PANTHER Gene Information

Gene Symbol(s):

UBR1

Organism:

Bos taurus

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Tree

Gene Name:

E3 ubiquitin-protein ligase

Gene ID:

ENSBTAG00000021087.5

Protein ID:

E1BIW0

Persistent Id:

PTN000487023

Alternate Ids:

E1BIW0_BOVIN(UniProtKB-ID)	ENSBTAT00000028086(Ensembl_TRS)
NM_001205897(refSeq)	ENSBTAP00000028086(Ensembl_PRO)
E1BIW0(Synonym)	ENSBTAG00000021087(Ensembl)
522464(GeneID)
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PANTHER Classification

PANTHER Family:	UBIQUITIN LIGASE E3 ALPHA-RELATED (PTHR21497)
PANTHER Subfamily:	E3 UBIQUITIN-PROTEIN LIGASE UBR1 (PTHR21497:SF27)
PANTHER GO-slim Molecular Function:	ubiquitin protein ligase activity
PANTHER GO-slim Biological Process:	proteasome-mediated ubiquitin-dependent protein catabolic process protein ubiquitination
PANTHER GO-slim Cellular Component:	ubiquitin ligase complex cytoplasm
PANTHER protein class:	ubiquitin-protein ligase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	L-leucine binding, zinc ion binding, ubiquitin protein ligase activity
GO BP Complete:	cellular response to L-leucine, ubiquitin-dependent protein catabolic process via the N-end rule pathway, negative regulation of TOR signaling, protein ubiquitination
GO CC Complete:	ubiquitin ligase complex, cytoplasm, cytosol, proteasome complex

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Adaptive Immune System, Immune System, Antigen processing: Ubiquitination & Proteasome degradation, Class I MHC mediated antigen processing & presentation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=16808\|UniProtKB=Q8IWV7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000006985.5\|UniProtKB=H2Q9A0	Pan troglodytes	LDO
MACMU\|Ensembl=ENSMMUG00000006498.4\|UniProtKB=G7MWZ8	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1277977\|UniProtKB=O70481	Mus musculus	LDO
RAT\|RGD=1562326\|UniProtKB=A0A8I5ZZN6	Rattus norvegicus	LDO
PIG\|Ensembl=ENSSSCG00000004717.5\|UniProtKB=A0A286ZPW1	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011972.3\|UniProtKB=A0A9L0R545	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000002426.6\|UniProtKB=M3VYG9	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845021765.1\|UniProtKB=A0A8I3P974	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000017858.4\|UniProtKB=F6YIN6	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000048157.1\|UniProtKB=A0A6I8NJ57	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010020775.1\|UniProtKB=A0A8V0ZM17	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000015852.4\|UniProtKB=G1KRV4	Anolis carolinensis	LDO
XENLA\|Gene=ubr1.L\|UniProtKB=A0A8J0TKT2	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-6052364\|UniProtKB=A0A7D9N0A0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016076.3\|UniProtKB=H2MN21	Oryzias latipes	LDO
DANRE\|Gene=ubr1\|UniProtKB=A0A8M9P0T8	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012945.1\|UniProtKB=W5N5P7	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118415974\|UniProtKB=A0A9J7L684	Branchiostoma floridae	O
STRPU\|EnsemblGenome=LOC591135\|UniProtKB=A0A7M7PQ30	Strongylocentrotus purpuratus	O
CAEEL\|WormBase=WBGene00016326\|UniProtKB=P91133	Caenorhabditis elegans	O
CAEBR\|Gene_ORFName=CBG12009\|UniProtKB=A8XEC1	Caenorhabditis briggsae	O
PRIPA\|EnsemblGenome=WBGene00274118\|UniProtKB=A0A2A6BN62	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0030809\|UniProtKB=Q9VX91	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP000171\|UniProtKB=A0A1S4G8A2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC007434\|UniProtKB=D1ZZM2	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_314139\|UniProtKB=E9G4S3	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW021163\|UniProtKB=B7Q7W6	Ixodes scapularis	O
HELRO\|EnsemblGenome=HelroG188532\|UniProtKB=T1FQ36	helobdella robusta	O
TRIAD\|EnsemblGenome=TriadG57299\|UniProtKB=B3RZ22	Trichoplax adhaerens	O
MONBE\|EnsemblGenome=MONBRDRAFT_26292\|UniProtKB=A9V1Y2	Monosiga brevicollis	O
YEAST\|SGD=S000003416\|UniProtKB=P19812	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AAL146W\|UniProtKB=Q75F74	Eremothecium gossypii	O
CANAL\|CGD=CAL0000198590\|UniProtKB=A0A1D8PLP8	Candida albicans	O
YEAST\|SGD=S000004014\|UniProtKB=Q07963	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AAL147C\|UniProtKB=Q75F75	Eremothecium gossypii	O
CANAL\|CGD=CAL0000189170\|UniProtKB=Q5AFB1	Candida albicans	O
YARLI\|EnsemblGenome=YALI0_B03718g\|UniProtKB=Q6CFU4	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_01995\|UniProtKB=Q5BBT5	Emericella nidulans	O
NEUCR\|EnsemblGenome=NCU02609\|UniProtKB=V5IP88	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_06196\|UniProtKB=A7ELJ9	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_14214\|UniProtKB=Q0U252	Phaeosphaeria nodorum	O
EMENI\|EnsemblGenome=ANIA_03923\|UniProtKB=Q5B6A7	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G08420\|UniProtKB=Q4WMX1	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU03234\|UniProtKB=Q7SGT6	Neurospora crassa	O
PHANO\|EnsemblGenome=SNOG_03164\|UniProtKB=Q0UYK0	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPAC15A10.11\|UniProtKB=O13731	Schizosaccharomyces pombe	O
SCHPO\|PomBase=SPBC19C7.02\|UniProtKB=O60152	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_01253\|UniProtKB=B6K064	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNE03650\|UniProtKB=Q5KGG9	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_00067\|UniProtKB=A0A0D1EBB2	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_00883\|UniProtKB=E3JU27	Puccinia graminis	O
BATDJ\|Gene_ORFName=BATDEDRAFT_21290\|UniProtKB=F4NS80	Batrachochytrium dendrobatidis	O
ENTH1\|EnsemblGenome=EHI_141950\|UniProtKB=C4LW41	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_018590\|UniProtKB=B1N4N9	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_114110\|UniProtKB=C4M418	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_050540\|UniProtKB=C4LTS7	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_119940\|UniProtKB=C4M988	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_030770\|UniProtKB=C4M1E6	Entamoeba histolytica	O
DICDI\|dictyBase=DDB_G0276047\|UniProtKB=Q75JM9	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_156662\|UniProtKB=F0ZX35	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0288473\|UniProtKB=Q54IW6	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_47201\|UniProtKB=F0ZI95	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0292128\|UniProtKB=Q54DM4	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_149555\|UniProtKB=F0ZE25	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0287859\|UniProtKB=Q54JV0	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0288093\|UniProtKB=Q54JE9	Dictyostelium discoideum	O
DICDI\|dictyBase=DDB_G0287799\|UniProtKB=Q54JT8	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_86584\|UniProtKB=F0ZCM2	Dictyostelium purpureum	O
DICDI\|dictyBase=DDB_G0283475\|UniProtKB=Q54QZ3	Dictyostelium discoideum	O
DICPU\|EnsemblGenome=DICPUDRAFT_95779\|UniProtKB=F1A0M7	Dictyostelium purpureum	O
LEIMA\|EnsemblGenome=LMJF_09_0740\|UniProtKB=Q4QHV0	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.4620\|UniProtKB=Q382Q4	Trypanosoma brucei	O
GIAIC\|EnsemblGenome=GL50803_13708\|UniProtKB=A8BU27	Giardia intestinalis	O
THAPS\|EnsemblGenome=THAPSDRAFT_22947\|UniProtKB=B8C4U6	Thalassiosira pseudonana	O
THAPS\|EnsemblGenome=THAPSDRAFT_23971\|UniProtKB=B8C846	Thalassiosira pseudonana	O
PHYRM\|Gene=H3GCV5_PHYRM\|UniProtKB=H3GCV5	Phytophthora ramorum	O
PHYRM\|Gene=H3GZ80_PHYRM\|UniProtKB=H3GZ80	Phytophthora ramorum	O
CHLRE\|EnsemblGenome=CHLRE_02g089237v5\|UniProtKB=A0A2K3E150	Chlamydomonas reinhardtii	O
AMBTC\|EnsemblGenome=AMTR_s00012p00210330\|UniProtKB=W1PL49	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_88G00290\|UniProtKB=A0A0K9NKB8	Zostera marina	O
MUSAM\|EnsemblGenome=Ma06_g16780\|UniProtKB=A0A804JH24	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_000008mg\|UniProtKB=K3XDP1	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3003G072200\|UniProtKB=C5XPZ8	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb124390\|UniProtKB=A0A804N011	Zea mays	O
BRADI\|EnsemblGenome=BRADI_2g03180v3\|UniProtKB=I1HC05	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0230290\|UniProtKB=A0A8I6XPW3	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS3A02G072400\|UniProtKB=A0A3B6EAQ8	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.3HG0230560\|UniProtKB=A0A287K517	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS3B02G087600\|UniProtKB=A0A077RA92	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3A02G073400\|UniProtKB=A0A3B6EAJ8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS3D02G073100\|UniProtKB=A0A3B6GML9	Triticum aestivum	O
NELNU\|Gene=LOC104597194\|UniProtKB=A0A1U7ZRR5	Nelumbo nucifera	O
SPIOL\|Gene=LOC110791994\|UniProtKB=A0A9R0INM7	Spinacia oleracea	O
HELAN\|Gene_ORFName=HannXRQ_Chr06g0177081\|UniProtKB=A0A251UHV1	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0258221\|UniProtKB=A0A251UJ91	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr06g0258281\|UniProtKB=A0A9K3NIY9	Helianthus annuus	O
HELAN\|Gene_ORFName=HanXRQr2_Chr04g0187651\|UniProtKB=A0A9K3JBV7	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr04g0125101\|UniProtKB=A0A251V260	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C800422070\|UniProtKB=A0A9R1WXB0	Lactuca sativa	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a000061mg\|UniProtKB=A0A022QJB7	Erythranthe guttata	O
CAPAN\|EnsemblGenome=T459_25961\|UniProtKB=A0A2G2YM82	Capsicum annuum	O
SOLLC\|EnsemblGenome=Solyc10g084760.2\|UniProtKB=A0A3Q7INH7	Solanum lycopersicum	O
TOBAC\|Gene=LOC107829718\|UniProtKB=A0A1S4DHD0	Nicotiana tabacum	O
SOLLC\|EnsemblGenome=Solyc09g010830.3\|UniProtKB=A0A3Q7IU45	Solanum lycopersicum	O
TOBAC\|Gene=LOC107797361\|UniProtKB=A0A1S4AG98	Nicotiana tabacum	O
TOBAC\|Gene=LOC107820058\|UniProtKB=A0A1S4CKJ0	Nicotiana tabacum	O
VITVI\|Gene_OrderedLocusName=VIT_08s0007g00380\|UniProtKB=F6HLC4	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_A01266\|UniProtKB=A0A059DDY7	Eucalyptus grandis	O
BRANA\|Gene_ORFName=GSBRNA2T00088793001\|UniProtKB=A0A078IFL3	Brassica napus	O
BRACM\|EnsemblGenome=Bra028876\|UniProtKB=M4EJB0	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_A03P00630.1\|UniProtKB=A0A078IYR1	Brassica napus	O
BRACM\|EnsemblGenome=Bra005717\|UniProtKB=M4CNC9	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C09P74230.1\|UniProtKB=A0A078FBT5	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A10P33320.1\|UniProtKB=A0A078HU99	Brassica napus	O
BRACM\|EnsemblGenome=Bra009598\|UniProtKB=M4CZF1	Brassica campestris	O
ARATH\|TAIR=locus=2180147\|UniProtKB=F4KCC2	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107891054\|UniProtKB=A0A1U8HYU4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107919814\|UniProtKB=A0A1U8KVA0	Gossypium hirsutum	O
GOSHI\|Gene=LOC107939925\|UniProtKB=A0A1U8MTE5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107893857\|UniProtKB=A0A1U8I8A1	Gossypium hirsutum	O
GOSHI\|Gene=LOC107958010\|UniProtKB=A0A1U8PDC2	Gossypium hirsutum	O
GOSHI\|Gene=LOC107889688\|UniProtKB=A0A1U8HUL3	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_021934\|UniProtKB=A0A061ESZ0	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g000141mg\|UniProtKB=A0A067DM97	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_006G085700v3\|UniProtKB=A0A2K1ZZ22	Populus trichocarpa	O
RICCO\|Gene_ORFName=RCOM_0915870\|UniProtKB=B9T256	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_18G181200\|UniProtKB=I1N2H2	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_07G132300\|UniProtKB=I1KJZ0	Glycine max	O
MEDTR\|EnsemblGenome=MTR_7g061540\|UniProtKB=G7L5H7	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr04_02850\|UniProtKB=A0A2I4GCY7	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_3G734220\|UniProtKB=A0A0A0LD61	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_6G255500\|UniProtKB=A0A251NVV7	Prunus persica	O
SELML\|EnsemblGenome=SELMODRAFT_438209\|UniProtKB=D8QV21	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_79007\|UniProtKB=D8QU62	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c3_37220\|UniProtKB=A0A7I4DEV2	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c10_20380\|UniProtKB=A0A7I4A8R1	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c8_2930\|UniProtKB=A0A7I4EEX4	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c3_24510\|UniProtKB=A0A7I4DAV0	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0123s0014\|UniProtKB=A0A2R6W9J6	Marchantia polymorpha	O
PHYPA\|EnsemblGenome=Pp3c2_29090\|UniProtKB=A0A7I4D2J3	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c17_2850\|UniProtKB=A0A7I4BJ62	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c9_4700\|UniProtKB=A0A7I4FWC6	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c15_3560\|UniProtKB=A0A7I4F5V8	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c7_22570\|UniProtKB=A0A7I4E713	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0028s0055\|UniProtKB=A0A2R6X9F8	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_003380050\|UniProtKB=A0A1Y1I8D2	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_003640090\|UniProtKB=A0A1Y1IFU1	Klebsormidium nitens	O