PANTHER Gene Information

Gene Symbol(s):

MLH3

Organism:

Bos taurus

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Tree

Gene Name:

MutL homolog 3

Gene ID:

ENSBTAG00000019279.7

Protein ID:

E1BNK2

Persistent Id:

PTN007419196

Alternate Ids:

ENSBTAT00000061421(Ensembl_TRS)	E1BNK2_BOVIN(UniProtKB-ID)
ENSBTAP00000053506(Ensembl_PRO)	E1BNK2(Synonym)
ENSBTAG00000019279(Ensembl)
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PANTHER Classification

PANTHER Family:	DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL (PTHR10073)
PANTHER Subfamily:	DNA MISMATCH REPAIR PROTEIN MLH3 (PTHR10073:SF47)
PANTHER GO-slim Molecular Function:	ATP hydrolysis activity
PANTHER GO-slim Biological Process:	mismatch repair
PANTHER GO-slim Cellular Component:	protein-containing complex intracellular anatomical structure
PANTHER protein class:	DNA metabolism protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	ATP hydrolysis activity, ATP binding, ATP-dependent DNA damage sensor activity, chromatin binding, mismatched DNA binding, centromeric DNA binding
GO BP Complete:	male meiotic nuclear division, synaptonemal complex assembly, protein localization, female meiosis I, mismatch repair
GO CC Complete:	chiasma, cytoplasm, mismatch repair complex, synaptonemal complex, male germ cell nucleus, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7128\|UniProtKB=Q9UHC1	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006548.7\|UniProtKB=A0A2I3SJ25	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000037041.1\|UniProtKB=A0A2I2ZCB2	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000002911.4\|UniProtKB=A0A5F7ZGI2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1353455\|UniProtKB=A0A1Y7VMP7	Mus musculus	LDO
RAT\|RGD=1309227\|UniProtKB=D4ADG4	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000002378.5\|UniProtKB=A0A286ZR27	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000008011.4\|UniProtKB=F6T592	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000025866.4\|UniProtKB=M3X1R3	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845014944.1\|UniProtKB=A0A8I3NLD8	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000006037.4\|UniProtKB=F6ZUC5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000043220.1\|UniProtKB=A0A6I8NFD7	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010006123.1\|UniProtKB=A0A8V0XKC1	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016842.3\|UniProtKB=G1KT63	Anolis carolinensis	LDO
XENLA\|Gene=mlh3.L\|UniProtKB=A0A8J0TGL1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-991852\|UniProtKB=A0A803JQH8	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016499.2\|UniProtKB=H2MPJ1	Oryzias latipes	LDO
DANRE\|Gene=mlh3\|UniProtKB=A0A8M2B931	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010467.1\|UniProtKB=W5MWS0	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118417722\|UniProtKB=A0A9J7MSF6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC575007\|UniProtKB=A0A7M7PSS1	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115929660\|UniProtKB=A0A7M7T5G4	Strongylocentrotus purpuratus	LDO
TRICA\|EnsemblGenome=TC009474\|UniProtKB=D6WRG1	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_324171\|UniProtKB=E9H0X1	Daphnia pulex	LDO
TRIAD\|EnsemblGenome=TriadG59762\|UniProtKB=B3S6D0	Trichoplax adhaerens	LDO
YEAST\|SGD=S000006085\|UniProtKB=Q12083	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AAL093C\|UniProtKB=Q75F21	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000176790\|UniProtKB=A0A1D8PFX1	Candida albicans	LDO
EMENI\|EnsemblGenome=ANIA_04365\|UniProtKB=Q5B515	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_4G06490\|UniProtKB=Q4WNP5	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU05385\|UniProtKB=Q1K8H7	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_10870\|UniProtKB=A7EZV3	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_04872\|UniProtKB=Q0UTP2	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CND01680\|UniProtKB=Q5KIU9	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_03481\|UniProtKB=A0A0D1C3U8	Ustilago maydis	LDO
ENTH1\|EnsemblGenome=CL6EHI_126120\|UniProtKB=C4LVZ7	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0283883\|UniProtKB=Q54QI0	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_153264\|UniProtKB=F0ZNG3	Dictyostelium purpureum	LDO
TRIV3\|Gene_ORFName=TVAG_352610\|UniProtKB=A2EG63	Trichomonas vaginalis	LDO
CHLRE\|EnsemblGenome=CHLRE_07g336650v5\|UniProtKB=A0A2K3DKA4	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00044p00152780\|UniProtKB=U5D4P3	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_2G02760\|UniProtKB=A0A0K9PDH5	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g07040\|UniProtKB=A0A804L553	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_033402mg\|UniProtKB=K4A3E9	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G290100\|UniProtKB=A0A1B6QDZ8	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb104360\|UniProtKB=A0A804MQJ2	Zea mays	LDO
BRADI\|EnsemblGenome=BRADI_4g37263v3\|UniProtKB=A0A2K2CST3	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0503940\|UniProtKB=K9LZ36	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5B02G355000\|UniProtKB=A0A3B6LS04	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5A02G352800\|UniProtKB=A0A3B6KLK0	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5D02G359800\|UniProtKB=A0A3B6MXX2	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_016472\|UniProtKB=A0A1U8ARF8	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110775240\|UniProtKB=A0A9R0JI32	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr14g0644031\|UniProtKB=A0A251SHR3	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C200076790\|UniProtKB=A0A9R1XVR3	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a002289mg\|UniProtKB=A0A022RI81	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a021714mg\|UniProtKB=A0A022QC19	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_06088\|UniProtKB=A0A2G3A9Q9	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc02g082660.3\|UniProtKB=A0A3Q7FTH2	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107779080\|UniProtKB=A0A1S3YS74	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_04s0044g00170\|UniProtKB=F6I0J7	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J02538\|UniProtKB=A0A059AGU4	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00071478001\|UniProtKB=A0A078HPZ0	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra017718\|UniProtKB=M4DMI3	Brassica campestris	LDO
ARATH\|TAIR=locus=2127923\|UniProtKB=F4JN26	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107937809\|UniProtKB=A0A1U8ML77	Gossypium hirsutum	O
GOSHI\|Gene=LOC107939586\|UniProtKB=A0A1U8MNJ3	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_000060\|UniProtKB=A0A061DF25	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g0005862mg\|UniProtKB=A0A067G7T7	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_005G101900v3\|UniProtKB=A0A2K2AEN2	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_02G114300\|UniProtKB=A0A2C9WDD4	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0874490\|UniProtKB=B9S6V5	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_11G086300\|UniProtKB=A0A0R0HRB2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_01G158400\|UniProtKB=K7K439	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_5g024250\|UniProtKB=G7K187	Medicago truncatula	LDO
JUGRE\|Gene=LOC108984270\|UniProtKB=A0A6P9F6Q5	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G000710\|UniProtKB=A0A0A0L1I8	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_7G183500\|UniProtKB=A0A251NDB3	Prunus persica	LDO
PHYPA\|EnsemblGenome=Pp3c13_10410\|UniProtKB=A0A2K1JLG3	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0006s0222\|UniProtKB=A0A2R6XQ32	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_002620090\|UniProtKB=A0A1Y1I7M7	Klebsormidium nitens	LDO
METAC\|EnsemblGenome=MA_0522\|UniProtKB=Q8TTB5	Methanosarcina acetivorans	O
HALSA\|EnsemblGenome=VNG_0159G\|UniProtKB=Q9HSM6	Halobacterium salinarum	O
CHLAA\|EnsemblGenome=Caur_1133\|UniProtKB=A9WJ86	Chloroflexus aurantiacus	O
CLOBH\|Gene_OrderedLocusName=CBO1799\|UniProtKB=A5I2S1	Clostridium botulinum	O
STRR6\|EnsemblGenome=spr0160\|UniProtKB=P0A3R2	Streptococcus pneumoniae	O
STAA8\|EnsemblGenome=SAOUHSC_01273\|UniProtKB=Q93T05	Staphylococcus aureus	O
LISMO\|EnsemblGenome=CAC99482\|UniProtKB=Q8Y788	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_17050\|UniProtKB=P49850	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_3768\|UniProtKB=Q81A26	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_0022\|UniProtKB=P74925	Thermotoga maritima	O
DEIRA\|EnsemblGenome=DR_1696\|UniProtKB=Q9RTR0	Deinococcus radiodurans	O
GLOVI\|Gene=mutL\|UniProtKB=Q7NL47	Gloeobacter violaceus	O
LEPIN\|EnsemblGenome=LA_1175\|UniProtKB=Q8F6X4	Leptospira interrogans	O
BACTN\|EnsemblGenome=BT_3851\|UniProtKB=Q8A120	Bacteroides thetaiotaomicron	O
CHLTR\|EnsemblGenome=CT_575\|UniProtKB=O84579	Chlamydia trachomatis	O
RHOBA\|EnsemblGenome=RB7883\|UniProtKB=Q7UMZ3	Rhodopirellula baltica	O
AQUAE\|EnsemblGenome=aq_1578\|UniProtKB=O67518	Aquifex aeolicus	O
THEYD\|EnsemblGenome=THEYE_A2083\|UniProtKB=B5YIZ6	Thermodesulfovibrio yellowstonii	O
DICTD\|EnsemblGenome=Dtur_1078\|UniProtKB=B8E280	Dictyoglomus turgidum	O
FUSNN\|EnsemblGenome=FN0462\|UniProtKB=Q8RG56	Fusobacterium nucleatum	O
NEIMB\|EnsemblGenome=NMB1442\|UniProtKB=Q9JYT2	Neisseria meningitidis serogroup b	O
GEOSL\|EnsemblGenome=GSU2001\|UniProtKB=Q74BP0	Geobacter sulfurreducens	O
BRADU\|EnsemblGenome=BAC52758\|UniProtKB=Q89DE6	Bradyrhizobium diazoefficiens	O
COXBU\|EnsemblGenome=CBU_1083\|UniProtKB=Q83CM9	Coxiella burnetii	O
HAEIN\|EnsemblGenome=HI_0067\|UniProtKB=P44494	Haemophilus influenzae	O
SHEON\|Gene_OrderedLocusName=SO_0601\|UniProtKB=Q8EJ70	Shewanella oneidensis	O
VIBCH\|EnsemblGenome=VC_0345\|UniProtKB=Q9KV13	Vibrio cholerae	O
XANCP\|EnsemblGenome=XCC2298\|UniProtKB=Q8P8E4	Xanthomonas campestris	O
PSEAE\|EnsemblGenome=PA4946\|UniProtKB=Q9HUL8	Pseudomonas aeruginosa	O
SALTY\|EnsemblGenome=STM4359\|UniProtKB=P14161	Salmonella typhimurium	O
YERPE\|EnsemblGenome=YP_0527\|UniProtKB=Q8ZIW4	Yersinia pestis	O
ECOLI\|EnsemblGenome=BAE78171\|UniProtKB=P23367	Escherichia coli	O