PANTHER Gene Information

Gene Symbol(s):

PPP4C

Organism:

Canis lupus familiaris

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Gene Name:

Serine_threonine-protein phosphatase

Gene ID:

ENSCAFG00845001731.1

Protein ID:

A0A8I3MJ81

Persistent Id:

PTN000185465

Alternate Ids:

A0A8I3MJ81(Synonym)	A0A8I3MJ81_CANLF(UniProtKB-ID)
489947(GeneID)	ENSCAFP00845002428(Ensembl_PRO)
57088343(GI)	XP_547067(refSeq)
ENSCAFT00845003041(Ensembl_TRS)	ENSCAFG00845001731(Ensembl)
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PANTHER Classification

PANTHER Family:	SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A-RELATED (PTHR45619)
PANTHER Subfamily:	SERINE_THREONINE-PROTEIN PHOSPHATASE 4 CATALYTIC SUBUNIT (PTHR45619:SF8)
PANTHER GO-slim Molecular Function:	protein serine/threonine phosphatase activity
PANTHER GO-slim Biological Process:	double-strand break repair via homologous recombination
PANTHER GO-slim Cellular Component:	cytoplasm nucleus
PANTHER protein class:	protein phosphatase

Pathway Categories:

EGF receptor signaling pathway

protein phosphatase 2A

FGF signaling pathway

protein phosphatase 2A

GENE ONTOLOGY DATABASE ANNOTATIONS

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GO MF Complete:	protein serine/threonine phosphatase activity
GO BP Complete:	double-strand break repair via homologous recombination, regulation of double-strand break repair via homologous recombination
GO CC Complete:	nucleus, cytoplasm, cytosol, chromatin, protein phosphatase 4 complex, plasma membrane, nucleoplasm

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA), Homology Directed Repair, Processing of DNA double-strand break ends, DNA Double-Strand Break Repair, DNA Repair

Orthologs

ID	Organism	Type
HUMAN\|HGNC=9319\|UniProtKB=P60510	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000007984.5\|UniProtKB=H2RA87	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000008634.3\|UniProtKB=G3QZX1	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000982.4\|UniProtKB=F6SRT0	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1891763\|UniProtKB=P97470	Mus musculus	LDO
RAT\|RGD=621225\|UniProtKB=Q5BJ92	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000012928\|UniProtKB=A6H772	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000036817.3\|UniProtKB=M3VK32	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000022179.4\|UniProtKB=F6X854	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000014171.5\|UniProtKB=M3WK76	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000015692.4\|UniProtKB=F7E0S5	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000008136.2\|UniProtKB=A0A6I8NML7	Ornithorhynchus anatinus	LDO
ANOCA\|Ensembl=ENSACAG00000014977.4\|UniProtKB=H9GLS6	Anolis carolinensis	LDO
XENLA\|Gene=ppp4c\|UniProtKB=Q6IP91	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-970535\|UniProtKB=Q6P861	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000017341.2\|UniProtKB=H2MSF1	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-4433\|UniProtKB=A8WGP3	Danio rerio	O
DANRE\|ZFIN=ZDB-GENE-080219-32\|UniProtKB=A9JRC7	Danio rerio	LDO
CIOIN\|Ensembl=ENSCING00000004907.3\|UniProtKB=F7B991	Ciona intestinalis	LDO
BRAFL\|Gene=LOC118425624\|UniProtKB=A0A9J7LXX9	Branchiostoma floridae	O
BRAFL\|Gene_ORFName=BRAFLDRAFT_264576\|UniProtKB=C3YD79	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC594644\|UniProtKB=A0A7M7RGS0	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00004086\|UniProtKB=Q9XTT8	Caenorhabditis elegans	O
CAEEL\|WormBase=WBGene00004085\|UniProtKB=Q9XW79	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00032850\|UniProtKB=A8XE00	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00275840\|UniProtKB=A0A2A6BBV9	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0036212\|UniProtKB=Q95TV5	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0023177\|UniProtKB=O76932	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP003779\|UniProtKB=Q7QFY4	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC015726\|UniProtKB=D2A3N9	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_209708\|UniProtKB=E9G8K4	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW015013\|UniProtKB=B7QHS1	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG186046\|UniProtKB=T1FNL3	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g177129\|UniProtKB=A7RFC7	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG64151\|UniProtKB=B3S495	Trichoplax adhaerens	LDO
MONBE\|EnsemblGenome=MONBRDRAFT_35497\|UniProtKB=A9UPH0	Monosiga brevicollis	O
MONBE\|EnsemblGenome=MONBRDRAFT_17180\|UniProtKB=A9UPZ9	Monosiga brevicollis	LDO
YEAST\|SGD=S000002482\|UniProtKB=P32345	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AGR136W\|UniProtKB=Q74ZR2	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000195388\|UniProtKB=A0A1D8PSJ8	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_F10505g\|UniProtKB=Q6C264	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_00103\|UniProtKB=C8VQM3	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G12010\|UniProtKB=Q4WVG4	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU08301\|UniProtKB=Q7RVY0	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_08420\|UniProtKB=A7ESW5	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_13986\|UniProtKB=Q0U2W5	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPBC26H8.05c\|UniProtKB=O74789	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_00823\|UniProtKB=B6JWP5	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA03970\|UniProtKB=Q5KP72	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_10235\|UniProtKB=A0A0D1CEC5	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_17157\|UniProtKB=E3L425	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_89142\|UniProtKB=F4P493	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_031240\|UniProtKB=C4M4K6	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=EHI_151480\|UniProtKB=C4LSJ0	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_010290\|UniProtKB=C4LYS6	Entamoeba histolytica	O
ENTH1\|EnsemblGenome=CL6EHI_147720\|UniProtKB=C4M907	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0272116\|UniProtKB=Q9Y0B7	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_76474\|UniProtKB=F0ZDQ6	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_28_2670\|UniProtKB=Q4Q7Z5	Leishmania major	O
TRYB2\|Gene_ORFName=Tb11.01.3770\|UniProtKB=Q382Y7	Trypanosoma brucei	O
LEIMA\|EnsemblGenome=LMJF_32_3040\|UniProtKB=Q4Q4W8	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb11.01.8740\|UniProtKB=Q380Z0	Trypanosoma brucei	LDO
GIAIC\|EnsemblGenome=GL50803_14311\|UniProtKB=A8BLT6	Giardia intestinalis	O
GIAIC\|EnsemblGenome=GL50803_15215\|UniProtKB=A8B748	Giardia intestinalis	LDO
GIAIC\|EnsemblGenome=GL50803_15214\|UniProtKB=A8B747	Giardia intestinalis	O
GIAIC\|Gene_ORFName=GL50803_0013524\|UniProtKB=A0A644F932	Giardia intestinalis	O
GIAIC\|EnsemblGenome=GL50803_2053\|UniProtKB=A8BYQ2	Giardia intestinalis	O
TRIV3\|Gene_ORFName=TVAG_269330\|UniProtKB=A2EG46	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_174680\|UniProtKB=A2EK15	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_451050\|UniProtKB=A2EYQ8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_125660\|UniProtKB=A2ET73	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_033860\|UniProtKB=A2DGL9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_265400\|UniProtKB=A2FGA5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_298190\|UniProtKB=A2ET12	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_016570\|UniProtKB=A2EQZ5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_192950\|UniProtKB=A2DH09	Trichomonas vaginalis	LDO
TRIV3\|Gene_ORFName=TVAG_474090\|UniProtKB=A2EQ55	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_212030\|UniProtKB=A2EIF9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_409160\|UniProtKB=A2G2Q6	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_292980\|UniProtKB=A2EWY8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_050440\|UniProtKB=A2EJH1	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_093230\|UniProtKB=A2DBE6	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_071580\|UniProtKB=A2D861	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_381110\|UniProtKB=A2G1G7	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_156940\|UniProtKB=A2FM31	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_310000\|UniProtKB=A2EKR6	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_008650\|UniProtKB=A2F7T9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_132160\|UniProtKB=A2FNJ9	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_445420\|UniProtKB=A2E4K8	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_191270\|UniProtKB=A2EFL0	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_284570\|UniProtKB=A2ENB5	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_341240\|UniProtKB=A2DTT3	Trichomonas vaginalis	O
TRIV3\|Gene_ORFName=TVAG_459440\|UniProtKB=A2FHK4	Trichomonas vaginalis	O
PLAF7\|EnsemblGenome=PF3D7_0927700\|UniProtKB=Q8I2N2	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00034086001\|UniProtKB=A0C1E3	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017217001\|UniProtKB=A0DIJ3	Paramecium tetraurelia	O
PARTE\|Gene_ORFName=GSPATT00019262001\|UniProtKB=P49576	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00034087001\|UniProtKB=A0C1E4	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00037233001\|UniProtKB=A0CCD1	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00035044001\|UniProtKB=A0C447	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00017464001\|UniProtKB=A0DJ90	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00037234001\|UniProtKB=A0CCD2	Paramecium tetraurelia	LDO
THAPS\|EnsemblGenome=THAPSDRAFT_26473\|UniProtKB=B8CFV6	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3HDB5_PHYRM\|UniProtKB=H3HDB5	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_12g494900v5\|UniProtKB=A8JDN1	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00090p00130390\|UniProtKB=W1NVM1	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_112G00190\|UniProtKB=A0A0K9Q590	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma01_g00080\|UniProtKB=A0A804HNK8	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma07_g06340\|UniProtKB=A0A804JST9	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_030389mg\|UniProtKB=K3ZUV8	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G157300\|UniProtKB=C5X8B4	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb094420\|UniProtKB=A0A804ML01	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os09g0284200\|UniProtKB=Q6EPR6	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g27240v3\|UniProtKB=I1IP37	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0471330\|UniProtKB=F2DC57	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5B02G173100\|UniProtKB=A0A3B6LJA8	Triticum aestivum	LDO
NELNU\|Gene=LOC104606541\|UniProtKB=A0A1U8AUF0	Nelumbo nucifera	O
NELNU\|Gene=LOC104594154\|UniProtKB=A0A1U7ZUH9	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110791286\|UniProtKB=A0A9R0IMF1	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr08g0350991\|UniProtKB=A0A251U7T7	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr13g0594221\|UniProtKB=A0A251SU32	Helianthus annuus	O
HELAN\|EnsemblGenome=HanXRQr2_Chr05g0234091\|UniProtKB=A0A251UUT0	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C500229690\|UniProtKB=A0A9R1X957	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a010682mg\|UniProtKB=A0A022R153	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_20853\|UniProtKB=A0A1U8HJH5	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400022201\|UniProtKB=M1C0I5	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc07g065020.3\|UniProtKB=A0A3Q7HI40	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107814008\|UniProtKB=A0A1S4C0Y4	Nicotiana tabacum	O
TOBAC\|Gene=LOC107819862\|UniProtKB=A0A1S4CKR8	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi19g00577\|UniProtKB=D7T847	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_F03506\|UniProtKB=A0A059BVV2	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_A03P56880.1\|UniProtKB=A0A078IBS8	Brassica napus	O
BRACM\|EnsemblGenome=Bra019089\|UniProtKB=M4DRE6	Brassica campestris	O
ARATH\|TAIR=locus=2116402\|UniProtKB=P48529	Arabidopsis thaliana	O
ARATH\|TAIR=locus=2161700\|UniProtKB=P48528	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107903479\|UniProtKB=A0A1U8J3Y4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107932709\|UniProtKB=A0A1U8M0F4	Gossypium hirsutum	O
GOSHI\|Gene=LOC107919537\|UniProtKB=A0A1U8KPV8	Gossypium hirsutum	O
GOSHI\|Gene=LOC107895216\|UniProtKB=A0A1U8ICP7	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_030784\|UniProtKB=A0A061F4I3	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_001G358700v3\|UniProtKB=B9GJG4	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_011G092200v3\|UniProtKB=B9I197	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_03G135800\|UniProtKB=A0A2C9W764	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0546920\|UniProtKB=B9SYY8	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_02G295600\|UniProtKB=I1JJE9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_14G017800\|UniProtKB=I1M6L3	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_5g093990\|UniProtKB=G7K499	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr09_15800\|UniProtKB=A0A2I4EZA1	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G083210\|UniProtKB=A0A0A0K505	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_4G224600\|UniProtKB=M5WHX1	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_100159\|UniProtKB=D8RS50	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c8_17660\|UniProtKB=A9TE32	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c24_5950\|UniProtKB=A0A2K1IFP8	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0042s0011\|UniProtKB=A0A2R6X1G7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_004150070\|UniProtKB=A0A1Y1ICG9	Klebsormidium nitens	LDO