PANTHER Gene Information   
Gene Symbol(s): MMP2
Organism: Canis lupus familiaris
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Gene Name: Matrix metallopeptidase 2
Gene ID: ENSCAFG00845000865.1
Protein ID: A0A8I3MGS0
Persistent Id: PTN000024243
Alternate Ids:
ENSCAFT00845001478(Ensembl_TRS) A0A8I3MGS0(Synonym)
ENSCAFP00845001159(Ensembl_PRO) ENSCAFG00845000865(Ensembl)
A0A8I3MGS0_CANLF(UniProtKB-ID)
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PANTHER Classification
PANTHER Family: MATRIX METALLOPROTEINASE (PTHR10201)
PANTHER Subfamily: 72 KDA TYPE IV COLLAGENASE (PTHR10201:SF29)  
PANTHER GO-slim Molecular Function: metalloendopeptidase activity
PANTHER GO-slim Biological Process: response to hypoxia
tissue remodeling
catabolic process
extracellular matrix organization
PANTHER GO-slim Cellular Component: extracellular space
PANTHER protein class: metalloprotease
Pathway Categories: Alzheimer disease-presenilin pathway
   Matrix metalloprotease

GO MF Complete: zinc ion binding, metalloendopeptidase activity
GO BP Complete: response to amyloid-beta, bone trabecula formation, embryo implantation, face morphogenesis, tissue remodeling, cellular response to amino acid stimulus, response to hypoxia, cellular response to UV-A, positive regulation of vascular associated smooth muscle cell proliferation, blood vessel maturation, proteolysis, intramembranous ossification, extracellular matrix organization, endodermal cell differentiation, collagen catabolic process, cell migration, cellular response to reactive oxygen species
GO CC Complete: extracellular space, extracellular matrix, plasma membrane, sarcomere
Reactome Pathways: Extra-nuclear estrogen signaling, ESR-mediated signaling, Axon guidance, Nervous system development, Extracellular matrix organization, EPH-ephrin mediated repulsion of cells, EPH-Ephrin signaling, Degradation of the extracellular matrix, Signaling by Nuclear Receptors, Signal Transduction, Collagen degradation, Developmental Biology, Activation of Matrix Metalloproteinases