215-110\|UniProtKB=Q1LVI7	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050420-315\|UniProtKB=Q1LVJ1	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050420-179\|UniProtKB=Q1LVI6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050419-161\|UniProtKB=Q1LVI9	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050420-178\|UniProtKB=Q1LVJ0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000014677.1\|UniProtKB=W5NBR8	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000004948.2\|UniProtKB=A0A3B3HKX2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000020091.2\|UniProtKB=H2N0L7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030616-628\|UniProtKB=F1Q5E6	Danio rerio	O
DANRE\|Gene=slc6a13\|UniProtKB=A0A8M2BDD5	Danio rerio	O
DANRE\|Gene=slc6a13l\|UniProtKB=A0A8M2BDC6	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-030616-629\|UniProtKB=Q801U6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012488.1\|UniProtKB=W5N434	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000019043.2\|UniProtKB=H2MXS4	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000001818.2\|UniProtKB=H2L8T4	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000001859.2\|UniProtKB=H2L8Y3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-030131-3729\|UniProtKB=A5D8R6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000012363.1\|UniProtKB=W5N3M2	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000014795.2\|UniProtKB=H2MIR6	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000016855.1\|UniProtKB=W5NJM7	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000030259.1\|UniProtKB=A0A3B3HMK0	Oryzias latipes	O
LEPOC\|Ensembl=ENSLOCG00000012601.1\|UniProtKB=W5N4G3	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000002318.2\|UniProtKB=H2LAG6	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000011499.2\|UniProtKB=H2M7F1	Oryzias latipes	LDO
DANRE\|Gene=LOC100332592\|UniProtKB=A0A8M1REL7	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000016994.1\|UniProtKB=W5NK54	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000004671.3\|UniProtKB=F6QSQ2	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000000123.3\|UniProtKB=F6SIE8	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000006841.3\|UniProtKB=F7AFY1	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000005514.3\|UniProtKB=F6YPI9	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000003845.3\|UniProtKB=F6YPZ5	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000008543.3\|UniProtKB=F6XQ30	Ciona intestinalis	O
BRAFL\|Gene=LOC118415466\|UniProtKB=A0A9J7L4L6	Branchiostoma floridae	O
BRAFL\|Gene=LOC118415465\|UniProtKB=A0A9J7L4V2	Branchiostoma floridae	O
BRAFL\|Gene=LOC118415467\|UniProtKB=A0A9J7L5Y6	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC115919833\|UniProtKB=A0A7M7N4X0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592574\|UniProtKB=A0A7M7HMQ1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115926076\|UniProtKB=A0A7M7T161	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC757159\|UniProtKB=A0A7M7N2B0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100888394\|UniProtKB=A0A7M7N3R5	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC575802\|UniProtKB=A0A7M7N1D2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC592669\|UniProtKB=A0A7M7N237	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115926051\|UniProtKB=A0A7M7P6P4	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC764578\|UniProtKB=A0A7M7MX21	Strongylocentrotus purpuratus	O
IXOSC\|EnsemblGenome=ISCW010973\|UniProtKB=B7Q9C6	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW020974\|UniProtKB=B7Q8Z6	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW016408\|UniProtKB=B7P1X3	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW010971\|UniProtKB=B7Q9C4	Ixodes scapularis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g247614\|UniProtKB=A7SVA2	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG54650\|UniProtKB=B3RSM1	Trichoplax adhaerens	O
EMENI\|EnsemblGenome=ANIA_08966\|UniProtKB=C8VL87	Emericella nidulans	O
PHANO\|EnsemblGenome=SNOG_05834\|UniProtKB=Q0UQY0	Phaeosphaeria nodorum	O
PHANO\|EnsemblGenome=SNOG_04273\|UniProtKB=Q0UVE1	Phaeosphaeria nodorum	O
PLAF7\|EnsemblGenome=PF3D7_0209600\|UniProtKB=O96181	Plasmodium falciparum	O
PLAF7\|EnsemblGenome=PF3D7_1132500\|UniProtKB=Q8II40	Plasmodium falciparum	O
PARTE\|EnsemblGenome=GSPATT00003373001\|UniProtKB=A0DZD7	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003369001\|UniProtKB=A0DZD3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00005033001\|UniProtKB=A0BJE3	Paramecium tetraurelia	O
THEKO\|EnsemblGenome=TK1432\|UniProtKB=Q5JDK2	Thermococcus kodakaraensis	O
LEPIN\|EnsemblGenome=LA_1877\|UniProtKB=Q8F511	Leptospira interrogans	O
AQUAE\|EnsemblGenome=aq_2077\|UniProtKB=O67854	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A0808\|UniProtKB=B5YK84	Thermodesulfovibrio yellowstonii	O