PANTHER Gene Information

Gene Symbol(s):

dkf-2

Organism:

Caenorhabditis briggsae

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Gene Name:

Serine_threonine-protein kinase dkf-2

Gene ID:

CBG17105

Protein ID:

A8XQD5

Persistent Id:

PTN002344262

Alternate Ids:

CBG17105a(WormBase_TRS)	CBP46891(WormBase_PRO)
HE601529(EMBL)	D kinase family-2 {ECO:0000250\|UniProtKB:O45818}(Synonym)
259645269(GI)	2.7.11.13(EC)
DKF2_CAEBR(UniProtKB-ID)	CAP34861(EMBL-CDS)
dkf-2{ECO:0000312\|EMBL:CAP34861.2}(Symbol)	WBGene00036856(WormBase)
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PANTHER Classification

PANTHER Family:	PROTEIN KINASE C, MU (PTHR22968)
PANTHER Subfamily:	SERINE_THREONINE-PROTEIN KINASE (PTHR22968:SF24)
PANTHER GO-slim Molecular Function:	protein serine/threonine kinase activity
PANTHER GO-slim Biological Process:	phospholipase C-activating G protein-coupled receptor signaling pathway intracellular signal transduction
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	non-receptor serine/threonine protein kinase

Pathway Categories:

VEGF signaling pathway

Protein kinase C

Angiogenesis

Protein kinase B

EGF receptor signaling pathway

PKC

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity, ATP binding, metal ion binding, protein kinase activity, protein serine/threonine kinase activity, calcium,diacylglycerol-dependent serine/threonine kinase activity, protein serine kinase activity
GO BP Complete:	innate immune response, phospholipase C-activating G protein-coupled receptor signaling pathway, intracellular signal transduction
GO CC Complete:	cytoplasm, membrane, cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=17293\|UniProtKB=Q9BZL6	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000011190.4\|UniProtKB=K7DN39	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000010508.3\|UniProtKB=A0A2I2ZRU3	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000017927.4\|UniProtKB=F7ES71	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2141917\|UniProtKB=Q8BZ03	Mus musculus	LDO
RAT\|RGD=1308054\|UniProtKB=Q5XIS9	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000015599.6\|UniProtKB=F1MIA2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000026152.3\|UniProtKB=I3L9Z3	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000024775.3\|UniProtKB=F6RMS9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000010311.6\|UniProtKB=M3WD27	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845003382.1\|UniProtKB=A0A8I3MQ74	Canis lupus familiaris	LDO
ORNAN\|Ensembl=ENSOANG00000049147.1\|UniProtKB=A0A6I8PFL3	Ornithorhynchus anatinus	LDO
ORYLA\|Ensembl=ENSORLG00000007121.2\|UniProtKB=A0A3B3H6M1	Oryzias latipes	LDO
DANRE\|Gene=prkd2\|UniProtKB=A0A8M9PLD4	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000014916.1\|UniProtKB=W5NCL0	lepisosteus oculatus	LDO
HUMAN\|HGNC=9407\|UniProtKB=Q15139	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000006232.6\|UniProtKB=H2Q845	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011852.3\|UniProtKB=G3R862	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000022550.4\|UniProtKB=F6Y9I6	Macaca mulatta	O
MOUSE\|MGI=MGI=99879\|UniProtKB=Q62101	Mus musculus	O
RAT\|RGD=620964\|UniProtKB=Q9WTQ1	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000012789.6\|UniProtKB=F1MWF5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000001975.5\|UniProtKB=A0A287BDY7	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000005719.4\|UniProtKB=A0A9L0T090	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000014491.6\|UniProtKB=A0A2I2U3H7	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845009533.1\|UniProtKB=A0A8I3RVC8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000017552.4\|UniProtKB=F7E0Y0	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000014018.3\|UniProtKB=A0A6I8NYH7	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010005458.1\|UniProtKB=A0A8V0XU96	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000015972.4\|UniProtKB=G1KS05	Anolis carolinensis	O
XENLA\|Gene=prkd3.L\|UniProtKB=A0A1L8GK22	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-6036037\|UniProtKB=A0A6I8QVJ5	Xenopus tropicalis	O
XENLA\|Gene=prkd1.S\|UniProtKB=A0A1L8EZL7	Xenopus laevis	O
XENLA\|Gene=prkd1.L\|UniProtKB=A0A8J1LI84	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-487626\|UniProtKB=B2GU99	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000010716.2\|UniProtKB=A0A3B3IJ88	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-080131-1\|UniProtKB=X1WHC7	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000009700.1\|UniProtKB=W5MTZ8	lepisosteus oculatus	O
HUMAN\|HGNC=9408\|UniProtKB=O94806	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000011838.4\|UniProtKB=H2QHR7	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000016914.3\|UniProtKB=G3RL70	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000016438.4\|UniProtKB=A0A1D5QG47	Macaca mulatta	O
MOUSE\|MGI=MGI=1922542\|UniProtKB=Q8K1Y2	Mus musculus	O
RAT\|RGD=1310236\|UniProtKB=D4A229	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000001114.4\|UniProtKB=E1B7L9	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000008495.5\|UniProtKB=A0A287B7B6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000008642.3\|UniProtKB=F6Q0W4	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000015768.6\|UniProtKB=M3WN89	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845019448.1\|UniProtKB=A0A8I3P9H8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000008318.4\|UniProtKB=F7FGD2	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000003940.4\|UniProtKB=F6U161	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010007141.1\|UniProtKB=E1C6T4	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000001139.4\|UniProtKB=G1K9B8	Anolis carolinensis	O
ORYLA\|Ensembl=ENSORLG00000008092.2\|UniProtKB=H2LVM7	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-080204-93\|UniProtKB=A9JTH6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000001570.1\|UniProtKB=W5M0A0	lepisosteus oculatus	O
ORYLA\|Ensembl=ENSORLG00000018118.2\|UniProtKB=H2MV64	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000017403.2\|UniProtKB=H2MSM5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-130530-880\|UniProtKB=E7F9Z2	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000016864.1\|UniProtKB=W5NJN7	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000008839.3\|UniProtKB=A0A1W2WK21	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000005266.3\|UniProtKB=F6V8A8	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118424135\|UniProtKB=A0A9J7LTX6	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115919090\|UniProtKB=A0A7M7PTB7	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00012019\|UniProtKB=O45818	Caenorhabditis elegans	LDO
PRIPA\|EnsemblGenome=WBGene00102183\|UniProtKB=A0A2A6CRS3	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0038603\|UniProtKB=A0A0B4KHC3	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP000070\|UniProtKB=Q7PS40	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC009940\|UniProtKB=A0A139WES9	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_308512\|UniProtKB=E9G2E3	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG115447\|UniProtKB=T1EG82	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG168571\|UniProtKB=T1F0R0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g104852\|UniProtKB=A7S4Z5	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG30089\|UniProtKB=B3S6K4	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_34784\|UniProtKB=A9VE23	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_25110\|UniProtKB=A9UYF8	Monosiga brevicollis	O