PANTHER Gene Information

Gene Symbol(s):

hlh-1

Organism:

Caenorhabditis elegans

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Gene Name:

Myoblast determination protein 1 homolog

Gene ID:

WBGene00001948

Protein ID:

P22980

Persistent Id:

PTN000164965

Alternate Ids:

CE31766(WormBase_PRO)	B0304.1a(WormBase_TRS)
173788(GeneID)	WBGene00001948(WormBase)
NP_494798(refSeq)	MYOD1_CAEEL(UniProtKB-ID)
WBGene00001948(Ensembl)	1346634(GI)
CCD61732(EMBL-CDS)	M59940(EMBL)
MYOD1(Synonym)	hlh-1{ECO:0000312\|WormBase:B0304.1b}(Symbol)
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PANTHER Classification

PANTHER Family:	MYOGENIC FACTOR (PTHR11534)
PANTHER Subfamily:	MYOGENIC-DETERMINATION PROTEIN (PTHR11534:SF9)
PANTHER GO-slim Molecular Function:	RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific
PANTHER GO-slim Biological Process:	regulation of transcription by RNA polymerase II positive regulation of cell differentiation
PANTHER GO-slim Cellular Component:
PANTHER protein class:	basic helix-loop-helix transcription factor

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	DNA binding, DNA-binding transcription factor activity, protein homodimerization activity, RNA polymerase II cis-regulatory region sequence-specific DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, protein dimerization activity, DNA-binding transcription factor activity, RNA polymerase II-specific
GO BP Complete:	muscle organ development, striated muscle cell differentiation, cell differentiation, regulation of DNA-templated transcription, positive regulation of myoblast differentiation, positive regulation of mesodermal cell fate specification, positive regulation of transcription by RNA polymerase II, positive regulation of muscle cell differentiation, regulation of transcription by RNA polymerase II
GO CC Complete:	nucleus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Myogenesis, Developmental Biology

Orthologs

ID	Organism	Type
HUMAN\|HGNC=7566\|UniProtKB=P23409	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000005260.3\|UniProtKB=H2Q6J2	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000004369.3\|UniProtKB=G3QP01	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000011667.3\|UniProtKB=F7HGT9	Macaca mulatta	O
MOUSE\|MGI=MGI=97253\|UniProtKB=P15375	Mus musculus	O
RAT\|RGD=3134\|UniProtKB=P19335	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000014003\|UniProtKB=Q7YS80	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000026533\|UniProtKB=Q3YFL6	Sus scrofa	O
FELCA\|Ensembl=ENSFCAG00000015010.4\|UniProtKB=M3WLS1	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845009704.1\|UniProtKB=A0A8I3N246	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000039074.1\|UniProtKB=A0A5F8GZT0	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000004854.4\|UniProtKB=F7DJU2	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010012253\|UniProtKB=Q01795	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000042468.1\|UniProtKB=A0A803TTJ0	Anolis carolinensis	O
XENLA\|Gene=myf6\|UniProtKB=Q92020	Xenopus laevis	O
XENLA\|Gene=myf6.L\|UniProtKB=A0A8J1MHR7	Xenopus laevis	O
XENLA\|Gene=myf6.S\|UniProtKB=Q5U4S0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-998203\|UniProtKB=A0A6I8PJV1	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000016261.2\|UniProtKB=H2MNQ1	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-040309-2\|UniProtKB=Q6VNZ9	Danio rerio	O
HUMAN\|HGNC=7565\|UniProtKB=P13349	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000005261.4\|UniProtKB=H2Q6J3	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000004366.3\|UniProtKB=G3QNZ9	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000011669.4\|UniProtKB=F7HGT7	Macaca mulatta	LDO
MOUSE\|MGI=MGI=97252\|UniProtKB=P24699	Mus musculus	LDO
RAT\|RGD=1308322\|UniProtKB=D3ZVU3	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000026972\|UniProtKB=P17667	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000000937.4\|UniProtKB=A0A5G2QML5	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000020047.4\|UniProtKB=F7BTN2	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000015011.5\|UniProtKB=M3WLS2	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845009734.1\|UniProtKB=A0A8I3N278	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000020478.3\|UniProtKB=F7FIX4	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000004853.4\|UniProtKB=F7DJV8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010012264.1\|UniProtKB=A0A8V0YDQ4	Gallus gallus	O
CHICK\|Gene=MYF5\|UniProtKB=Q08856	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000014431.4\|UniProtKB=G1KPV6	Anolis carolinensis	LDO
XENLA\|Gene=myf5\|UniProtKB=P24700	Xenopus laevis	O
XENLA\|Gene=myf5.S\|UniProtKB=A0A1L8GUT4	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-493550\|UniProtKB=Q8QG50	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000016257.2\|UniProtKB=H2MNP6	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-000616-6\|UniProtKB=Q9DDW0	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000002142.1\|UniProtKB=W5M281	lepisosteus oculatus	O
LEPOC\|Ensembl=ENSLOCG00000016302.1\|UniProtKB=W5NHL0	lepisosteus oculatus	LDO
HUMAN\|HGNC=7612\|UniProtKB=P15173	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000001866.4\|UniProtKB=H2R2K4	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000002115.3\|UniProtKB=G3QI77	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000043626.2\|UniProtKB=A0A5F8A6G3	Macaca mulatta	O
MOUSE\|MGI=MGI=97276\|UniProtKB=P12979	Mus musculus	O
RAT\|RGD=620432\|UniProtKB=P20428	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000006030\|UniProtKB=Q7YS81	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000034654.3\|UniProtKB=A0A5S6HX62	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00005039937\|UniProtKB=P49812	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000015955.3\|UniProtKB=F6VR29	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000034593.3\|UniProtKB=A0A2I2U9I7	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845014215.1\|UniProtKB=A0A8I3NSP2	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000001009.3\|UniProtKB=F6ZFK9	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000002107.3\|UniProtKB=F6UM04	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010025215.1\|UniProtKB=A0A8V1A9D6	Gallus gallus	O
CHICK\|Gene=MYOG\|UniProtKB=P17920	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000004818.4\|UniProtKB=G1KD71	Anolis carolinensis	O
XENLA\|Gene=myog.S\|UniProtKB=Q8UUX7	Xenopus laevis	O
XENLA\|Gene=myog.L\|UniProtKB=Q8UUX8	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-490105\|UniProtKB=Q0IIX1	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000015906.2\|UniProtKB=H2MMH0	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-980526-265\|UniProtKB=Q9DG26	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000010722.1\|UniProtKB=W5MXM9	lepisosteus oculatus	O
HUMAN\|HGNC=7611\|UniProtKB=P15172	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000003406.4\|UniProtKB=H2Q385	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000008222.3\|UniProtKB=G3S3Y5	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000006400.4\|UniProtKB=F7GWN8	Macaca mulatta	O
MOUSE\|MGI=MGI=97275\|UniProtKB=P10085	Mus musculus	O
RAT\|RGD=631429\|UniProtKB=Q02346	Rattus norvegicus	O
BOVIN\|Gene=MYOD1\|UniProtKB=Q7YS82	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000002216.4\|UniProtKB=Q0VBX9	Bos taurus	O
PIG\|Gene=MYOD1\|UniProtKB=P49811	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000013375.5\|UniProtKB=F1S9A9	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000002132.3\|UniProtKB=F6W511	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000004973.5\|UniProtKB=M3W380	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845014938.1\|UniProtKB=A0A8I3NJT4	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000006749.3\|UniProtKB=F7CCS4	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000047737.1\|UniProtKB=A0A6I8PJY8	Ornithorhynchus anatinus	O
CHICK\|Gene=MYOD1\|UniProtKB=P16075	Gallus gallus	O
CHICK\|Ensembl=ENSGALG00010024369.1\|UniProtKB=F1NHM3	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000039537.1\|UniProtKB=A0A803U034	Anolis carolinensis	O
XENLA\|Gene=myod1-a\|UniProtKB=P13904	Xenopus laevis	O
XENLA\|Gene=myod1-b\|UniProtKB=P16076	Xenopus laevis	O
XENLA\|Gene=myod1.L\|UniProtKB=Q6GN48	Xenopus laevis	O
XENLA\|Gene=myod1.S\|UniProtKB=Q8AVZ0	Xenopus laevis	O
XENTR\|Xenbase=XB-GENE-1017498\|UniProtKB=Q7T109	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000022079.1\|UniProtKB=A0A3B3HQE2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000000694.2\|UniProtKB=A0A3B3IPA5	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-980526-561\|UniProtKB=Q90477	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000002164.1\|UniProtKB=W5M2B6	lepisosteus oculatus	O
CIOIN\|Ensembl=ENSCING00000007328.2\|UniProtKB=F6YKF5	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_261622\|UniProtKB=C3YG29	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_119486\|UniProtKB=C3YG26	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_276983\|UniProtKB=Q7Z1G3	Branchiostoma floridae	O
BRAFL\|Gene=LOC118406791\|UniProtKB=A0A9J7KK94	Branchiostoma floridae	O
BRAFL\|Gene=LOC118407176\|UniProtKB=A0A9J7HPS8	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC105442066\|UniProtKB=A0A7M7LT89	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115918205\|UniProtKB=A0A7M7NZL3	Strongylocentrotus purpuratus	LDO
CAEBR\|Gene_ORFName=CBG13470\|UniProtKB=Q17295	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0002922\|UniProtKB=P22816	Drosophila melanogaster	LDO
TRICA\|EnsemblGenome=TC015855\|UniProtKB=D2A4B5	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW009440\|UniProtKB=B7PYE2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG181683\|UniProtKB=T1FH84	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG188369\|UniProtKB=T1FPX5	helobdella robusta	LDO