PANTHER Gene Information

Gene Symbol(s):

TMPRSS6

Organism:

Canis lupus familiaris

View Gene in Tree

Tree

Gene Name:

Transmembrane serine protease 6

Gene ID:

ENSCAFG00845007611.1

Protein ID:

A0A8I3RU13

Persistent Id:

PTN000666269

Alternate Ids:

ENSCAFP00845010413(Ensembl_PRO)	608593(GeneID)
XP_850550(refSeq)	345777094(GI)
ENSCAFG00845007611(Ensembl)	A0A8I3RU13(Synonym)
ENSCAFT00845013420(Ensembl_TRS)	A0A8I3RU13_CANLF(UniProtKB-ID)
Show All

PANTHER Classification

PANTHER Family:	TRANSMEMBRANE PROTEASE SERINE (PTHR24253)
PANTHER Subfamily:	TRANSMEMBRANE PROTEASE SERINE 6 (PTHR24253:SF62)
PANTHER GO-slim Molecular Function:
PANTHER GO-slim Biological Process:
PANTHER GO-slim Cellular Component:
PANTHER protein class:	serine protease

Pathway Categories:

No pathway information available

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	serine-type endopeptidase activity
GO BP Complete:	negative regulation of transcription by RNA polymerase II, intracellular iron ion homeostasis, negative regulation of BMP signaling pathway, self proteolysis, multicellular organismal-level iron ion homeostasis, BMP signaling pathway, membrane protein proteolysis, positive regulation of transcription by RNA polymerase II
GO CC Complete:	extracellular space, plasma membrane

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Collagen degradation, Extracellular matrix organization, Degradation of the extracellular matrix

Orthologs

ID	Organism	Type
HUMAN\|HGNC=16517\|UniProtKB=Q8IU80	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000014327.5\|UniProtKB=H2QLL5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000034825.2\|UniProtKB=G3SKP5	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000000151.4\|UniProtKB=F7HM00	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1919003\|UniProtKB=Q9DBI0	Mus musculus	LDO
RAT\|RGD=1307138\|UniProtKB=A0A8I6G6J0	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000032152.3\|UniProtKB=F1MWW8	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000026067.4\|UniProtKB=I3LLB2	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000011051.4\|UniProtKB=A0A9L0R4Q5	Equus caballus	LDO
MONDO\|Ensembl=ENSMODG00000000693.4\|UniProtKB=A0A5F8G910	Monodelphis domestica	LDO
ORNAN\|Ensembl=ENSOANG00000013614.4\|UniProtKB=A0A6I8NWI8	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010014778.1\|UniProtKB=A0A8V0YPR8	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000016119.4\|UniProtKB=G1KS78	Anolis carolinensis	LDO
XENLA\|Gene=LOC108703853\|UniProtKB=A0A8J1LWE0	Xenopus laevis	LDO
XENTR\|Ensembl=ENSXETG00000036456\|UniProtKB=A0A803JMF5	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000010701.2\|UniProtKB=H2M4P3	Oryzias latipes	LDO
LEPOC\|Ensembl=ENSLOCG00000011175.1\|UniProtKB=W5MZC1	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000008363.3\|UniProtKB=F7AJY7	Ciona intestinalis	O
STRPU\|EnsemblGenome=LOC589018\|UniProtKB=A0A7M7NUN0	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC100889227\|UniProtKB=A0A7M7P9S2	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC115922975\|UniProtKB=A0A7M7NPP3	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC763539\|UniProtKB=A0A7M7PB37	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC586328\|UniProtKB=A0A7M7NT17	Strongylocentrotus purpuratus	O
STRPU\|EnsemblGenome=LOC763150\|UniProtKB=A0A7M7LIP2	Strongylocentrotus purpuratus	O
PRIPA\|EnsemblGenome=WBGene00092395\|UniProtKB=A0A2A6B9E2	Pristionchus pacificus	O
DROME\|FlyBase=FBgn0265011\|UniProtKB=A1Z7M3	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008996\|UniProtKB=A0A1S4GZU9	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC033855\|UniProtKB=A0A139WFG0	Tribolium castaneum	O
DROME\|FlyBase=FBgn0003319\|UniProtKB=Q05319	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP002784\|UniProtKB=Q7QCS5	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC002659\|UniProtKB=D6WEQ0	Tribolium castaneum	O
DROME\|FlyBase=FBgn0033362\|UniProtKB=A8DY75	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP008997\|UniProtKB=A0A1S4GZV2	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC030609\|UniProtKB=D6WT55	Tribolium castaneum	O
IXOSC\|EnsemblGenome=ISCW010211\|UniProtKB=B7Q228	Ixodes scapularis	O
ANOGA\|EnsemblGenome=AGAP002422\|UniProtKB=Q7QC30	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_305928\|UniProtKB=E9GTT8	Daphnia pulex	O
ANOGA\|EnsemblGenome=AGAP008183\|UniProtKB=A0A1S4GXI4	Anopheles gambiae	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_107786\|UniProtKB=E9GY87	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_26576\|UniProtKB=E9GY88	Daphnia pulex	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_323225\|UniProtKB=E9GY90	Daphnia pulex	O
DROME\|FlyBase=FBgn0035663\|UniProtKB=Q9VRS5	Drosophila melanogaster	O
ANOGA\|EnsemblGenome=AGAP001395\|UniProtKB=A0A1S4GCF6	Anopheles gambiae	O
ANOGA\|EnsemblGenome=AGAP004569\|UniProtKB=A0A1S4GLG0	Anopheles gambiae	O
TRICA\|EnsemblGenome=TC003081\|UniProtKB=D6WFM2	Tribolium castaneum	O
DAPPU\|EnsemblGenome=DAPPUDRAFT_304051\|UniProtKB=E9GJI2	Daphnia pulex	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g198217\|UniProtKB=A7RJY0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g127465\|UniProtKB=A7SQF1	Nematostella vectensis	O
NEMVE\|Gene_ORFName=NEMVEDRAFT_v1g111870\|UniProtKB=A7SB63	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g130234\|UniProtKB=A7SSR9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109826\|UniProtKB=A7S9G1	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g230861\|UniProtKB=A7SSS0	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g41116\|UniProtKB=A7SZI9	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g109239\|UniProtKB=A7S8Y5	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g88458\|UniProtKB=A7RP61	Nematostella vectensis	O
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g124644\|UniProtKB=A7SNB8	Nematostella vectensis	O
TRIAD\|EnsemblGenome=TriadG61839\|UniProtKB=B3SC39	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG25686\|UniProtKB=B3RY71	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG53235\|UniProtKB=B3RNP0	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG18710\|UniProtKB=B3RIF5	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG5625\|UniProtKB=B3RYJ8	Trichoplax adhaerens	O
TRIAD\|EnsemblGenome=TriadG26286\|UniProtKB=B3RZF9	Trichoplax adhaerens	O