PANTHER Gene Information

Gene Symbol(s):

smc-3

Organism:

Caenorhabditis elegans

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Gene Name:

Structural maintenance of chromosomes protein 3

Gene ID:

WBGene00004873

Protein ID:

B2FDA8

Persistent Id:

PTN000434567

Alternate Ids:

SMC3_CAEEL(UniProtKB-ID)	817033906(GI)
NM_001136370(refSeq)	I2HAB3(AltAccession)
CAQ48406(EMBL-CDS)	WBGene00004873(Ensembl)
SMC3(Synonym)	BX284603(EMBL)
Y47D3A.26a(WormBase_TRS)	smc-3{ECO:0000312\|WormBase:Y47D3A.26b}(Symbol)
WBGene00004873(WormBase)	CE41472(WormBase_PRO)
176559(GeneID)
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PANTHER Classification

PANTHER Family:	STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 (PTHR43977)
PANTHER Subfamily:	STRUCTURAL MAINTENANCE OF CHROMOSOMES PROTEIN 3 (PTHR43977:SF1)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	ATP hydrolysis activity, ATP binding, double-stranded DNA binding
GO BP Complete:	cell division, DNA repair, chromosome organization, mitotic sister chromatid cohesion, DNA damage response, cell cycle
GO CC Complete:	nucleus, cohesin complex, protein-containing complex, chromosome, mitotic cohesin complex, chromatin

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Mitotic Prometaphase, Cell Cycle, SUMOylation of DNA damage response and repair proteins, Cell Cycle, Mitotic, M Phase, SUMOylation, Cohesin Loading onto Chromatin, Mitotic Telophase/Cytokinesis, Establishment of Sister Chromatid Cohesion, Resolution of Sister Chromatid Cohesion, S Phase, SUMO E3 ligases SUMOylate target proteins, Post-translational protein modification, Metabolism of proteins

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2468\|UniProtKB=Q9UQE7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000002939.5\|UniProtKB=H2R1R2	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000023979.2\|UniProtKB=G3RP17	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000007982.4\|UniProtKB=F7HNK4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1339795\|UniProtKB=Q9CW03	Mus musculus	LDO
RAT\|RGD=62006\|UniProtKB=P97690	Rattus norvegicus	LDO
BOVIN\|Gene=SMC3\|UniProtKB=O97594	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000013905.6\|UniProtKB=A7Z065	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000010625.5\|UniProtKB=A0A8W4FFA1	Sus scrofa	O
PIG\|Ensembl=ENSSSCG00000010625.5\|UniProtKB=A0A8W4FFA1	Sus scrofa	LDO
FELCA\|Ensembl=ENSFCAG00000010557.6\|UniProtKB=M3WDH5	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000010463.4\|UniProtKB=F7BL05	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000001596.4\|UniProtKB=A0A6I8NIQ2	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010018388.1\|UniProtKB=A0A8V0ZD52	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000015557.4\|UniProtKB=G1KRH8	Anolis carolinensis	LDO
XENLA\|Gene=smc3.S\|UniProtKB=A0A8J0TBE1	Xenopus laevis	O
XENLA\|Gene=smc3\|UniProtKB=O93309	Xenopus laevis	O
XENLA\|Gene=smc3.L\|UniProtKB=Q8AW91	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-957583\|UniProtKB=A0A6I8QIV1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015257.2\|UniProtKB=A0A3B3HL13	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-3196\|UniProtKB=Q803N2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000012326.1\|UniProtKB=W5N3G9	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000003687.4\|UniProtKB=F6WUJ1	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118414893\|UniProtKB=A0A9J7L2S4	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC594026\|UniProtKB=A0A7M7NV40	Strongylocentrotus purpuratus	LDO
CAEBR\|Gene_ORFName=CBG13206\|UniProtKB=A8XHA7	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00107491\|UniProtKB=A0A2A6C9D1	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0015615\|UniProtKB=Q9VXE9	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP008672\|UniProtKB=A0A1S4GYX0	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP006388\|UniProtKB=Q8I952	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC011028\|UniProtKB=D6X4W0	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_63318\|UniProtKB=E9HJ58	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG157320\|UniProtKB=T1EM97	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g50013\|UniProtKB=A7SQ80	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG64300\|UniProtKB=B3S903	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_8368\|UniProtKB=A9UZV5	Monosiga brevicollis	LDO
YEAST\|SGD=S000003610\|UniProtKB=P47037	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AAL182W\|UniProtKB=Q75FB3	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000193720\|UniProtKB=A0A1D8PJK7	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_A00616g\|UniProtKB=Q6CI88	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_06364\|UniProtKB=Q00737	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_2G14080\|UniProtKB=Q4X0B2	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU07554\|UniProtKB=Q7S024	Neurospora crassa	LDO
SCLS1\|Gene_ORFName=SS1G_06422\|UniProtKB=A7EM75	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_03248\|UniProtKB=Q0UYB6	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC10F6.09c\|UniProtKB=O42649	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_05019\|UniProtKB=B6K8E1	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CND02930\|UniProtKB=Q5KIH7	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_04389\|UniProtKB=A0A0D1DSI0	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_17512\|UniProtKB=E3L531	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_88502\|UniProtKB=F4P2U0	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=EHI_164820\|UniProtKB=C4M1X5	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0276101\|UniProtKB=Q552D9	Dictyostelium discoideum	LDO
LEIMA\|EnsemblGenome=LMJF_08_0010\|UniProtKB=Q4QIG8	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb927.5.3510\|UniProtKB=Q57UB5	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_137745\|UniProtKB=A8B2I5	Giardia intestinalis	LDO
TRIV3\|Gene_ORFName=TVAG_193240\|UniProtKB=A2DH38	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_333960\|UniProtKB=A2EIA2	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_340870\|UniProtKB=A2DTP6	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_0414000\|UniProtKB=Q8I1U7	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00028847001\|UniProtKB=A0BGZ5	Paramecium tetraurelia	LDO
PHYRM\|Gene=H3HC97_PHYRM\|UniProtKB=H3HC97	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_10g445650v5\|UniProtKB=A0A2K3DAV3	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00029p00198810\|UniProtKB=W1PPC1	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_70G00200\|UniProtKB=A0A0K9NQG4	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma02_g16150\|UniProtKB=A0A804I3E5	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_020986mg\|UniProtKB=K3Z368	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3009G251500\|UniProtKB=A0A1B6PAK6	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb297550\|UniProtKB=A0A1D6MEC8	Zea mays	LDO
BRADI\|EnsemblGenome=BRADI_1g17900v3\|UniProtKB=A0A0Q3GUT3	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0195960\|UniProtKB=A0A8I7B841	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2A02G457500\|UniProtKB=A0A3B6B656	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2B02G479900\|UniProtKB=A0A3B6CCU8	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G458200\|UniProtKB=A0A3B6DJH5	Triticum aestivum	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.1HG0093570\|UniProtKB=A0A8I7B1R8	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS1B02G463400\|UniProtKB=A0A3B5Z6P9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1A02G428700\|UniProtKB=A0A3B5Y757	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS1D02G438000\|UniProtKB=A0A3B6A213	Triticum aestivum	LDO
NELNU\|Gene_ORFName=HUJ06_028525\|UniProtKB=A0A1U7ZYL4	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110803365\|UniProtKB=A0A9R0JAP6	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr06g0271731\|UniProtKB=A0A251UJ55	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600321750\|UniProtKB=A0A9R1X928	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C200060370\|UniProtKB=A0A9R1XVG2	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C300156100\|UniProtKB=A0A9R1VYY4	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C200060290\|UniProtKB=A0A9R1WCU4	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a021237mg\|UniProtKB=A0A022R8F2	Erythranthe guttata	O
ERYGU\|Gene_ORFName=MIMGU_mgv1a000343mg\|UniProtKB=A0A022R6A6	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_18033\|UniProtKB=A0A2G2ZDK3	Capsicum annuum	LDO
CAPAN\|EnsemblGenome=T459_34994\|UniProtKB=A0A2G2XUH4	Capsicum annuum	LDO
SOLLC\|EnsemblGenome=Solyc06g073780.3\|UniProtKB=A0A3Q7GZH8	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107765531\|UniProtKB=A0A1S3XJ23	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_04s0069g00890\|UniProtKB=F6H9I4	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_J00601\|UniProtKB=A0A059AB83	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=GSBRNA2T00039466001\|UniProtKB=A0A078JF49	Brassica napus	O
BRACM\|EnsemblGenome=Bra000522\|UniProtKB=M4C8J4	Brassica campestris	O
BRANA\|Gene_ORFName=GSBRNA2T00022266001\|UniProtKB=A0A078J4K6	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra034328\|UniProtKB=M4EZT5	Brassica campestris	LDO
ARATH\|TAIR=locus=2045159\|UniProtKB=Q56YN8	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107902776\|UniProtKB=A0A1U8J6Z5	Gossypium hirsutum	O
GOSHI\|Gene=LOC107959237\|UniProtKB=A0A1U8PHN8	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_041166\|UniProtKB=A0A061GUR7	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g0013282mg\|UniProtKB=A0A067DQI6	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_009G155200v3\|UniProtKB=A0A2K1Z8F1	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_06G005500\|UniProtKB=A0A2C9VNR3	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0573510\|UniProtKB=B9SUJ2	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_02G271900\|UniProtKB=I1JIN1	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_14G044900\|UniProtKB=I1M7D7	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_1g051825\|UniProtKB=A0A072VIT6	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr14_15200\|UniProtKB=A0A2I4H6Q7	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_4G279900\|UniProtKB=A0A0A0L0E5	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_6G149900\|UniProtKB=A0A251NQQ8	Prunus persica	LDO
PHYPA\|EnsemblGenome=Pp3c24_13420\|UniProtKB=A0A2K1IGN8	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0048s0100\|UniProtKB=A0A2R6WYQ7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_006720020\|UniProtKB=A0A1Y1IPG9	Klebsormidium nitens	LDO
METJA\|EnsemblGenome=MJ_1643\|UniProtKB=Q59037	Methanocaldococcus jannaschii	LDO