PANTHER Gene Information

Gene Symbol(s):

METTL18

Organism:

Canis lupus familiaris

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Tree

Gene Name:

Methyltransferase like 18

Gene ID:

ENSCAFG00845002040.1

Protein ID:

A0A8I3MKK7

Persistent Id:

PTN000473417

Alternate Ids:

ENSCAFT00845003554(Ensembl_TRS)	A0A8I3MKK7(Synonym)
XP_005622603(refSeq)	A0A8I3MKK7_CANLF(UniProtKB-ID)
100685478(GeneID)	345803269(GI)
ENSCAFG00845002040(Ensembl)	ENSCAFP00845002822(Ensembl_PRO)
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PANTHER Classification

PANTHER Family:	HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN (PTHR14614)
PANTHER Subfamily:	HISTIDINE PROTEIN METHYLTRANSFERASE 1 HOMOLOG (PTHR14614:SF39)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	protein modifying enzyme

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	heat shock protein binding, protein-L-histidine N-tele-methyltransferase activity
GO BP Complete:	regulation of translation, regulation of translational elongation, regulation of ribosome biogenesis, regulation of rRNA processing, methylation
GO CC Complete:	nucleus, cytosol, protein-containing complex, nucleolus

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Orthologs

ID	Organism	Type
HUMAN\|HGNC=28793\|UniProtKB=O95568	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000001663.3\|UniProtKB=H2Q0K6	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000015904.3\|UniProtKB=G3RIK4	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000016581.4\|UniProtKB=F7CK58	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1917212\|UniProtKB=Q9CZ09	Mus musculus	LDO
RAT\|RGD=1306783\|UniProtKB=Q4KM84	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000021671.4\|UniProtKB=A0A452DJ31	Bos taurus	LDO
BOVIN\|Gene=METTL18\|UniProtKB=Q2KIJ2	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000006285.5\|UniProtKB=F1RSC8	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000006141.3\|UniProtKB=F6Z9E9	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000008151.5\|UniProtKB=A0A5F5Y870	Felis catus	LDO
MONDO\|Ensembl=ENSMODG00000003390.2\|UniProtKB=F6TCE0	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000016063.2\|UniProtKB=A0A6I8PNU3	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010014298.1\|UniProtKB=A0A8V0YH60	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000040367.1\|UniProtKB=A0A803T424	Anolis carolinensis	LDO
XENLA\|Gene=mettl18.S\|UniProtKB=A0A1L8H989	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-5811219\|UniProtKB=F6VVQ4	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000026116.1\|UniProtKB=A0A3B3IF64	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-090313-192\|UniProtKB=B8A4F2	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000018228.1\|UniProtKB=W5NNX0	lepisosteus oculatus	LDO
BRAFL\|Gene=LOC118426546\|UniProtKB=A0A9J7M0L7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC115926142\|UniProtKB=A0A7M7P6F9	Strongylocentrotus purpuratus	LDO
STRPU\|EnsemblGenome=LOC100891488\|UniProtKB=A0A7M7N627	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00010450\|UniProtKB=Q21069	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00031383\|UniProtKB=A8X9U9	Caenorhabditis briggsae	LDO
DROME\|FlyBase=FBgn0031494\|UniProtKB=Q9VQK8	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP009532\|UniProtKB=Q7QG71	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC030563\|UniProtKB=A0A139WBZ2	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_207481\|UniProtKB=E9FYX8	Daphnia pulex	LDO
HELRO\|EnsemblGenome=HelroG90686\|UniProtKB=T1G7U5	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g126398\|UniProtKB=A7SPU2	Nematostella vectensis	LDO
YEAST\|SGD=S000001372\|UniProtKB=P40481	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_ADL242W\|UniProtKB=Q75B19	Eremothecium gossypii	LDO
YARLI\|EnsemblGenome=YALI0_F05258g\|UniProtKB=Q6C2T7	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_01445\|UniProtKB=Q5BDD5	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_8G04330\|UniProtKB=Q4WCI2	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU00956\|UniProtKB=Q7SGG6	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_01694\|UniProtKB=A7E8R6	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_14205\|UniProtKB=Q0U231	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC1071.05\|UniProtKB=Q9UTQ8	Schizosaccharomyces pombe	LDO
CRYNJ\|EnsemblGenome=CNA06680\|UniProtKB=Q5KNF3	Cryptococcus neoformans	LDO
USTMA\|EnsemblGenome=UMAG_02979\|UniProtKB=A0A0D1E389	Ustilago maydis	LDO
PUCGT\|EnsemblGenome=PGTG_12504\|UniProtKB=E3KUV7	Puccinia graminis	LDO
PUCGT\|EnsemblGenome=PGTG_07528\|UniProtKB=E3KDB6	Puccinia graminis	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_86828\|UniProtKB=F4NYV7	Batrachochytrium dendrobatidis	LDO
ENTH1\|EnsemblGenome=CL6EHI_152400\|UniProtKB=C4LSS7	Entamoeba histolytica	LDO
DICDI\|dictyBase=DDB_G0270580\|UniProtKB=Q55DL2	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_89318\|UniProtKB=F0ZV32	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_15_0730\|UniProtKB=Q4QFB2	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb09.160.4920\|UniProtKB=Q38ER5	Trypanosoma brucei	LDO
TRIV3\|Gene_ORFName=TVAG_490140\|UniProtKB=A2FB51	Trichomonas vaginalis	LDO
PLAF7\|EnsemblGenome=PF3D7_1022100\|UniProtKB=C6S3D3	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00031935001\|UniProtKB=A0BT36	Paramecium tetraurelia	LDO
PHYRM\|Gene=H3GWE3_PHYRM\|UniProtKB=H3GWE3	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_08g378250v5\|UniProtKB=A0A2K3DHU7	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00066p00080930\|UniProtKB=U5DFB7	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_36G00560\|UniProtKB=A0A0K9P604	Zostera marina	O
ZOSMR\|Gene_ORFName=ZOSMA_72G00180\|UniProtKB=A0A0K9NQ09	Zostera marina	O
MUSAM\|EnsemblGenome=Ma09_g20740\|UniProtKB=A0A804KLV4	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma09_g02260\|UniProtKB=A0A804KF20	Musa acuminata subsp. malaccensis	O
MUSAM\|EnsemblGenome=Ma05_g17830\|UniProtKB=A0A804J5N4	Musa acuminata subsp. malaccensis	O
SETIT\|EnsemblGenome=SETIT_030344mg\|UniProtKB=K3ZUR3	Setaria italica	O
BRADI\|EnsemblGenome=BRADI_4g35110v3\|UniProtKB=I1IRT3	Brachypodium distachyon	O
WHEAT\|EnsemblGenome=TraesCS5D02G305300\|UniProtKB=A0A3B6MUL9	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS5B02G297800\|UniProtKB=A0A3B6LQ19	Triticum aestivum	O
SETIT\|EnsemblGenome=SETIT_010492mg\|UniProtKB=K3Y8F4	Setaria italica	O
SORBI\|EnsemblGenome=SORBI_3006G131400\|UniProtKB=C5YBE0	Sorghum bicolor	O
MAIZE\|EnsemblGenome=Zm00001eb425580\|UniProtKB=C0HDY0	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb078810\|UniProtKB=C0PFW2	Zea mays	O
ORYSJ\|EnsemblGenome=Os04g0492400\|UniProtKB=Q7X8M4	Oryza sativa	O
BRADI\|EnsemblGenome=BRADI_5g14320v3\|UniProtKB=I1IZ66	Brachypodium distachyon	O
HORVV\|EnsemblGenome=HORVU.MOREX.r3.2HG0177740\|UniProtKB=A0A8I6XF63	Hordeum vulgare subsp. vulgare	O
WHEAT\|EnsemblGenome=TraesCS2B02G367700\|UniProtKB=W5BQU7	Triticum aestivum	O
WHEAT\|EnsemblGenome=TraesCS2A02G349300\|UniProtKB=A0A3B6B0I5	Triticum aestivum	O
NELNU\|Gene=LOC104587022\|UniProtKB=A0A1U7Z728	Nelumbo nucifera	O
SPIOL\|Gene=LOC110789098\|UniProtKB=A0A9R0JWS4	Spinacia oleracea	O
HELAN\|EnsemblGenome=HanXRQr2_Chr07g0279241\|UniProtKB=A0A251UAJ4	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C600320200\|UniProtKB=A0A9R1V3W9	Lactuca sativa	O
HELAN\|EnsemblGenome=HanXRQr2_Chr11g0507311\|UniProtKB=A0A251UT97	Helianthus annuus	O
LACSA\|Gene_ORFName=LSAT_V11C100027900\|UniProtKB=A0A9R1WNX7	Lactuca sativa	O
CAPAN\|EnsemblGenome=T459_17983\|UniProtKB=A0A1U8HAA9	Capsicum annuum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400026907\|UniProtKB=M1CK10	Solanum tuberosum	O
SOLLC\|EnsemblGenome=Solyc06g073380.3\|UniProtKB=A0A3Q7HVJ2	Solanum lycopersicum	O
TOBAC\|Gene=LOC107798307\|UniProtKB=A0A1S4AJH4	Nicotiana tabacum	O
TOBAC\|Gene=LOC107814427\|UniProtKB=A0A1S4C2F5	Nicotiana tabacum	O
VITVI\|EnsemblGenome=Vitvi05g01480\|UniProtKB=D7U1N3	Vitis vinifera	O
EUCGR\|EnsemblGenome=EUGRSUZ_A00073\|UniProtKB=A0A059DB99	Eucalyptus grandis	O
BRANA\|Gene_ORFName=DARMORV10_C03P28810.1\|UniProtKB=A0A078I4Y7	Brassica napus	O
BRANA\|EnsemblGenome=GSBRNA2T00093992001\|UniProtKB=A0A078JU53	Brassica napus	O
BRACM\|EnsemblGenome=Bra000300\|UniProtKB=M4C7X2	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C04P70350.1\|UniProtKB=A0A078GFG0	Brassica napus	O
BRANA\|Gene_ORFName=DARMORV10_A04P32660.1\|UniProtKB=A0A078GY20	Brassica napus	O
BRACM\|EnsemblGenome=Bra037720\|UniProtKB=M4F9F7	Brassica campestris	O
ARATH\|TAIR=locus=2041076\|UniProtKB=O22847	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107903782\|UniProtKB=A0A1U8J544	Gossypium hirsutum	O
GOSHI\|Gene=LOC107927321\|UniProtKB=A0A1U8LK99	Gossypium hirsutum	O
GOSHI\|Gene=LOC107914704\|UniProtKB=A0A1U8KE29	Gossypium hirsutum	O
GOSHI\|Gene=LOC107940494\|UniProtKB=A0A1U8MRF0	Gossypium hirsutum	O
THECC\|EnsemblGenome=TCM_020118\|UniProtKB=A0A061EJY9	Theobroma cacao	O
CITSI\|Gene_ORFName=CISIN_1g018716mg\|UniProtKB=A0A067DKR9	Citrus sinensis	O
POPTR\|EnsemblGenome=POPTR_017G031700v3\|UniProtKB=U5FL77	Populus trichocarpa	O
POPTR\|EnsemblGenome=POPTR_007G127300v3\|UniProtKB=A0A2K1ZTG6	Populus trichocarpa	O
MANES\|EnsemblGenome=MANES_11G119500\|UniProtKB=A0A2C9V0P0	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_04G042200\|UniProtKB=A0A251LG96	Manihot esculenta	O
RICCO\|Gene_ORFName=RCOM_0143500\|UniProtKB=B9T795	Ricinus communis	O
SOYBN\|EnsemblGenome=GLYMA_13G343500\|UniProtKB=I1M546	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_15G030800\|UniProtKB=A0A0R0FW09	Glycine max	O
MEDTR\|EnsemblGenome=MTR_2g098630\|UniProtKB=G7IHS1	Medicago truncatula	O
JUGRE\|EnsemblGenome=Jr12_07850\|UniProtKB=A0A2I4ET69	Juglans regia	O
JUGRE\|EnsemblGenome=Jr07_17130\|UniProtKB=A0A2I4DH12	Juglans regia	O
CUCSA\|EnsemblGenome=Csa_4G015130\|UniProtKB=A0A0A0KXE5	Cucumis sativus	O
PRUPE\|EnsemblGenome=PRUPE_1G190500\|UniProtKB=A0A251QZL1	Prunus persica	O
AMBTC\|EnsemblGenome=AMTR_s00003p00162530\|UniProtKB=W1P5N3	Amborella trichopoda	LDO
ZOSMR\|Gene_ORFName=ZOSMA_122G00300\|UniProtKB=A0A0K9Q2P5	Zostera marina	LDO
MUSAM\|EnsemblGenome=Ma03_g27660\|UniProtKB=A0A804IH06	Musa acuminata subsp. malaccensis	LDO
SETIT\|EnsemblGenome=SETIT_032052mg\|UniProtKB=K3ZZL8	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3002G179100\|UniProtKB=A0A1B6QC28	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb098490\|UniProtKB=C0PEP9	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os09g0359900\|UniProtKB=Q6K562	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_4g28580v3\|UniProtKB=A0A0Q3H9F2	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.5HG0474920\|UniProtKB=A0A8I6YG97	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS5B02G187500\|UniProtKB=A0A3B6LLI6	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS5D02G195100\|UniProtKB=A0A3B6MQV7	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS5A02G195900\|UniProtKB=A0A3B6KIN7	Triticum aestivum	LDO
NELNU\|Gene=LOC104598287\|UniProtKB=A0A1U7ZXP3	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110776404\|UniProtKB=A0A9R0HVK1	Spinacia oleracea	LDO
HELAN\|EnsemblGenome=HanXRQr2_Chr15g0704641\|UniProtKB=A0A251SBP7	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C200066910\|UniProtKB=A0A9R1XVL4	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a010754mg\|UniProtKB=A0A022QYQ4	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_31290\|UniProtKB=A0A2G2YAT4	Capsicum annuum	LDO
SOLTU\|EnsemblGenome=PGSC0003DMG400004663\|UniProtKB=M1A0C0	Solanum tuberosum	LDO
TOBAC\|Gene=LOC107783878\|UniProtKB=A0A1S3Z7M2	Nicotiana tabacum	O
TOBAC\|Gene=LOC107806927\|UniProtKB=A0A1S4BCX4	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi05g01252\|UniProtKB=F6I4C0	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_H00019\|UniProtKB=A0A059ATW8	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C04P41810.1\|UniProtKB=A0A078FEC8	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra032753\|UniProtKB=M4EVC0	Brassica campestris	LDO
ARATH\|TAIR=locus=2129286\|UniProtKB=Q8VY62	Arabidopsis thaliana	LDO
GOSHI\|Gene=LOC107915423\|UniProtKB=A0A1U8KC64	Gossypium hirsutum	O
GOSHI\|Gene=LOC107915101\|UniProtKB=A0A1U8KB58	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_020216\|UniProtKB=A0A061ES46	Theobroma cacao	LDO
POPTR\|EnsemblGenome=POPTR_001G321100v3\|UniProtKB=B9GFI8	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_05G201800\|UniProtKB=A0A2C9VY18	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_0369990\|UniProtKB=B9T2Q0	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_18G002700\|UniProtKB=I1MYA8	Glycine max	LDO
SOYBN\|EnsemblGenome=GLYMA_11G254400\|UniProtKB=K7LRX8	Glycine max	O
MEDTR\|EnsemblGenome=MTR_7g008030\|UniProtKB=I3S9D2	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr12_08790\|UniProtKB=A0A2I4GXB1	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_3G171830\|UniProtKB=A0A0A0LAX3	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_1G166800\|UniProtKB=A0A251QYS4	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_84048\|UniProtKB=D8R427	Selaginella moellendorffii	LDO
SELML\|EnsemblGenome=SELMODRAFT_73463\|UniProtKB=D8QPB2	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_180720\|UniProtKB=D8SL63	Selaginella moellendorffii	O
PHYPA\|EnsemblGenome=Pp3c8_15830\|UniProtKB=A0A7I4EGT9	Physcomitrella patens	O
PHYPA\|EnsemblGenome=Pp3c20_16690\|UniProtKB=A0A2K1IVH5	Physcomitrella patens	LDO
MARPO\|EnsemblGenome=MARPO_0002s0255\|UniProtKB=A0A2R6XUK7	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_007390030\|UniProtKB=A0A1Y1INW3	Klebsormidium nitens	LDO