PANTHER Gene Information

Gene Symbol(s):

rga-8

Organism:

Caenorhabditis elegans

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Gene Name:

Rho-GAP domain-containing protein

Gene ID:

WBGene00021324

Protein ID:

A0A2K5AU23

Persistent Id:

PTN000364807

Alternate Ids:

BX284606(EMBL)	CE52457(WormBase_PRO)
WBGene00021324(Ensembl)	A0A2K5AU23_CAEEL(UniProtKB-ID)
SPC48682(EMBL-CDS)	WBGene00021324(WormBase)
Y34B4A.8c(WormBase_TRS)	A0A2K5AU23(Synonym)
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PANTHER Classification

PANTHER Family:	3BP-1 RELATED RHOGAP (PTHR14130)
PANTHER Subfamily:	RHO GTPASE-ACTIVATING PROTEIN 92B (PTHR14130:SF14)
PANTHER GO-slim Molecular Function:	GTPase activator activity
PANTHER GO-slim Biological Process:	regulation of small GTPase mediated signal transduction regulation of actin cytoskeleton organization
PANTHER GO-slim Cellular Component:	intracellular anatomical structure
PANTHER protein class:	GTPase-activating protein

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	GTPase activator activity
GO BP Complete:	regulation of actin cytoskeleton organization, signal transduction, regulation of Rac protein signal transduction, positive regulation of GTPase activity
GO CC Complete:	intracellular anatomical structure

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

RHOA GTPase cycle, Signal Transduction, Signaling by Rho GTPases, Miro GTPases and RHOBTB3, RAC2 GTPase cycle, Signaling by Rho GTPases, RHOD GTPase cycle, RHOQ GTPase cycle, RHO GTPase cycle, RAC3 GTPase cycle, CDC42 GTPase cycle, RAC1 GTPase cycle

Orthologs

ID	Organism	Type
HUMAN\|HGNC=29096\|UniProtKB=Q17R89	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000008787.6\|UniProtKB=A0A2I3SMH6	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000015831.3\|UniProtKB=A0A2I2ZFN0	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000022515.4\|UniProtKB=F6YNY2	Macaca mulatta	O
MOUSE\|MGI=MGI=2144423\|UniProtKB=Q5SSM3	Mus musculus	O
RAT\|RGD=1305664\|UniProtKB=F1LQX4	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000021938.5\|UniProtKB=F1MFA5	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000018019.5\|UniProtKB=A0A5G2R4C3	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000025167.4\|UniProtKB=A0A3Q2HA68	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000008402.6\|UniProtKB=A0A5F5XFK4	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845003750.1\|UniProtKB=A0A8I3MRN8	Canis lupus familiaris	O
MONDO\|Ensembl=ENSMODG00000008107.4\|UniProtKB=A0A5F8HLE6	Monodelphis domestica	O
ORNAN\|Ensembl=ENSOANG00000050303.1\|UniProtKB=A0A6I8PD85	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010029930.1\|UniProtKB=A0A3Q2TYW2	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000017636.3\|UniProtKB=A0A803TWX3	Anolis carolinensis	O
XENLA\|Gene=arhgap44.L\|UniProtKB=A0A8J1LSB7	Xenopus laevis	O
XENLA\|Gene=arhgap44.S\|UniProtKB=A0A8J1LYA3	Xenopus laevis	O
XENTR\|Gene=arhgap44\|UniProtKB=A0A8J1IXC5	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000012549.2\|UniProtKB=H2MAZ8	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000007345.2\|UniProtKB=A0A3B3IH89	Oryzias latipes	O
DANRE\|Gene=arhgap44\|UniProtKB=A0A8M9QN52	Danio rerio	O
DANRE\|Gene=si=ch211-114m9.1\|UniProtKB=A0A8M9Q151	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000013174.1\|UniProtKB=W5N6H5	lepisosteus oculatus	O
HUMAN\|Gene=BARGIN\|UniProtKB=Q6ZT62	Homo sapiens	O
HUMAN\|HGNC=10824\|UniProtKB=Q9Y3L3	Homo sapiens	O
PANTR\|Ensembl=ENSPTRG00000014340.7\|UniProtKB=H2R2A0	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000011833.3\|UniProtKB=G3R852	Gorilla gorilla gorilla	O
MACMU\|Ensembl=ENSMMUG00000003854.4\|UniProtKB=F7HAB0	Macaca mulatta	O
MOUSE\|MGI=MGI=104603\|UniProtKB=P55194	Mus musculus	O
RAT\|RGD=1306275\|UniProtKB=D3ZFJ3	Rattus norvegicus	O
BOVIN\|Ensembl=ENSBTAG00000030257.4\|UniProtKB=E1BL56	Bos taurus	O
PIG\|Ensembl=ENSSSCG00000028531.4\|UniProtKB=A0A8W4FNZ4	Sus scrofa	O
HORSE\|Ensembl=ENSECAG00000007864.4\|UniProtKB=F6T530	Equus caballus	O
FELCA\|Ensembl=ENSFCAG00000018984.5\|UniProtKB=M3WPG5	Felis catus	O
CANLF\|Ensembl=ENSCAFG00845005964.1\|UniProtKB=A0A8I3NCX7	Canis lupus familiaris	O
ORNAN\|Ensembl=ENSOANG00000011219.4\|UniProtKB=A0A6I8PFN8	Ornithorhynchus anatinus	O
CHICK\|Ensembl=ENSGALG00010014026.1\|UniProtKB=A0A8V0YMG6	Gallus gallus	O
ANOCA\|Ensembl=ENSACAG00000015666.4\|UniProtKB=G1KRF9	Anolis carolinensis	O
XENLA\|Gene=sh3bp1.L\|UniProtKB=A0A1L8GP19	Xenopus laevis	O
XENLA\|Gene=sh3bp1.S\|UniProtKB=A0A8J1KLI5	Xenopus laevis	O
XENTR\|Ensembl=ENSXETG00000032660\|UniProtKB=A0A6I8SWA3	Xenopus tropicalis	O
ORYLA\|Ensembl=ENSORLG00000029676.1\|UniProtKB=A0A3B3IA92	Oryzias latipes	O
DANRE\|ZFIN=ZDB-GENE-121128-2\|UniProtKB=E7FFF8	Danio rerio	O
LEPOC\|Ensembl=ENSLOCG00000011670.1\|UniProtKB=W5N133	lepisosteus oculatus	O
HUMAN\|HGNC=18239\|UniProtKB=Q68EM7	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007900.5\|UniProtKB=H2QAT1	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000003654.3\|UniProtKB=G3QM70	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000029176.3\|UniProtKB=A0A1D5Q9C2	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1917747\|UniProtKB=Q3UIA2	Mus musculus	LDO
RAT\|RGD=628767\|UniProtKB=Q99N37	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000020043.5\|UniProtKB=A0A3Q1LLI7	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000031488.3\|UniProtKB=A0A286ZZA8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000017234.4\|UniProtKB=A0A3Q2HXB8	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000019231.5\|UniProtKB=A0A337SP03	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845000580.1\|UniProtKB=A0A8I3RP97	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000016300.5\|UniProtKB=A0A5F8GKY0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000001468.4\|UniProtKB=A0A6I8NCJ4	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010018276.1\|UniProtKB=A0A8V0Z535	Gallus gallus	LDO
XENLA\|Gene=arhgap17.L\|UniProtKB=A0A1L8EYF7	Xenopus laevis	O
XENLA\|Gene=arhgap17.S\|UniProtKB=A0A8J1LZC1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-981776\|UniProtKB=A0A8J0QLW0	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000009090.2\|UniProtKB=H2LZ36	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000028308.1\|UniProtKB=A0A3B3HH39	Oryzias latipes	LDO
DANRE\|Gene=arhgap17b\|UniProtKB=A0A8M3AXW1	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-050417-56\|UniProtKB=F1R7M1	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000005365.1\|UniProtKB=W5MDL6	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118428373\|UniProtKB=A0A9J7M5C5	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC592564\|UniProtKB=A0A7M7NQT0	Strongylocentrotus purpuratus	LDO
CAEBR\|WormBase=WBGene00035078\|UniProtKB=A8XKD4	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00110064\|UniProtKB=A0A2A6D253	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0038747\|UniProtKB=Q9VDS5	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP009727\|UniProtKB=A0A1S4H2S3	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC003222\|UniProtKB=D6WE39	Tribolium castaneum	LDO
IXOSC\|EnsemblGenome=ISCW003282\|UniProtKB=B7PAK9	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG164475\|UniProtKB=T1EVH0	helobdella robusta	O
HELRO\|EnsemblGenome=HelroG190227\|UniProtKB=T1FRS7	helobdella robusta	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_26508\|UniProtKB=A9V2K3	Monosiga brevicollis	LDO
USTMA\|EnsemblGenome=UMAG_01161\|UniProtKB=A0A0D1E6N8	Ustilago maydis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_25160\|UniProtKB=F4P2Y4	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0283955\|UniProtKB=Q54QB9	Dictyostelium discoideum	LDO