PANTHER Gene Information   
Gene Symbol(s): FGF18
Organism: Canis lupus familiaris
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Gene Name: Uncharacterized protein
Gene ID: ENSCAFG00845001658.1
Protein ID: A0A8I3MIK8
Persistent Id: PTN000160205
Alternate Ids:
A0A8I3MIK8_CANLF(UniProtKB-ID) A0A8I3MIK8(Synonym)
ENSCAFG00845001658(Ensembl) ENSCAFP00845002406(Ensembl_PRO)
ENSCAFT00845003015(Ensembl_TRS)
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PANTHER Classification
PANTHER Family: FIBROBLAST GROWTH FACTOR (PTHR11486)
PANTHER Subfamily: FIBROBLAST GROWTH FACTOR 18 (PTHR11486:SF4)  
PANTHER GO-slim Molecular Function: growth factor activity
fibroblast growth factor receptor binding
PANTHER GO-slim Biological Process: regulation of cell migration
fibroblast growth factor receptor signaling pathway
positive regulation of protein phosphorylation
cell differentiation
positive regulation of MAPK cascade
positive regulation of gene expression
positive regulation of cell population proliferation
animal organ morphogenesis
PANTHER GO-slim Cellular Component: extracellular space
cytoplasm
PANTHER protein class: growth factor
Pathway Categories: FGF signaling pathway
   fibroblast growth factor
GENE ONTOLOGY DATABASE ANNOTATIONS      Click to Expand...
GO MF Complete: growth factor activity, type 2 fibroblast growth factor receptor binding, type 1 fibroblast growth factor receptor binding
GO BP Complete: positive regulation of cell population proliferation, fibroblast growth factor receptor signaling pathway, neurogenesis, positive regulation of MAPK cascade, regulation of cell migration
GO CC Complete: extracellular space, cytoplasm
REACTOME DATABASE ANNOTATIONS   Click to Expand...
Reactome Pathways: Signaling by FGFR3, PI3K Cascade, PI-3K cascade:FGFR4, Phospholipase C-mediated cascade; FGFR4, FGFRL1 modulation of FGFR1 signaling, Signaling by FGFR4, Phospholipase C-mediated cascade; FGFR3, FRS-mediated FGFR2 signaling, IRS-related events triggered by IGF1R, Insulin receptor signalling cascade, Signaling by Insulin receptor, FGFR3b ligand binding and activation, IGF1R signaling cascade, Phospholipase C-mediated cascade; FGFR2, RAF/MAP kinase cascade, Signaling by FGFR, Signaling by Receptor Tyrosine Kinases, FGFR3c ligand binding and activation, FGFR2c ligand binding and activation, Negative regulation of FGFR2 signaling, FRS-mediated FGFR3 signaling, MAPK1/MAPK3 signaling, SHC-mediated cascade:FGFR3, IRS-mediated signalling, FGFR3 ligand binding and activation, Downstream signaling of activated FGFR3, PI-3K cascade:FGFR2, Downstream signaling of activated FGFR2, FRS-mediated FGFR4 signaling, Negative regulation of FGFR3 signaling, PI-3K cascade:FGFR3, SHC-mediated cascade:FGFR2, Negative regulation of FGFR4 signaling, PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, FGFR4 ligand binding and activation, Signal Transduction, PIP3 activates AKT signaling, FGFR2 ligand binding and activation, Intracellular signaling by second messengers, Signaling by FGFR2, Downstream signaling of activated FGFR4, Signaling by FGFR1, Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R), Negative regulation of the PI3K/AKT network, SHC-mediated cascade:FGFR4, MAPK family signaling cascades

Orthologs