PANTHER Gene Information

Gene Symbol(s):

Organism:

Canis lupus familiaris

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Tree

Gene Name:

Citrate synthase

Gene ID:

ENSCAFG00845007644.1

Protein ID:

A0A8I3N6V8

Persistent Id:

PTN000201246

Alternate Ids:

A0A8I3N6V8_CANLF(UniProtKB-ID)	A0A8I3N6V8(Synonym)
ENSCAFG00845007644(Ensembl)	ENSCAFP00845010628(Ensembl_PRO)
ENSCAFT00845013692(Ensembl_TRS)
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PANTHER Classification

PANTHER Family:	CITRATE SYNTHASE (PTHR11739)
PANTHER Subfamily:	CITRATE SYNTHASE, MITOCHONDRIAL (PTHR11739:SF8)
PANTHER GO-slim Molecular Function:	acyltransferase activity
PANTHER GO-slim Biological Process:	carbohydrate metabolic process tricarboxylic acid cycle
PANTHER GO-slim Cellular Component:	mitochondrial matrix
PANTHER protein class:	transferase

Pathway Categories:

Pyruvate metabolism

Citrate Synthetase

TCA cycle

Citrate Synthase

GENE ONTOLOGY DATABASE ANNOTATIONS

Click to Expand...

GO MF Complete:	citrate (Si)-synthase activity
GO BP Complete:	carbohydrate metabolic process, citrate metabolic process, tricarboxylic acid cycle
GO CC Complete:	mitochondrial matrix

REACTOME DATABASE ANNOTATIONS Click to Expand...

Reactome Pathways:

Citric acid cycle (TCA cycle), Metabolism of proteins, Pyruvate metabolism and Citric Acid (TCA) cycle, The citric acid (TCA) cycle and respiratory electron transport, Metabolism, Mitochondrial protein degradation

Orthologs

ID	Organism	Type
HUMAN\|HGNC=2422\|UniProtKB=O75390	Homo sapiens	LDO
PANTR\|Ensembl=ENSPTRG00000005090.5\|UniProtKB=K7BWL5	Pan troglodytes	LDO
GORGO\|Ensembl=ENSGGOG00000009096.3\|UniProtKB=G3S3T6	Gorilla gorilla gorilla	LDO
MACMU\|Ensembl=ENSMMUG00000002483.4\|UniProtKB=F7HGU4	Macaca mulatta	LDO
MOUSE\|MGI=MGI=1919082\|UniProtKB=Q80X68	Mus musculus	O
MOUSE\|MGI=MGI=88529\|UniProtKB=Q9CZU6	Mus musculus	LDO
RAT\|RGD=620330\|UniProtKB=Q8VHF5	Rattus norvegicus	LDO
BOVIN\|Ensembl=ENSBTAG00000004371\|UniProtKB=Q29RK1	Bos taurus	LDO
PIG\|Ensembl=ENSSSCG00000035686\|UniProtKB=P00889	Sus scrofa	LDO
HORSE\|Ensembl=ENSECAG00000016568.3\|UniProtKB=F6XMS1	Equus caballus	LDO
FELCA\|Ensembl=ENSFCAG00000012019.5\|UniProtKB=M3WG68	Felis catus	LDO
ORNAN\|Ensembl=ENSOANG00000031970.2\|UniProtKB=K7EC57	Ornithorhynchus anatinus	LDO
CHICK\|Ensembl=ENSGALG00010024933.1\|UniProtKB=A0A8V1A0Y3	Gallus gallus	LDO
ANOCA\|Ensembl=ENSACAG00000007556.4\|UniProtKB=G1KGV0	Anolis carolinensis	LDO
CHICK\|Gene=CS\|UniProtKB=P23007	Gallus gallus	O
XENLA\|Gene=cs\|UniProtKB=Q7ZWZ5	Xenopus laevis	O
XENLA\|Gene=cs.S\|UniProtKB=A0A1L8H9L7	Xenopus laevis	LDO
XENTR\|Xenbase=XB-GENE-943160\|UniProtKB=Q28DK1	Xenopus tropicalis	LDO
ORYLA\|Ensembl=ENSORLG00000015465.2\|UniProtKB=H2MKZ0	Oryzias latipes	LDO
DANRE\|ZFIN=ZDB-GENE-030131-1058\|UniProtKB=Q7ZVY5	Danio rerio	LDO
LEPOC\|Ensembl=ENSLOCG00000004655.1\|UniProtKB=W5MB20	lepisosteus oculatus	LDO
CIOIN\|Ensembl=ENSCING00000018403.1\|UniProtKB=H2XU13	Ciona intestinalis	LDO
BRAFL\|Gene_ORFName=BRAFLDRAFT_115230\|UniProtKB=C3Z8K7	Branchiostoma floridae	LDO
STRPU\|EnsemblGenome=LOC590444\|UniProtKB=A0A7M7P5Y2	Strongylocentrotus purpuratus	LDO
CAEEL\|WormBase=WBGene00000833\|UniProtKB=P34575	Caenorhabditis elegans	LDO
CAEBR\|WormBase=WBGene00031330\|UniProtKB=Q61JF9	Caenorhabditis briggsae	LDO
PRIPA\|EnsemblGenome=WBGene00092000\|UniProtKB=A0A454XLK2	Pristionchus pacificus	LDO
DROME\|FlyBase=FBgn0037988\|UniProtKB=Q95TZ4	Drosophila melanogaster	O
DROME\|FlyBase=FBgn0261955\|UniProtKB=Q9W401	Drosophila melanogaster	LDO
ANOGA\|EnsemblGenome=AGAP012048\|UniProtKB=Q7PV48	Anopheles gambiae	LDO
TRICA\|EnsemblGenome=TC033195\|UniProtKB=A0A139WHG4	Tribolium castaneum	O
TRICA\|EnsemblGenome=TC013214\|UniProtKB=D6WMM4	Tribolium castaneum	LDO
DAPPU\|EnsemblGenome=DAPPUDRAFT_299958\|UniProtKB=E9FRE7	Daphnia pulex	LDO
IXOSC\|EnsemblGenome=ISCW009586\|UniProtKB=B7Q3I2	Ixodes scapularis	LDO
HELRO\|EnsemblGenome=HelroG96242\|UniProtKB=T1G9B0	helobdella robusta	LDO
NEMVE\|EnsemblGenome=NEMVEDRAFT_v1g82156\|UniProtKB=A7RI62	Nematostella vectensis	LDO
TRIAD\|EnsemblGenome=TriadG54073\|UniProtKB=B3RR13	Trichoplax adhaerens	LDO
YEAST\|SGD=S000006205\|UniProtKB=P43635	Saccharomyces cerevisiae	O
EREGS\|EnsemblGenome=AGOS_AGR002W\|UniProtKB=Q750F3	Eremothecium gossypii	O
YARLI\|EnsemblGenome=YALI0_E00638g\|UniProtKB=Q6C7I2	Yarrowia lipolytica	O
EMENI\|EnsemblGenome=ANIA_06650\|UniProtKB=Q9TEM3	Emericella nidulans	O
ASPFU\|EnsemblGenome=AFUA_6G03590\|UniProtKB=E9QUP9	Neosartorya fumigata	O
NEUCR\|EnsemblGenome=NCU02482\|UniProtKB=V5IQA3	Neurospora crassa	O
SCLS1\|EnsemblGenome=SS1G_04899\|UniProtKB=A7EHV7	Sclerotinia sclerotiorum	O
PHANO\|EnsemblGenome=SNOG_07690\|UniProtKB=Q0UKM4	Phaeosphaeria nodorum	O
USTMA\|EnsemblGenome=UMAG_01627\|UniProtKB=A0A0D1CAY8	Ustilago maydis	O
PUCGT\|EnsemblGenome=PGTG_17180\|UniProtKB=E3L2Y3	Puccinia graminis	O
YEAST\|SGD=S000000598\|UniProtKB=P08679	Saccharomyces cerevisiae	O
YEAST\|SGD=S000005284\|UniProtKB=P00890	Saccharomyces cerevisiae	LDO
EREGS\|EnsemblGenome=AGOS_AAR004C\|UniProtKB=Q75ES5	Eremothecium gossypii	LDO
CANAL\|CGD=CAL0000197786\|UniProtKB=A0A1D8PSH3	Candida albicans	LDO
YARLI\|EnsemblGenome=YALI0_E02684g\|UniProtKB=Q6C793	Yarrowia lipolytica	LDO
EMENI\|EnsemblGenome=ANIA_08275\|UniProtKB=O00098	Emericella nidulans	LDO
ASPFU\|EnsemblGenome=AFUA_5G04230\|UniProtKB=Q4WEU5	Neosartorya fumigata	LDO
NEUCR\|EnsemblGenome=NCU01692\|UniProtKB=P34085	Neurospora crassa	LDO
SCLS1\|EnsemblGenome=SS1G_01625\|UniProtKB=A7E8J7	Sclerotinia sclerotiorum	LDO
PHANO\|EnsemblGenome=SNOG_01742\|UniProtKB=Q0V2M2	Phaeosphaeria nodorum	LDO
SCHPO\|PomBase=SPAC6C3.04\|UniProtKB=Q10306	Schizosaccharomyces pombe	LDO
SCHJY\|EnsemblGenome=SJAG_01922\|UniProtKB=B6JZ94	Schizosaccharomyces japonicus	LDO
CRYNJ\|EnsemblGenome=CNA00510\|UniProtKB=Q5KQ45	Cryptococcus neoformans	LDO
BATDJ\|Gene_ORFName=BATDEDRAFT_20166\|UniProtKB=F4P7B3	Batrachochytrium dendrobatidis	LDO
DICDI\|dictyBase=DDB_G0275311\|UniProtKB=Q553V1	Dictyostelium discoideum	LDO
DICPU\|EnsemblGenome=DICPUDRAFT_91550\|UniProtKB=F0ZE18	Dictyostelium purpureum	LDO
LEIMA\|EnsemblGenome=LMJF_18_0670\|UniProtKB=Q4QDX2	Leishmania major	O
LEIMA\|EnsemblGenome=LMJF_18_0680\|UniProtKB=Q4QDX3	Leishmania major	LDO
TRYB2\|Gene_ORFName=Tb10.05.0150\|UniProtKB=Q388Q5	Trypanosoma brucei	LDO
PLAF7\|EnsemblGenome=PF3D7_1022500\|UniProtKB=Q8I6U7	Plasmodium falciparum	LDO
PARTE\|EnsemblGenome=GSPATT00003586001\|UniProtKB=A0E606	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00003286001\|UniProtKB=A0DZ50	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00022347001\|UniProtKB=A0E1L0	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00004963001\|UniProtKB=A0BJ73	Paramecium tetraurelia	O
PARTE\|EnsemblGenome=GSPATT00020115001\|UniProtKB=A0DTR6	Paramecium tetraurelia	LDO
PARTE\|EnsemblGenome=GSPATT00000266001\|UniProtKB=Q6BFX3	Paramecium tetraurelia	O
THAPS\|EnsemblGenome=THAPSDRAFT_11411\|UniProtKB=B8CEG2	Thalassiosira pseudonana	LDO
PHYRM\|Gene=H3G951_PHYRM\|UniProtKB=H3G951	Phytophthora ramorum	LDO
CHLRE\|EnsemblGenome=CHLRE_12g514750v5\|UniProtKB=A8JHC9	Chlamydomonas reinhardtii	LDO
AMBTC\|EnsemblGenome=AMTR_s00131p00035560\|UniProtKB=W1NVN1	Amborella trichopoda	LDO
AMBTC\|EnsemblGenome=AMTR_s00025p00238170\|UniProtKB=W1PYP5	Amborella trichopoda	O
AMBTC\|EnsemblGenome=AMTR_s00025p00076740\|UniProtKB=W1PY00	Amborella trichopoda	O
ZOSMR\|Gene_ORFName=ZOSMA_221G00070\|UniProtKB=A0A0K9PJH8	Zostera marina	LDO
SETIT\|EnsemblGenome=SETIT_017002mg\|UniProtKB=K3YRV8	Setaria italica	LDO
SORBI\|EnsemblGenome=SORBI_3004G078000\|UniProtKB=A0A194YPD4	Sorghum bicolor	LDO
MAIZE\|EnsemblGenome=Zm00001eb206100\|UniProtKB=B4FIC0	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb206090\|UniProtKB=A0A1D6QRH7	Zea mays	O
MAIZE\|EnsemblGenome=Zm00001eb236450\|UniProtKB=B7ZWY9	Zea mays	LDO
ORYSJ\|EnsemblGenome=Os11g0538900\|UniProtKB=A0A0P0Y2X7	Oryza sativa	LDO
ORYSJ\|EnsemblGenome=Os02g0194100\|UniProtKB=Q7F8R1	Oryza sativa	LDO
BRADI\|EnsemblGenome=BRADI_3g06930v3\|UniProtKB=I1HYA2	Brachypodium distachyon	LDO
HORVV\|EnsemblGenome=HORVU.MOREX.r3.6HG0573820\|UniProtKB=M0Y818	Hordeum vulgare subsp. vulgare	LDO
WHEAT\|EnsemblGenome=TraesCS6B02G194700\|UniProtKB=A0A3B6PKC4	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS6D02G155800\|UniProtKB=A0A3B6QF83	Triticum aestivum	LDO
WHEAT\|EnsemblGenome=TraesCS6A02G167300\|UniProtKB=A0A3B6NNP8	Triticum aestivum	LDO
NELNU\|Gene=LOC104603546\|UniProtKB=A0A1U8AEB9	Nelumbo nucifera	LDO
SPIOL\|Gene=LOC110798295\|UniProtKB=A0A9R0K5D6	Spinacia oleracea	O
SPIOL\|Gene=LOC110783289\|UniProtKB=A0A9R0I5Q0	Spinacia oleracea	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr01g0027201\|UniProtKB=A0A9K3JVV9	Helianthus annuus	LDO
HELAN\|Gene_ORFName=HanXRQr2_Chr16g0759801\|UniProtKB=A0A9K3DSQ9	Helianthus annuus	O
HELAN\|Gene_ORFName=HannXRQ_Chr01g0018081\|UniProtKB=A0A251VRK6	Helianthus annuus	LDO
LACSA\|Gene_ORFName=LSAT_V11C400175130\|UniProtKB=A0A9R1VTH5	Lactuca sativa	O
LACSA\|Gene_ORFName=LSAT_V11C100035990\|UniProtKB=A0A9R1WJ90	Lactuca sativa	LDO
ERYGU\|Gene_ORFName=MIMGU_mgv1a005758mg\|UniProtKB=A0A022RQG2	Erythranthe guttata	LDO
CAPAN\|EnsemblGenome=T459_03016\|UniProtKB=A0A2G3ALM4	Capsicum annuum	LDO
SOLTU\|Gene=CISY_SOLTU\|UniProtKB=Q43175	Solanum tuberosum	O
SOLTU\|EnsemblGenome=PGSC0003DMG400028982\|UniProtKB=M1CTV7	Solanum tuberosum	LDO
SOLLC\|EnsemblGenome=Solyc01g073740.3\|UniProtKB=A0A3Q7EHA9	Solanum lycopersicum	LDO
TOBAC\|Gene=LOC107779254\|UniProtKB=A0A1S3YSJ7	Nicotiana tabacum	O
TOBAC\|Gene=LOC107791757\|UniProtKB=A0A1S3ZYE5	Nicotiana tabacum	LDO
VITVI\|EnsemblGenome=Vitvi13g01832\|UniProtKB=D7TNT9	Vitis vinifera	LDO
EUCGR\|EnsemblGenome=EUGRSUZ_G03428\|UniProtKB=A0A059BJ76	Eucalyptus grandis	O
EUCGR\|EnsemblGenome=EUGRSUZ_G03412\|UniProtKB=A0A059BJC8	Eucalyptus grandis	LDO
BRANA\|Gene_ORFName=DARMORV10_C04P32630.1\|UniProtKB=A0A078HXR9	Brassica napus	LDO
BRACM\|EnsemblGenome=Bra014513\|UniProtKB=M4DDE5	Brassica campestris	LDO
ARATH\|TAIR=locus=2101467\|UniProtKB=Q9M1D3	Arabidopsis thaliana	LDO
BRANA\|Gene_ORFName=DARMORV10_A04P33270.1\|UniProtKB=A0A078GVC1	Brassica napus	O
BRACM\|EnsemblGenome=Bra037657\|UniProtKB=A0A3P6D6C8	Brassica campestris	O
BRANA\|Gene_ORFName=DARMORV10_C04P70970.1\|UniProtKB=A0A078GFM5	Brassica napus	O
BRACM\|EnsemblGenome=Bra000351\|UniProtKB=M4C823	Brassica campestris	O
ARATH\|TAIR=locus=2050554\|UniProtKB=P20115	Arabidopsis thaliana	O
GOSHI\|Gene=LOC107913953\|UniProtKB=A0A1U8KBU4	Gossypium hirsutum	LDO
GOSHI\|Gene=LOC107905799\|UniProtKB=A0A1U8JHB6	Gossypium hirsutum	LDO
THECC\|EnsemblGenome=TCM_005948\|UniProtKB=A0A061DWK2	Theobroma cacao	LDO
CITSI\|Gene_ORFName=CISIN_1g012107mg\|UniProtKB=A0A067DSR4	Citrus sinensis	LDO
POPTR\|EnsemblGenome=POPTR_001G230500v3\|UniProtKB=B9N6I9	Populus trichocarpa	LDO
MANES\|EnsemblGenome=MANES_07G000500\|UniProtKB=A0A2C9VJ69	Manihot esculenta	O
MANES\|EnsemblGenome=MANES_10G152000\|UniProtKB=A0A2C9V6A9	Manihot esculenta	LDO
RICCO\|Gene_ORFName=RCOM_1774340\|UniProtKB=B9REL6	Ricinus communis	LDO
SOYBN\|EnsemblGenome=GLYMA_15G268500\|UniProtKB=I1MJI9	Glycine max	O
SOYBN\|EnsemblGenome=GLYMA_08G157700\|UniProtKB=I1KTQ4	Glycine max	LDO
MEDTR\|EnsemblGenome=MTR_2g061630\|UniProtKB=A0A072V8L1	Medicago truncatula	LDO
JUGRE\|EnsemblGenome=Jr15_07570\|UniProtKB=A0A2I4HPW3	Juglans regia	LDO
CUCSA\|EnsemblGenome=Csa_7G429590\|UniProtKB=A0A0A0K6P2	Cucumis sativus	LDO
PRUPE\|EnsemblGenome=PRUPE_2G002900\|UniProtKB=M5WZR5	Prunus persica	LDO
SELML\|EnsemblGenome=SELMODRAFT_146083\|UniProtKB=D8RD53	Selaginella moellendorffii	O
SELML\|EnsemblGenome=SELMODRAFT_228235\|UniProtKB=D8RSK2	Selaginella moellendorffii	LDO
PHYPA\|EnsemblGenome=Pp3c13_21410\|UniProtKB=A9RZ27	Physcomitrella patens	LDO
PHYPA\|EnsemblGenome=Pp3c1_40030\|UniProtKB=A0A7I4C514	Physcomitrella patens	O
MARPO\|EnsemblGenome=MARPO_0200s0007\|UniProtKB=A0A2R6W0M3	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0383s0001\|UniProtKB=A0A2R6VYZ0	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0216s0011\|UniProtKB=A0A2R6W000	Marchantia polymorpha	O
MARPO\|EnsemblGenome=MARPO_0063s0010\|UniProtKB=A0A2R6WRI0	Marchantia polymorpha	LDO
KLENI\|Gene_ORFName=KFL_000090420\|UniProtKB=A0A1Y1HNK8	Klebsormidium nitens	LDO
NITMS\|EnsemblGenome=Nmar_1099\|UniProtKB=A9A4L7	Nitrosopumilus maritimus	O
SACS2\|EnsemblGenome=SSO2589\|UniProtKB=P80148	Sulfolobus solfataricus	O
PYRAE\|EnsemblGenome=PAE3584\|UniProtKB=Q8ZSU1	Pyrobaculum aerophilum	O
PYRAE\|EnsemblGenome=PAE1689\|UniProtKB=Q8ZWP2	Pyrobaculum aerophilum	O
METAC\|EnsemblGenome=MA_0249\|UniProtKB=Q8TU25	Methanosarcina acetivorans	O
STRCO\|Gene_OrderedLocusName=SCO5832\|UniProtKB=O70008	Streptomyces coelicolor	O
STRCO\|Gene_OrderedLocusName=SCO4388\|UniProtKB=Q9K3V6	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=Rv0889c\|UniProtKB=P9WPD3	Mycobacterium tuberculosis	O
BRADU\|Gene=cis\|UniProtKB=Q89XX2	Bradyrhizobium diazoefficiens	O
STRCO\|Gene_OrderedLocusName=SCO5831\|UniProtKB=O70007	Streptomyces coelicolor	O
MYCTU\|Gene_OrderedLocusName=RVBD_1131\|UniProtKB=I6Y9Q3	Mycobacterium tuberculosis	O
STAA8\|EnsemblGenome=SAOUHSC_01802\|UniProtKB=Q2FXN3	Staphylococcus aureus	O
LISMO\|Gene=citZ\|UniProtKB=Q8Y6W4	Listeria monocytogenes	O
BACSU\|EnsemblGenome=BSU_24140\|UniProtKB=P45858	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_2285\|UniProtKB=Q81DS0	Bacillus cereus	O
BACSU\|EnsemblGenome=BSU_09440\|UniProtKB=P39119	Bacillus subtilis	O
BACSU\|EnsemblGenome=BSU_29140\|UniProtKB=P39120	Bacillus subtilis	O
BACCR\|EnsemblGenome=BC_4594\|UniProtKB=Q817F7	Bacillus cereus	O
THEMA\|EnsemblGenome=TM_0290\|UniProtKB=Q9WYC6	Thermotoga maritima	O
DEIRA\|EnsemblGenome=DR_0757\|UniProtKB=Q9RWB2	Deinococcus radiodurans	O
GLOVI\|Gene=Q7NCG7_GLOVI\|UniProtKB=Q7NCG7	Gloeobacter violaceus	O
SYNY3\|EnsemblGenome=BAA10262\|UniProtKB=Q59977	Synechocystis	O
BACTN\|EnsemblGenome=BT_2070\|UniProtKB=Q8A616	Bacteroides thetaiotaomicron	O
BRADU\|Gene=Q89GH1_BRADU\|UniProtKB=Q89GH1	Bradyrhizobium diazoefficiens	O
BRADU\|Gene=cisZ\|UniProtKB=Q89XX3	Bradyrhizobium diazoefficiens	O