PANTHER Gene Information

Gene Symbol(s):

prdx-6

Organism:

Caenorhabditis elegans

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Gene Name:

Thioredoxin domain-containing protein

Gene ID:

WBGene00021401

Protein ID:

Q8MXT1

Persistent Id:

PTN000073838

Alternate Ids:

CCD70254(EMBL-CDS)	WBGene00021401(WormBase)
Y38C1AA(WormBase_TRS)	Q8MXT1(Synonym)
WBGene00021401(Ensembl)	NM_171241(refSeq)
CE31640(WormBase_PRO)	373219820(GI)
176837(GeneID)	BX284604(EMBL)
Q8MXT1_CAEEL(UniProtKB-ID)
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PANTHER Classification

PANTHER Family:	MCG48959-RELATED (PTHR43503)
PANTHER Subfamily:	PEROXIREDOXIN-6 (PTHR43503:SF4)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:	cellular homeostasis
PANTHER GO-slim Cellular Component:	cytosol
PANTHER protein class:	peroxidase

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	peroxidase activity, antioxidant activity, oxidoreductase activity, peroxiredoxin activity
GO BP Complete:	cell redox homeostasis
GO CC Complete:	cytosol

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Cellular responses to stress, Neutrophil degranulation, Cellular response to chemical stress, Innate Immune System, Immune System, Detoxification of Reactive Oxygen Species, Cellular responses to stimuli

Orthologs

ID	Organism	Type
PANTR\|Ensembl=ENSPTRG00000046673.1\|UniProtKB=A0A2I3TVB3	Pan troglodytes	O
GORGO\|Ensembl=ENSGGOG00000043347.1\|UniProtKB=A0A2I2Z726	Gorilla gorilla gorilla	O
HUMAN\|HGNC=16753\|UniProtKB=P30041	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000042455.2\|UniProtKB=H2RFX7	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000026357.2\|UniProtKB=G3S6S1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000008776.3\|UniProtKB=F7F6H0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1336888\|UniProtKB=Q8BG37	Mus musculus	O
MOUSE\|MGI=MGI=894320\|UniProtKB=O08709	Mus musculus	LDO
RAT\|RGD=150344534\|UniProtKB=A0A8I6ASU0	Rattus norvegicus	O
RAT\|RGD=71005\|UniProtKB=O35244	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000031464.3\|UniProtKB=A0A3Q1LKU1	Bos taurus	O
BOVIN\|Ensembl=ENSBTAG00000004855\|UniProtKB=O77834	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000022742\|UniProtKB=Q9TSX9	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022468.4\|UniProtKB=F7AXI9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000039648.3\|UniProtKB=A0A2I2UL25	Felis catus	LDO
CANLF\|Ensembl=ENSCAFG00845012128.1\|UniProtKB=A0A8I3NWQ3	Canis lupus familiaris	LDO
MONDO\|Ensembl=ENSMODG00000004032.3\|UniProtKB=F7CMG3	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000000916.4\|UniProtKB=F6RBB7	Ornithorhynchus anatinus	LDO
CHICK\|Gene_ORFName=RCJMB04_18k11\|UniProtKB=Q5ZJF4	Gallus gallus	LDO
CHICK\|Ensembl=ENSGALG00010013528.1\|UniProtKB=A0A8V0YL25	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000042284.1\|UniProtKB=A0A803TBB8	Anolis carolinensis	LDO
XENLA\|Gene=prdx6.S\|UniProtKB=Q7SYQ4	Xenopus laevis	LDO
XENLA\|Gene=prdx6.L\|UniProtKB=Q7SYT1	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-951731\|UniProtKB=Q6P624	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000010012.2\|UniProtKB=H2M2C2	Oryzias latipes	O
ORYLA\|Ensembl=ENSORLG00000014530.2\|UniProtKB=H2MHU2	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-040426-1778\|UniProtKB=Q6PBK9	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000010332.1\|UniProtKB=W5MW99	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000009606.3\|UniProtKB=F7ADF2	Ciona intestinalis	O
CIOIN\|Ensembl=ENSCING00000023965.1\|UniProtKB=H2XQS5	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118431162\|UniProtKB=A0A9J7MBT1	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421068\|UniProtKB=A0A9J7MXX0	Branchiostoma floridae	O
BRAFL\|Gene=LOC118421035\|UniProtKB=A0A9J7LJQ3	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC579284\|UniProtKB=A0A7M7PKS1	Strongylocentrotus purpuratus	LDO
PRIPA\|EnsemblGenome=WBGene00276903\|UniProtKB=A0A454XSR6	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0033521\|UniProtKB=A1Z893	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0033520\|UniProtKB=A1Z892	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0033518\|UniProtKB=Q7JX87	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP011824\|UniProtKB=Q7PZB4	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC004948\|UniProtKB=D6WCX5	Tribolium castaneum	O
DROME\|FlyBase=FBgn0031479\|UniProtKB=Q9VQI7	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP007020\|UniProtKB=Q7QIQ4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC013791\|UniProtKB=D6WJ53	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_231855\|UniProtKB=E9HSC7	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG185631\|UniProtKB=T1FN25	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g234225\|UniProtKB=A7RMT9	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG49888\|UniProtKB=B3RP43	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_32821\|UniProtKB=A9V1X1	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_17605\|UniProtKB=A9USG5	Monosiga brevicollis	LDO
YEAST\|SGD=S000000934\|UniProtKB=P32634	Saccharomyces cerevisiae	O
YEAST\|SGD=S000003165\|UniProtKB=P53094	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AFR168W\|UniProtKB=Q754A4	Eremothecium gossypii	O
CANAL\|CGD=CAL0000193099\|UniProtKB=Q5ADT1	Candida albicans	O
EMENI\|EnsemblGenome=ANIA_10227\|UniProtKB=C8VNU2	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_4G08570\|UniProtKB=Q4WPA2	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU06030\|UniProtKB=V5ILG5	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_04703\|UniProtKB=A7EHB1	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_00784\|UniProtKB=Q0V5D0	Phaeosphaeria nodorum	O
SCHPO\|PomBase=SPBC21.05c\|UniProtKB=P15258	Schizosaccharomyces pombe	O
SCHJY\|EnsemblGenome=SJAG_03623\|UniProtKB=B6K4R1	Schizosaccharomyces japonicus	O
CRYNJ\|EnsemblGenome=CNA07370\|UniProtKB=Q5KN84	Cryptococcus neoformans	O
USTMA\|EnsemblGenome=UMAG_00884\|UniProtKB=A0A0D1E5N7	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_17203\|UniProtKB=E3L306	Puccinia graminis	O
YEAST\|SGD=S000000160\|UniProtKB=P34227	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AGR368W\|UniProtKB=Q74Z38	Eremothecium gossypii	O
YARLI\|EnsemblGenome=YALI0_F08195g\|UniProtKB=Q6C2G0	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_03973\|UniProtKB=Q5B657	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_8G07130\|UniProtKB=Q4WBR1	Neosartorya fumigata	O
SCLS1\|EnsemblGenome=SS1G_02121\|UniProtKB=A7E9Z1	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_02785\|UniProtKB=Q0UZM9	Phaeosphaeria nodorum	O
EREGS\|EnsemblGenome=AGOS_ACL197W\|UniProtKB=Q75CW3	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000196398\|UniProtKB=Q5A5A0	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_A19426g\|UniProtKB=Q6CGH1	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_10223\|UniProtKB=C8VNU1	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G15070\|UniProtKB=Q4WWB4	Neosartorya fumigata	O
ASPFU\|EnsemblGenome=AFUA_4G08580\|UniProtKB=Q4WPA3	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU06031\|UniProtKB=Q7S4F4	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_04704\|UniProtKB=A7EHB2	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_00787\|UniProtKB=Q0V5C7	Phaeosphaeria nodorum	LDO
CRYNJ\|EnsemblGenome=CNK00130\|UniProtKB=Q5K9Z8	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_06404\|UniProtKB=A0A0D1DMG0	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_17942\|UniProtKB=E3L5U0	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_21125\|UniProtKB=F4PFM4	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0282517\|UniProtKB=Q54SE2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_79639\|UniProtKB=F0ZN68	Dictyostelium purpureum	LDO
PLAF7\|EnsemblGenome=PF3D7_0802200\|UniProtKB=Q8IAM2	Plasmodium falciparum	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_18089\|UniProtKB=B8C6N8	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3HBZ0_PHYRM\|UniProtKB=H3HBZ0	Phytophthora ramorum	O
PHYRM\|Gene=H3G8P5_PHYRM\|UniProtKB=H3G8P5	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_16g654250v5\|UniProtKB=A0A2K3CT23	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00045p00055840\|UniProtKB=W1P216	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_44G00080\|UniProtKB=A0A0K9P0X1	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_44G00090\|UniProtKB=A0A0K9P330	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma11_g19280\|UniProtKB=A0A804L9J0	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_031051mg\|UniProtKB=K3ZWR9	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G391100\|UniProtKB=C5X3B9	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb328770\|UniProtKB=B4FYU6	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os07g0638400\|UniProtKB=P0C5D1	Oryza sativa	O
ORYSJ\|EnsemblGenome=Os07g0638300\|UniProtKB=P0C5C9	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_1g20040v3\|UniProtKB=I1GRW3	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0120840\|UniProtKB=A0A8I6WHE5	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS2B02G174400\|UniProtKB=Q6W8Q2	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2D02G154300\|UniProtKB=D0PRB4	Triticum aestivum	LDO
NELNU\|Gene=LOC104611250\|UniProtKB=A0A1U8B6F0	Nelumbo nucifera	O
NELNU\|Gene_ORFName=HUJ06_009041\|UniProtKB=A0A144ZK66	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110779424\|UniProtKB=A0A9R0JMD6	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr07g0287031\|UniProtKB=A0A251UB30	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C600325420\|UniProtKB=A0A9R1X7E7	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a022281mg\|UniProtKB=A0A022QI62	Erythranthe guttata	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a013521mg\|UniProtKB=A0A022QZL4	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_28703\|UniProtKB=A0A2G2YHJ2	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400027720\|UniProtKB=M1CNG8	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc03g096040.3\|UniProtKB=A0A3Q7FPK3	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107810138\|UniProtKB=A0A1S4BNA1	Nicotiana tabacum	LDO
TOBAC\|Gene=LOC107823604\|UniProtKB=A0A1S4CXA1	Nicotiana tabacum	LDO
VITVI\|Gene_OrderedLocusName=VIT_05s0077g00050\|UniProtKB=F6H6W9	Vitis vinifera	O
VITVI\|EnsemblGenome=Vitvi05g00235\|UniProtKB=D7T674	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_G02036\|UniProtKB=A0A059BFG8	Eucalyptus grandis	LDO
BRACM\|EnsemblGenome=Bra038102\|UniProtKB=M4FAI8	Brassica campestris	LDO
BRACM\|EnsemblGenome=Bra032241\|UniProtKB=M4ETV9	Brassica campestris	LDO
ARATH\|TAIR=locus=2023772\|UniProtKB=O04005	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107896588\|UniProtKB=A0A1U8ILL6	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107916248\|UniProtKB=A0A1U8KEE0	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_021465\|UniProtKB=A0A061EP93	Theobroma cacao	LDO
POPTR\|Gene_ORFName=POPTR_008G099900\|UniProtKB=A0A3N7FDS0	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_03G210400\|UniProtKB=A0A2C9W9K8	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_15G003600\|UniProtKB=A0A2C9UBV7	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1002870\|UniProtKB=B9RZX8	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_05G133500\|UniProtKB=A0A0R0K508	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_08G088000\|UniProtKB=I1KRJ7	Glycine max	O
MEDTR\|EnsemblGenome=MTR_4g094720\|UniProtKB=A0A072UP31	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr07_12430\|UniProtKB=A0A2I4FQD8	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G171050\|UniProtKB=A0A0A0L979	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G109000\|UniProtKB=M5XU54	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_164163\|UniProtKB=D8QMW3	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c22_8470\|UniProtKB=A9RJ06	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0057s0102\|UniProtKB=A0A2R6WUH5	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_001090295\|UniProtKB=A0A1Y1HX80	Klebsormidium nitens	LDO
RICCO\|Gene_ORFName=RCOM_1916960\|UniProtKB=B9TDU3	Ricinus communis	O
SELML\|EnsemblGenome=SELMODRAFT_148807\|UniProtKB=D8RPL5	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_181036\|UniProtKB=D8SMC0	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c10_21340\|UniProtKB=A9RWK3	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c20_21100\|UniProtKB=A9S0X9	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0042s0090\|UniProtKB=A0A2R6X1S3	Marchantia polymorpha	O
KLENI\|Gene_ORFName=KFL_000640110\|UniProtKB=A0A1Y1HQE0	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_000640150\|UniProtKB=A0A1Y1HUJ7	Klebsormidium nitens	O
KLENI\|Gene_ORFName=KFL_008060010\|UniProtKB=A0A1Y1IL02	Klebsormidium nitens	O
SACS2\|EnsemblGenome=SSO2121\|UniProtKB=P95895	Sulfolobus solfataricus	LDO
PYRAE\|EnsemblGenome=PAE2085\|UniProtKB=Q8ZVW7	Pyrobaculum aerophilum	LDO
METAC\|EnsemblGenome=MA_4103\|UniProtKB=Q8TIP2	Methanosarcina acetivorans	LDO
METJA\|EnsemblGenome=MJ_0736\|UniProtKB=Q58146	Methanocaldococcus jannaschii	LDO
THEKO\|EnsemblGenome=TK0537\|UniProtKB=Q5JF30	Thermococcus kodakaraensis	LDO
THEMA\|EnsemblGenome=TM_0807\|UniProtKB=Q9WZR4	Thermotoga maritima	LDO
GLOVI\|Gene=Q7NIM8_GLOVI\|UniProtKB=Q7NIM8	Gloeobacter violaceus	LDO
SYNY3\|Gene=P73348_SYNY3\|UniProtKB=P73348	Synechocystis	LDO
AQUAE\|EnsemblGenome=aq_858\|UniProtKB=O67024	Aquifex aeolicus	LDO
THEYD\|EnsemblGenome=THEYE_A1053\|UniProtKB=B5YKW6	Thermodesulfovibrio yellowstonii	LDO
DICTD\|EnsemblGenome=Dtur_0572\|UniProtKB=B8DZC8	Dictyoglomus turgidum	LDO
BRADU\|Gene=Q89JH5_BRADU\|UniProtKB=Q89JH5	Bradyrhizobium diazoefficiens	LDO
PSEAE\|EnsemblGenome=PA3450\|UniProtKB=Q9HYF6	Pseudomonas aeruginosa	LDO