PANTHER Gene Information

Gene Symbol(s):

ced-8

Organism:

Caenorhabditis briggsae

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Gene Name:

Cell death abnormality protein 8

Gene ID:

WBGene00041249

Protein ID:

A8Y2U2

Persistent Id:

PTN002312875

Alternate Ids:

8587507(GeneID)	XP_002645508(refSeq)
CBP20492(WormBase_PRO)	WBGene00041249(WormBase)
CBG22761(Ensembl_PRO)	CBG22761(WormBase_TRS)
CBG22761(Ensembl_TRS)	ced-8{ECO:0000312\|EMBL:CAP39278.1}(Symbol)
CAP39278(EMBL-CDS)	CED8(Synonym)
WBGene00041249(Ensembl)	HE601156(EMBL)
CED8_CAEBR(UniProtKB-ID)	268581051(GI)
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PANTHER Classification

PANTHER Family:	XK-RELATED PROTEIN (PTHR16024)
PANTHER Subfamily:	XK-RELATED PROTEIN (PTHR16024:SF6)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	secondary carrier transporter

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	phospholipid scramblase activity
GO BP Complete:	phosphatidylserine exposure on apoptotic cell surface, embryo development ending in birth or egg hatching, apoptotic process, engulfment of apoptotic cell, apoptotic process involved in development, programmed cell death, execution phase of apoptosis
GO CC Complete:	membrane, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=25508\|UniProtKB=Q9H6D3	Homo sapiens	LDO
PANTR\|Gene=XKR8\|UniProtKB=Q49LS0	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000000422.6\|UniProtKB=K7BJ74	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000014917.3\|UniProtKB=G3RG17	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000054886.1\|UniProtKB=A0A5F8AN23	Macaca mulatta	LDO
MOUSE\|MGI=MGI=2685877\|UniProtKB=Q8C0T0	Mus musculus	LDO
RAT\|RGD=1305649\|UniProtKB=Q5GH55	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000008800.5\|UniProtKB=E1BD69	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000030623.4\|UniProtKB=F1STN1	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000034139.3\|UniProtKB=A0A2I2U9E5	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845011047.1\|UniProtKB=A0A8I3NGB4	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000010757.3\|UniProtKB=F7FWH7	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000036599.1\|UniProtKB=A0A6I8NIW5	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012773.1\|UniProtKB=A0A8V0YIW8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000044728.1\|UniProtKB=A0A803U1C2	Anolis carolinensis	LDO
XENLA\|Gene=xkr8.S\|UniProtKB=A0A1L8H7P9	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-940182\|UniProtKB=A0A6I8PSE6	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009399.2\|UniProtKB=H2M061	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-110106-2\|UniProtKB=I3IS75	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-120215-27\|UniProtKB=E7F1M2	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-110106-1\|UniProtKB=E7F2E5	Danio rerio	O
DANRE\|Gene=LOC100148479\|UniProtKB=A0A8M1QR63	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000009411.2\|UniProtKB=H2M075	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-041010-107\|UniProtKB=B7ZVS9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004211.1\|UniProtKB=W5M9H4	lepisosteus oculatus	LDO
HUMAN\|HGNC=29394\|UniProtKB=Q5GH76	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000020257.4\|UniProtKB=A0A2J8L4Z3	Pan troglodytes	O
PANTR\|Gene=XKR4Q5GH76\|UniProtKB=Q49LS4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000025035.2\|UniProtKB=G3RZJ5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000003733.4\|UniProtKB=F6S0I2	Macaca mulatta	O
MOUSE\|MGI=MGI=3528744\|UniProtKB=Q5GH67	Mus musculus	O
RAT\|RGD=1549780\|UniProtKB=Q5GH59	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000044050.3\|UniProtKB=E1BNK0	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000031813.3\|UniProtKB=A0A287BHR6	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000006978.4\|UniProtKB=A0A3Q2HYY1	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000008909.4\|UniProtKB=M3WAG1	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845026228.1\|UniProtKB=A0A8I3PNE4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000025611.3\|UniProtKB=F6QBD7	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000048684.1\|UniProtKB=A0A6I8PE62	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010004583.1\|UniProtKB=A0A8V0XDG3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000017979.2\|UniProtKB=H9GPX9	Anolis carolinensis	O
XENLA\|Gene=xkr4.S\|UniProtKB=A0A8J0T6Z4	Xenopus laevis	O
XENLA\|Gene=xkr4.L\|UniProtKB=A0A1L8FZ08	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-5813487\|UniProtKB=Q4VV72	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000004273.2\|UniProtKB=H2LH92	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-051030-45\|UniProtKB=Q5GH42	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000005543.1\|UniProtKB=W5ME82	lepisosteus oculatus	O
HUMAN\|HGNC=23062\|UniProtKB=Q5GH72	Homo sapiens	O
PANTR\|Gene=XKR7\|UniProtKB=Q49LS1	Pan troglodytes	O
PANTR\|Ensembl=ENSPTRG00000013369.6\|UniProtKB=H2RAY0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000005244.3\|UniProtKB=G3QR93	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000061404.1\|UniProtKB=A0A5F7ZFA2	Macaca mulatta	O
MOUSE\|MGI=MGI=3526711\|UniProtKB=Q5GH64	Mus musculus	O
RAT\|RGD=1359224\|UniProtKB=Q5GH56	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000016348.4\|UniProtKB=E1BQ05	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000007238.5\|UniProtKB=F1S527	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000013313.3\|UniProtKB=F6ZP62	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000024579.4\|UniProtKB=M3WTJ6	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845020174.1\|UniProtKB=A0A8I3PCE0	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000019477.3\|UniProtKB=F6RB74	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000044482.1\|UniProtKB=A0A6I8P571	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010015626.1\|UniProtKB=A0A8V0YSZ7	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000017051.3\|UniProtKB=H9GNW0	Anolis carolinensis	O
XENLA\|Gene=xkr7.L\|UniProtKB=A0A1L8ETD8	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000047648\|UniProtKB=A0A803JYC8	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000014885.2\|UniProtKB=H2MJ27	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-091214-2\|UniProtKB=Q5GH39	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000016735.2\|UniProtKB=A0A3B3HKD3	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-051113-336\|UniProtKB=Q32PW6	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000005415.1\|UniProtKB=W5MDS4	lepisosteus oculatus	O
HUMAN\|HGNC=27806\|UniProtKB=Q5GH73	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000048764.1\|UniProtKB=A0A2I3SG91	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000009379.3\|UniProtKB=G3R1T2	Gorilla gorilla gorilla	O
MOUSE\|MGI=MGI=2447765\|UniProtKB=E9Q6C8	Mus musculus	O
RAT\|RGD=1310719\|UniProtKB=Q5GH57	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000005396.6\|UniProtKB=E1BAR7	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000009693.5\|UniProtKB=F1RJ21	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000013778.3\|UniProtKB=A0A3Q2KP89	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000023785.3\|UniProtKB=M3XE60	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845019774.1\|UniProtKB=A0A8I3PHZ3	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000008911.3\|UniProtKB=F7GL92	Monodelphis domestica	O
CHICK\|Ensembl=ENSGALG00010011213.1\|UniProtKB=A0A8V0YA18	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000007641.2\|UniProtKB=H9GCV7	Anolis carolinensis	O
XENLA\|Gene=xkr6.S\|UniProtKB=A0A1L8G5K7	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-983572\|UniProtKB=F7E7U4	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000030344.1\|UniProtKB=A0A3B3INL6	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040724-153\|UniProtKB=F1R8C3	Danio rerio	O
ORYLA\|Ensembl=ENSORLG00000004398.2\|UniProtKB=H2LHQ2	Oryzias latipes	O
DANRE\|Gene=xkr6a\|UniProtKB=A0A8M6YVQ0	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000015830.1\|UniProtKB=W5NFS8	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000024342.1\|UniProtKB=H2Y093	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118410598\|UniProtKB=A0A9J7MI45	Branchiostoma floridae	O
BRAFL\|Gene=LOC118410439\|UniProtKB=A0A9J7MHW0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118408238\|UniProtKB=A0A9J7HRW8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC584982\|UniProtKB=A0A7M7HDN3	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC584966\|UniProtKB=A0A7M7NTU0	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00000422\|UniProtKB=O17386	Caenorhabditis elegans	LDO
PRIPA\|EnsemblGenome=WBGene00110140\|UniProtKB=A0A2A6D395	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0034279\|UniProtKB=A1ZAZ7	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP002299\|UniProtKB=Q7QBT4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC013535\|UniProtKB=D6WL02	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC031980\|UniProtKB=A0A139WNJ8	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC004531\|UniProtKB=D6WAQ5	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_194459\|UniProtKB=E9G7H4	Daphnia pulex	O
IXOSC\|EnsemblGenome=ISCW019345\|UniProtKB=B7PU67	Ixodes scapularis	O
DROME\|FlyBase=FBgn0052579\|UniProtKB=M9PHA4	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP000599\|UniProtKB=A0A1S4GA27	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC008975\|UniProtKB=D6WQ44	Tribolium castaneum	LDO
TRICA\|EnsemblGenome=TC009223\|UniProtKB=D6WSU8	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_312000\|UniProtKB=E9FYJ4	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_302666\|UniProtKB=E9GXW2	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_324882\|UniProtKB=E9H318	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_323100\|UniProtKB=E9GXW9	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_43071\|UniProtKB=E9FYJ5	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW011441\|UniProtKB=B7Q9I0	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW010549\|UniProtKB=B7Q5Y7	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW007506\|UniProtKB=B7PVK9	Ixodes scapularis	O
IXOSC\|EnsemblGenome=ISCW011440\|UniProtKB=B7Q9H9	Ixodes scapularis	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g98457\|UniProtKB=A7RYY6	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g222848\|UniProtKB=A7T641	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g215456\|UniProtKB=A7SPK7	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g203370\|UniProtKB=A7RWX4	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g217403\|UniProtKB=A7STT9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g110646\|UniProtKB=A7SA49	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG58072\|UniProtKB=B3S2L9	Trichoplax adhaerens	LDO
TRIAD\|EnsemblGenome=TriadG58071\|UniProtKB=B3S2L8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG57933\|UniProtKB=B3S257	Trichoplax adhaerens	O
PHYPA\|EnsemblGenome=Pp3c1_38580\|UniProtKB=A0A2K1LBF1	Physcomitrella patens	LDO